http://togogenome.org/gene/335543:SFUM_RS20375 ^@ http://purl.uniprot.org/uniprot/A0LQB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13725 ^@ http://purl.uniprot.org/uniprot/A0LLM2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS01360 ^@ http://purl.uniprot.org/uniprot/A0LEW5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS14060 ^@ http://purl.uniprot.org/uniprot/A0LLT9 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/335543:SFUM_RS06285 ^@ http://purl.uniprot.org/uniprot/A0LHJ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/335543:SFUM_RS08295 ^@ http://purl.uniprot.org/uniprot/A0LIP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/335543:SFUM_RS01595 ^@ http://purl.uniprot.org/uniprot/A0LF12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03715 ^@ http://purl.uniprot.org/uniprot/A0LG61 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/335543:SFUM_RS00630 ^@ http://purl.uniprot.org/uniprot/A0LEG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS01070 ^@ http://purl.uniprot.org/uniprot/A0LEQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13915 ^@ http://purl.uniprot.org/uniprot/A0LLR0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NifU family.|||Binds 1 Fe cation per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. http://togogenome.org/gene/335543:SFUM_RS01235 ^@ http://purl.uniprot.org/uniprot/A0LEU0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03970 ^@ http://purl.uniprot.org/uniprot/A0LGA8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/335543:SFUM_RS01570 ^@ http://purl.uniprot.org/uniprot/A0LF07 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/335543:SFUM_RS12110 ^@ http://purl.uniprot.org/uniprot/A0LKR9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/335543:SFUM_RS01345 ^@ http://purl.uniprot.org/uniprot/A0LEW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/335543:SFUM_RS16065 ^@ http://purl.uniprot.org/uniprot/A0LMX7 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/335543:SFUM_RS01405 ^@ http://purl.uniprot.org/uniprot/A0LEX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/335543:SFUM_RS14210 ^@ http://purl.uniprot.org/uniprot/A0LLX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS08825 ^@ http://purl.uniprot.org/uniprot/A0LIZ3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/335543:SFUM_RS15085 ^@ http://purl.uniprot.org/uniprot/A0LMD1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13415 ^@ http://purl.uniprot.org/uniprot/A0LLG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. http://togogenome.org/gene/335543:SFUM_RS13910 ^@ http://purl.uniprot.org/uniprot/A0LLQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS08225 ^@ http://purl.uniprot.org/uniprot/A0LIM5 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/335543:SFUM_RS15445 ^@ http://purl.uniprot.org/uniprot/A0LMK1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/335543:SFUM_RS00720 ^@ http://purl.uniprot.org/uniprot/A0LEI8 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/335543:SFUM_RS20180 ^@ http://purl.uniprot.org/uniprot/A0LQ78 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS01565 ^@ http://purl.uniprot.org/uniprot/A0LF05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS21285 ^@ http://purl.uniprot.org/uniprot/A0LFQ3 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/335543:SFUM_RS08845 ^@ http://purl.uniprot.org/uniprot/A0LIZ7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS03815 ^@ http://purl.uniprot.org/uniprot/A0LG79 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS21900 ^@ http://purl.uniprot.org/uniprot/A0LLW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/335543:SFUM_RS22170 ^@ http://purl.uniprot.org/uniprot/A0LPQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07220 ^@ http://purl.uniprot.org/uniprot/A0LI29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14265 ^@ http://purl.uniprot.org/uniprot/A0LLX9 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/335543:SFUM_RS15550 ^@ http://purl.uniprot.org/uniprot/A0LMM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/335543:SFUM_RS11020 ^@ http://purl.uniprot.org/uniprot/A0LK59 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS11505 ^@ http://purl.uniprot.org/uniprot/A0LKF2 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS20260 ^@ http://purl.uniprot.org/uniprot/A0LQ94 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/335543:SFUM_RS00780 ^@ http://purl.uniprot.org/uniprot/A0LEK0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/335543:SFUM_RS20550 ^@ http://purl.uniprot.org/uniprot/A0LQF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10270 ^@ http://purl.uniprot.org/uniprot/A0LJR5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/335543:SFUM_RS07935 ^@ http://purl.uniprot.org/uniprot/A0LIG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13455 ^@ http://purl.uniprot.org/uniprot/A0LLH0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/335543:SFUM_RS09930 ^@ http://purl.uniprot.org/uniprot/A0LJK6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/335543:SFUM_RS19720 ^@ http://purl.uniprot.org/uniprot/A0LPY2 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/335543:SFUM_RS09835 ^@ http://purl.uniprot.org/uniprot/A0LJI8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/335543:SFUM_RS00655 ^@ http://purl.uniprot.org/uniprot/A0LEH4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/335543:SFUM_RS08020 ^@ http://purl.uniprot.org/uniprot/A0LII3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/335543:SFUM_RS05005 ^@ http://purl.uniprot.org/uniprot/A0LGV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18605 ^@ http://purl.uniprot.org/uniprot/A0LPC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS01875 ^@ http://purl.uniprot.org/uniprot/A0LF66 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/335543:SFUM_RS15965 ^@ http://purl.uniprot.org/uniprot/A0LMV7 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/335543:SFUM_RS12290 ^@ http://purl.uniprot.org/uniprot/A0LKV5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS10805 ^@ http://purl.uniprot.org/uniprot/A0LK18 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/335543:SFUM_RS14005 ^@ http://purl.uniprot.org/uniprot/A0LLS9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/335543:SFUM_RS16805 ^@ http://purl.uniprot.org/uniprot/A0LNC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS09405 ^@ http://purl.uniprot.org/uniprot/A0LJA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/335543:SFUM_RS23535 ^@ http://purl.uniprot.org/uniprot/A0LJR7 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS02305 ^@ http://purl.uniprot.org/uniprot/A0LFE8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS02485 ^@ http://purl.uniprot.org/uniprot/A0LFI2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/335543:SFUM_RS10000 ^@ http://purl.uniprot.org/uniprot/A0LJL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS18840 ^@ http://purl.uniprot.org/uniprot/A0LPG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS15360 ^@ http://purl.uniprot.org/uniprot/A0LMI4 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/335543:SFUM_RS11050 ^@ http://purl.uniprot.org/uniprot/A0LK65 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS18380 ^@ http://purl.uniprot.org/uniprot/A0LP77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00290 ^@ http://purl.uniprot.org/uniprot/A0LEA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. Can also use m-DAP instead of LL-DAP as the amino-group donor. http://togogenome.org/gene/335543:SFUM_RS05985 ^@ http://purl.uniprot.org/uniprot/A0LHE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS12350 ^@ http://purl.uniprot.org/uniprot/A0LKW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00295 ^@ http://purl.uniprot.org/uniprot/A0LEA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/335543:SFUM_RS16490 ^@ http://purl.uniprot.org/uniprot/A0LN58 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/335543:SFUM_RS21680 ^@ http://purl.uniprot.org/uniprot/A0LJ68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS01690 ^@ http://purl.uniprot.org/uniprot/A0LF30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00675 ^@ http://purl.uniprot.org/uniprot/A0LEH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14455 ^@ http://purl.uniprot.org/uniprot/A0LM14 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS09910 ^@ http://purl.uniprot.org/uniprot/A0LJK2 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/335543:SFUM_RS12335 ^@ http://purl.uniprot.org/uniprot/A0LKW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS19145 ^@ http://purl.uniprot.org/uniprot/A0LPM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/335543:SFUM_RS18825 ^@ http://purl.uniprot.org/uniprot/A0LPF8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/335543:SFUM_RS05295 ^@ http://purl.uniprot.org/uniprot/A0LH11 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/335543:SFUM_RS16115 ^@ http://purl.uniprot.org/uniprot/A0LMY7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/335543:SFUM_RS07020 ^@ http://purl.uniprot.org/uniprot/A0LHY8 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/335543:SFUM_RS15565 ^@ http://purl.uniprot.org/uniprot/A0LMM5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/335543:SFUM_RS13150 ^@ http://purl.uniprot.org/uniprot/A0LLB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS05600 ^@ http://purl.uniprot.org/uniprot/A0LH69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS06030 ^@ http://purl.uniprot.org/uniprot/A0LHF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS06595 ^@ http://purl.uniprot.org/uniprot/A0LHQ3 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/335543:SFUM_RS02580 ^@ http://purl.uniprot.org/uniprot/A0LFK0 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/335543:SFUM_RS09895 ^@ http://purl.uniprot.org/uniprot/A0LJK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/335543:SFUM_RS11565 ^@ http://purl.uniprot.org/uniprot/A0LKG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13405 ^@ http://purl.uniprot.org/uniprot/A0LLG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/335543:SFUM_RS00305 ^@ http://purl.uniprot.org/uniprot/A0LEA8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS06185 ^@ http://purl.uniprot.org/uniprot/A0LHH6 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS03535 ^@ http://purl.uniprot.org/uniprot/A0LG33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS15450 ^@ http://purl.uniprot.org/uniprot/A0LMK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/335543:SFUM_RS13385 ^@ http://purl.uniprot.org/uniprot/A0LLF6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS11755 ^@ http://purl.uniprot.org/uniprot/A0LKK4 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/335543:SFUM_RS07245 ^@ http://purl.uniprot.org/uniprot/A0LI34 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/335543:SFUM_RS03350 ^@ http://purl.uniprot.org/uniprot/A0LFZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS22030 ^@ http://purl.uniprot.org/uniprot/A0LNG2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS03755 ^@ http://purl.uniprot.org/uniprot/A0LG69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS06760 ^@ http://purl.uniprot.org/uniprot/A0LHT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS15820 ^@ http://purl.uniprot.org/uniprot/A0LMS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS16705 ^@ http://purl.uniprot.org/uniprot/A0LNA1 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/335543:SFUM_RS10820 ^@ http://purl.uniprot.org/uniprot/A0LK22 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/335543:SFUM_RS20560 ^@ http://purl.uniprot.org/uniprot/A0LQF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS17925 ^@ http://purl.uniprot.org/uniprot/A0LNZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS08035 ^@ http://purl.uniprot.org/uniprot/A0LII6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/335543:SFUM_RS17375 ^@ http://purl.uniprot.org/uniprot/A0LNN5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Cell inner membrane|||Inhibited by the protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP), but not by valinomycin.|||Proton-coupled L-lactate specific transporter. http://togogenome.org/gene/335543:SFUM_RS08630 ^@ http://purl.uniprot.org/uniprot/A0LIV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/335543:SFUM_RS00130 ^@ http://purl.uniprot.org/uniprot/A0LE72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/335543:SFUM_RS21520 ^@ http://purl.uniprot.org/uniprot/A0LHS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/335543:SFUM_RS21600 ^@ http://purl.uniprot.org/uniprot/A0LIE3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/335543:SFUM_RS20555 ^@ http://purl.uniprot.org/uniprot/A0LQF7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS02750 ^@ http://purl.uniprot.org/uniprot/A0LFN0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/335543:SFUM_RS14105 ^@ http://purl.uniprot.org/uniprot/A0LLU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/335543:SFUM_RS04345 ^@ http://purl.uniprot.org/uniprot/A0LGI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14475 ^@ http://purl.uniprot.org/uniprot/A0LM16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/335543:SFUM_RS11245 ^@ http://purl.uniprot.org/uniprot/A0LKA4 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/335543:SFUM_RS13965 ^@ http://purl.uniprot.org/uniprot/A0LLS0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/335543:SFUM_RS01955 ^@ http://purl.uniprot.org/uniprot/A0LF82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14470 ^@ http://purl.uniprot.org/uniprot/A0LM15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/335543:SFUM_RS20275 ^@ http://purl.uniprot.org/uniprot/A0LQ97 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/335543:SFUM_RS20670 ^@ http://purl.uniprot.org/uniprot/A0LQH5 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/335543:SFUM_RS03660 ^@ http://purl.uniprot.org/uniprot/A0LG50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/335543:SFUM_RS04675 ^@ http://purl.uniprot.org/uniprot/A0LGP7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/335543:SFUM_RS12085 ^@ http://purl.uniprot.org/uniprot/A0LKR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS09665 ^@ http://purl.uniprot.org/uniprot/A0LJF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS12235 ^@ http://purl.uniprot.org/uniprot/A0LKU4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/335543:SFUM_RS04850 ^@ http://purl.uniprot.org/uniprot/A0LGS8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/335543:SFUM_RS08015 ^@ http://purl.uniprot.org/uniprot/A0LII2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/335543:SFUM_RS08125 ^@ http://purl.uniprot.org/uniprot/A0LIK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/335543:SFUM_RS15330 ^@ http://purl.uniprot.org/uniprot/A0LMH8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/335543:SFUM_RS07000 ^@ http://purl.uniprot.org/uniprot/A0LHY4 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/335543:SFUM_RS07350 ^@ http://purl.uniprot.org/uniprot/A0LI55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/335543:SFUM_RS08205 ^@ http://purl.uniprot.org/uniprot/A0LIM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS10120 ^@ http://purl.uniprot.org/uniprot/A0LJN9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/335543:SFUM_RS07085 ^@ http://purl.uniprot.org/uniprot/A0LI00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/335543:SFUM_RS08815 ^@ http://purl.uniprot.org/uniprot/A0LIZ1 ^@ Function|||Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/335543:SFUM_RS23475 ^@ http://purl.uniprot.org/uniprot/A0LHG9 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS08055 ^@ http://purl.uniprot.org/uniprot/A0LIJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/335543:SFUM_RS09775 ^@ http://purl.uniprot.org/uniprot/A0LJH5 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/335543:SFUM_RS06630 ^@ http://purl.uniprot.org/uniprot/A0LHR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/335543:SFUM_RS00940 ^@ http://purl.uniprot.org/uniprot/A0LEN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS07545 ^@ http://purl.uniprot.org/uniprot/A0LI93 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS10955 ^@ http://purl.uniprot.org/uniprot/A0LK49 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/335543:SFUM_RS16260 ^@ http://purl.uniprot.org/uniprot/A0LN15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14340 ^@ http://purl.uniprot.org/uniprot/A0LLZ2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS14170 ^@ http://purl.uniprot.org/uniprot/A0LLW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS08625 ^@ http://purl.uniprot.org/uniprot/A0LIV3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/335543:SFUM_RS16185 ^@ http://purl.uniprot.org/uniprot/A0LN01 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/335543:SFUM_RS03085 ^@ http://purl.uniprot.org/uniprot/A0LFU6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/335543:SFUM_RS18810 ^@ http://purl.uniprot.org/uniprot/A0LPF5 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/335543:SFUM_RS08470 ^@ http://purl.uniprot.org/uniprot/A0LIS1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/335543:SFUM_RS02675 ^@ http://purl.uniprot.org/uniprot/A0LFL7 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS19375 ^@ http://purl.uniprot.org/uniprot/A0LPR4 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/335543:SFUM_RS09220 ^@ http://purl.uniprot.org/uniprot/A0LJ69 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/335543:SFUM_RS16885 ^@ http://purl.uniprot.org/uniprot/A0LND6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/335543:SFUM_RS15595 ^@ http://purl.uniprot.org/uniprot/A0LMN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS15700 ^@ http://purl.uniprot.org/uniprot/A0LML0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/335543:SFUM_RS09045 ^@ http://purl.uniprot.org/uniprot/A0LJ36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11180 ^@ http://purl.uniprot.org/uniprot/A0LK92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14680 ^@ http://purl.uniprot.org/uniprot/A0LEI8 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/335543:SFUM_RS20185 ^@ http://purl.uniprot.org/uniprot/A0LQ79 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/335543:SFUM_RS11160 ^@ http://purl.uniprot.org/uniprot/A0LK87 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/335543:SFUM_RS00340 ^@ http://purl.uniprot.org/uniprot/A0LEB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS15750 ^@ http://purl.uniprot.org/uniprot/A0LMM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/335543:SFUM_RS20510 ^@ http://purl.uniprot.org/uniprot/A0LQE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/335543:SFUM_RS09040 ^@ http://purl.uniprot.org/uniprot/A0LJ35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/335543:SFUM_RS02140 ^@ http://purl.uniprot.org/uniprot/A0LFB7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS05450 ^@ http://purl.uniprot.org/uniprot/A0LH38 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/335543:SFUM_RS21460 ^@ http://purl.uniprot.org/uniprot/A0LH74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00010 ^@ http://purl.uniprot.org/uniprot/A0LE54 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/335543:SFUM_RS17955 ^@ http://purl.uniprot.org/uniprot/A0LNZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS15685 ^@ http://purl.uniprot.org/uniprot/A0LMK7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/335543:SFUM_RS15915 ^@ http://purl.uniprot.org/uniprot/A0LMU6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/335543:SFUM_RS01925 ^@ http://purl.uniprot.org/uniprot/A0LF76 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/335543:SFUM_RS13735 ^@ http://purl.uniprot.org/uniprot/A0LLM4 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/335543:SFUM_RS13585 ^@ http://purl.uniprot.org/uniprot/A0LLJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/335543:SFUM_RS09170 ^@ http://purl.uniprot.org/uniprot/A0LJ59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS16475 ^@ http://purl.uniprot.org/uniprot/A0LN55 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/335543:SFUM_RS07160 ^@ http://purl.uniprot.org/uniprot/A0LI16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS16820 ^@ http://purl.uniprot.org/uniprot/A0LNC4 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/335543:SFUM_RS01825 ^@ http://purl.uniprot.org/uniprot/A0LF56 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/335543:SFUM_RS11350 ^@ http://purl.uniprot.org/uniprot/A0LKC5 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/335543:SFUM_RS17900 ^@ http://purl.uniprot.org/uniprot/A0LNY5 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS07445 ^@ http://purl.uniprot.org/uniprot/A0LI73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/335543:SFUM_RS20880 ^@ http://purl.uniprot.org/uniprot/A0LQL7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS02470 ^@ http://purl.uniprot.org/uniprot/A0LFH9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/335543:SFUM_RS03205 ^@ http://purl.uniprot.org/uniprot/A0LFX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS20975 ^@ http://purl.uniprot.org/uniprot/A0LQN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS05900 ^@ http://purl.uniprot.org/uniprot/A0LHC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS02810 ^@ http://purl.uniprot.org/uniprot/A0LFP2 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/335543:SFUM_RS09420 ^@ http://purl.uniprot.org/uniprot/A0LJA7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/335543:SFUM_RS05715 ^@ http://purl.uniprot.org/uniprot/A0LH90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08860 ^@ http://purl.uniprot.org/uniprot/A0LJ00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS13830 ^@ http://purl.uniprot.org/uniprot/A0LLP4 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS08795 ^@ http://purl.uniprot.org/uniprot/A0LIY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/335543:SFUM_RS17060 ^@ http://purl.uniprot.org/uniprot/A0LNH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10875 ^@ http://purl.uniprot.org/uniprot/A0LK33 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/335543:SFUM_RS13740 ^@ http://purl.uniprot.org/uniprot/A0LLM5 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS13935 ^@ http://purl.uniprot.org/uniprot/A0LLR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/335543:SFUM_RS17385 ^@ http://purl.uniprot.org/uniprot/A0LNN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS01805 ^@ http://purl.uniprot.org/uniprot/A0LF52 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/335543:SFUM_RS14820 ^@ http://purl.uniprot.org/uniprot/A0LM81 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS02185 ^@ http://purl.uniprot.org/uniprot/A0LFC5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/335543:SFUM_RS14090 ^@ http://purl.uniprot.org/uniprot/A0LLU4 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/335543:SFUM_RS10975 ^@ http://purl.uniprot.org/uniprot/A0LK53 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/335543:SFUM_RS10530 ^@ http://purl.uniprot.org/uniprot/A0LJW5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell inner membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/335543:SFUM_RS06665 ^@ http://purl.uniprot.org/uniprot/A0LHR9 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/335543:SFUM_RS14880 ^@ http://purl.uniprot.org/uniprot/A0LM93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS01555 ^@ http://purl.uniprot.org/uniprot/A0LF03 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS14990 ^@ http://purl.uniprot.org/uniprot/A0LMB2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/335543:SFUM_RS13645 ^@ http://purl.uniprot.org/uniprot/A0LLK7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/335543:SFUM_RS01045 ^@ http://purl.uniprot.org/uniprot/A0LEQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS07155 ^@ http://purl.uniprot.org/uniprot/A0LI15 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/335543:SFUM_RS10290 ^@ http://purl.uniprot.org/uniprot/A0LJR8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/335543:SFUM_RS09485 ^@ http://purl.uniprot.org/uniprot/A0LJB9 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/335543:SFUM_RS15475 ^@ http://purl.uniprot.org/uniprot/A0LMK7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/335543:SFUM_RS20085 ^@ http://purl.uniprot.org/uniprot/A0LQ58 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the desulfoferrodoxin family.|||Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.|||Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS15540 ^@ http://purl.uniprot.org/uniprot/A0LMM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/335543:SFUM_RS13950 ^@ http://purl.uniprot.org/uniprot/A0LLR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS01055 ^@ http://purl.uniprot.org/uniprot/A0LEQ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS03490 ^@ http://purl.uniprot.org/uniprot/A0LG25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/335543:SFUM_RS15710 ^@ http://purl.uniprot.org/uniprot/A0LML2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS15210 ^@ http://purl.uniprot.org/uniprot/A0LMF6 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/335543:SFUM_RS00300 ^@ http://purl.uniprot.org/uniprot/A0LEA7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/335543:SFUM_RS12605 ^@ http://purl.uniprot.org/uniprot/A0LL15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS09210 ^@ http://purl.uniprot.org/uniprot/A0LJ67 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS10040 ^@ http://purl.uniprot.org/uniprot/A0LJM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||In the N-terminal section; belongs to the complex I 20 kDa subunit family.|||In the central section; belongs to the complex I 30 kDa subunit family.|||NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex (By similarity).|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS13940 ^@ http://purl.uniprot.org/uniprot/A0LLR5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/335543:SFUM_RS08045 ^@ http://purl.uniprot.org/uniprot/A0LIH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/335543:SFUM_RS03640 ^@ http://purl.uniprot.org/uniprot/A0LG46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/335543:SFUM_RS05735 ^@ http://purl.uniprot.org/uniprot/A0LH94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/335543:SFUM_RS12155 ^@ http://purl.uniprot.org/uniprot/A0LKS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS17205 ^@ http://purl.uniprot.org/uniprot/A0LNK1 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/335543:SFUM_RS15075 ^@ http://purl.uniprot.org/uniprot/A0LMB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/335543:SFUM_RS15760 ^@ http://purl.uniprot.org/uniprot/A0LMM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/335543:SFUM_RS03315 ^@ http://purl.uniprot.org/uniprot/A0LFZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS18890 ^@ http://purl.uniprot.org/uniprot/A0LPH0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved. http://togogenome.org/gene/335543:SFUM_RS16785 ^@ http://purl.uniprot.org/uniprot/A0LNB7 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/335543:SFUM_RS00240 ^@ http://purl.uniprot.org/uniprot/A0LE95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/335543:SFUM_RS15575 ^@ http://purl.uniprot.org/uniprot/A0LMM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS01100 ^@ http://purl.uniprot.org/uniprot/A0LER2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/335543:SFUM_RS13460 ^@ http://purl.uniprot.org/uniprot/A0LLH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/335543:SFUM_RS08680 ^@ http://purl.uniprot.org/uniprot/A0LIW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18090 ^@ http://purl.uniprot.org/uniprot/A0LP23 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/335543:SFUM_RS07610 ^@ http://purl.uniprot.org/uniprot/A0LIA5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS09205 ^@ http://purl.uniprot.org/uniprot/A0LJ66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/335543:SFUM_RS09345 ^@ http://purl.uniprot.org/uniprot/A0LJ92 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/335543:SFUM_RS10045 ^@ http://purl.uniprot.org/uniprot/A0LJM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS01095 ^@ http://purl.uniprot.org/uniprot/A0LER1 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/335543:SFUM_RS13035 ^@ http://purl.uniprot.org/uniprot/A0LL98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS02765 ^@ http://purl.uniprot.org/uniprot/A0LFN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS06820 ^@ http://purl.uniprot.org/uniprot/A0LHV0 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS10815 ^@ http://purl.uniprot.org/uniprot/A0LK21 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/335543:SFUM_RS02415 ^@ http://purl.uniprot.org/uniprot/A0LFG9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/335543:SFUM_RS20630 ^@ http://purl.uniprot.org/uniprot/A0LQG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS13410 ^@ http://purl.uniprot.org/uniprot/A0LLG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/335543:SFUM_RS11820 ^@ http://purl.uniprot.org/uniprot/A0LKL7 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/335543:SFUM_RS06675 ^@ http://purl.uniprot.org/uniprot/A0LHS1 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/335543:SFUM_RS12400 ^@ http://purl.uniprot.org/uniprot/A0LKX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS02615 ^@ http://purl.uniprot.org/uniprot/A0LFK7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/335543:SFUM_RS02205 ^@ http://purl.uniprot.org/uniprot/A0LFC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell inner membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/335543:SFUM_RS15670 ^@ http://purl.uniprot.org/uniprot/A0LMK4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/335543:SFUM_RS20140 ^@ http://purl.uniprot.org/uniprot/A0LQ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS20005 ^@ http://purl.uniprot.org/uniprot/A0LQ41 ^@ Cofactor|||Subunit ^@ Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS16200 ^@ http://purl.uniprot.org/uniprot/A0LN04 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS01725 ^@ http://purl.uniprot.org/uniprot/A0LF36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS22110 ^@ http://purl.uniprot.org/uniprot/A0LPD0 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/335543:SFUM_RS12030 ^@ http://purl.uniprot.org/uniprot/A0LKQ5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/335543:SFUM_RS01305 ^@ http://purl.uniprot.org/uniprot/A0LEV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS20685 ^@ http://purl.uniprot.org/uniprot/A0LQH8 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/335543:SFUM_RS17080 ^@ http://purl.uniprot.org/uniprot/A0LNH6 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/335543:SFUM_RS05040 ^@ http://purl.uniprot.org/uniprot/A0LGW4 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/335543:SFUM_RS13495 ^@ http://purl.uniprot.org/uniprot/A0LLH8 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/335543:SFUM_RS07900 ^@ http://purl.uniprot.org/uniprot/A0LIG1 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/335543:SFUM_RS06110 ^@ http://purl.uniprot.org/uniprot/A0LHG2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS15305 ^@ http://purl.uniprot.org/uniprot/A0LMH3 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/335543:SFUM_RS16265 ^@ http://purl.uniprot.org/uniprot/A0LN16 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS10900 ^@ http://purl.uniprot.org/uniprot/A0LK38 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/335543:SFUM_RS17920 ^@ http://purl.uniprot.org/uniprot/A0LNY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS20700 ^@ http://purl.uniprot.org/uniprot/A0LQI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13930 ^@ http://purl.uniprot.org/uniprot/A0LLR3 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/335543:SFUM_RS04845 ^@ http://purl.uniprot.org/uniprot/A0LGS7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/335543:SFUM_RS08100 ^@ http://purl.uniprot.org/uniprot/A0LIJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS10235 ^@ http://purl.uniprot.org/uniprot/A0LJQ8 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS13025 ^@ http://purl.uniprot.org/uniprot/A0LL96 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS08850 ^@ http://purl.uniprot.org/uniprot/A0LIZ8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/335543:SFUM_RS10180 ^@ http://purl.uniprot.org/uniprot/A0LJQ0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/335543:SFUM_RS18330 ^@ http://purl.uniprot.org/uniprot/A0LP67 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/335543:SFUM_RS17520 ^@ http://purl.uniprot.org/uniprot/A0LNR4 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/335543:SFUM_RS03510 ^@ http://purl.uniprot.org/uniprot/A0LG29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS11760 ^@ http://purl.uniprot.org/uniprot/A0LKK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08985 ^@ http://purl.uniprot.org/uniprot/A0LJ24 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/335543:SFUM_RS08285 ^@ http://purl.uniprot.org/uniprot/A0LIN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/335543:SFUM_RS18955 ^@ http://purl.uniprot.org/uniprot/A0LPI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS01355 ^@ http://purl.uniprot.org/uniprot/A0LEW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13985 ^@ http://purl.uniprot.org/uniprot/A0LLS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/335543:SFUM_RS08910 ^@ http://purl.uniprot.org/uniprot/A0LJ09 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/335543:SFUM_RS00160 ^@ http://purl.uniprot.org/uniprot/A0LE79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS11485 ^@ http://purl.uniprot.org/uniprot/A0LKE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS10200 ^@ http://purl.uniprot.org/uniprot/A0LJQ2 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/335543:SFUM_RS10785 ^@ http://purl.uniprot.org/uniprot/A0LK14 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS17635 ^@ http://purl.uniprot.org/uniprot/A0LNT5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/335543:SFUM_RS03775 ^@ http://purl.uniprot.org/uniprot/A0LG72 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/335543:SFUM_RS10735 ^@ http://purl.uniprot.org/uniprot/A0LK05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS02330 ^@ http://purl.uniprot.org/uniprot/A0LFF3 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/335543:SFUM_RS12355 ^@ http://purl.uniprot.org/uniprot/A0LKW7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/335543:SFUM_RS08505 ^@ http://purl.uniprot.org/uniprot/A0LIS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS03500 ^@ http://purl.uniprot.org/uniprot/A0LG27 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/335543:SFUM_RS16980 ^@ http://purl.uniprot.org/uniprot/A0LNF6 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/335543:SFUM_RS00790 ^@ http://purl.uniprot.org/uniprot/A0LEK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03965 ^@ http://purl.uniprot.org/uniprot/A0LGA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS06935 ^@ http://purl.uniprot.org/uniprot/A0LHX1 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/335543:SFUM_RS06460 ^@ http://purl.uniprot.org/uniprot/A0LHM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/335543:SFUM_RS14180 ^@ http://purl.uniprot.org/uniprot/A0LLW3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/335543:SFUM_RS19355 ^@ http://purl.uniprot.org/uniprot/A0LPR0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS01600 ^@ http://purl.uniprot.org/uniprot/A0LF13 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/335543:SFUM_RS00335 ^@ http://purl.uniprot.org/uniprot/A0LEB4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/335543:SFUM_RS14190 ^@ http://purl.uniprot.org/uniprot/A0LLW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/335543:SFUM_RS14795 ^@ http://purl.uniprot.org/uniprot/A0LM78 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/335543:SFUM_RS00350 ^@ http://purl.uniprot.org/uniprot/A0LEB7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/335543:SFUM_RS06625 ^@ http://purl.uniprot.org/uniprot/A0LHQ9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane http://togogenome.org/gene/335543:SFUM_RS17935 ^@ http://purl.uniprot.org/uniprot/A0LNZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/335543:SFUM_RS00680 ^@ http://purl.uniprot.org/uniprot/A0LEH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS11155 ^@ http://purl.uniprot.org/uniprot/A0LK86 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/335543:SFUM_RS04715 ^@ http://purl.uniprot.org/uniprot/A0LGQ5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS08810 ^@ http://purl.uniprot.org/uniprot/A0LIZ0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/335543:SFUM_RS02210 ^@ http://purl.uniprot.org/uniprot/A0LFD0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/335543:SFUM_RS20060 ^@ http://purl.uniprot.org/uniprot/A0LQ54 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/335543:SFUM_RS20710 ^@ http://purl.uniprot.org/uniprot/A0LQI3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/335543:SFUM_RS10960 ^@ http://purl.uniprot.org/uniprot/A0LK50 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/335543:SFUM_RS06310 ^@ http://purl.uniprot.org/uniprot/A0LHK1 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/335543:SFUM_RS18550 ^@ http://purl.uniprot.org/uniprot/A0LPA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS13535 ^@ http://purl.uniprot.org/uniprot/A0LLI6 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/335543:SFUM_RS01865 ^@ http://purl.uniprot.org/uniprot/A0LF64 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/335543:SFUM_RS21020 ^@ http://purl.uniprot.org/uniprot/A0LQP2 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/335543:SFUM_RS05995 ^@ http://purl.uniprot.org/uniprot/A0LHE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||In the N-terminal section; belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/335543:SFUM_RS18360 ^@ http://purl.uniprot.org/uniprot/A0LP73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00255 ^@ http://purl.uniprot.org/uniprot/A0LE98 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/335543:SFUM_RS04060 ^@ http://purl.uniprot.org/uniprot/A0LGC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00025 ^@ http://purl.uniprot.org/uniprot/A0LE55 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS06150 ^@ http://purl.uniprot.org/uniprot/A0LHH0 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS15310 ^@ http://purl.uniprot.org/uniprot/A0LMH4 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/335543:SFUM_RS20890 ^@ http://purl.uniprot.org/uniprot/A0LQL9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/335543:SFUM_RS20290 ^@ http://purl.uniprot.org/uniprot/A0LHF4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/335543:SFUM_RS14260 ^@ http://purl.uniprot.org/uniprot/A0LLX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS23325 ^@ http://purl.uniprot.org/uniprot/A0LK26 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/335543:SFUM_RS10150 ^@ http://purl.uniprot.org/uniprot/A0LJP5 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/335543:SFUM_RS21315 ^@ http://purl.uniprot.org/uniprot/A0LFW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10420 ^@ http://purl.uniprot.org/uniprot/A0LJU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00560 ^@ http://purl.uniprot.org/uniprot/A0LEF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/335543:SFUM_RS15870 ^@ http://purl.uniprot.org/uniprot/A0LMT6 ^@ Similarity ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. http://togogenome.org/gene/335543:SFUM_RS08335 ^@ http://purl.uniprot.org/uniprot/A0LIP7 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/335543:SFUM_RS10940 ^@ http://purl.uniprot.org/uniprot/A0LK46 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/335543:SFUM_RS02560 ^@ http://purl.uniprot.org/uniprot/A0LFJ5 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/335543:SFUM_RS00540 ^@ http://purl.uniprot.org/uniprot/A0LEF2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/335543:SFUM_RS14950 ^@ http://purl.uniprot.org/uniprot/A0LMA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/335543:SFUM_RS06350 ^@ http://purl.uniprot.org/uniprot/A0LHK8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS02840 ^@ http://purl.uniprot.org/uniprot/A0LFP8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/335543:SFUM_RS15755 ^@ http://purl.uniprot.org/uniprot/A0LMM1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/335543:SFUM_RS01605 ^@ http://purl.uniprot.org/uniprot/A0LF14 ^@ Similarity ^@ Belongs to the QNG1 protein family. http://togogenome.org/gene/335543:SFUM_RS01025 ^@ http://purl.uniprot.org/uniprot/A0LEP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS12240 ^@ http://purl.uniprot.org/uniprot/A0LKU5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/335543:SFUM_RS00520 ^@ http://purl.uniprot.org/uniprot/A0LEE9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/335543:SFUM_RS16555 ^@ http://purl.uniprot.org/uniprot/A0LN72 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS14160 ^@ http://purl.uniprot.org/uniprot/A0LLV9 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/335543:SFUM_RS08130 ^@ http://purl.uniprot.org/uniprot/A0LIK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/335543:SFUM_RS04680 ^@ http://purl.uniprot.org/uniprot/A0LGP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11720 ^@ http://purl.uniprot.org/uniprot/A0LKJ4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/335543:SFUM_RS02950 ^@ http://purl.uniprot.org/uniprot/A0LFR9 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS03980 ^@ http://purl.uniprot.org/uniprot/A0LGB0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS01975 ^@ http://purl.uniprot.org/uniprot/A0LF86 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/335543:SFUM_RS03430 ^@ http://purl.uniprot.org/uniprot/A0LG13 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/335543:SFUM_RS09275 ^@ http://purl.uniprot.org/uniprot/A0LJ79 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS15315 ^@ http://purl.uniprot.org/uniprot/A0LMH5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit.|||Periplasm http://togogenome.org/gene/335543:SFUM_RS03025 ^@ http://purl.uniprot.org/uniprot/A0LFT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS18515 ^@ http://purl.uniprot.org/uniprot/A0LPA3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS03875 ^@ http://purl.uniprot.org/uniprot/A0LG90 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/335543:SFUM_RS18180 ^@ http://purl.uniprot.org/uniprot/A0LP38 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS09035 ^@ http://purl.uniprot.org/uniprot/A0LJ34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS10015 ^@ http://purl.uniprot.org/uniprot/A0LJM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS11240 ^@ http://purl.uniprot.org/uniprot/A0LKA3 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/335543:SFUM_RS17120 ^@ http://purl.uniprot.org/uniprot/A0LNI4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/335543:SFUM_RS09165 ^@ http://purl.uniprot.org/uniprot/A0LJ58 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/335543:SFUM_RS13705 ^@ http://purl.uniprot.org/uniprot/A0LLL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/335543:SFUM_RS10920 ^@ http://purl.uniprot.org/uniprot/A0LK42 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/335543:SFUM_RS20695 ^@ http://purl.uniprot.org/uniprot/A0LQI0 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/335543:SFUM_RS17820 ^@ http://purl.uniprot.org/uniprot/A0LNX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/335543:SFUM_RS21895 ^@ http://purl.uniprot.org/uniprot/A0LLS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08750 ^@ http://purl.uniprot.org/uniprot/A0LIX8 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/335543:SFUM_RS17115 ^@ http://purl.uniprot.org/uniprot/A0LNI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/335543:SFUM_RS06580 ^@ http://purl.uniprot.org/uniprot/A0LHQ0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS01035 ^@ http://purl.uniprot.org/uniprot/A0LEP9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS18365 ^@ http://purl.uniprot.org/uniprot/A0LP74 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/335543:SFUM_RS10985 ^@ http://purl.uniprot.org/uniprot/A0LK54 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS01200 ^@ http://purl.uniprot.org/uniprot/A0LET3 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/335543:SFUM_RS10345 ^@ http://purl.uniprot.org/uniprot/A0LJS9 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/335543:SFUM_RS07515 ^@ http://purl.uniprot.org/uniprot/A0LI87 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS07730 ^@ http://purl.uniprot.org/uniprot/A0LID0 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/335543:SFUM_RS15155 ^@ http://purl.uniprot.org/uniprot/A0LME5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18695 ^@ http://purl.uniprot.org/uniprot/A0LPD7 ^@ Function ^@ Catalyzes the synthesis of GMP from XMP. http://togogenome.org/gene/335543:SFUM_RS22235 ^@ http://purl.uniprot.org/uniprot/A0LQM5 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/335543:SFUM_RS12320 ^@ http://purl.uniprot.org/uniprot/A0LKW0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS13515 ^@ http://purl.uniprot.org/uniprot/A0LLI2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/335543:SFUM_RS13680 ^@ http://purl.uniprot.org/uniprot/A0LLL3 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/335543:SFUM_RS14135 ^@ http://purl.uniprot.org/uniprot/A0LLV4 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/335543:SFUM_RS07150 ^@ http://purl.uniprot.org/uniprot/A0LI14 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/335543:SFUM_RS20690 ^@ http://purl.uniprot.org/uniprot/A0LQH9 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/335543:SFUM_RS11850 ^@ http://purl.uniprot.org/uniprot/A0LKM1 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/335543:SFUM_RS10245 ^@ http://purl.uniprot.org/uniprot/A0LJR0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/335543:SFUM_RS06915 ^@ http://purl.uniprot.org/uniprot/A0LHW7 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/335543:SFUM_RS12670 ^@ http://purl.uniprot.org/uniprot/A0LL28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS12170 ^@ http://purl.uniprot.org/uniprot/A0LKT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS21130 ^@ http://purl.uniprot.org/uniprot/A0LQR3 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/335543:SFUM_RS04670 ^@ http://purl.uniprot.org/uniprot/A0LGP5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS19225 ^@ http://purl.uniprot.org/uniprot/A0LPN7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS03215 ^@ http://purl.uniprot.org/uniprot/A0LFX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS11630 ^@ http://purl.uniprot.org/uniprot/A0LKH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00055 ^@ http://purl.uniprot.org/uniprot/A0LE61 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/335543:SFUM_RS15680 ^@ http://purl.uniprot.org/uniprot/A0LMK6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS23925 ^@ http://purl.uniprot.org/uniprot/A0LJ18 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/335543:SFUM_RS09150 ^@ http://purl.uniprot.org/uniprot/A0LJ55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/335543:SFUM_RS18850 ^@ http://purl.uniprot.org/uniprot/A0LPG3 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/335543:SFUM_RS15000 ^@ http://purl.uniprot.org/uniprot/A0LMB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/335543:SFUM_RS07060 ^@ http://purl.uniprot.org/uniprot/A0LHZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/335543:SFUM_RS19270 ^@ http://purl.uniprot.org/uniprot/A0LPP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18085 ^@ http://purl.uniprot.org/uniprot/A0LP22 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/335543:SFUM_RS03345 ^@ http://purl.uniprot.org/uniprot/A0LFZ7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS14480 ^@ http://purl.uniprot.org/uniprot/A0LM17 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/335543:SFUM_RS02915 ^@ http://purl.uniprot.org/uniprot/A0LFR2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/335543:SFUM_RS05370 ^@ http://purl.uniprot.org/uniprot/A0LH25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/335543:SFUM_RS07555 ^@ http://purl.uniprot.org/uniprot/A0LI95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS15030 ^@ http://purl.uniprot.org/uniprot/A0LMC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/335543:SFUM_RS00405 ^@ http://purl.uniprot.org/uniprot/A0LEC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/335543:SFUM_RS14670 ^@ http://purl.uniprot.org/uniprot/A0LM56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/335543:SFUM_RS06270 ^@ http://purl.uniprot.org/uniprot/A0LHJ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||May bind 1 zinc ion per subunit.|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/335543:SFUM_RS20995 ^@ http://purl.uniprot.org/uniprot/A0LQN7 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/335543:SFUM_RS03495 ^@ http://purl.uniprot.org/uniprot/A0LG26 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/335543:SFUM_RS07360 ^@ http://purl.uniprot.org/uniprot/A0LI57 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS02515 ^@ http://purl.uniprot.org/uniprot/A0LFI6 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/335543:SFUM_RS15925 ^@ http://purl.uniprot.org/uniprot/A0LMU8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/335543:SFUM_RS13075 ^@ http://purl.uniprot.org/uniprot/A0LLA6 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/335543:SFUM_RS19500 ^@ http://purl.uniprot.org/uniprot/A0LPT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/335543:SFUM_RS13975 ^@ http://purl.uniprot.org/uniprot/A0LLS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00895 ^@ http://purl.uniprot.org/uniprot/A0LEM2 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/335543:SFUM_RS01185 ^@ http://purl.uniprot.org/uniprot/A0LES9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS15220 ^@ http://purl.uniprot.org/uniprot/A0LMF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/335543:SFUM_RS14010 ^@ http://purl.uniprot.org/uniprot/A0LLT0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/335543:SFUM_RS00525 ^@ http://purl.uniprot.org/uniprot/A0LEF0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/335543:SFUM_RS10665 ^@ http://purl.uniprot.org/uniprot/A0LJZ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS08175 ^@ http://purl.uniprot.org/uniprot/A0LIL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/335543:SFUM_RS03800 ^@ http://purl.uniprot.org/uniprot/A0LG76 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/335543:SFUM_RS20765 ^@ http://purl.uniprot.org/uniprot/A0LQJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS15025 ^@ http://purl.uniprot.org/uniprot/A0LMB9 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/335543:SFUM_RS09325 ^@ http://purl.uniprot.org/uniprot/A0LJ87 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS08380 ^@ http://purl.uniprot.org/uniprot/A0LIQ4 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/335543:SFUM_RS03925 ^@ http://purl.uniprot.org/uniprot/A0LG99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS02635 ^@ http://purl.uniprot.org/uniprot/A0LFL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS05730 ^@ http://purl.uniprot.org/uniprot/A0LH93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07990 ^@ http://purl.uniprot.org/uniprot/A0LIH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/335543:SFUM_RS08005 ^@ http://purl.uniprot.org/uniprot/A0LII0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/335543:SFUM_RS08120 ^@ http://purl.uniprot.org/uniprot/A0LIK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/335543:SFUM_RS17670 ^@ http://purl.uniprot.org/uniprot/A0LNU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS17795 ^@ http://purl.uniprot.org/uniprot/A0LNW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS18370 ^@ http://purl.uniprot.org/uniprot/A0LP75 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-72 and Arg-75) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/335543:SFUM_RS00320 ^@ http://purl.uniprot.org/uniprot/A0LEB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS03655 ^@ http://purl.uniprot.org/uniprot/A0LG49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS05470 ^@ http://purl.uniprot.org/uniprot/A0LH42 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS06395 ^@ http://purl.uniprot.org/uniprot/A0LHL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/335543:SFUM_RS11710 ^@ http://purl.uniprot.org/uniprot/A0LKJ2 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/335543:SFUM_RS18050 ^@ http://purl.uniprot.org/uniprot/A0LP15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/335543:SFUM_RS20835 ^@ http://purl.uniprot.org/uniprot/A0LQK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS01505 ^@ http://purl.uniprot.org/uniprot/A0LEZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00475 ^@ http://purl.uniprot.org/uniprot/A0LEE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS18780 ^@ http://purl.uniprot.org/uniprot/A0LPE9 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/335543:SFUM_RS05590 ^@ http://purl.uniprot.org/uniprot/A0LH67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS00050 ^@ http://purl.uniprot.org/uniprot/A0LE60 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS02380 ^@ http://purl.uniprot.org/uniprot/A0LFG2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/335543:SFUM_RS01880 ^@ http://purl.uniprot.org/uniprot/A0LF67 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/335543:SFUM_RS20680 ^@ http://purl.uniprot.org/uniprot/A0LQH7 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/335543:SFUM_RS15955 ^@ http://purl.uniprot.org/uniprot/A0LMV5 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS12490 ^@ http://purl.uniprot.org/uniprot/A0LKZ3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/335543:SFUM_RS04535 ^@ http://purl.uniprot.org/uniprot/A0LGL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS06705 ^@ http://purl.uniprot.org/uniprot/A0LHS6 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS06255 ^@ http://purl.uniprot.org/uniprot/A0LHJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS06290 ^@ http://purl.uniprot.org/uniprot/A0LHJ7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/335543:SFUM_RS05280 ^@ http://purl.uniprot.org/uniprot/A0LH08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/335543:SFUM_RS00450 ^@ http://purl.uniprot.org/uniprot/A0LED7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS05540 ^@ http://purl.uniprot.org/uniprot/A0LH56 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/335543:SFUM_RS08945 ^@ http://purl.uniprot.org/uniprot/A0LJ16 ^@ Caution|||Similarity ^@ Arg-61 is present instead of the conserved Lys which is expected to be an active site residue. The same site-directed mutant in B.cereus has no activity; therefore this protein is probably inactive.|||Belongs to the HAD-like hydrolase superfamily. PhnX family. http://togogenome.org/gene/335543:SFUM_RS04340 ^@ http://purl.uniprot.org/uniprot/A0LGI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18225 ^@ http://purl.uniprot.org/uniprot/A0LP48 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/335543:SFUM_RS00135 ^@ http://purl.uniprot.org/uniprot/A0LE73 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/335543:SFUM_RS20325 ^@ http://purl.uniprot.org/uniprot/A0LQA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS12135 ^@ http://purl.uniprot.org/uniprot/A0LKS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/335543:SFUM_RS09920 ^@ http://purl.uniprot.org/uniprot/A0LJK4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS18765 ^@ http://purl.uniprot.org/uniprot/A0LPE6 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/335543:SFUM_RS04010 ^@ http://purl.uniprot.org/uniprot/A0LGB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/335543:SFUM_RS17295 ^@ http://purl.uniprot.org/uniprot/A0LNM0 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/335543:SFUM_RS04860 ^@ http://purl.uniprot.org/uniprot/A0LGT0 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/335543:SFUM_RS01385 ^@ http://purl.uniprot.org/uniprot/A0LEW9 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/335543:SFUM_RS00535 ^@ http://purl.uniprot.org/uniprot/A0LEF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/335543:SFUM_RS15785 ^@ http://purl.uniprot.org/uniprot/A0LMM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS18935 ^@ http://purl.uniprot.org/uniprot/A0LPH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS02965 ^@ http://purl.uniprot.org/uniprot/A0LFS3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/335543:SFUM_RS00645 ^@ http://purl.uniprot.org/uniprot/A0LEH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/335543:SFUM_RS05285 ^@ http://purl.uniprot.org/uniprot/A0LH09 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/335543:SFUM_RS10880 ^@ http://purl.uniprot.org/uniprot/A0LK34 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/335543:SFUM_RS10930 ^@ http://purl.uniprot.org/uniprot/A0LK44 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/335543:SFUM_RS23530 ^@ http://purl.uniprot.org/uniprot/A0LJR6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS15660 ^@ http://purl.uniprot.org/uniprot/A0LMK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/335543:SFUM_RS06560 ^@ http://purl.uniprot.org/uniprot/A0LHP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/335543:SFUM_RS12055 ^@ http://purl.uniprot.org/uniprot/A0LKR0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/335543:SFUM_RS18760 ^@ http://purl.uniprot.org/uniprot/A0LPE5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/335543:SFUM_RS17745 ^@ http://purl.uniprot.org/uniprot/A0LNV7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/335543:SFUM_RS03275 ^@ http://purl.uniprot.org/uniprot/A0LFY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS11045 ^@ http://purl.uniprot.org/uniprot/A0LK64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/335543:SFUM_RS20150 ^@ http://purl.uniprot.org/uniprot/A0LQ71 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/335543:SFUM_RS08040 ^@ http://purl.uniprot.org/uniprot/A0LII7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/335543:SFUM_RS13425 ^@ http://purl.uniprot.org/uniprot/A0LLG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/335543:SFUM_RS10705 ^@ http://purl.uniprot.org/uniprot/A0LJZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/335543:SFUM_RS22125 ^@ http://purl.uniprot.org/uniprot/A0LPF4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS17490 ^@ http://purl.uniprot.org/uniprot/A0LNQ8 ^@ Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer. http://togogenome.org/gene/335543:SFUM_RS15805 ^@ http://purl.uniprot.org/uniprot/A0LMN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS17350 ^@ http://purl.uniprot.org/uniprot/A0LNN1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/335543:SFUM_RS03575 ^@ http://purl.uniprot.org/uniprot/A0LG39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/335543:SFUM_RS17410 ^@ http://purl.uniprot.org/uniprot/A0LNP1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS02480 ^@ http://purl.uniprot.org/uniprot/A0LFI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/335543:SFUM_RS19110 ^@ http://purl.uniprot.org/uniprot/A0LPL5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/335543:SFUM_RS01105 ^@ http://purl.uniprot.org/uniprot/A0LER3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/335543:SFUM_RS15470 ^@ http://purl.uniprot.org/uniprot/A0LMK6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS15740 ^@ http://purl.uniprot.org/uniprot/A0LML8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/335543:SFUM_RS10025 ^@ http://purl.uniprot.org/uniprot/A0LJM3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS15340 ^@ http://purl.uniprot.org/uniprot/A0LMI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS14130 ^@ http://purl.uniprot.org/uniprot/A0LLV3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/335543:SFUM_RS00855 ^@ http://purl.uniprot.org/uniprot/A0LEL4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/335543:SFUM_RS10010 ^@ http://purl.uniprot.org/uniprot/A0LJM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11120 ^@ http://purl.uniprot.org/uniprot/A0LK79 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS10005 ^@ http://purl.uniprot.org/uniprot/A0LJL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS01960 ^@ http://purl.uniprot.org/uniprot/A0LF83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS04720 ^@ http://purl.uniprot.org/uniprot/A0LGQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS06415 ^@ http://purl.uniprot.org/uniprot/A0LHM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/335543:SFUM_RS14860 ^@ http://purl.uniprot.org/uniprot/A0LM89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS21000 ^@ http://purl.uniprot.org/uniprot/A0LQN8 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/335543:SFUM_RS01495 ^@ http://purl.uniprot.org/uniprot/A0LEZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS20980 ^@ http://purl.uniprot.org/uniprot/A0LQN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS01815 ^@ http://purl.uniprot.org/uniprot/A0LF54 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS00275 ^@ http://purl.uniprot.org/uniprot/A0LEA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/335543:SFUM_RS07635 ^@ http://purl.uniprot.org/uniprot/A0LIB0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/335543:SFUM_RS19190 ^@ http://purl.uniprot.org/uniprot/A0LPN0 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS08060 ^@ http://purl.uniprot.org/uniprot/A0LIJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS11060 ^@ http://purl.uniprot.org/uniprot/A0LK67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS19995 ^@ http://purl.uniprot.org/uniprot/A0LQ39 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/335543:SFUM_RS08010 ^@ http://purl.uniprot.org/uniprot/A0LII1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/335543:SFUM_RS00190 ^@ http://purl.uniprot.org/uniprot/A0LE85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/335543:SFUM_RS11210 ^@ http://purl.uniprot.org/uniprot/A0LK97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/335543:SFUM_RS09625 ^@ http://purl.uniprot.org/uniprot/A0LJE6 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/335543:SFUM_RS10620 ^@ http://purl.uniprot.org/uniprot/A0LJY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11495 ^@ http://purl.uniprot.org/uniprot/A0LKF0 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/335543:SFUM_RS00765 ^@ http://purl.uniprot.org/uniprot/A0LEJ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/335543:SFUM_RS09845 ^@ http://purl.uniprot.org/uniprot/A0LJJ0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/335543:SFUM_RS20915 ^@ http://purl.uniprot.org/uniprot/A0LQM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/335543:SFUM_RS06435 ^@ http://purl.uniprot.org/uniprot/A0LHM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/335543:SFUM_RS08900 ^@ http://purl.uniprot.org/uniprot/A0LJ07 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS11940 ^@ http://purl.uniprot.org/uniprot/A0LKN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS04095 ^@ http://purl.uniprot.org/uniprot/A0LGD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10020 ^@ http://purl.uniprot.org/uniprot/A0LJM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS00325 ^@ http://purl.uniprot.org/uniprot/A0LEB2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/335543:SFUM_RS15090 ^@ http://purl.uniprot.org/uniprot/A0LMD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08030 ^@ http://purl.uniprot.org/uniprot/A0LII5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/335543:SFUM_RS13070 ^@ http://purl.uniprot.org/uniprot/A0LLA5 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/335543:SFUM_RS19055 ^@ http://purl.uniprot.org/uniprot/A0LPK4 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/335543:SFUM_RS08095 ^@ http://purl.uniprot.org/uniprot/A0LIJ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/335543:SFUM_RS06025 ^@ http://purl.uniprot.org/uniprot/A0LHE9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS14025 ^@ http://purl.uniprot.org/uniprot/A0LLT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS08875 ^@ http://purl.uniprot.org/uniprot/A0LJ03 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/335543:SFUM_RS12880 ^@ http://purl.uniprot.org/uniprot/A0LL70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/335543:SFUM_RS10565 ^@ http://purl.uniprot.org/uniprot/A0LJX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03235 ^@ http://purl.uniprot.org/uniprot/A0LFX7 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/335543:SFUM_RS00395 ^@ http://purl.uniprot.org/uniprot/A0LEC6 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/335543:SFUM_RS16880 ^@ http://purl.uniprot.org/uniprot/A0LND5 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/335543:SFUM_RS03240 ^@ http://purl.uniprot.org/uniprot/A0LFX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS02170 ^@ http://purl.uniprot.org/uniprot/A0LFC2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS17885 ^@ http://purl.uniprot.org/uniprot/A0LNY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/335543:SFUM_RS14080 ^@ http://purl.uniprot.org/uniprot/A0LLU3 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/335543:SFUM_RS03730 ^@ http://purl.uniprot.org/uniprot/A0LG64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. http://togogenome.org/gene/335543:SFUM_RS06060 ^@ http://purl.uniprot.org/uniprot/A0LHF4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/335543:SFUM_RS05595 ^@ http://purl.uniprot.org/uniprot/A0LH68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS03780 ^@ http://purl.uniprot.org/uniprot/A0LG73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS16580 ^@ http://purl.uniprot.org/uniprot/A0LN77 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/335543:SFUM_RS05175 ^@ http://purl.uniprot.org/uniprot/A0LGY7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/335543:SFUM_RS12760 ^@ http://purl.uniprot.org/uniprot/A0LL48 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS08160 ^@ http://purl.uniprot.org/uniprot/A0LIL2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/335543:SFUM_RS10350 ^@ http://purl.uniprot.org/uniprot/A0LJT0 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/335543:SFUM_RS17450 ^@ http://purl.uniprot.org/uniprot/A0LNQ0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS09970 ^@ http://purl.uniprot.org/uniprot/A0LJL3 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/335543:SFUM_RS07485 ^@ http://purl.uniprot.org/uniprot/A0LI80 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/335543:SFUM_RS01175 ^@ http://purl.uniprot.org/uniprot/A0LES7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/335543:SFUM_RS23960 ^@ http://purl.uniprot.org/uniprot/A0LM03 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/335543:SFUM_RS15920 ^@ http://purl.uniprot.org/uniprot/A0LMU7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/335543:SFUM_RS04810 ^@ http://purl.uniprot.org/uniprot/A0LGS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/335543:SFUM_RS04025 ^@ http://purl.uniprot.org/uniprot/A0LGC0 ^@ Caution|||Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS19185 ^@ http://purl.uniprot.org/uniprot/A0LPM9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS13960 ^@ http://purl.uniprot.org/uniprot/A0LLR9 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the ApbE family.|||Heterodimer of a large and a small subunit.|||Magnesium. Can also use manganese. http://togogenome.org/gene/335543:SFUM_RS23605 ^@ http://purl.uniprot.org/uniprot/A0LNR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03395 ^@ http://purl.uniprot.org/uniprot/A0LG07 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/335543:SFUM_RS03765 ^@ http://purl.uniprot.org/uniprot/A0LG71 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane http://togogenome.org/gene/335543:SFUM_RS20250 ^@ http://purl.uniprot.org/uniprot/A0LQ92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS12465 ^@ http://purl.uniprot.org/uniprot/A0LKY9 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/335543:SFUM_RS18845 ^@ http://purl.uniprot.org/uniprot/A0LPG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS08755 ^@ http://purl.uniprot.org/uniprot/A0LIX9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/335543:SFUM_RS12140 ^@ http://purl.uniprot.org/uniprot/A0LKS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/335543:SFUM_RS15145 ^@ http://purl.uniprot.org/uniprot/A0LME3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/335543:SFUM_RS14100 ^@ http://purl.uniprot.org/uniprot/A0LLU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS16775 ^@ http://purl.uniprot.org/uniprot/A0LNB5 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/335543:SFUM_RS01330 ^@ http://purl.uniprot.org/uniprot/A0LEV9 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/335543:SFUM_RS02830 ^@ http://purl.uniprot.org/uniprot/A0LFP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS08460 ^@ http://purl.uniprot.org/uniprot/A0LIR9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS17320 ^@ http://purl.uniprot.org/uniprot/A0LNM5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/335543:SFUM_RS06940 ^@ http://purl.uniprot.org/uniprot/A0LHX2 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/335543:SFUM_RS09000 ^@ http://purl.uniprot.org/uniprot/A0LJ27 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/335543:SFUM_RS07015 ^@ http://purl.uniprot.org/uniprot/A0LHY7 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/335543:SFUM_RS01750 ^@ http://purl.uniprot.org/uniprot/A0LF41 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/335543:SFUM_RS07920 ^@ http://purl.uniprot.org/uniprot/A0LIG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS00150 ^@ http://purl.uniprot.org/uniprot/A0LE76 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS17005 ^@ http://purl.uniprot.org/uniprot/A0LNG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS02290 ^@ http://purl.uniprot.org/uniprot/A0LFE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS19405 ^@ http://purl.uniprot.org/uniprot/A0LPR9 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/335543:SFUM_RS08075 ^@ http://purl.uniprot.org/uniprot/A0LIJ4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/335543:SFUM_RS13330 ^@ http://purl.uniprot.org/uniprot/A0LLF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11215 ^@ http://purl.uniprot.org/uniprot/A0LK98 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS18790 ^@ http://purl.uniprot.org/uniprot/A0LPF0 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/335543:SFUM_RS15490 ^@ http://purl.uniprot.org/uniprot/A0LML0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/335543:SFUM_RS10325 ^@ http://purl.uniprot.org/uniprot/A0LJS5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved Asp active site. http://togogenome.org/gene/335543:SFUM_RS12420 ^@ http://purl.uniprot.org/uniprot/A0LKX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13470 ^@ http://purl.uniprot.org/uniprot/A0LLH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/335543:SFUM_RS04645 ^@ http://purl.uniprot.org/uniprot/A0LGP0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/335543:SFUM_RS06790 ^@ http://purl.uniprot.org/uniprot/A0LHU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS10660 ^@ http://purl.uniprot.org/uniprot/A0LJZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/335543:SFUM_RS18290 ^@ http://purl.uniprot.org/uniprot/A0LP60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS12405 ^@ http://purl.uniprot.org/uniprot/A0LKX7 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/335543:SFUM_RS13475 ^@ http://purl.uniprot.org/uniprot/A0LLH4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/335543:SFUM_RS09565 ^@ http://purl.uniprot.org/uniprot/A0LJD4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/335543:SFUM_RS08235 ^@ http://purl.uniprot.org/uniprot/A0LIM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/335543:SFUM_RS16545 ^@ http://purl.uniprot.org/uniprot/A0LN70 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/335543:SFUM_RS01785 ^@ http://purl.uniprot.org/uniprot/A0LF48 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/335543:SFUM_RS19380 ^@ http://purl.uniprot.org/uniprot/A0LPR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/335543:SFUM_RS15345 ^@ http://purl.uniprot.org/uniprot/A0LMI1 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/335543:SFUM_RS02195 ^@ http://purl.uniprot.org/uniprot/A0LFC7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/335543:SFUM_RS05160 ^@ http://purl.uniprot.org/uniprot/A0LGY4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/335543:SFUM_RS21655 ^@ http://purl.uniprot.org/uniprot/A0LIT7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS10675 ^@ http://purl.uniprot.org/uniprot/A0LJZ3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS13480 ^@ http://purl.uniprot.org/uniprot/A0LLH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/335543:SFUM_RS11785 ^@ http://purl.uniprot.org/uniprot/A0LKL0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/335543:SFUM_RS15525 ^@ http://purl.uniprot.org/uniprot/A0LML7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/335543:SFUM_RS08105 ^@ http://purl.uniprot.org/uniprot/A0LIK0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/335543:SFUM_RS15535 ^@ http://purl.uniprot.org/uniprot/A0LML9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/335543:SFUM_RS02450 ^@ http://purl.uniprot.org/uniprot/A0LFH6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/335543:SFUM_RS08690 ^@ http://purl.uniprot.org/uniprot/A0LIW6 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/335543:SFUM_RS09155 ^@ http://purl.uniprot.org/uniprot/A0LJ56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/335543:SFUM_RS16495 ^@ http://purl.uniprot.org/uniprot/A0LN59 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/335543:SFUM_RS19935 ^@ http://purl.uniprot.org/uniprot/A0LQ26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS06690 ^@ http://purl.uniprot.org/uniprot/A0LHS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||Nucleus http://togogenome.org/gene/335543:SFUM_RS14790 ^@ http://purl.uniprot.org/uniprot/A0LM77 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/335543:SFUM_RS03515 ^@ http://purl.uniprot.org/uniprot/A0LG30 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/335543:SFUM_RS07175 ^@ http://purl.uniprot.org/uniprot/A0LI19 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS03920 ^@ http://purl.uniprot.org/uniprot/A0LG98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS10770 ^@ http://purl.uniprot.org/uniprot/A0LK12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/335543:SFUM_RS00965 ^@ http://purl.uniprot.org/uniprot/A0LEN5 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/335543:SFUM_RS19360 ^@ http://purl.uniprot.org/uniprot/A0LPR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07180 ^@ http://purl.uniprot.org/uniprot/A0LI20 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/335543:SFUM_RS18155 ^@ http://purl.uniprot.org/uniprot/A0LP35 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/335543:SFUM_RS03940 ^@ http://purl.uniprot.org/uniprot/A0LGA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane http://togogenome.org/gene/335543:SFUM_RS20805 ^@ http://purl.uniprot.org/uniprot/A0LQK3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/335543:SFUM_RS04395 ^@ http://purl.uniprot.org/uniprot/A0LGJ1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/335543:SFUM_RS06605 ^@ http://purl.uniprot.org/uniprot/A0LHQ5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/335543:SFUM_RS17000 ^@ http://purl.uniprot.org/uniprot/A0LNG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13315 ^@ http://purl.uniprot.org/uniprot/A0LLE7 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/335543:SFUM_RS03160 ^@ http://purl.uniprot.org/uniprot/A0LFW2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/335543:SFUM_RS08025 ^@ http://purl.uniprot.org/uniprot/A0LII4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/335543:SFUM_RS09425 ^@ http://purl.uniprot.org/uniprot/A0LJA8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS02190 ^@ http://purl.uniprot.org/uniprot/A0LFC6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/335543:SFUM_RS08155 ^@ http://purl.uniprot.org/uniprot/A0LIL1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS07390 ^@ http://purl.uniprot.org/uniprot/A0LI63 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/335543:SFUM_RS07140 ^@ http://purl.uniprot.org/uniprot/A0LI12 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/335543:SFUM_RS07010 ^@ http://purl.uniprot.org/uniprot/A0LHY6 