http://togogenome.org/gene/333962:DQN80_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/333962:DQN80_RS17425 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA25 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/333962:DQN80_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/333962:DQN80_RS11700 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS15950 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A4D7INW0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/333962:DQN80_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/333962:DQN80_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/333962:DQN80_RS18980 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS15975 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9A7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/333962:DQN80_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZ91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/333962:DQN80_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS14180 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWT4 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/333962:DQN80_RS18080 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKQ5 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/333962:DQN80_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6R1 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/333962:DQN80_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7Y9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/333962:DQN80_RS13890 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMD3 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/333962:DQN80_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A4D7INH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/333962:DQN80_RS15955 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXA9 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/333962:DQN80_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/333962:DQN80_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A4D7J798 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/333962:DQN80_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/333962:DQN80_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/333962:DQN80_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2R0 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/333962:DQN80_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXC9 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/333962:DQN80_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4E3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPAT/DAPAT family.|||Cell membrane|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/333962:DQN80_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8W3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A4D7J708 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/333962:DQN80_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPZ6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Binds 1 zinc ion per subunit.|||Divalent metal cations. Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. http://togogenome.org/gene/333962:DQN80_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/333962:DQN80_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISG7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/333962:DQN80_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5K7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/333962:DQN80_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/333962:DQN80_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A4D7J094 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/333962:DQN80_RS15075 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX20 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/333962:DQN80_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYP7 ^@ Function|||Similarity ^@ Belongs to the group II decarboxylase family.|||Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria. http://togogenome.org/gene/333962:DQN80_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8H3 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/333962:DQN80_RS17030 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS15185 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS14045 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRU7 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITB8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/333962:DQN80_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIC5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/333962:DQN80_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLL4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/333962:DQN80_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLU7 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/333962:DQN80_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A4D7JE13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/333962:DQN80_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0L8 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis. http://togogenome.org/gene/333962:DQN80_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/333962:DQN80_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/333962:DQN80_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/333962:DQN80_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4V7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/333962:DQN80_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A4D7J700 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBH0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/333962:DQN80_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITD7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/333962:DQN80_RS14500 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A4D7J806 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2W8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS18885 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A4D7IKW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/333962:DQN80_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/333962:DQN80_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4U2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS19085 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9P1 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/333962:DQN80_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5X3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A4D7J814 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/333962:DQN80_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU18 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/333962:DQN80_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFC0 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/333962:DQN80_RS14850 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAB6 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/333962:DQN80_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A4D7J220 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/333962:DQN80_RS15305 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS16000 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPR6 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/333962:DQN80_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YscJ lipoprotein family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRL5 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/333962:DQN80_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUP2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4T9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A4D7JE62 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/333962:DQN80_RS11305 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7M8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/333962:DQN80_RS11575 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVU0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM86 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A4D7J604 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/333962:DQN80_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA22 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/333962:DQN80_RS11900 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS16155 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISV7 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS18210 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/333962:DQN80_RS15895 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXA4 ^@ Function|||Similarity ^@ Belongs to the peptidase C56 family.|||Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate. http://togogenome.org/gene/333962:DQN80_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A4D7J870 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/333962:DQN80_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. http://togogenome.org/gene/333962:DQN80_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A4D7J117 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/333962:DQN80_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.|||Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IgaA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A4D7J868 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/333962:DQN80_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX21 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18670 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/333962:DQN80_RS18640 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/333962:DQN80_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3S3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/333962:DQN80_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEA0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS16280 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/333962:DQN80_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXZ8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2B7 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/333962:DQN80_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/333962:DQN80_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4U4 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/333962:DQN80_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3A5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/333962:DQN80_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A4D7JH09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18560 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYG6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS16890 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS15625 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX78 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/333962:DQN80_RS17980 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/333962:DQN80_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A4D7J729 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/333962:DQN80_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISF3 ^@ Function|||Similarity|||Subunit ^@ A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.|||Belongs to the YihI family.|||Interacts with Der. http://togogenome.org/gene/333962:DQN80_RS14765 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS17430 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBJ1 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/333962:DQN80_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU47 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phospholipase A1 family.|||Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.|||Cell outer membrane|||Homodimer; dimerization is reversible, and the dimeric form is the active one.|||Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.|||Membrane http://togogenome.org/gene/333962:DQN80_RS14415 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8H9 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/333962:DQN80_RS18545 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9I0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB83 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS16915 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVC5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the organic radical-activating enzymes family.