http://togogenome.org/gene/368408:TPEN_RS01630 ^@ http://purl.uniprot.org/uniprot/A1RX00 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/368408:TPEN_RS05595 ^@ http://purl.uniprot.org/uniprot/A1RZ56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS08740 ^@ http://purl.uniprot.org/uniprot/A1S0X9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/368408:TPEN_RS03320 ^@ http://purl.uniprot.org/uniprot/A1RXW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/368408:TPEN_RS07465 ^@ http://purl.uniprot.org/uniprot/A1S074 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/368408:TPEN_RS00465 ^@ http://purl.uniprot.org/uniprot/A1RWC4 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/368408:TPEN_RS04265 ^@ http://purl.uniprot.org/uniprot/A1RYE7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/368408:TPEN_RS01210 ^@ http://purl.uniprot.org/uniprot/A1RWS3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/368408:TPEN_RS02675 ^@ http://purl.uniprot.org/uniprot/A1RXJ1 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS05180 ^@ http://purl.uniprot.org/uniprot/A1RYX4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/368408:TPEN_RS05940 ^@ http://purl.uniprot.org/uniprot/A1RZC3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/368408:TPEN_RS08285 ^@ http://purl.uniprot.org/uniprot/A1S0N7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/368408:TPEN_RS02955 ^@ http://purl.uniprot.org/uniprot/A1RXP8 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS02295 ^@ http://purl.uniprot.org/uniprot/A1RXC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02535 ^@ http://purl.uniprot.org/uniprot/A1RXG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS02095 ^@ http://purl.uniprot.org/uniprot/A1RX87 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/368408:TPEN_RS02310 ^@ http://purl.uniprot.org/uniprot/A1RXC7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/368408:TPEN_RS01435 ^@ http://purl.uniprot.org/uniprot/A1RWW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/368408:TPEN_RS00065 ^@ http://purl.uniprot.org/uniprot/A1RW43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS00730 ^@ http://purl.uniprot.org/uniprot/A1RWH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS03345 ^@ http://purl.uniprot.org/uniprot/A1RXW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/368408:TPEN_RS02830 ^@ http://purl.uniprot.org/uniprot/A1RXM2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/368408:TPEN_RS08010 ^@ http://purl.uniprot.org/uniprot/A1S0I2 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/368408:TPEN_RS05390 ^@ http://purl.uniprot.org/uniprot/A1RZ16 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/368408:TPEN_RS09370 ^@ http://purl.uniprot.org/uniprot/A1S1A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS04125 ^@ http://purl.uniprot.org/uniprot/A1RYC0 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/368408:TPEN_RS00135 ^@ http://purl.uniprot.org/uniprot/A1RW56 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/368408:TPEN_RS07645 ^@ http://purl.uniprot.org/uniprot/A1S0B0 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/368408:TPEN_RS02165 ^@ http://purl.uniprot.org/uniprot/A1RXA1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/368408:TPEN_RS00675 ^@ http://purl.uniprot.org/uniprot/A1RWG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/368408:TPEN_RS05845 ^@ http://purl.uniprot.org/uniprot/A1RZA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01955 ^@ http://purl.uniprot.org/uniprot/A1RX63 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.|||Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds via a cis-phosphoenolate intermediate. http://togogenome.org/gene/368408:TPEN_RS02900 ^@ http://purl.uniprot.org/uniprot/A1RXN6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 4 family.|||Binds 1 zinc ion per subunit.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/368408:TPEN_RS01205 ^@ http://purl.uniprot.org/uniprot/A1RWS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/368408:TPEN_RS04155 ^@ http://purl.uniprot.org/uniprot/A1RYC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS09065 ^@ http://purl.uniprot.org/uniprot/A1S143 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/368408:TPEN_RS01825 ^@ http://purl.uniprot.org/uniprot/A1RX37 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS03150 ^@ http://purl.uniprot.org/uniprot/A1RXS8 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/368408:TPEN_RS01445 ^@ http://purl.uniprot.org/uniprot/A1RWW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/368408:TPEN_RS05775 ^@ http://purl.uniprot.org/uniprot/A1RZ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/368408:TPEN_RS03015 ^@ http://purl.uniprot.org/uniprot/A1RXQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp41 subfamily.|||Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS06770 ^@ http://purl.uniprot.org/uniprot/A1RZT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/368408:TPEN_RS05415 ^@ http://purl.uniprot.org/uniprot/A1RZ21 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. PoK subfamily.|||Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. http://togogenome.org/gene/368408:TPEN_RS03515 ^@ http://purl.uniprot.org/uniprot/A1RY02 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/368408:TPEN_RS05955 ^@ http://purl.uniprot.org/uniprot/A1RZC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/368408:TPEN_RS08365 ^@ http://purl.uniprot.org/uniprot/A1S0Q3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/368408:TPEN_RS00035 ^@ http://purl.uniprot.org/uniprot/A1RW37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS04675 ^@ http://purl.uniprot.org/uniprot/A1RYM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/368408:TPEN_RS03210 ^@ http://purl.uniprot.org/uniprot/A1RXU0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/368408:TPEN_RS00485 ^@ http://purl.uniprot.org/uniprot/A1RWC8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeal riboflavin kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). http://togogenome.org/gene/368408:TPEN_RS08770 ^@ http://purl.uniprot.org/uniprot/A1S0Y5 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/368408:TPEN_RS05660 ^@ http://purl.uniprot.org/uniprot/A1RZ69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03535 ^@ http://purl.uniprot.org/uniprot/A1RY06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTH2 family.