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm3 family. http://togogenome.org/gene/335543:SFUM_RS07370 ^@ http://purl.uniprot.org/uniprot/A0LI59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/335543:SFUM_RS08800 ^@ http://purl.uniprot.org/uniprot/A0LIY8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/335543:SFUM_RS01145 ^@ http://purl.uniprot.org/uniprot/A0LES1 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/335543:SFUM_RS19010 ^@ http://purl.uniprot.org/uniprot/A0LPJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS13825 ^@ http://purl.uniprot.org/uniprot/A0LLP2 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/335543:SFUM_RS12885 ^@ http://purl.uniprot.org/uniprot/A0LL71 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS09365 ^@ http://purl.uniprot.org/uniprot/A0LJ96 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/335543:SFUM_RS09915 ^@ http://purl.uniprot.org/uniprot/A0LJK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/335543:SFUM_RS15040 ^@ http://purl.uniprot.org/uniprot/A0LMC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS18475 ^@ http://purl.uniprot.org/uniprot/A0LP96 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/335543:SFUM_RS05190 ^@ http://purl.uniprot.org/uniprot/A0LGZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS05050 ^@ http://purl.uniprot.org/uniprot/A0LGW6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/335543:SFUM_RS08185 ^@ http://purl.uniprot.org/uniprot/A0LIL7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/335543:SFUM_RS05505 ^@ http://purl.uniprot.org/uniprot/A0LH50 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/335543:SFUM_RS12375 ^@ http://purl.uniprot.org/uniprot/A0LKX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS17815 ^@ http://purl.uniprot.org/uniprot/A0LNW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS22135 ^@ http://purl.uniprot.org/uniprot/A0LPI6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/335543:SFUM_RS02000 ^@ http://purl.uniprot.org/uniprot/A0LF91 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/335543:SFUM_RS18325 ^@ http://purl.uniprot.org/uniprot/A0LP66 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/335543:SFUM_RS20045 ^@ http://purl.uniprot.org/uniprot/A0LQ51 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/335543:SFUM_RS17515 ^@ http://purl.uniprot.org/uniprot/A0LNR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/335543:SFUM_RS07855 ^@ http://purl.uniprot.org/uniprot/A0LIF0 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/335543:SFUM_RS15530 ^@ http://purl.uniprot.org/uniprot/A0LML8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/335543:SFUM_RS13945 ^@ http://purl.uniprot.org/uniprot/A0LLR6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/335543:SFUM_RS08310 ^@ http://purl.uniprot.org/uniprot/A0LIP3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS06455 ^@ http://purl.uniprot.org/uniprot/A0LHM8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/335543:SFUM_RS03325 ^@ http://purl.uniprot.org/uniprot/A0LFZ3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS23280 ^@ http://purl.uniprot.org/uniprot/A0LHG4 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS20395 ^@ http://purl.uniprot.org/uniprot/A0LQC2 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS00900 ^@ http://purl.uniprot.org/uniprot/A0LEM3 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/335543:SFUM_RS05275 ^@ http://purl.uniprot.org/uniprot/A0LH07 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/335543:SFUM_RS07675 ^@ http://purl.uniprot.org/uniprot/A0LIB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13395 ^@ http://purl.uniprot.org/uniprot/A0LLF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/335543:SFUM_RS16925 ^@ http://purl.uniprot.org/uniprot/A0LNE5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/335543:SFUM_RS09195 ^@ http://purl.uniprot.org/uniprot/A0LJ64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS17495 ^@ http://purl.uniprot.org/uniprot/A0LNQ9 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/335543:SFUM_RS15405 ^@ http://purl.uniprot.org/uniprot/A0LMJ3 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS17550 ^@ http://purl.uniprot.org/uniprot/A0LNS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS05705 ^@ http://purl.uniprot.org/uniprot/A0LH88 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/335543:SFUM_RS17360 ^@ http://purl.uniprot.org/uniprot/A0LNN3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS11800 ^@ http://purl.uniprot.org/uniprot/A0LKL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS16220 ^@ http://purl.uniprot.org/uniprot/A0LN07 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS11715 ^@ http://purl.uniprot.org/uniprot/A0LKJ3 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/335543:SFUM_RS10710 ^@ http://purl.uniprot.org/uniprot/A0LK00 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/335543:SFUM_RS15510 ^@ http://purl.uniprot.org/uniprot/A0LML4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/335543:SFUM_RS11900 ^@ http://purl.uniprot.org/uniprot/A0LKN1 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/335543:SFUM_RS09190 ^@ http://purl.uniprot.org/uniprot/A0LJ63 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/335543:SFUM_RS07615 ^@ http://purl.uniprot.org/uniprot/A0LIA6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/335543:SFUM_RS18900 ^@ http://purl.uniprot.org/uniprot/A0LPH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/335543:SFUM_RS04185 ^@ http://purl.uniprot.org/uniprot/A0LGF2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS17445 ^@ http://purl.uniprot.org/uniprot/A0LNP9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/335543:SFUM_RS11380 ^@ http://purl.uniprot.org/uniprot/A0LKD0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS03570 ^@ http://purl.uniprot.org/uniprot/A0LG38 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/335543:SFUM_RS16215 ^@ http://purl.uniprot.org/uniprot/A0LN06 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/335543:SFUM_RS02955 ^@ http://purl.uniprot.org/uniprot/A0LFS0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/335543:SFUM_RS15460 ^@ http://purl.uniprot.org/uniprot/A0LMK4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/335543:SFUM_RS03255 ^@ http://purl.uniprot.org/uniprot/A0LFY1 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/335543:SFUM_RS07335 ^@ http://purl.uniprot.org/uniprot/A0LI52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS03745 ^@ http://purl.uniprot.org/uniprot/A0LG67 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/335543:SFUM_RS01065 ^@ http://purl.uniprot.org/uniprot/A0LEQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS08210 ^@ http://purl.uniprot.org/uniprot/A0LIM1 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/335543:SFUM_RS08615 ^@ http://purl.uniprot.org/uniprot/A0LIV1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS07300 ^@ http://purl.uniprot.org/uniprot/A0LI45 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/335543:SFUM_RS07630 ^@ http://purl.uniprot.org/uniprot/A0LIA9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/335543:SFUM_RS09135 ^@ http://purl.uniprot.org/uniprot/A0LJ52 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/335543:SFUM_RS01830 ^@ http://purl.uniprot.org/uniprot/A0LF57 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/335543:SFUM_RS00980 ^@ http://purl.uniprot.org/uniprot/A0LEN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03595 ^@ http://purl.uniprot.org/uniprot/A0LG43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS22105 ^@ http://purl.uniprot.org/uniprot/A0LP84 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/335543:SFUM_RS16035 ^@ http://purl.uniprot.org/uniprot/A0LMX1 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/335543:SFUM_RS18510 ^@ http://purl.uniprot.org/uniprot/A0LPA2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/335543:SFUM_RS12610 ^@ http://purl.uniprot.org/uniprot/A0LL16 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/335543:SFUM_RS06280 ^@ http://purl.uniprot.org/uniprot/A0LHJ5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/335543:SFUM_RS19540 ^@ http://purl.uniprot.org/uniprot/A0LPU6 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/335543:SFUM_RS13020 ^@ http://purl.uniprot.org/uniprot/A0LL95 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/335543:SFUM_RS07120 ^@ http://purl.uniprot.org/uniprot/A0LI08 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/335543:SFUM_RS05385 ^@ http://purl.uniprot.org/uniprot/A0LH28 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/335543:SFUM_RS16365 ^@ http://purl.uniprot.org/uniprot/A0LN36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS12160 ^@ http://purl.uniprot.org/uniprot/A0LKS9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/335543:SFUM_RS07080 ^@ http://purl.uniprot.org/uniprot/A0LHZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/335543:SFUM_RS01795 ^@ http://purl.uniprot.org/uniprot/A0LF50 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS07660 ^@ http://purl.uniprot.org/uniprot/A0LIB6 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/335543:SFUM_RS14435 ^@ http://purl.uniprot.org/uniprot/A0LM10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS15335 ^@ http://purl.uniprot.org/uniprot/A0LMH9 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/335543:SFUM_RS19115 ^@ http://purl.uniprot.org/uniprot/A0LPL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/335543:SFUM_RS14570 ^@ http://purl.uniprot.org/uniprot/A0LM35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS06300 ^@ http://purl.uniprot.org/uniprot/A0LHJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/335543:SFUM_RS09060 ^@ http://purl.uniprot.org/uniprot/A0LJ39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14845 ^@ http://purl.uniprot.org/uniprot/A0LM85 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/335543:SFUM_RS00235 ^@ http://purl.uniprot.org/uniprot/A0LE94 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/335543:SFUM_RS07185 ^@ http://purl.uniprot.org/uniprot/A0LI21 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/335543:SFUM_RS20240 ^@ http://purl.uniprot.org/uniprot/A0LQ90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS19915 ^@ http://purl.uniprot.org/uniprot/A0LQ21 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/335543:SFUM_RS05185 ^@ http://purl.uniprot.org/uniprot/A0LGY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS09620 ^@ http://purl.uniprot.org/uniprot/A0LJE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11205 ^@ http://purl.uniprot.org/uniprot/A0LK96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/335543:SFUM_RS17355 ^@ http://purl.uniprot.org/uniprot/A0LNN2 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/335543:SFUM_RS17190 ^@ http://purl.uniprot.org/uniprot/A0LNJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS15125 ^@ http://purl.uniprot.org/uniprot/A0LMD8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/335543:SFUM_RS14575 ^@ http://purl.uniprot.org/uniprot/A0LM36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.|||Cell inner membrane|||Homodimer.|||Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. http://togogenome.org/gene/335543:SFUM_RS13420 ^@ http://purl.uniprot.org/uniprot/A0LLG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00640 ^@ http://purl.uniprot.org/uniprot/A0LEH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/335543:SFUM_RS04815 ^@ http://purl.uniprot.org/uniprot/A0LGS2 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/335543:SFUM_RS05260 ^@ http://purl.uniprot.org/uniprot/A0LH04 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/335543:SFUM_RS08620 ^@ http://purl.uniprot.org/uniprot/A0LIV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS08110 ^@ http://purl.uniprot.org/uniprot/A0LIK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS00650 ^@ http://purl.uniprot.org/uniprot/A0LEH3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/335543:SFUM_RS01590 ^@ http://purl.uniprot.org/uniprot/A0LF11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS15895 ^@ http://purl.uniprot.org/uniprot/A0LMU1 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/335543:SFUM_RS13000 ^@ http://purl.uniprot.org/uniprot/A0LL91 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/335543:SFUM_RS13015 ^@ http://purl.uniprot.org/uniprot/A0LL94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS09265 ^@ http://purl.uniprot.org/uniprot/A0LJ77 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS03050 ^@ http://purl.uniprot.org/uniprot/A0LFU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS08115 ^@ http://purl.uniprot.org/uniprot/A0LIK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/335543:SFUM_RS02925 ^@ http://purl.uniprot.org/uniprot/A0LFR4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS07380 ^@ http://purl.uniprot.org/uniprot/A0LI61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS14350 ^@ http://purl.uniprot.org/uniprot/A0LLZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/335543:SFUM_RS09005 ^@ http://purl.uniprot.org/uniprot/A0LJ28 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/335543:SFUM_RS00045 ^@ http://purl.uniprot.org/uniprot/A0LE59 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS11220 ^@ http://purl.uniprot.org/uniprot/A0LK99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS18120 ^@ http://purl.uniprot.org/uniprot/A0LP28 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/335543:SFUM_RS08275 ^@ http://purl.uniprot.org/uniprot/A0LIN6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/335543:SFUM_RS05695 ^@ http://purl.uniprot.org/uniprot/A0LH86 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/335543:SFUM_RS20960 ^@ http://purl.uniprot.org/uniprot/A0LQN0 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/335543:SFUM_RS07130 ^@ http://purl.uniprot.org/uniprot/A0LI10 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS05420 ^@ http://purl.uniprot.org/uniprot/A0LH34 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS19015 ^@ http://purl.uniprot.org/uniprot/A0LPJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS11805 ^@ http://purl.uniprot.org/uniprot/A0LKL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS06250 ^@ http://purl.uniprot.org/uniprot/A0LHI9 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/335543:SFUM_RS16020 ^@ http://purl.uniprot.org/uniprot/A0LMW8 ^@ Similarity ^@ Belongs to the GPAT/DAPAT family. http://togogenome.org/gene/335543:SFUM_RS05330 ^@ http://purl.uniprot.org/uniprot/A0LH17 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/335543:SFUM_RS10910 ^@ http://purl.uniprot.org/uniprot/A0LK40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS03300 ^@ http://purl.uniprot.org/uniprot/A0LFY8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS10885 ^@ http://purl.uniprot.org/uniprot/A0LK35 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/335543:SFUM_RS07145 ^@ http://purl.uniprot.org/uniprot/A0LI13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/335543:SFUM_RS02960 ^@ http://purl.uniprot.org/uniprot/A0LFS1 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/335543:SFUM_RS03360 ^@ http://purl.uniprot.org/uniprot/A0LG00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS18500 ^@ http://purl.uniprot.org/uniprot/A0LPA0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/335543:SFUM_RS01460 ^@ http://purl.uniprot.org/uniprot/A0LEY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS02845 ^@ http://purl.uniprot.org/uniprot/A0LFP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS16920 ^@ http://purl.uniprot.org/uniprot/A0LNE4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/335543:SFUM_RS01370 ^@ http://purl.uniprot.org/uniprot/A0LEW7 ^@ Cofactor|||Similarity ^@ Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/335543:SFUM_RS04545 ^@ http://purl.uniprot.org/uniprot/A0LGM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS04260 ^@ http://purl.uniprot.org/uniprot/A0LGG6 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS03635 ^@ http://purl.uniprot.org/uniprot/A0LG45 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/335543:SFUM_RS14070 ^@ http://purl.uniprot.org/uniprot/A0LLU1 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS16360 ^@ http://purl.uniprot.org/uniprot/A0LN35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS15290 ^@ http://purl.uniprot.org/uniprot/A0LMH0 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS09660 ^@ http://purl.uniprot.org/uniprot/A0LJF2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/335543:SFUM_RS02360 ^@ http://purl.uniprot.org/uniprot/A0LFF8 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. Catalyzes the reduction of oxaloacetate more efficiently than the oxidation of malate.