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM). http://togogenome.org/gene/333962:DQN80_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/333962:DQN80_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A4D7IKQ9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/333962:DQN80_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A4D7J472 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9S9 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/333962:DQN80_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITK8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/333962:DQN80_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM57 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/333962:DQN80_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/333962:DQN80_RS17000 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/333962:DQN80_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEJ8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW44 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/333962:DQN80_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/333962:DQN80_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A4D7J670 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/333962:DQN80_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4C8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/333962:DQN80_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVC0 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/333962:DQN80_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXB3 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/333962:DQN80_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIK0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6B7 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/333962:DQN80_RS19185 ^@ http://purl.uniprot.org/uniprot/A0A4D7J161 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR79 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/333962:DQN80_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A4D7IKX4 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/333962:DQN80_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18700 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHU3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/333962:DQN80_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecM family.|||Periplasm|||Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.|||cytosol http://togogenome.org/gene/333962:DQN80_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/333962:DQN80_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAH1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands. http://togogenome.org/gene/333962:DQN80_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A4D7J562 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/333962:DQN80_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG74 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/333962:DQN80_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1Y9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/333962:DQN80_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAE6 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.|||Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM. http://togogenome.org/gene/333962:DQN80_RS19540 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVZ2 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/333962:DQN80_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/333962:DQN80_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCX0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18175 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome. http://togogenome.org/gene/333962:DQN80_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7Z6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/333962:DQN80_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A4D7J518 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/333962:DQN80_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP25 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXW9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/333962:DQN80_RS16250 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0A4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS14475 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/333962:DQN80_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6G3 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/333962:DQN80_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/333962:DQN80_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA-modifying YgfZ family.|||Cytoplasm|||Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication. http://togogenome.org/gene/333962:DQN80_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRG7 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/333962:DQN80_RS18965 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm|||In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/333962:DQN80_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAE8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUZ0 ^@ Similarity ^@ Belongs to the EcpB/EcpE family. http://togogenome.org/gene/333962:DQN80_RS13545 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVT6 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS16385 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/333962:DQN80_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8T3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/333962:DQN80_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A4D7J839 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A4D7JD19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS15375 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFZ8 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/333962:DQN80_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A4D7INJ4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS14755 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJ05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/333962:DQN80_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS14340 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7R1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0E7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/333962:DQN80_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDT5 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/333962:DQN80_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS14455 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/333962:DQN80_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J583 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/333962:DQN80_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/333962:DQN80_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/333962:DQN80_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKS0 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/333962:DQN80_RS11395 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A4D7J624 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZipA family.|||Cell inner membrane|||Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.|||Interacts with FtsZ via their C-terminal domains. http://togogenome.org/gene/333962:DQN80_RS15595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J944 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS13480 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/333962:DQN80_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3E6 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/333962:DQN80_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB35 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/333962:DQN80_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUR7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/333962:DQN80_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILD3 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/333962:DQN80_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A4D7JH20 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2A3 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/333962:DQN80_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/333962:DQN80_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A4D7J865 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2F7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/333962:DQN80_RS17930 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/333962:DQN80_RS15415 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9J4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family.|||Binds 2 Fe(2+) ions per subunit.|||Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. http://togogenome.org/gene/333962:DQN80_RS19510 ^@ http://purl.uniprot.org/uniprot/A0A4D7JI96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm|||Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer. http://togogenome.org/gene/333962:DQN80_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A4D7J626 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/333962:DQN80_RS14225 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5Q0 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/333962:DQN80_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7K2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS18590 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUB9 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/333962:DQN80_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/333962:DQN80_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A4D7J768 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/333962:DQN80_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A4D7J738 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISG0 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/333962:DQN80_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18075 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/333962:DQN80_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/333962:DQN80_RS18335 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS11930 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXX2 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/333962:DQN80_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUC8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS16140 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAX8 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/333962:DQN80_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQF3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/333962:DQN80_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5R0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/333962:DQN80_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5I7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapB family.|||Binds 2 heme C groups per subunit.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0N1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/333962:DQN80_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A4D7J128 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A4D7J635 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/333962:DQN80_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A4D7J812 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS18415 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU74 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/333962:DQN80_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1F5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/333962:DQN80_RS14970 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A4D7J576 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/333962:DQN80_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV06 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/333962:DQN80_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3Z2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6B2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/333962:DQN80_RS11660 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8P1 ^@ Similarity ^@ Belongs to the UPF0339 family. Duplicated subfamily. http://togogenome.org/gene/333962:DQN80_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQ82 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/333962:DQN80_RS17860 ^@ http://purl.uniprot.org/uniprot/A0A4D7J981 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/333962:DQN80_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB01 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/333962:DQN80_RS17360 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBH9 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/333962:DQN80_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2K9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAX6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/333962:DQN80_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8P6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/333962:DQN80_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/333962:DQN80_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/333962:DQN80_RS15935 ^@ http://purl.uniprot.org/uniprot/A0A4D7J048 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/333962:DQN80_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/333962:DQN80_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3R2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/333962:DQN80_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYE2 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/333962:DQN80_RS11475 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUU9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LplA family.|||Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.