|||Cytoplasm|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/368408:TPEN_RS08065 ^@ http://purl.uniprot.org/uniprot/A1S0J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07215 ^@ http://purl.uniprot.org/uniprot/A1S026 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/368408:TPEN_RS01345 ^@ http://purl.uniprot.org/uniprot/A1RWU9 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/368408:TPEN_RS03425 ^@ http://purl.uniprot.org/uniprot/A1RXY3 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/368408:TPEN_RS01715 ^@ http://purl.uniprot.org/uniprot/A1RX16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/368408:TPEN_RS00705 ^@ http://purl.uniprot.org/uniprot/A1RWH2 ^@ Similarity ^@ Belongs to the SurE nucleotidase family. http://togogenome.org/gene/368408:TPEN_RS09070 ^@ http://purl.uniprot.org/uniprot/A1S144 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS08060 ^@ http://purl.uniprot.org/uniprot/A1S0J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01985 ^@ http://purl.uniprot.org/uniprot/A1RX69 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/368408:TPEN_RS07450 ^@ http://purl.uniprot.org/uniprot/A1S071 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/368408:TPEN_RS01080 ^@ http://purl.uniprot.org/uniprot/A1RWP7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS04295 ^@ http://purl.uniprot.org/uniprot/A1RYF3 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/368408:TPEN_RS05915 ^@ http://purl.uniprot.org/uniprot/A1RZB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS05980 ^@ http://purl.uniprot.org/uniprot/A1RZD1 ^@ Similarity ^@ Belongs to the CTP synthase family. http://togogenome.org/gene/368408:TPEN_RS07915 ^@ http://purl.uniprot.org/uniprot/A1S0G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03695 ^@ http://purl.uniprot.org/uniprot/A1RY36 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/368408:TPEN_RS02585 ^@ http://purl.uniprot.org/uniprot/A1RXH6 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. http://togogenome.org/gene/368408:TPEN_RS05800 ^@ http://purl.uniprot.org/uniprot/A1RZ96 ^@ Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS05275 ^@ http://purl.uniprot.org/uniprot/A1RYZ3 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. http://togogenome.org/gene/368408:TPEN_RS08870 ^@ http://purl.uniprot.org/uniprot/A1S104 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06340 ^@ http://purl.uniprot.org/uniprot/A1RZK4 ^@ Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family. http://togogenome.org/gene/368408:TPEN_RS03585 ^@ http://purl.uniprot.org/uniprot/A1RY15 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/368408:TPEN_RS05450 ^@ http://purl.uniprot.org/uniprot/A1RZ28 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/368408:TPEN_RS06205 ^@ http://purl.uniprot.org/uniprot/A1RZH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01325 ^@ http://purl.uniprot.org/uniprot/A1RWU5 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/368408:TPEN_RS03245 ^@ http://purl.uniprot.org/uniprot/A1RXU7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. http://togogenome.org/gene/368408:TPEN_RS00335 ^@ http://purl.uniprot.org/uniprot/A1RW96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02125 ^@ http://purl.uniprot.org/uniprot/A1RX93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/368408:TPEN_RS07710 ^@ http://purl.uniprot.org/uniprot/A1S0C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02510 ^@ http://purl.uniprot.org/uniprot/A1RXG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/368408:TPEN_RS03260 ^@ http://purl.uniprot.org/uniprot/A1RXV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 2 subfamily.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS06055 ^@ http://purl.uniprot.org/uniprot/A1RZE6 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/368408:TPEN_RS07425 ^@ http://purl.uniprot.org/uniprot/A1S066 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.|||Cell membrane|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/368408:TPEN_RS08375 ^@ http://purl.uniprot.org/uniprot/A1S0Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07445 ^@ http://purl.uniprot.org/uniprot/A1S070 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/368408:TPEN_RS04865 ^@ http://purl.uniprot.org/uniprot/A1RYR3 ^@ Caution|||Function|||Similarity ^@ Belongs to the Nre family.|||Involved in DNA damage repair.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS07650 ^@ http://purl.uniprot.org/uniprot/A1S0B1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/368408:TPEN_RS02335 ^@ http://purl.uniprot.org/uniprot/A1RXD2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/368408:TPEN_RS05950 ^@ http://purl.uniprot.org/uniprot/A1RZC5 ^@ Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Heterooligomer of catalytic and regulatory chains. http://togogenome.org/gene/368408:TPEN_RS01830 ^@ http://purl.uniprot.org/uniprot/A1RX38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP19 family.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/368408:TPEN_RS03010 ^@ http://purl.uniprot.org/uniprot/A1RXQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/368408:TPEN_RS02000 ^@ http://purl.uniprot.org/uniprot/A1RX72 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/368408:TPEN_RS05755 ^@ http://purl.uniprot.org/uniprot/A1RZ87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07565 ^@ http://purl.uniprot.org/uniprot/A1S094 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/368408:TPEN_RS07980 ^@ http://purl.uniprot.org/uniprot/A1S0H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02885 ^@ http://purl.uniprot.org/uniprot/A1RXN3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. http://togogenome.org/gene/368408:TPEN_RS01840 ^@ http://purl.uniprot.org/uniprot/A1RX40 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.|||Belongs to the asparaginase 1 family. GatD subfamily.|||Heterodimer of GatD and GatE. http://togogenome.org/gene/368408:TPEN_RS02525 ^@ http://purl.uniprot.org/uniprot/A1RXG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/368408:TPEN_RS04910 ^@ http://purl.uniprot.org/uniprot/A1RYS2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/368408:TPEN_RS03290 ^@ http://purl.uniprot.org/uniprot/A1RXV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Membrane http://togogenome.org/gene/368408:TPEN_RS09025 ^@ http://purl.uniprot.org/uniprot/A1S135 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/368408:TPEN_RS01000 ^@ http://purl.uniprot.org/uniprot/A1RWN1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/368408:TPEN_RS00270 ^@ http://purl.uniprot.org/uniprot/A1RW83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07920 ^@ http://purl.uniprot.org/uniprot/A1S0G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS04340 ^@ http://purl.uniprot.org/uniprot/A1RYG4 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/368408:TPEN_RS02665 ^@ http://purl.uniprot.org/uniprot/A1RXI9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/368408:TPEN_RS05705 ^@ http://purl.uniprot.org/uniprot/A1RZ78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06430 ^@ http://purl.uniprot.org/uniprot/A1RZM2 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/368408:TPEN_RS03950 ^@ http://purl.uniprot.org/uniprot/A1RY85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS04605 ^@ http://purl.uniprot.org/uniprot/A1RYL5 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/368408:TPEN_RS04210 ^@ http://purl.uniprot.org/uniprot/A1RYD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS06485 ^@ http://purl.uniprot.org/uniprot/A1RZN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 2 family.