|||Homodimer.|||Substrate inhibition is observed at high concentrations of oxaloacetate. http://togogenome.org/gene/335543:SFUM_RS18775 ^@ http://purl.uniprot.org/uniprot/A0LPE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/335543:SFUM_RS02685 ^@ http://purl.uniprot.org/uniprot/A0LFM0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/335543:SFUM_RS20245 ^@ http://purl.uniprot.org/uniprot/A0LQ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS15800 ^@ http://purl.uniprot.org/uniprot/A0LMS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS21870 ^@ http://purl.uniprot.org/uniprot/A0LLH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/335543:SFUM_RS13065 ^@ http://purl.uniprot.org/uniprot/A0LLA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS17160 ^@ http://purl.uniprot.org/uniprot/A0LNJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS17050 ^@ http://purl.uniprot.org/uniprot/A0LNH0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS03665 ^@ http://purl.uniprot.org/uniprot/A0LG51 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/335543:SFUM_RS08090 ^@ http://purl.uniprot.org/uniprot/A0LIJ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS08725 ^@ http://purl.uniprot.org/uniprot/A0LIX2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS19675 ^@ http://purl.uniprot.org/uniprot/A0LPX3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS19085 ^@ http://purl.uniprot.org/uniprot/A0LPL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HisA/HisF family.|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/335543:SFUM_RS18075 ^@ http://purl.uniprot.org/uniprot/A0LP20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14055 ^@ http://purl.uniprot.org/uniprot/A0LLT8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/335543:SFUM_RS20235 ^@ http://purl.uniprot.org/uniprot/A0LQ89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS13375 ^@ http://purl.uniprot.org/uniprot/A0LLF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/335543:SFUM_RS04315 ^@ http://purl.uniprot.org/uniprot/A0LGH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS14300 ^@ http://purl.uniprot.org/uniprot/A0LLY5 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/335543:SFUM_RS09375 ^@ http://purl.uniprot.org/uniprot/A0LJ98 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/335543:SFUM_RS15035 ^@ http://purl.uniprot.org/uniprot/A0LMC1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. PhnX family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/335543:SFUM_RS15500 ^@ http://purl.uniprot.org/uniprot/A0LML2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS14730 ^@ http://purl.uniprot.org/uniprot/A0LM65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11130 ^@ http://purl.uniprot.org/uniprot/A0LK81 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/335543:SFUM_RS15735 ^@ http://purl.uniprot.org/uniprot/A0LML7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/335543:SFUM_RS17890 ^@ http://purl.uniprot.org/uniprot/A0LNY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS19385 ^@ http://purl.uniprot.org/uniprot/A0LPR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/335543:SFUM_RS11085 ^@ http://purl.uniprot.org/uniprot/A0LK72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07395 ^@ http://purl.uniprot.org/uniprot/A0LI64 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/335543:SFUM_RS02045 ^@ http://purl.uniprot.org/uniprot/A0LFA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00330 ^@ http://purl.uniprot.org/uniprot/A0LEB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS17565 ^@ http://purl.uniprot.org/uniprot/A0LNS3 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/335543:SFUM_RS18520 ^@ http://purl.uniprot.org/uniprot/A0LPA4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS02060 ^@ http://purl.uniprot.org/uniprot/A0LFA3 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/335543:SFUM_RS01005 ^@ http://purl.uniprot.org/uniprot/A0LEP3 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/335543:SFUM_RS13060 ^@ http://purl.uniprot.org/uniprot/A0LLA3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS15615 ^@ http://purl.uniprot.org/uniprot/A0LMJ3 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS15720 ^@ http://purl.uniprot.org/uniprot/A0LML4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/335543:SFUM_RS08700 ^@ http://purl.uniprot.org/uniprot/A0LIW8 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/335543:SFUM_RS06335 ^@ http://purl.uniprot.org/uniprot/A0LHK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS11405 ^@ http://purl.uniprot.org/uniprot/A0LKD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS04460 ^@ http://purl.uniprot.org/uniprot/A0LGK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08255 ^@ http://purl.uniprot.org/uniprot/A0LIN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/335543:SFUM_RS07055 ^@ http://purl.uniprot.org/uniprot/A0LHZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/335543:SFUM_RS23735 ^@ http://purl.uniprot.org/uniprot/A0LHP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11955 ^@ http://purl.uniprot.org/uniprot/A0LKP2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/335543:SFUM_RS10170 ^@ http://purl.uniprot.org/uniprot/A0LJP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/335543:SFUM_RS08065 ^@ http://purl.uniprot.org/uniprot/A0LIJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/335543:SFUM_RS02220 ^@ http://purl.uniprot.org/uniprot/A0LFD2 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/335543:SFUM_RS07645 ^@ http://purl.uniprot.org/uniprot/A0LIB2 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/335543:SFUM_RS08530 ^@ http://purl.uniprot.org/uniprot/A0LIT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS02160 ^@ http://purl.uniprot.org/uniprot/A0LFC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS07305 ^@ http://purl.uniprot.org/uniprot/A0LI46 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/335543:SFUM_RS06405 ^@ http://purl.uniprot.org/uniprot/A0LHL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/335543:SFUM_RS14240 ^@ http://purl.uniprot.org/uniprot/A0LLX4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/335543:SFUM_RS08520 ^@ http://purl.uniprot.org/uniprot/A0LIT0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS01935 ^@ http://purl.uniprot.org/uniprot/A0LF78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS01080 ^@ http://purl.uniprot.org/uniprot/A0LEQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS18270 ^@ http://purl.uniprot.org/uniprot/A0LP57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS07550 ^@ http://purl.uniprot.org/uniprot/A0LI94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS02570 ^@ http://purl.uniprot.org/uniprot/A0LFJ8 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/335543:SFUM_RS06680 ^@ http://purl.uniprot.org/uniprot/A0LHS2 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/335543:SFUM_RS01010 ^@ http://purl.uniprot.org/uniprot/A0LEP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS07945 ^@ http://purl.uniprot.org/uniprot/A0LIG9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/335543:SFUM_RS06745 ^@ http://purl.uniprot.org/uniprot/A0LHT3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/335543:SFUM_RS06360 ^@ http://purl.uniprot.org/uniprot/A0LHL0 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/335543:SFUM_RS02275 ^@ http://purl.uniprot.org/uniprot/A0LFE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07650 ^@ http://purl.uniprot.org/uniprot/A0LIB3 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/335543:SFUM_RS07720 ^@ http://purl.uniprot.org/uniprot/A0LIC8 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/335543:SFUM_RS17400 ^@ http://purl.uniprot.org/uniprot/A0LNN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS02590 ^@ http://purl.uniprot.org/uniprot/A0LFK2 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/335543:SFUM_RS17845 ^@ http://purl.uniprot.org/uniprot/A0LNX4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/335543:SFUM_RS07885 ^@ http://purl.uniprot.org/uniprot/A0LIF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS08250 ^@ http://purl.uniprot.org/uniprot/A0LIN1 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/335543:SFUM_RS11475 ^@ http://purl.uniprot.org/uniprot/A0LKE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS00550 ^@ http://purl.uniprot.org/uniprot/A0LEF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS14625 ^@ http://purl.uniprot.org/uniprot/A0LM47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/335543:SFUM_RS13570 ^@ http://purl.uniprot.org/uniprot/A0LLJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS23575 ^@ http://purl.uniprot.org/uniprot/A0LLY4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/335543:SFUM_RS08080 ^@ http://purl.uniprot.org/uniprot/A0LIJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/335543:SFUM_RS08930 ^@ http://purl.uniprot.org/uniprot/A0LJ13 ^@ Function|||Similarity ^@ Belongs to the OMP decarboxylase family.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). http://togogenome.org/gene/335543:SFUM_RS06295 ^@ http://purl.uniprot.org/uniprot/A0LHJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS13445 ^@ http://purl.uniprot.org/uniprot/A0LLG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/335543:SFUM_RS03835 ^@ http://purl.uniprot.org/uniprot/A0LG82 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/335543:SFUM_RS21830 ^@ http://purl.uniprot.org/uniprot/A0LL14 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS01050 ^@ http://purl.uniprot.org/uniprot/A0LEQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/335543:SFUM_RS01870 ^@ http://purl.uniprot.org/uniprot/A0LF65 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/335543:SFUM_RS12855 ^@ http://purl.uniprot.org/uniprot/A0LL65 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS19485 ^@ http://purl.uniprot.org/uniprot/A0LPT5 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/335543:SFUM_RS00410 ^@ http://purl.uniprot.org/uniprot/A0LEC9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/335543:SFUM_RS05635 ^@ http://purl.uniprot.org/uniprot/A0LH76 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS03455 ^@ http://purl.uniprot.org/uniprot/A0LG20 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 63 family. http://togogenome.org/gene/335543:SFUM_RS10100 ^@ http://purl.uniprot.org/uniprot/A0LJN5 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/335543:SFUM_RS00345 ^@ http://purl.uniprot.org/uniprot/A0LEB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS08140 ^@ http://purl.uniprot.org/uniprot/A0LIK8 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS10265 ^@ http://purl.uniprot.org/uniprot/A0LJR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS07560 ^@ http://purl.uniprot.org/uniprot/A0LI96 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS10155 ^@ http://purl.uniprot.org/uniprot/A0LJP6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/335543:SFUM_RS16625 ^@ http://purl.uniprot.org/uniprot/A0LN86 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/335543:SFUM_RS10135 ^@ http://purl.uniprot.org/uniprot/A0LJP2 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/335543:SFUM_RS07420 ^@ http://purl.uniprot.org/uniprot/A0LI69 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/335543:SFUM_RS10950 ^@ http://purl.uniprot.org/uniprot/A0LK48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS18600 ^@ http://purl.uniprot.org/uniprot/A0LPB9 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/335543:SFUM_RS00145 ^@ http://purl.uniprot.org/uniprot/A0LE75 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/335543:SFUM_RS07225 ^@ http://purl.uniprot.org/uniprot/A0LI30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS16970 ^@ http://purl.uniprot.org/uniprot/A0LNF4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/335543:SFUM_RS19410 ^@ http://purl.uniprot.org/uniprot/A0LPS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/335543:SFUM_RS18830 ^@ http://purl.uniprot.org/uniprot/A0LPF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS00605 ^@ http://purl.uniprot.org/uniprot/A0LEG4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/335543:SFUM_RS08760 ^@ http://purl.uniprot.org/uniprot/A0LIY0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/335543:SFUM_RS05895 ^@ http://purl.uniprot.org/uniprot/A0LHC1 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS01060 ^@ http://purl.uniprot.org/uniprot/A0LEQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS17905 ^@ http://purl.uniprot.org/uniprot/A0LNY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/335543:SFUM_RS11450 ^@ http://purl.uniprot.org/uniprot/A0LKE3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/335543:SFUM_RS19390 ^@ http://purl.uniprot.org/uniprot/A0LPR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/335543:SFUM_RS15590 ^@ http://purl.uniprot.org/uniprot/A0LMS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS04330 ^@ http://purl.uniprot.org/uniprot/A0LGH8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS14115 ^@ http://purl.uniprot.org/uniprot/A0LLU9 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS11570 ^@ http://purl.uniprot.org/uniprot/A0LKG5 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS01000 ^@ http://purl.uniprot.org/uniprot/A0LEP2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/335543:SFUM_RS02895 ^@ http://purl.uniprot.org/uniprot/A0LFQ8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS19510 ^@ http://purl.uniprot.org/uniprot/A0LPU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/335543:SFUM_RS20775 ^@ http://purl.uniprot.org/uniprot/A0LQJ7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/335543:SFUM_RS07210 ^@ http://purl.uniprot.org/uniprot/A0LI27 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/335543:SFUM_RS07405 ^@ http://purl.uniprot.org/uniprot/A0LI66 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/335543:SFUM_RS11030 ^@ http://purl.uniprot.org/uniprot/A0LK61 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/335543:SFUM_RS01640 ^@ http://purl.uniprot.org/uniprot/A0LF21 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/335543:SFUM_RS08170 ^@ http://purl.uniprot.org/uniprot/A0LIL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/335543:SFUM_RS09610 ^@ http://purl.uniprot.org/uniprot/A0LJE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07105 ^@ http://purl.uniprot.org/uniprot/A0LI05 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/335543:SFUM_RS02425 ^@ http://purl.uniprot.org/uniprot/A0LFH1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/335543:SFUM_RS08475 ^@ http://purl.uniprot.org/uniprot/A0LIS2 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/335543:SFUM_RS01485 ^@ http://purl.uniprot.org/uniprot/A0LEY9 ^@ Function ^@ Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). http://togogenome.org/gene/335543:SFUM_RS15655 ^@ http://purl.uniprot.org/uniprot/A0LMK1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/335543:SFUM_RS11780 ^@ http://purl.uniprot.org/uniprot/A0LKK9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/335543:SFUM_RS01980 ^@ http://purl.uniprot.org/uniprot/A0LF87 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/335543:SFUM_RS15745 ^@ http://purl.uniprot.org/uniprot/A0LML9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/335543:SFUM_RS10670 ^@ http://purl.uniprot.org/uniprot/A0LJZ2 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS23390 ^@ http://purl.uniprot.org/uniprot/A0LNC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10830 ^@ http://purl.uniprot.org/uniprot/A0LK24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS06325 ^@ http://purl.uniprot.org/uniprot/A0LHK3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/335543:SFUM_RS08975 ^@ http://purl.uniprot.org/uniprot/A0LJ22 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/335543:SFUM_RS07760 ^@ http://purl.uniprot.org/uniprot/A0LID6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS08070 ^@ http://purl.uniprot.org/uniprot/A0LIJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/335543:SFUM_RS16050 ^@ http://purl.uniprot.org/uniprot/A0LMX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS01930 ^@ http://purl.uniprot.org/uniprot/A0LF77 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/335543:SFUM_RS05525 ^@ http://purl.uniprot.org/uniprot/A0LH54 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS09075 ^@ http://purl.uniprot.org/uniprot/A0LJ41 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/335543:SFUM_RS02335 ^@ http://purl.uniprot.org/uniprot/A0LFF4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/335543:SFUM_RS14590 ^@ http://purl.uniprot.org/uniprot/A0LM40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS11635 ^@ http://purl.uniprot.org/uniprot/A0LKH7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS06400 ^@ http://purl.uniprot.org/uniprot/A0LHL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/335543:SFUM_RS16710 ^@ http://purl.uniprot.org/uniprot/A0LNA2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/335543:SFUM_RS12300 ^@ http://purl.uniprot.org/uniprot/A0LKV7 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS16680 ^@ http://purl.uniprot.org/uniprot/A0LN97 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS07330 ^@ http://purl.uniprot.org/uniprot/A0LI51 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/335543:SFUM_RS12695 ^@ http://purl.uniprot.org/uniprot/A0LL34 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/335543:SFUM_RS20195 ^@ http://purl.uniprot.org/uniprot/A0LQ81 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS03400 ^@ http://purl.uniprot.org/uniprot/A0LG08 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/335543:SFUM_RS04275 ^@ http://purl.uniprot.org/uniprot/A0LGG9 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/335543:SFUM_RS14280 ^@ http://purl.uniprot.org/uniprot/A0LLY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS11825 ^@ http://purl.uniprot.org/uniprot/A0LKL8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS21640 ^@ http://purl.uniprot.org/uniprot/A0LIR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS18920 ^@ http://purl.uniprot.org/uniprot/A0LPH6 ^@ Similarity ^@ Belongs to the bacterial secretin family. GSP D subfamily. http://togogenome.org/gene/335543:SFUM_RS00735 ^@ http://purl.uniprot.org/uniprot/A0LEJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS02910 ^@ http://purl.uniprot.org/uniprot/A0LFR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/335543:SFUM_RS16660 ^@ http://purl.uniprot.org/uniprot/A0LN93 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/335543:SFUM_RS15775 ^@ http://purl.uniprot.org/uniprot/A0LMM5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/335543:SFUM_RS20905 ^@ http://purl.uniprot.org/uniprot/A0LQM2 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/335543:SFUM_RS06615 ^@ http://purl.uniprot.org/uniprot/A0LHQ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS16945 ^@ http://purl.uniprot.org/uniprot/A0LNE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS08150 ^@ http://purl.uniprot.org/uniprot/A0LIL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/335543:SFUM_RS18685 ^@ http://purl.uniprot.org/uniprot/A0LPD5 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/335543:SFUM_RS16025 ^@ http://purl.uniprot.org/uniprot/A0LMW9 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/335543:SFUM_RS12905 ^@ http://purl.uniprot.org/uniprot/A0LL75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS20270 ^@ http://purl.uniprot.org/uniprot/A0LQ96 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/335543:SFUM_RS17070 ^@ http://purl.uniprot.org/uniprot/A0LNH4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS00225 ^@ http://purl.uniprot.org/uniprot/A0LE92 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/335543:SFUM_RS04865 ^@ http://purl.uniprot.org/uniprot/A0LGT1 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/335543:SFUM_RS00060 ^@ http://purl.uniprot.org/uniprot/A0LE62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS03075 ^@ http://purl.uniprot.org/uniprot/A0LFU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS01765 ^@ http://purl.uniprot.org/uniprot/A0LF44 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/335543:SFUM_RS14980 ^@ http://purl.uniprot.org/uniprot/A0LMB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS10035 ^@ http://purl.uniprot.org/uniprot/A0LJM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/335543:SFUM_RS10890 ^@ http://purl.uniprot.org/uniprot/A0LK36 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/335543:SFUM_RS00360 ^@ http://purl.uniprot.org/uniprot/A0LEB9 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/335543:SFUM_RS13990 ^@ http://purl.uniprot.org/uniprot/A0LLS5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/335543:SFUM_RS15835 ^@ http://purl.uniprot.org/uniprot/A0LMS9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/335543:SFUM_RS13400 ^@ http://purl.uniprot.org/uniprot/A0LLF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/335543:SFUM_RS17810 ^@ http://purl.uniprot.org/uniprot/A0LNW8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/335543:SFUM_RS16250 ^@ http://purl.uniprot.org/uniprot/A0LN13 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/335543:SFUM_RS04245 ^@ http://purl.uniprot.org/uniprot/A0LGG3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/335543:SFUM_RS17650 ^@ http://purl.uniprot.org/uniprot/A0LNT8 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/335543:SFUM_RS18960 ^@ http://purl.uniprot.org/uniprot/A0LPI4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/335543:SFUM_RS16540 ^@ http://purl.uniprot.org/uniprot/A0LN68 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/335543:SFUM_RS16635 ^@ http://purl.uniprot.org/uniprot/A0LN88 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/335543:SFUM_RS06660 ^@ http://purl.uniprot.org/uniprot/A0LHR8 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/335543:SFUM_RS12435 ^@ http://purl.uniprot.org/uniprot/A0LKY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/335543:SFUM_RS16620 ^@ http://purl.uniprot.org/uniprot/A0LN85 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/335543:SFUM_RS16465 ^@ http://purl.uniprot.org/uniprot/A0LN53 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/335543:SFUM_RS21765 ^@ http://purl.uniprot.org/uniprot/A0LKB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS19870 ^@ http://purl.uniprot.org/uniprot/A0LQ12 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/335543:SFUM_RS15545 ^@ http://purl.uniprot.org/uniprot/A0LMM1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/335543:SFUM_RS16355 ^@ http://purl.uniprot.org/uniprot/A0LN34 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/335543:SFUM_RS04390 ^@ http://purl.uniprot.org/uniprot/A0LGJ0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/335543:SFUM_RS02180 ^@ http://purl.uniprot.org/uniprot/A0LFC4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/335543:SFUM_RS11690 ^@ http://purl.uniprot.org/uniprot/A0LKI8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/335543:SFUM_RS07765 ^@ http://purl.uniprot.org/uniprot/A0LID7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18255 ^@ http://purl.uniprot.org/uniprot/A0LP54 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/335543:SFUM_RS03505 ^@ http://purl.uniprot.org/uniprot/A0LG28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS08820 ^@ http://purl.uniprot.org/uniprot/A0LIZ2 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/335543:SFUM_RS12650 ^@ http://purl.uniprot.org/uniprot/A0LL24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/335543:SFUM_RS13530 ^@ http://purl.uniprot.org/uniprot/A0LLI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate. http://togogenome.org/gene/335543:SFUM_RS05375 ^@ http://purl.uniprot.org/uniprot/A0LH26 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/335543:SFUM_RS01110 ^@ http://purl.uniprot.org/uniprot/A0LER4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/335543:SFUM_RS13925 ^@ http://purl.uniprot.org/uniprot/A0LLR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS20115 ^@ http://purl.uniprot.org/uniprot/A0LQ64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/335543:SFUM_RS01455 ^@ http://purl.uniprot.org/uniprot/A0LEY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS21140 ^@ http://purl.uniprot.org/uniprot/A0LQR5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS13080 ^@ http://purl.uniprot.org/uniprot/A0LLA7 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/335543:SFUM_RS10740 ^@ http://purl.uniprot.org/uniprot/A0LK06 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS10810 ^@ http://purl.uniprot.org/uniprot/A0LK20 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/335543:SFUM_RS09850 ^@ http://purl.uniprot.org/uniprot/A0LJJ1 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/335543:SFUM_RS07125 ^@ http://purl.uniprot.org/uniprot/A0LI09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/335543:SFUM_RS08870 ^@ http://purl.uniprot.org/uniprot/A0LJ02 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/335543:SFUM_RS13390 ^@ http://purl.uniprot.org/uniprot/A0LLF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/335543:SFUM_RS08180 ^@ http://purl.uniprot.org/uniprot/A0LIL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/335543:SFUM_RS20130 ^@ http://purl.uniprot.org/uniprot/A0LQ67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS11400 ^@ http://purl.uniprot.org/uniprot/A0LKD3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS04230 ^@ http://purl.uniprot.org/uniprot/A0LGG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/335543:SFUM_RS14075 ^@ http://purl.uniprot.org/uniprot/A0LLU2 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/335543:SFUM_RS14985 ^@ http://purl.uniprot.org/uniprot/A0LMB1 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/335543:SFUM_RS06465 ^@ http://purl.uniprot.org/uniprot/A0LHN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/335543:SFUM_RS00125 ^@ http://purl.uniprot.org/uniprot/A0LE71 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/335543:SFUM_RS05170 ^@ http://purl.uniprot.org/uniprot/A0LGY6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/335543:SFUM_RS04925 ^@ http://purl.uniprot.org/uniprot/A0LGU2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS02825 ^@ http://purl.uniprot.org/uniprot/A0LFP5 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/335543:SFUM_RS14615 ^@ http://purl.uniprot.org/uniprot/A0LM45 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/335543:SFUM_RS10430 ^@ http://purl.uniprot.org/uniprot/A0LJU6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS21605 ^@ http://purl.uniprot.org/uniprot/A0LIE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS17860 ^@ http://purl.uniprot.org/uniprot/A0LNX7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/335543:SFUM_RS12295 ^@ http://purl.uniprot.org/uniprot/A0LKV6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/335543:SFUM_RS10925 ^@ http://purl.uniprot.org/uniprot/A0LK43 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/335543:SFUM_RS03860 ^@ http://purl.uniprot.org/uniprot/A0LG87 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/335543:SFUM_RS12900 ^@ http://purl.uniprot.org/uniprot/A0LL74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS18115 ^@ http://purl.uniprot.org/uniprot/A0LP27 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/335543:SFUM_RS08165 ^@ http://purl.uniprot.org/uniprot/A0LIL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/335543:SFUM_RS16415 ^@ http://purl.uniprot.org/uniprot/A0LN46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS07280 ^@ http://purl.uniprot.org/uniprot/A0LI41 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/335543:SFUM_RS03885 ^@ http://purl.uniprot.org/uniprot/A0LG91 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/335543:SFUM_RS15320 ^@ http://purl.uniprot.org/uniprot/A0LMH6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/335543:SFUM_RS12785 ^@ http://purl.uniprot.org/uniprot/A0LL53 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/335543:SFUM_RS18870 ^@ http://purl.uniprot.org/uniprot/A0LPG7 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/335543:SFUM_RS13590 ^@ http://purl.uniprot.org/uniprot/A0LLJ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/335543:SFUM_RS10115 ^@ http://purl.uniprot.org/uniprot/A0LJN8 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/335543:SFUM_RS04635 ^@ http://purl.uniprot.org/uniprot/A0LGN8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/335543:SFUM_RS13525 ^@ http://purl.uniprot.org/uniprot/A0LLI4 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/335543:SFUM_RS18700 ^@ http://purl.uniprot.org/uniprot/A0LPD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS16840 ^@ http://purl.uniprot.org/uniprot/A0LNC7 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/335543:SFUM_RS16870 ^@ http://purl.uniprot.org/uniprot/A0LND3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/335543:SFUM_RS21720 ^@ http://purl.uniprot.org/uniprot/A0LJN7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/335543:SFUM_RS17135 ^@ http://purl.uniprot.org/uniprot/A0LNI7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/335543:SFUM_RS20110 ^@ http://purl.uniprot.org/uniprot/A0LQ63 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/335543:SFUM_RS06100 ^@ http://purl.uniprot.org/uniprot/A0LHG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/335543:SFUM_RS08970 ^@ http://purl.uniprot.org/uniprot/A0LJ21 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.