|||Cytoplasm|||In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A4D7INV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBK7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/333962:DQN80_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/333962:DQN80_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/333962:DQN80_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIT1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/333962:DQN80_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4X1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/333962:DQN80_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAW2 ^@ Function|||Similarity ^@ Belongs to the FeoC family.|||May function as a transcriptional regulator that controls feoABC expression. http://togogenome.org/gene/333962:DQN80_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISE9 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/333962:DQN80_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRR9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/333962:DQN80_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVT1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWX4 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/333962:DQN80_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEW3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/333962:DQN80_RS18470 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 56 family.|||Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3X0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/333962:DQN80_RS18015 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0U0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/333962:DQN80_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/333962:DQN80_RS13530 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWG1 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/333962:DQN80_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5C5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/333962:DQN80_RS18775 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/333962:DQN80_RS11450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8H0 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/333962:DQN80_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXP1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09390 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/333962:DQN80_RS14050 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZA0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/333962:DQN80_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9T8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9I6 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. http://togogenome.org/gene/333962:DQN80_RS15875 ^@ http://purl.uniprot.org/uniprot/A0A4D7J039 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/333962:DQN80_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7P7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7E7 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/333962:DQN80_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5Z1 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/333962:DQN80_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A4D7IST9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWC3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVV6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/333962:DQN80_RS16035 ^@ http://purl.uniprot.org/uniprot/A0A4D7J065 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rnk family.|||Interacts with the RNA polymerase.|||May act as an anti-Gre factor. http://togogenome.org/gene/333962:DQN80_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITW1 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/333962:DQN80_RS19630 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/333962:DQN80_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LpoB family.|||Cell outer membrane|||Interacts with PBP1b.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). http://togogenome.org/gene/333962:DQN80_RS12850 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVK4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/333962:DQN80_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3E7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/333962:DQN80_RS15065 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/333962:DQN80_RS17960 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6W7 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/333962:DQN80_RS15050 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAE4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/333962:DQN80_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAH4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/333962:DQN80_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4Z8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/333962:DQN80_RS18390 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCR7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/333962:DQN80_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS14040 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8B2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBT5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAD3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/333962:DQN80_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPF9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/333962:DQN80_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/333962:DQN80_RS10795 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A4D7J835 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiC family.|||Cytoplasm|||Monomer.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/333962:DQN80_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A4D7IN97 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/333962:DQN80_RS10930 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2Y0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/333962:DQN80_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/333962:DQN80_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW98 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS14165 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18835 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY31 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/333962:DQN80_RS11525 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/333962:DQN80_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITD5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18795 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/333962:DQN80_RS18875 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6I2 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/333962:DQN80_RS11755 ^@ http://purl.uniprot.org/uniprot/A0A4D7JD48 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS14960 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS19570 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYZ4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CoA-transferase III family. Frc subfamily.|||Homodimer.|||Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3L2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/333962:DQN80_RS13625 ^@ http://purl.uniprot.org/uniprot/A0A4D7JI72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/333962:DQN80_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4P9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/333962:DQN80_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITJ8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/333962:DQN80_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM63 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYJ4 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/333962:DQN80_RS17390 ^@ http://purl.uniprot.org/uniprot/A0A4D7J908 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/333962:DQN80_RS12605 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQP9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/333962:DQN80_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT96 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/333962:DQN80_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITT9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/333962:DQN80_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC90 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT87 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/333962:DQN80_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8Y9 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/333962:DQN80_RS15890 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/333962:DQN80_RS14105 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS09655 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/333962:DQN80_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRD0 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/333962:DQN80_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A4D7J915 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/333962:DQN80_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/333962:DQN80_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A4D7JE27 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC18 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/333962:DQN80_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/333962:DQN80_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A4D7J275 ^@ Function|||Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.|||Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion. http://togogenome.org/gene/333962:DQN80_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18055 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/333962:DQN80_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family. RNase II subfamily.|||Cytoplasm|||Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. http://togogenome.org/gene/333962:DQN80_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A4D7J681 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/333962:DQN80_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS18170 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/333962:DQN80_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2U1 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/333962:DQN80_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU72 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/333962:DQN80_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS17735 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0R3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/333962:DQN80_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A4D7J830 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISG5 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/333962:DQN80_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6H6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/333962:DQN80_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVN7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/333962:DQN80_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT59 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/333962:DQN80_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW94 ^@ Similarity ^@ Belongs to the CcdB toxin family. http://togogenome.org/gene/333962:DQN80_RS14540 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZI9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/333962:DQN80_RS14460 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/333962:DQN80_RS19035 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9N4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS16045 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJN3 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/333962:DQN80_RS14470 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/333962:DQN80_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXP4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/333962:DQN80_RS18800 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/333962:DQN80_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6X2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/333962:DQN80_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6Z5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/333962:DQN80_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMB7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/333962:DQN80_RS12440 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/333962:DQN80_RS17810 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXS9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/333962:DQN80_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TamA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18330 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/333962:DQN80_RS16990 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/333962:DQN80_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2Q2 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/333962:DQN80_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A4D7J273 ^@ Caution|||Similarity ^@ Belongs to the phosphoglycerate mutase family. GpmB subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS15425 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG10 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/333962:DQN80_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBY3 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJ52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/333962:DQN80_RS16115 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXC7 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/333962:DQN80_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS88 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/333962:DQN80_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAE3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/333962:DQN80_RS16130 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFJ8 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/333962:DQN80_RS10800 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS03060 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8K2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT98 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITL4 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/333962:DQN80_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/333962:DQN80_RS11490 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8L9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArnE family.