|||Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/368408:TPEN_RS00855 ^@ http://purl.uniprot.org/uniprot/A1RWK2 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/368408:TPEN_RS02685 ^@ http://purl.uniprot.org/uniprot/A1RXJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/368408:TPEN_RS07840 ^@ http://purl.uniprot.org/uniprot/A1S0E8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS00880 ^@ http://purl.uniprot.org/uniprot/A1RWK7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/368408:TPEN_RS02440 ^@ http://purl.uniprot.org/uniprot/A1RXE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS01625 ^@ http://purl.uniprot.org/uniprot/A1RWZ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS03050 ^@ http://purl.uniprot.org/uniprot/A1RXR1 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/368408:TPEN_RS02690 ^@ http://purl.uniprot.org/uniprot/A1RXJ4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/368408:TPEN_RS01740 ^@ http://purl.uniprot.org/uniprot/A1RX21 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. http://togogenome.org/gene/368408:TPEN_RS02810 ^@ http://purl.uniprot.org/uniprot/A1RXL8 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS02600 ^@ http://purl.uniprot.org/uniprot/A1RXH9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/368408:TPEN_RS03155 ^@ http://purl.uniprot.org/uniprot/A1RXS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.|||Belongs to the TiaS family.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS05935 ^@ http://purl.uniprot.org/uniprot/A1RZC2 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/368408:TPEN_RS00580 ^@ http://purl.uniprot.org/uniprot/A1RWE7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/368408:TPEN_RS08880 ^@ http://purl.uniprot.org/uniprot/A1S106 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03395 ^@ http://purl.uniprot.org/uniprot/A1RXX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/368408:TPEN_RS03885 ^@ http://purl.uniprot.org/uniprot/A1RY72 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/368408:TPEN_RS02575 ^@ http://purl.uniprot.org/uniprot/A1RXH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/368408:TPEN_RS03955 ^@ http://purl.uniprot.org/uniprot/A1RY86 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. UPF0219 family. http://togogenome.org/gene/368408:TPEN_RS06255 ^@ http://purl.uniprot.org/uniprot/A1RZI6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS03265 ^@ http://purl.uniprot.org/uniprot/A1RXV2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS04105 ^@ http://purl.uniprot.org/uniprot/A1RYB6 ^@ Similarity ^@ Belongs to the UPF0273 family. http://togogenome.org/gene/368408:TPEN_RS02135 ^@ http://purl.uniprot.org/uniprot/A1RX95 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/368408:TPEN_RS02805 ^@ http://purl.uniprot.org/uniprot/A1RXL7 ^@ Subunit ^@ Heterotetramer of one alpha, one beta, one delta and one gamma chain. http://togogenome.org/gene/368408:TPEN_RS02515 ^@ http://purl.uniprot.org/uniprot/A1RXG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS04040 ^@ http://purl.uniprot.org/uniprot/A1RYA3 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer composed of an alpha and a beta subunit.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/368408:TPEN_RS03215 ^@ http://purl.uniprot.org/uniprot/A1RXU1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/368408:TPEN_RS00050 ^@ http://purl.uniprot.org/uniprot/A1RW40 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/368408:TPEN_RS01415 ^@ http://purl.uniprot.org/uniprot/A1RWW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/368408:TPEN_RS00975 ^@ http://purl.uniprot.org/uniprot/A1RWM6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/368408:TPEN_RS06190 ^@ http://purl.uniprot.org/uniprot/A1RZH4 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/368408:TPEN_RS00960 ^@ http://purl.uniprot.org/uniprot/A1RWM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS05360 ^@ http://purl.uniprot.org/uniprot/A1RZ10 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/368408:TPEN_RS02200 ^@ http://purl.uniprot.org/uniprot/A1RXA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/368408:TPEN_RS00220 ^@ http://purl.uniprot.org/uniprot/A1RW73 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/368408:TPEN_RS02210 ^@ http://purl.uniprot.org/uniprot/A1RXB0 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL20 family.|||Part of the 50S ribosomal subunit. Binds 23S rRNA. http://togogenome.org/gene/368408:TPEN_RS02595 ^@ http://purl.uniprot.org/uniprot/A1RXH8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the archaeal DnaG primase family.|||Binds two Mg(2+) per subunit.|||Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome. http://togogenome.org/gene/368408:TPEN_RS08265 ^@ http://purl.uniprot.org/uniprot/A1S0N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS08050 ^@ http://purl.uniprot.org/uniprot/A1S0J0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/368408:TPEN_RS01405 ^@ http://purl.uniprot.org/uniprot/A1RWV9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/368408:TPEN_RS05625 ^@ http://purl.uniprot.org/uniprot/A1RZ62 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family. http://togogenome.org/gene/368408:TPEN_RS08105 ^@ http://purl.uniprot.org/uniprot/A1S0K1 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/368408:TPEN_RS00920 ^@ http://purl.uniprot.org/uniprot/A1RWL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02640 ^@ http://purl.uniprot.org/uniprot/A1RXI5 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/368408:TPEN_RS06285 ^@ http://purl.uniprot.org/uniprot/A1RZJ3 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/368408:TPEN_RS03330 ^@ http://purl.uniprot.org/uniprot/A1RXW6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS05990 ^@ http://purl.uniprot.org/uniprot/A1RZD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06050 ^@ http://purl.uniprot.org/uniprot/A1RZE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS09300 ^@ http://purl.uniprot.org/uniprot/A1S190 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/368408:TPEN_RS04400 ^@ http://purl.uniprot.org/uniprot/A1RYH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS04540 ^@ http://purl.uniprot.org/uniprot/A1RYK3 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/368408:TPEN_RS01105 ^@ http://purl.uniprot.org/uniprot/A1RWQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/368408:TPEN_RS02565 ^@ http://purl.uniprot.org/uniprot/A1RXH2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/368408:TPEN_RS01185 ^@ http://purl.uniprot.org/uniprot/A1RWR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS09360 ^@ http://purl.uniprot.org/uniprot/A1S1A2 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. http://togogenome.org/gene/368408:TPEN_RS07235 ^@ http://purl.uniprot.org/uniprot/A1S030 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/368408:TPEN_RS03445 ^@ http://purl.uniprot.org/uniprot/A1RXY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6B family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/368408:TPEN_RS05960 ^@ http://purl.uniprot.org/uniprot/A1RZC7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/368408:TPEN_RS08240 ^@ http://purl.uniprot.org/uniprot/A1S0M8 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/368408:TPEN_RS08465 ^@ http://purl.uniprot.org/uniprot/A1S0S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06295 ^@ http://purl.uniprot.org/uniprot/A1RZJ5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.|||Belongs to the RuBisCO large chain family. Type III subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.|||Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits. http://togogenome.org/gene/368408:TPEN_RS01920 ^@ http://purl.uniprot.org/uniprot/A1RX56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. Fibrillarin family.|||Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.|||Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. http://togogenome.org/gene/368408:TPEN_RS08985 ^@ http://purl.uniprot.org/uniprot/A1S127 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/368408:TPEN_RS05920 ^@ http://purl.uniprot.org/uniprot/A1RZB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS08290 ^@ http://purl.uniprot.org/uniprot/A1S0N8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/368408:TPEN_RS06535 ^@ http://purl.uniprot.org/uniprot/A1RZP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS00020 ^@ http://purl.uniprot.org/uniprot/A1RW34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS08415 ^@ http://purl.uniprot.org/uniprot/A1S0R3 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. http://togogenome.org/gene/368408:TPEN_RS08595 ^@ http://purl.uniprot.org/uniprot/A1S0U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03450 ^@ http://purl.uniprot.org/uniprot/A1RXY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6A family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/368408:TPEN_RS02645 ^@ http://purl.uniprot.org/uniprot/A1RXI6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/368408:TPEN_RS03220 ^@ http://purl.uniprot.org/uniprot/A1RXU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/368408:TPEN_RS08120 ^@ http://purl.uniprot.org/uniprot/A1S0K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS08025 ^@ http://purl.uniprot.org/uniprot/A1S0I5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/368408:TPEN_RS06950 ^@ http://purl.uniprot.org/uniprot/A1RZX3 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/368408:TPEN_RS02580 ^@ http://purl.uniprot.org/uniprot/A1RXH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/368408:TPEN_RS02555 ^@ http://purl.uniprot.org/uniprot/A1RXH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/368408:TPEN_RS02815 ^@ http://purl.uniprot.org/uniprot/A1RXL9 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS01010 ^@ http://purl.uniprot.org/uniprot/A1RWN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS08410 ^@ http://purl.uniprot.org/uniprot/A1S0R2 ^@ Cofactor|||Function|||Similarity ^@ Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).|||Binds 1 potassium ion per subunit.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/368408:TPEN_RS00835 ^@ http://purl.uniprot.org/uniprot/A1RWJ8 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/368408:TPEN_RS09130 ^@ http://purl.uniprot.org/uniprot/A1S156 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/368408:TPEN_RS01050 ^@ http://purl.uniprot.org/uniprot/A1RWP1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/368408:TPEN_RS02290 ^@ http://purl.uniprot.org/uniprot/A1RXC3 ^@ Function|||Similarity ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. http://togogenome.org/gene/368408:TPEN_RS07580 ^@ http://purl.uniprot.org/uniprot/A1S097 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/368408:TPEN_RS01660 ^@ http://purl.uniprot.org/uniprot/A1RX05 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/368408:TPEN_RS01680 ^@ http://purl.uniprot.org/uniprot/A1RX09 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/368408:TPEN_RS05710 ^@ http://purl.uniprot.org/uniprot/A1RZ79 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/368408:TPEN_RS01425 ^@ http://purl.uniprot.org/uniprot/A1RWW3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/368408:TPEN_RS03360 ^@ http://purl.uniprot.org/uniprot/A1RXX1 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/368408:TPEN_RS06435 ^@ http://purl.uniprot.org/uniprot/A1RZM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS06780 ^@ http://purl.uniprot.org/uniprot/A1RZT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/368408:TPEN_RS08855 ^@ http://purl.uniprot.org/uniprot/A1S101 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/368408:TPEN_RS04580 ^@ http://purl.uniprot.org/uniprot/A1RYL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/368408:TPEN_RS02540 ^@ http://purl.uniprot.org/uniprot/A1RXG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/368408:TPEN_RS05445 ^@ http://purl.uniprot.org/uniprot/A1RZ27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS03110 ^@ http://purl.uniprot.org/uniprot/A1RXS0 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/368408:TPEN_RS03065 ^@ http://purl.uniprot.org/uniprot/A1RXR2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS08865 ^@ http://purl.uniprot.org/uniprot/A1S103 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01615 ^@ http://purl.uniprot.org/uniprot/A1RWZ7 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/368408:TPEN_RS08510 ^@ http://purl.uniprot.org/uniprot/A1S0T2 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/368408:TPEN_RS00925 ^@ http://purl.uniprot.org/uniprot/A1RWL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS05905 ^@ http://purl.uniprot.org/uniprot/A1RZB6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS07905 ^@ http://purl.uniprot.org/uniprot/A1S0G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07410 ^@ http://purl.uniprot.org/uniprot/A1S063 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS00950 ^@ http://purl.uniprot.org/uniprot/A1RWM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS05685 ^@ http://purl.uniprot.org/uniprot/A1RZ74 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/368408:TPEN_RS07295 ^@ http://purl.uniprot.org/uniprot/A1S042 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/368408:TPEN_RS09295 ^@ http://purl.uniprot.org/uniprot/A1S189 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/368408:TPEN_RS06440 ^@ http://purl.uniprot.org/uniprot/A1RZM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS02100 ^@ http://purl.uniprot.org/uniprot/A1RX88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/368408:TPEN_RS09325 ^@ http://purl.uniprot.org/uniprot/A1S195 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/368408:TPEN_RS08560 ^@ http://purl.uniprot.org/uniprot/A1S0U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS00355 ^@ http://purl.uniprot.org/uniprot/A1RWA0 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/368408:TPEN_RS07945 ^@ http://purl.uniprot.org/uniprot/A1S0G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS04490 ^@ http://purl.uniprot.org/uniprot/A1RYJ3 ^@ Similarity ^@ Belongs to the PdaD family. http://togogenome.org/gene/368408:TPEN_RS01180 ^@ http://purl.uniprot.org/uniprot/A1RWR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/368408:TPEN_RS01370 ^@ http://purl.uniprot.org/uniprot/A1RWV4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/368408:TPEN_RS08130 ^@ http://purl.uniprot.org/uniprot/A1S0K6 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/368408:TPEN_RS03180 ^@ http://purl.uniprot.org/uniprot/A1RXT4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/368408:TPEN_RS06390 ^@ http://purl.uniprot.org/uniprot/A1RZL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS02305 ^@ http://purl.uniprot.org/uniprot/A1RXC6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/368408:TPEN_RS04625 ^@ http://purl.uniprot.org/uniprot/A1RYL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS00595 ^@ http://purl.uniprot.org/uniprot/A1RWF0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS03905 ^@ http://purl.uniprot.org/uniprot/A1RY76 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).|||Cytoplasm|||Homodimer.|||The N-terminal domain is an archaea-specific tRNA-editing domain that hydrolyzes incorrectly charged L-seryl-tRNA(Thr). Catalysis of tRNA editing is performed by the charged tRNA itself. http://togogenome.org/gene/368408:TPEN_RS06220 ^@ http://purl.uniprot.org/uniprot/A1RZH9 ^@ Similarity ^@ Belongs to the monomethylamine methyltransferase family. http://togogenome.org/gene/368408:TPEN_RS05585 ^@ http://purl.uniprot.org/uniprot/A1RZ54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01960 ^@ http://purl.uniprot.org/uniprot/A1RX64 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/368408:TPEN_RS01880 ^@ http://purl.uniprot.org/uniprot/A1RX48 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/368408:TPEN_RS03195 ^@ http://purl.uniprot.org/uniprot/A1RXT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS04715 ^@ http://purl.uniprot.org/uniprot/A1RYN7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/368408:TPEN_RS07705 ^@ http://purl.uniprot.org/uniprot/A1S0C2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01560 ^@ http://purl.uniprot.org/uniprot/A1RWY6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/368408:TPEN_RS09080 ^@ http://purl.uniprot.org/uniprot/A1S146 ^@ Caution|||Function|||Similarity ^@ Belongs to the Nre family.|||Involved in DNA damage repair.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS04615 ^@ http://purl.uniprot.org/uniprot/A1RYL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/368408:TPEN_RS00010 ^@ http://purl.uniprot.org/uniprot/A1RW32 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/368408:TPEN_RS02115 ^@ http://purl.uniprot.org/uniprot/A1RX91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07185 ^@ http://purl.uniprot.org/uniprot/A1S020 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03590 ^@ http://purl.uniprot.org/uniprot/A1RY16 ^@ Similarity ^@ Belongs to the UPF0200 family. http://togogenome.org/gene/368408:TPEN_RS01855 ^@ http://purl.uniprot.org/uniprot/A1RX43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/368408:TPEN_RS01770 ^@ http://purl.uniprot.org/uniprot/A1RX27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal histone HMF family.|||Chromosome|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS00875 ^@ http://purl.uniprot.org/uniprot/A1RWK6 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/368408:TPEN_RS03095 ^@ http://purl.uniprot.org/uniprot/A1RXR7 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/368408:TPEN_RS01170 ^@ http://purl.uniprot.org/uniprot/A1RWR5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS09320 ^@ http://purl.uniprot.org/uniprot/A1S194 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/368408:TPEN_RS02090 ^@ http://purl.uniprot.org/uniprot/A1RX86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS08325 ^@ http://purl.uniprot.org/uniprot/A1S0P5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/368408:TPEN_RS09235 ^@ http://purl.uniprot.org/uniprot/A1S177 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/368408:TPEN_RS01145 ^@ http://purl.uniprot.org/uniprot/A1RWR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/368408:TPEN_RS04695 ^@ http://purl.uniprot.org/uniprot/A1RYN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS02120 ^@ http://purl.uniprot.org/uniprot/A1RX92 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/368408:TPEN_RS06030 ^@ http://purl.uniprot.org/uniprot/A1RZE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07305 ^@ http://purl.uniprot.org/uniprot/A1S044 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. http://togogenome.org/gene/368408:TPEN_RS02155 ^@ http://purl.uniprot.org/uniprot/A1RXA0 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/368408:TPEN_RS06645 ^@ http://purl.uniprot.org/uniprot/A1RZR5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/368408:TPEN_RS04440 ^@ http://purl.uniprot.org/uniprot/A1RYI3 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/368408:TPEN_RS04330 ^@ http://purl.uniprot.org/uniprot/A1RYG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01480 ^@ http://purl.uniprot.org/uniprot/A1RWX1 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/368408:TPEN_RS01200 ^@ http://purl.uniprot.org/uniprot/A1RWS1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS04530 ^@ http://purl.uniprot.org/uniprot/A1RYK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/368408:TPEN_RS05680 ^@ http://purl.uniprot.org/uniprot/A1RZ73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07460 ^@ http://purl.uniprot.org/uniprot/A1S073 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS01330 ^@ http://purl.uniprot.org/uniprot/A1RWU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcL subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/368408:TPEN_RS03250 ^@ http://purl.uniprot.org/uniprot/A1RXU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/368408:TPEN_RS05240 ^@ http://purl.uniprot.org/uniprot/A1RYY6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/368408:TPEN_RS00645 ^@ http://purl.uniprot.org/uniprot/A1RWG0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/368408:TPEN_RS03670 ^@ http://purl.uniprot.org/uniprot/A1RY31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aTrm56 family.