|||Cell inner membrane|||Heterodimer of ArnE and ArnF.|||Membrane|||Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. http://togogenome.org/gene/333962:DQN80_RS13410 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/333962:DQN80_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG79 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/333962:DQN80_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWQ8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/333962:DQN80_RS11620 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6H8 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/333962:DQN80_RS18010 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/333962:DQN80_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A4D7J659 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/333962:DQN80_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A4D7J526 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/333962:DQN80_RS17970 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKM8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/333962:DQN80_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3X3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/333962:DQN80_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISW5 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/333962:DQN80_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9N0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M20A family. ArgE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV72 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/333962:DQN80_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine. http://togogenome.org/gene/333962:DQN80_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6F3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/333962:DQN80_RS14510 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWW5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/333962:DQN80_RS19135 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLF2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS19080 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A4D7J799 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GhoT/OrtT toxin family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS18820 ^@ http://purl.uniprot.org/uniprot/A0A4D7JL95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPW9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/333962:DQN80_RS18185 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Homodimer.|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/333962:DQN80_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A4D7J572 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/333962:DQN80_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISE1 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.|||The transmembrane domain is a dimerization domain. http://togogenome.org/gene/333962:DQN80_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBE3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/333962:DQN80_RS16395 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A4D7J138 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/333962:DQN80_RS16375 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdD family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/333962:DQN80_RS15310 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWU2 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/333962:DQN80_RS14980 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8R8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISU4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/333962:DQN80_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA96 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. PhnX family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/333962:DQN80_RS14805 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXF0 ^@ Domain|||Function|||Subunit ^@ Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.|||Homodimer.|||Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. http://togogenome.org/gene/333962:DQN80_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILR8 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS19300 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/333962:DQN80_RS18410 ^@ http://purl.uniprot.org/uniprot/A0A4D7JKY9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/333962:DQN80_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/333962:DQN80_RS07200 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/333962:DQN80_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUX9 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/333962:DQN80_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/333962:DQN80_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3P8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/333962:DQN80_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A4D7IST4 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5M0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/333962:DQN80_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB06 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/333962:DQN80_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/333962:DQN80_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS19005 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18180 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0V6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/333962:DQN80_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG50 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Cell membrane|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/333962:DQN80_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A4D7J149 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/333962:DQN80_RS16270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/333962:DQN80_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS11640 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVM9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/333962:DQN80_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18880 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB17 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/333962:DQN80_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A4D7J848 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/333962:DQN80_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A4D7INC1 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/333962:DQN80_RS14285 ^@ http://purl.uniprot.org/uniprot/A0A4D7J947 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/333962:DQN80_RS18760 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/333962:DQN80_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 9 family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS18790 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYR3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class B bacterial acid phosphatase family.|||Binds 1 Mg(2+) ion per subunit.|||Homotetramer.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS19590 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/333962:DQN80_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAH0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/333962:DQN80_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/333962:DQN80_RS15395 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJB4 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/333962:DQN80_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3V4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/333962:DQN80_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUL6 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/333962:DQN80_RS15480 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/333962:DQN80_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A4D7J971 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/333962:DQN80_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY08 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/333962:DQN80_RS18205 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAF3 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/333962:DQN80_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT92 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/333962:DQN80_RS18945 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAN1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGZ4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/333962:DQN80_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR25 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/333962:DQN80_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHH1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/333962:DQN80_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6Q4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/333962:DQN80_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8I1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS14305 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/333962:DQN80_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBZ0 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/333962:DQN80_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4Q6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/333962:DQN80_RS18645 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/333962:DQN80_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITH3 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/333962:DQN80_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/333962:DQN80_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA86 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS13920 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF77 ^@ Similarity|||Subunit ^@ Belongs to the glutaredoxin family.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS04240 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZ37 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS14420 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/333962:DQN80_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A4D7IME1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/333962:DQN80_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7F3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Binds two Mg(2+) per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/333962:DQN80_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4F4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4D8 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/333962:DQN80_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6V9 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/333962:DQN80_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS03800 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2G9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/333962:DQN80_RS16945 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8U4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/333962:DQN80_RS18830 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVC3 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/333962:DQN80_RS15380 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8Z9 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/333962:DQN80_RS03595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J547 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/333962:DQN80_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A4D7J458 ^@ Similarity ^@ Belongs to the complex I 24 kDa subunit family. http://togogenome.org/gene/333962:DQN80_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS18845 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/333962:DQN80_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.|||Catalyzes the proton-dependent transport of glutamate and aspartate.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A4D7INT1 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/333962:DQN80_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS19140 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUL9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS16025 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/333962:DQN80_RS19470 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLN0 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/333962:DQN80_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5E2 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/333962:DQN80_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV81 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/333962:DQN80_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9Q6 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/333962:DQN80_RS09115 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0266 family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXV9 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/333962:DQN80_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/333962:DQN80_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/333962:DQN80_RS19285 ^@ http://purl.uniprot.org/uniprot/A0A4D7JI57 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/333962:DQN80_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQU1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/333962:DQN80_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISZ9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS14375 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/333962:DQN80_RS13075 ^@ http://purl.uniprot.org/uniprot/A0A4D7J998 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7D0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CopC family.|||Involved in copper resistance.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP31 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/333962:DQN80_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4A6 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the maleate isomerase family.|||Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.|||Homodimer.|||Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate. http://togogenome.org/gene/333962:DQN80_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/333962:DQN80_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISK6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7Y5 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/333962:DQN80_RS15465 ^@ http://purl.uniprot.org/uniprot/A0A4D7J853 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/333962:DQN80_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQ27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5A9 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/333962:DQN80_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS13745 ^@ http://purl.uniprot.org/uniprot/A0A4D7J860 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8N4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/333962:DQN80_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/333962:DQN80_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A4D7J086 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS19175 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A4D7JH19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/333962:DQN80_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A4D7J433 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS14265 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7G8 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/333962:DQN80_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A4D7JE11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM20 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/333962:DQN80_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/333962:DQN80_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A4D7J444 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS13730 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8W7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS15115 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS13790 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS19165 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYS6 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/333962:DQN80_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/333962:DQN80_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1P0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4L3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/333962:DQN80_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4N8 ^@ Function|||Similarity ^@ Belongs to the bacterial-type ferredoxin family. FixX subfamily.|||Could be a 3Fe-4S cluster-containing protein. http://togogenome.org/gene/333962:DQN80_RS14840 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFQ1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A4D7J393 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/333962:DQN80_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMI6 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/333962:DQN80_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPK6 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS14885 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVI2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/333962:DQN80_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3D5 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/333962:DQN80_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/333962:DQN80_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A4D7J463 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A4D7JH58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISS0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/333962:DQN80_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3M9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUU1 ^@ Similarity ^@ Belongs to the DnaA family. http://togogenome.org/gene/333962:DQN80_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A4D7J811 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1W1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/333962:DQN80_RS15135 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVB5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/333962:DQN80_RS10685 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVD0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHB9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS13515 ^@ http://purl.uniprot.org/uniprot/A0A4D7JI52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/333962:DQN80_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQ45 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/333962:DQN80_RS08880 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBS4 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/333962:DQN80_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDP8 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/333962:DQN80_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5Y2 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEH9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/333962:DQN80_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVP6 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/333962:DQN80_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQL2 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/333962:DQN80_RS18815 ^@ http://purl.uniprot.org/uniprot/A0A4D7J126 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/333962:DQN80_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCX9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/333962:DQN80_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS27 ^@ Activity Regulation|||Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.|||Belongs to the TPP enzyme family.|||Binds 1 FAD per subunit.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Cell membrane|||Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus. http://togogenome.org/gene/333962:DQN80_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5R8 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/333962:DQN80_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS19450 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCR4 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/333962:DQN80_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6Y6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/333962:DQN80_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.|||Cell inner membrane|||Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).|||Membrane|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/333962:DQN80_RS17965 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0T4 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/333962:DQN80_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRK3 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/333962:DQN80_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVC4 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/333962:DQN80_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A4D7J181 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/333962:DQN80_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A4D7J990 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/333962:DQN80_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5T4 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/333962:DQN80_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS49 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family. http://togogenome.org/gene/333962:DQN80_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM78 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/333962:DQN80_RS13980 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF85 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family. http://togogenome.org/gene/333962:DQN80_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUN5 ^@ Similarity ^@ Belongs to the MscS (TC 1.A.23) family. http://togogenome.org/gene/333962:DQN80_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. RsmC family.|||Cytoplasm|||Monomer.|||Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. http://togogenome.org/gene/333962:DQN80_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9B5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/333962:DQN80_RS16935 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT69 ^@ Similarity ^@ Belongs to the CcmL/EutN family. http://togogenome.org/gene/333962:DQN80_RS15570 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HdeB family.|||Periplasm|||Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. http://togogenome.org/gene/333962:DQN80_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A4D7J254 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/333962:DQN80_RS18565 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHR6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/333962:DQN80_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/333962:DQN80_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT34 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/333962:DQN80_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/333962:DQN80_RS18810 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/333962:DQN80_RS16055 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8E6 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/333962:DQN80_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB86 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/333962:DQN80_RS15180 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9G2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Xni family.|||Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.|||Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.|||Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. http://togogenome.org/gene/333962:DQN80_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6E5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/333962:DQN80_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCN2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/333962:DQN80_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A4D7JK69 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6B3 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/333962:DQN80_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF97 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/333962:DQN80_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/333962:DQN80_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2B0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18530 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/333962:DQN80_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISC5 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/333962:DQN80_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS15945 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISR1 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/333962:DQN80_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A4D7IML8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13090 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR19 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/333962:DQN80_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUD6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/333962:DQN80_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A4D7J055 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISK7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/333962:DQN80_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/333962:DQN80_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A4D7J658 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/333962:DQN80_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TonB family.