|||Cytoplasm|||Homodimer.|||Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. http://togogenome.org/gene/368408:TPEN_RS04380 ^@ http://purl.uniprot.org/uniprot/A1RYH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS00700 ^@ http://purl.uniprot.org/uniprot/A1RWH1 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/368408:TPEN_RS01285 ^@ http://purl.uniprot.org/uniprot/A1RWT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/368408:TPEN_RS07530 ^@ http://purl.uniprot.org/uniprot/A1S087 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/368408:TPEN_RS04020 ^@ http://purl.uniprot.org/uniprot/A1RY99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01245 ^@ http://purl.uniprot.org/uniprot/A1RWT0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS07615 ^@ http://purl.uniprot.org/uniprot/A1S0A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS03830 ^@ http://purl.uniprot.org/uniprot/A1RY61 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/368408:TPEN_RS04255 ^@ http://purl.uniprot.org/uniprot/A1RYE5 ^@ Similarity ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. http://togogenome.org/gene/368408:TPEN_RS07160 ^@ http://purl.uniprot.org/uniprot/A1S015 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07900 ^@ http://purl.uniprot.org/uniprot/A1S0G0 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/368408:TPEN_RS08125 ^@ http://purl.uniprot.org/uniprot/A1S0K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS08315 ^@ http://purl.uniprot.org/uniprot/A1S0P3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/368408:TPEN_RS01110 ^@ http://purl.uniprot.org/uniprot/A1RWQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. Probably involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA. http://togogenome.org/gene/368408:TPEN_RS03380 ^@ http://purl.uniprot.org/uniprot/A1RXX5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family. http://togogenome.org/gene/368408:TPEN_RS08355 ^@ http://purl.uniprot.org/uniprot/A1S0Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS05720 ^@ http://purl.uniprot.org/uniprot/A1RZ81 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/368408:TPEN_RS01810 ^@ http://purl.uniprot.org/uniprot/A1RX34 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/368408:TPEN_RS07470 ^@ http://purl.uniprot.org/uniprot/A1S075 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/368408:TPEN_RS02390 ^@ http://purl.uniprot.org/uniprot/A1RXE1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/368408:TPEN_RS05015 ^@ http://purl.uniprot.org/uniprot/A1RYU3 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/368408:TPEN_RS09210 ^@ http://purl.uniprot.org/uniprot/A1S172 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS09145 ^@ http://purl.uniprot.org/uniprot/A1S159 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS05510 ^@ http://purl.uniprot.org/uniprot/A1RZ39 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/368408:TPEN_RS01340 ^@ http://purl.uniprot.org/uniprot/A1RWU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS07435 ^@ http://purl.uniprot.org/uniprot/A1S068 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS02185 ^@ http://purl.uniprot.org/uniprot/A1RXA5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA. http://togogenome.org/gene/368408:TPEN_RS08140 ^@ http://purl.uniprot.org/uniprot/A1S0K8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS00620 ^@ http://purl.uniprot.org/uniprot/A1RWF5 ^@ Function|||Similarity ^@ Belongs to the TYW3 family.|||S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72. http://togogenome.org/gene/368408:TPEN_RS07550 ^@ http://purl.uniprot.org/uniprot/A1S091 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02550 ^@ http://purl.uniprot.org/uniprot/A1RXG9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/368408:TPEN_RS05370 ^@ http://purl.uniprot.org/uniprot/A1RZ12 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS02775 ^@ http://purl.uniprot.org/uniprot/A1RXL1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/368408:TPEN_RS04315 ^@ http://purl.uniprot.org/uniprot/A1RYF8 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. http://togogenome.org/gene/368408:TPEN_RS01540 ^@ http://purl.uniprot.org/uniprot/A1RWY2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity). http://togogenome.org/gene/368408:TPEN_RS01440 ^@ http://purl.uniprot.org/uniprot/A1RWW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta chain family.|||Cytoplasm|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/368408:TPEN_RS02175 ^@ http://purl.uniprot.org/uniprot/A1RXA3 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/368408:TPEN_RS01995 ^@ http://purl.uniprot.org/uniprot/A1RX71 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/368408:TPEN_RS02695 ^@ http://purl.uniprot.org/uniprot/A1RXJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/368408:TPEN_RS01100 ^@ http://purl.uniprot.org/uniprot/A1RWQ1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS02460 ^@ http://purl.uniprot.org/uniprot/A1RXF3 ^@ Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. http://togogenome.org/gene/368408:TPEN_RS05455 ^@ http://purl.uniprot.org/uniprot/A1RZ29 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/368408:TPEN_RS08565 ^@ http://purl.uniprot.org/uniprot/A1S0U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS02080 ^@ http://purl.uniprot.org/uniprot/A1RX84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SPT5 family.|||Belongs to the archaeal Spt5 family.|||Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).|||Stimulates transcription elongation. http://togogenome.org/gene/368408:TPEN_RS01590 ^@ http://purl.uniprot.org/uniprot/A1RWZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/368408:TPEN_RS00145 ^@ http://purl.uniprot.org/uniprot/A1RW58 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/368408:TPEN_RS01290 ^@ http://purl.uniprot.org/uniprot/A1RWT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/368408:TPEN_RS05030 ^@ http://purl.uniprot.org/uniprot/A1RYU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06830 ^@ http://purl.uniprot.org/uniprot/A1RZU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02975 ^@ http://purl.uniprot.org/uniprot/A1RXQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS04585 ^@ http://purl.uniprot.org/uniprot/A1RYL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS02225 ^@ http://purl.uniprot.org/uniprot/A1RXB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-archaeol synthase family.