|||Cell inner membrane|||Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/333962:DQN80_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A4D7INR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/333962:DQN80_RS18735 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY18 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZ51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/333962:DQN80_RS15405 ^@ http://purl.uniprot.org/uniprot/A0A4D7J845 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/333962:DQN80_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0Z9 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/333962:DQN80_RS14810 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJ15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/333962:DQN80_RS15455 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS16060 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease N1/T1 family.|||Secreted http://togogenome.org/gene/333962:DQN80_RS18000 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A4D7J577 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/333962:DQN80_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMJ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. http://togogenome.org/gene/333962:DQN80_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2Q6 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/333962:DQN80_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/333962:DQN80_RS19055 ^@ http://purl.uniprot.org/uniprot/A0A4D7JI08 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/333962:DQN80_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4H7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/333962:DQN80_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQ85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC30 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/333962:DQN80_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/333962:DQN80_RS16450 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/333962:DQN80_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18585 ^@ http://purl.uniprot.org/uniprot/A0A4D7JL26 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/333962:DQN80_RS11705 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6T5 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/333962:DQN80_RS16765 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS11570 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWQ9 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/333962:DQN80_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A4D7J439 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/333962:DQN80_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A4D7J052 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/333962:DQN80_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A4D7J336 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/333962:DQN80_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4Q1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane|||The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains. http://togogenome.org/gene/333962:DQN80_RS14695 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIZ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/333962:DQN80_RS16430 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/333962:DQN80_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A4D7J488 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/333962:DQN80_RS15300 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WzyE family.|||Cell inner membrane|||Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/333962:DQN80_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4E1 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/333962:DQN80_RS14055 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A4D7JL71 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/333962:DQN80_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A4D7INU2 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/333962:DQN80_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC82 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/333962:DQN80_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A4D7J113 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILG4 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/333962:DQN80_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A4D7INN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISE7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/333962:DQN80_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3U1 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/333962:DQN80_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGM8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS15295 ^@ http://purl.uniprot.org/uniprot/A0A4D7J827 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXG0 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/333962:DQN80_RS18540 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/333962:DQN80_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWL2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A4D7J963 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).|||Membrane http://togogenome.org/gene/333962:DQN80_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18745 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/333962:DQN80_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A4D7J392 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0312 family. Type 1 subfamily.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3I8 ^@ Similarity ^@ Belongs to the protease inhibitor I11 (ecotin) family. http://togogenome.org/gene/333962:DQN80_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A4D7J407 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/333962:DQN80_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/333962:DQN80_RS14205 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA09 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/333962:DQN80_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/333962:DQN80_RS17755 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS19155 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY55 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/333962:DQN80_RS18680 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/333962:DQN80_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A4D7JD12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/333962:DQN80_RS14585 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/333962:DQN80_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4Y4 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/333962:DQN80_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4T8 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/333962:DQN80_RS15490 ^@ http://purl.uniprot.org/uniprot/A0A4D7J919 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/333962:DQN80_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS18705 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/333962:DQN80_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQT8 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/333962:DQN80_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8P5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/333962:DQN80_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILR6 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/333962:DQN80_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/333962:DQN80_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A4D7J957 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/333962:DQN80_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A4D7J758 ^@ Function|||Similarity ^@ Belongs to the thiamine kinase family.|||Catalyzes the phosphorylation of thiamine to thiamine phosphate. http://togogenome.org/gene/333962:DQN80_RS14515 ^@ http://purl.uniprot.org/uniprot/A0A4D7J980 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/333962:DQN80_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYP2 ^@ Function|||Induction|||PTM|||Similarity|||Subunit ^@ Belongs to the SulA family.|||By DNA damage, as part of the SOS response.|||Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.|||Interacts with FtsZ.|||Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired. http://togogenome.org/gene/333962:DQN80_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITC9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAZ8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS17345 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A4D7INW4 ^@ Similarity|||Subunit ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/333962:DQN80_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITP9 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/333962:DQN80_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA67 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/333962:DQN80_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18995 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAN7 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/333962:DQN80_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A4D7J719 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/333962:DQN80_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPM9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.|||Catalyzes the excretion of spermidine.|||Cell membrane|||Forms a complex with MdtI.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J396 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/333962:DQN80_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS39 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/333962:DQN80_RS14300 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFF4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/333962:DQN80_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A4D7J558 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acyl-CoA dehydrogenase family.|||Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS15210 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZT8 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/333962:DQN80_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMX9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/333962:DQN80_RS00600 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS16325 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/333962:DQN80_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0W3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/333962:DQN80_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM10 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/333962:DQN80_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9U2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09110 ^@ http://purl.uniprot.org/uniprot/A0A4D7J553 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/333962:DQN80_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJU9 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/333962:DQN80_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.|||Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISH6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/333962:DQN80_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/333962:DQN80_RS15535 ^@ http://purl.uniprot.org/uniprot/A0A4D7JG30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A4D7JE03 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/333962:DQN80_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS11535 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/333962:DQN80_RS14270 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRS6 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/333962:DQN80_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAC5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/333962:DQN80_RS16370 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/333962:DQN80_RS07115 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISD8 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||Binds 1 FAD per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A4D7J2S3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV22 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/333962:DQN80_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A4D7IV03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/333962:DQN80_RS18990 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY40 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/333962:DQN80_RS18770 ^@ http://purl.uniprot.org/uniprot/A0A4D7JL81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQ73 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/333962:DQN80_RS18825 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUH5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/333962:DQN80_RS19595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1A6 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/333962:DQN80_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS14280 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/333962:DQN80_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISV1 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/333962:DQN80_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7E9 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/333962:DQN80_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A4D7J434 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/333962:DQN80_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8M9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/333962:DQN80_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5Q5 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/333962:DQN80_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS14825 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWZ7 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/333962:DQN80_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Cell membrane|||Membrane|||Rhomboid-type serine protease that catalyzes intramembrane proteolysis. http://togogenome.org/gene/333962:DQN80_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Cell membrane|||Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A4D7J849 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/333962:DQN80_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEF6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A4D7J772 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCC4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5X5 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/333962:DQN80_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/333962:DQN80_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBW9 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/333962:DQN80_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/333962:DQN80_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A4D7J752 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/333962:DQN80_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU73 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands. http://togogenome.org/gene/333962:DQN80_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/333962:DQN80_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/333962:DQN80_RS11360 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7P2 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/333962:DQN80_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A4D7J931 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/333962:DQN80_RS15505 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJD5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/333962:DQN80_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4M3 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/333962:DQN80_RS16715 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/333962:DQN80_RS14330 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRT5 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/333962:DQN80_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAA7 ^@ Function|||Similarity ^@ Belongs to the arginase family. Agmatinase subfamily.|||Catalyzes the formation of putrescine from agmatine. http://togogenome.org/gene/333962:DQN80_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A4D7J376 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS17005 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8V1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A4D7J694 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/333962:DQN80_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISH8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/333962:DQN80_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A4D7J110 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/333962:DQN80_RS15110 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJ61 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/333962:DQN80_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7Z0 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/333962:DQN80_RS16950 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/333962:DQN80_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/333962:DQN80_RS18755 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/333962:DQN80_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A4D7J114 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/333962:DQN80_RS14315 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZF0 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS63 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/333962:DQN80_RS19100 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYR5 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/333962:DQN80_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITK1 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/333962:DQN80_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A4D7JF55 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/333962:DQN80_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS18240 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS19025 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLD0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/333962:DQN80_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEX3 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/333962:DQN80_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A4D7J217 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/333962:DQN80_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.|||Cell membrane|||Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A4D7IP05 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/333962:DQN80_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8P9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A4D7IXB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Cell inner membrane|||Membrane|||Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake. http://togogenome.org/gene/333962:DQN80_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS19635 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/333962:DQN80_RS14520 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWF9 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/333962:DQN80_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS15120 ^@ http://purl.uniprot.org/uniprot/A0A4D7J805 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/333962:DQN80_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3H7 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/333962:DQN80_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/333962:DQN80_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A4D7J591 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/333962:DQN80_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYN5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A4D7INF6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/333962:DQN80_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHF8 ^@ Similarity ^@ Belongs to the CitG/MdcB family. http://togogenome.org/gene/333962:DQN80_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPU0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/333962:DQN80_RS14395 ^@ http://purl.uniprot.org/uniprot/A0A4D7IWV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS15515 ^@ http://purl.uniprot.org/uniprot/A0A4D7J864 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/333962:DQN80_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A4D7JEU6 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/333962:DQN80_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/333962:DQN80_RS11565 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/333962:DQN80_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7X6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrE/TusD family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. http://togogenome.org/gene/333962:DQN80_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapF family.|||Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/333962:DQN80_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1M6 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/333962:DQN80_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX51 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/333962:DQN80_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIX8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/333962:DQN80_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZ05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/333962:DQN80_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7E5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/333962:DQN80_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX02 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/333962:DQN80_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS19585 ^@ http://purl.uniprot.org/uniprot/A0A4D7JBC3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CoA-transferase III family. Frc subfamily.|||Homodimer.|||Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZ29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TrpR family.|||Cytoplasm|||Homodimer.|||This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. http://togogenome.org/gene/333962:DQN80_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS13690 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYH6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS12765 ^@ http://purl.uniprot.org/uniprot/A0A4D7JHS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/333962:DQN80_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAL4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/333962:DQN80_RS16445 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9W5 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/333962:DQN80_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU41 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/333962:DQN80_RS14760 ^@ http://purl.uniprot.org/uniprot/A0A4D7IZE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT11 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/333962:DQN80_RS13925 ^@ http://purl.uniprot.org/uniprot/A0A4D7J892 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/333962:DQN80_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1I9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/333962:DQN80_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A4D7J162 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/333962:DQN80_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITT6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/333962:DQN80_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS05 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/333962:DQN80_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/333962:DQN80_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6Y9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A4D7IME7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18555 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRA3 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/333962:DQN80_RS13935 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9V6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6D1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/333962:DQN80_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AFG1 ATPase family. ZapE subfamily.|||Cytoplasm|||Interacts with FtsZ.|||Reduces the stability of FtsZ polymers in the presence of ATP. http://togogenome.org/gene/333962:DQN80_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/333962:DQN80_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUL4 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/333962:DQN80_RS18725 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/333962:DQN80_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A4D7J229 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/333962:DQN80_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/333962:DQN80_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISI4 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/333962:DQN80_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.|||Cell inner membrane|||Interacts with KefB.