|||Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS02705 ^@ http://purl.uniprot.org/uniprot/A1RXJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSL4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. http://togogenome.org/gene/368408:TPEN_RS03805 ^@ http://purl.uniprot.org/uniprot/A1RY56 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/368408:TPEN_RS07540 ^@ http://purl.uniprot.org/uniprot/A1S089 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/368408:TPEN_RS08245 ^@ http://purl.uniprot.org/uniprot/A1S0M9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/368408:TPEN_RS03285 ^@ http://purl.uniprot.org/uniprot/A1RXV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GGGP/HepGP synthase family. Group II subfamily.|||Cytoplasm|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/368408:TPEN_RS02470 ^@ http://purl.uniprot.org/uniprot/A1RXF5 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/368408:TPEN_RS08420 ^@ http://purl.uniprot.org/uniprot/A1S0R4 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/368408:TPEN_RS09260 ^@ http://purl.uniprot.org/uniprot/A1S182 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/368408:TPEN_RS07440 ^@ http://purl.uniprot.org/uniprot/A1S069 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS06060 ^@ http://purl.uniprot.org/uniprot/A1RZE7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS03675 ^@ http://purl.uniprot.org/uniprot/A1RY32 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the TFE family.|||Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.|||The winged helix domain is involved in binding to DNA in the preinitiation complex.|||Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes. http://togogenome.org/gene/368408:TPEN_RS01935 ^@ http://purl.uniprot.org/uniprot/A1RX59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/368408:TPEN_RS09550 ^@ http://purl.uniprot.org/uniprot/A1S1E0 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/368408:TPEN_RS01140 ^@ http://purl.uniprot.org/uniprot/A1RWQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS02385 ^@ http://purl.uniprot.org/uniprot/A1RXE0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/368408:TPEN_RS07455 ^@ http://purl.uniprot.org/uniprot/A1S072 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS01875 ^@ http://purl.uniprot.org/uniprot/A1RX47 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS01890 ^@ http://purl.uniprot.org/uniprot/A1RX50 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/368408:TPEN_RS01505 ^@ http://purl.uniprot.org/uniprot/A1RWX6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL40 family. http://togogenome.org/gene/368408:TPEN_RS05855 ^@ http://purl.uniprot.org/uniprot/A1RZA7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/368408:TPEN_RS07610 ^@ http://purl.uniprot.org/uniprot/A1S0A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07515 ^@ http://purl.uniprot.org/uniprot/A1S084 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/368408:TPEN_RS03510 ^@ http://purl.uniprot.org/uniprot/A1RY01 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/368408:TPEN_RS04220 ^@ http://purl.uniprot.org/uniprot/A1RYD8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/368408:TPEN_RS08250 ^@ http://purl.uniprot.org/uniprot/A1S0N0 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/368408:TPEN_RS03665 ^@ http://purl.uniprot.org/uniprot/A1RY30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS03170 ^@ http://purl.uniprot.org/uniprot/A1RXT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/368408:TPEN_RS00110 ^@ http://purl.uniprot.org/uniprot/A1RW51 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/368408:TPEN_RS01360 ^@ http://purl.uniprot.org/uniprot/A1RWV2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS09055 ^@ http://purl.uniprot.org/uniprot/A1S141 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS05525 ^@ http://purl.uniprot.org/uniprot/A1RZ42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01135 ^@ http://purl.uniprot.org/uniprot/A1RWQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/368408:TPEN_RS01655 ^@ http://purl.uniprot.org/uniprot/A1RX04 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/368408:TPEN_RS03920 ^@ http://purl.uniprot.org/uniprot/A1RY79 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/368408:TPEN_RS02450 ^@ http://purl.uniprot.org/uniprot/A1RXF1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/368408:TPEN_RS06175 ^@ http://purl.uniprot.org/uniprot/A1RZH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS08215 ^@ http://purl.uniprot.org/uniprot/A1S0M3 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/368408:TPEN_RS03540 ^@ http://purl.uniprot.org/uniprot/A1RY07 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/368408:TPEN_RS00210 ^@ http://purl.uniprot.org/uniprot/A1RW71 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/368408:TPEN_RS07075 ^@ http://purl.uniprot.org/uniprot/A1RZZ8 ^@ Similarity ^@ Belongs to the archaeal ATPase family. http://togogenome.org/gene/368408:TPEN_RS00625 ^@ http://purl.uniprot.org/uniprot/A1RWF6 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/368408:TPEN_RS04700 ^@ http://purl.uniprot.org/uniprot/A1RYN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03935 ^@ http://purl.uniprot.org/uniprot/A1RY82 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/368408:TPEN_RS01395 ^@ http://purl.uniprot.org/uniprot/A1RWV7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/368408:TPEN_RS05970 ^@ http://purl.uniprot.org/uniprot/A1RZC9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS00930 ^@ http://purl.uniprot.org/uniprot/A1RWL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS02395 ^@ http://purl.uniprot.org/uniprot/A1RXE2 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/368408:TPEN_RS03895 ^@ http://purl.uniprot.org/uniprot/A1RY74 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/368408:TPEN_RS08885 ^@ http://purl.uniprot.org/uniprot/A1S107 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/368408:TPEN_RS01730 ^@ http://purl.uniprot.org/uniprot/A1RX19 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/368408:TPEN_RS07855 ^@ http://purl.uniprot.org/uniprot/A1S0F1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS07745 ^@ http://purl.uniprot.org/uniprot/A1S0D0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03025 ^@ http://purl.uniprot.org/uniprot/A1RXQ8 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/368408:TPEN_RS05380 ^@ http://purl.uniprot.org/uniprot/A1RZ14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/368408:TPEN_RS03410 ^@ http://purl.uniprot.org/uniprot/A1RXY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS06425 ^@ http://purl.uniprot.org/uniprot/A1RZM1 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/368408:TPEN_RS02960 ^@ http://purl.uniprot.org/uniprot/A1RXP9 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/368408:TPEN_RS08990 ^@ http://purl.uniprot.org/uniprot/A1S128 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/368408:TPEN_RS01815 ^@ http://purl.uniprot.org/uniprot/A1RX35 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeosine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. http://togogenome.org/gene/368408:TPEN_RS01420 ^@ http://purl.uniprot.org/uniprot/A1RWW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/368408:TPEN_RS00140 ^@ http://purl.uniprot.org/uniprot/A1RW57 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/368408:TPEN_RS00735 ^@ http://purl.uniprot.org/uniprot/A1RWH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS03185 ^@ http://purl.uniprot.org/uniprot/A1RXT5 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/368408:TPEN_RS01215 ^@ http://purl.uniprot.org/uniprot/A1RWS4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS05460 ^@ http://purl.uniprot.org/uniprot/A1RZ30 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/368408:TPEN_RS05350 ^@ http://purl.uniprot.org/uniprot/A1RZ08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS05570 ^@ http://purl.uniprot.org/uniprot/A1RZ51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS06040 ^@ http://purl.uniprot.org/uniprot/A1RZE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS01930 ^@ http://purl.uniprot.org/uniprot/A1RX58 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. http://togogenome.org/gene/368408:TPEN_RS06145 ^@ http://purl.uniprot.org/uniprot/A1RZG5 ^@ Similarity ^@ Belongs to the MscS (TC 1.A.23) family. http://togogenome.org/gene/368408:TPEN_RS09205 ^@ http://purl.uniprot.org/uniprot/A1S171 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS01335 ^@ http://purl.uniprot.org/uniprot/A1RWU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcS subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/368408:TPEN_RS01130 ^@ http://purl.uniprot.org/uniprot/A1RWQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/368408:TPEN_RS04805 ^@ http://purl.uniprot.org/uniprot/A1RYQ3 ^@ Similarity ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. http://togogenome.org/gene/368408:TPEN_RS01160 ^@ http://purl.uniprot.org/uniprot/A1RWR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/368408:TPEN_RS04690 ^@ http://purl.uniprot.org/uniprot/A1RYN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/368408:TPEN_RS03545 ^@ http://purl.uniprot.org/uniprot/A1RY08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).|||Cytoplasm http://togogenome.org/gene/368408:TPEN_RS07935 ^@ http://purl.uniprot.org/uniprot/A1S0G7 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/368408:TPEN_RS01230 ^@ http://purl.uniprot.org/uniprot/A1RWS7 ^@ Similarity ^@ Belongs to the UPF0215 family. http://togogenome.org/gene/368408:TPEN_RS04280 ^@ http://purl.uniprot.org/uniprot/A1RYF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/368408:TPEN_RS01365 ^@ http://purl.uniprot.org/uniprot/A1RWV3 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/368408:TPEN_RS05795 ^@ http://purl.uniprot.org/uniprot/A1RZ95 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/368408:TPEN_RS00260 ^@ http://purl.uniprot.org/uniprot/A1RW81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS06140 ^@ http://purl.uniprot.org/uniprot/A1RZG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS03525 ^@ http://purl.uniprot.org/uniprot/A1RY04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/368408:TPEN_RS08495 ^@ http://purl.uniprot.org/uniprot/A1S0S9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/368408:TPEN_RS02545 ^@ http://purl.uniprot.org/uniprot/A1RXG8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds to the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/368408:TPEN_RS02905 ^@ http://purl.uniprot.org/uniprot/A1RXN7 ^@ Function|||Similarity ^@ Belongs to the FAU-1 family.|||Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. http://togogenome.org/gene/368408:TPEN_RS04180 ^@ http://purl.uniprot.org/uniprot/A1RYD1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/368408:TPEN_RS01400 ^@ http://purl.uniprot.org/uniprot/A1RWV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/368408:TPEN_RS04770 ^@ http://purl.uniprot.org/uniprot/A1RYP8 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/368408:TPEN_RS08505 ^@ http://purl.uniprot.org/uniprot/A1S0T1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/368408:TPEN_RS04520 ^@ http://purl.uniprot.org/uniprot/A1RYJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/368408:TPEN_RS02825 ^@ http://purl.uniprot.org/uniprot/A1RXM1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/368408:TPEN_RS01225 ^@ http://purl.uniprot.org/uniprot/A1RWS6 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/368408:TPEN_RS02570 ^@ http://purl.uniprot.org/uniprot/A1RXH3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/368408:TPEN_RS05605 ^@ http://purl.uniprot.org/uniprot/A1RZ58 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/368408:TPEN_RS07995 ^@ http://purl.uniprot.org/uniprot/A1S0H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/368408:TPEN_RS05910 ^@ http://purl.uniprot.org/uniprot/A1RZB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/368408:TPEN_RS04660 ^@ http://purl.uniprot.org/uniprot/A1RYM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/368408:TPEN_RS02610 ^@ http://purl.uniprot.org/uniprot/A1RXI1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/368408:TPEN_RS04065 ^@ http://purl.uniprot.org/uniprot/A1RYA8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/368408:TPEN_RS00025 ^@ http://purl.uniprot.org/uniprot/A1RW35 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/368408:TPEN_RS03325 ^@ http://purl.uniprot.org/uniprot/A1RXW4 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/368408:TPEN_RS02915 ^@ http://purl.uniprot.org/uniprot/A1RXN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/368408:TPEN_RS03595 ^@ http://purl.uniprot.org/uniprot/A1RY17 ^@ Similarity ^@ Belongs to the UPF0201 family. http://togogenome.org/gene/368408:TPEN_RS04390 ^@ http://purl.uniprot.org/uniprot/A1RYH3 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/368408:TPEN_RS05420 ^@ http://purl.uniprot.org/uniprot/A1RZ22 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/368408:TPEN_RS00525 ^@ http://purl.uniprot.org/uniprot/A1RWD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 'phage' integrase family. XerA subfamily.|||Cytoplasm|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/368408:TPEN_RS00410 ^@ http://purl.uniprot.org/uniprot/A1RWB1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/368408:TPEN_RS05365 ^@ http://purl.uniprot.org/uniprot/A1RZ11 ^@ Subcellular Location Annotation ^@ Nucleus