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. http://togogenome.org/gene/333962:DQN80_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J614 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A4D7J455 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/333962:DQN80_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM72 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/333962:DQN80_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAG1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/333962:DQN80_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/333962:DQN80_RS18220 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/333962:DQN80_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4I7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/333962:DQN80_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS16175 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX94 ^@ Function|||Similarity ^@ Belongs to the CsgG family.|||May be involved in the biogenesis of curli organelles. http://togogenome.org/gene/333962:DQN80_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/333962:DQN80_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM34 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/333962:DQN80_RS14530 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8J6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. http://togogenome.org/gene/333962:DQN80_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4N0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/333962:DQN80_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS14110 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/333962:DQN80_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8U3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/333962:DQN80_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6B6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6N0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/333962:DQN80_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/333962:DQN80_RS19075 ^@ http://purl.uniprot.org/uniprot/A0A4D7JLE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/333962:DQN80_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/333962:DQN80_RS16110 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8F5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/333962:DQN80_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8Q7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/333962:DQN80_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUR2 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/333962:DQN80_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8N2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS16210 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A4D7INW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/333962:DQN80_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGV9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/333962:DQN80_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A4D7J513 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/333962:DQN80_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/333962:DQN80_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQL9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/333962:DQN80_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A4D7IYJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQH0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A4D7IPY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/333962:DQN80_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUR6 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/333962:DQN80_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A4D7JA70 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/333962:DQN80_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/333962:DQN80_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJS8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/333962:DQN80_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8Y4 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/333962:DQN80_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A4D7ILL0 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/333962:DQN80_RS18195 ^@ http://purl.uniprot.org/uniprot/A0A4D7J9D5 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. http://togogenome.org/gene/333962:DQN80_RS18660 ^@ http://purl.uniprot.org/uniprot/A0A4D7J107 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/333962:DQN80_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6K6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/333962:DQN80_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4G3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HemG family.|||Binds 1 FMN non-covalently per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU50 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/333962:DQN80_RS11385 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDG0 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/333962:DQN80_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A4D7IX44 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/333962:DQN80_RS11760 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6U8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/333962:DQN80_RS15090 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR97 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/333962:DQN80_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A4D7J5W1 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/333962:DQN80_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A4D7J3G5 ^@ Similarity ^@ Belongs to the UPF0149 family. http://togogenome.org/gene/333962:DQN80_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A4D7JDA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/333962:DQN80_RS15495 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/333962:DQN80_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS04285 ^@ http://purl.uniprot.org/uniprot/A0A4D7J967 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/333962:DQN80_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dGTPase family. Type 1 subfamily.|||Homotetramer.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/333962:DQN80_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVF8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/333962:DQN80_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/333962:DQN80_RS15925 ^@ http://purl.uniprot.org/uniprot/A0A4D7J997 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/333962:DQN80_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0E3 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/333962:DQN80_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/333962:DQN80_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A4D7IMH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1K5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/333962:DQN80_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCZ1 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/333962:DQN80_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A4D7J710 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/333962:DQN80_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW27 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/333962:DQN80_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A4D7IR81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/333962:DQN80_RS19640 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCU3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/333962:DQN80_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A4D7IU54 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/333962:DQN80_RS12420 ^@ http://purl.uniprot.org/uniprot/A0A4D7J765 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/333962:DQN80_RS15920 ^@ http://purl.uniprot.org/uniprot/A0A4D7JGA8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/333962:DQN80_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A4D7J8M6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/333962:DQN80_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0L5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A4D7JL11 ^@ Function|||Similarity ^@ Belongs to the GppA/Ppx family. GppA subfamily.|||Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. http://togogenome.org/gene/333962:DQN80_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A4D7ISX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A4D7IQH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITC1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/333962:DQN80_RS17450 ^@ http://purl.uniprot.org/uniprot/A0A4D7J917 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/333962:DQN80_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVW4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/333962:DQN80_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/333962:DQN80_RS17815 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAA4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/333962:DQN80_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS56 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/333962:DQN80_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A4D7J420 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/333962:DQN80_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUN1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Multidrug efflux pump that functions probably as a Na(+)/drug antiporter. http://togogenome.org/gene/333962:DQN80_RS15000 ^@ http://purl.uniprot.org/uniprot/A0A4D7JJ44 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/333962:DQN80_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS13885 ^@ http://purl.uniprot.org/uniprot/A0A4D7JIJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A4D7J263 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/333962:DQN80_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRK9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/333962:DQN80_RS18225 ^@ http://purl.uniprot.org/uniprot/A0A4D7JC20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/333962:DQN80_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A4D7JB15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/333962:DQN80_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A4D7JAF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/333962:DQN80_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/333962:DQN80_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A4D7IM95 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/333962:DQN80_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A4D7J6U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/333962:DQN80_RS06045 ^@ http://purl.uniprot.org/uniprot/A0A4D7IRZ1 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/333962:DQN80_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A4D7J410 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/333962:DQN80_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A4D7J7Q0 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/333962:DQN80_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A4D7J0A6 ^@ Similarity|||Subunit ^@ Belongs to the ViaA family.|||Possible formation of a ternary complex RavA-ViaA-CadA. http://togogenome.org/gene/333962:DQN80_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A4D7J1D3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the exbB/tolQ family.|||Cell inner membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/333962:DQN80_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A4D7J4H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/333962:DQN80_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A4D7J788 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/333962:DQN80_RS18785 ^@ http://purl.uniprot.org/uniprot/A0A4D7IY22 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/333962:DQN80_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A4D7INJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/333962:DQN80_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A4D7J381 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively. http://togogenome.org/gene/333962:DQN80_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A4D7JFG3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/333962:DQN80_RS17385 ^@ http://purl.uniprot.org/uniprot/A0A4D7ITH5 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/333962:DQN80_RS13795 ^@ http://purl.uniprot.org/uniprot/A0A4D7IW38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/333962:DQN80_RS10750 ^@ http://purl.uniprot.org/uniprot/A0A4D7JCY0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/333962:DQN80_RS14815 ^@ http://purl.uniprot.org/uniprot/A0A4D7IS29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/333962:DQN80_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A4D7IUD2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/333962:DQN80_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A4D7IT05 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/333962:DQN80_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A4D7IVC7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)).