http://togogenome.org/gene/580340:TLIE_RS00580 ^@ http://purl.uniprot.org/uniprot/G7V5V4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||Periplasm|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/580340:TLIE_RS01070 ^@ http://purl.uniprot.org/uniprot/G7V6C6 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/580340:TLIE_RS06545 ^@ http://purl.uniprot.org/uniprot/G7V607 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/580340:TLIE_RS04700 ^@ http://purl.uniprot.org/uniprot/G7V9U7 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/580340:TLIE_RS07420 ^@ http://purl.uniprot.org/uniprot/G7V6W8 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/580340:TLIE_RS03480 ^@ http://purl.uniprot.org/uniprot/G7V946 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS00150 ^@ http://purl.uniprot.org/uniprot/G7V5E8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS04345 ^@ http://purl.uniprot.org/uniprot/G7V9N2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS04080 ^@ http://purl.uniprot.org/uniprot/G7V9H8 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/580340:TLIE_RS01780 ^@ http://purl.uniprot.org/uniprot/G7V758 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04105 ^@ http://purl.uniprot.org/uniprot/G7V9I3 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/580340:TLIE_RS08850 ^@ http://purl.uniprot.org/uniprot/G7V8H6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01370 ^@ http://purl.uniprot.org/uniprot/G7V6Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS09435 ^@ http://purl.uniprot.org/uniprot/G7V911 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/580340:TLIE_RS06385 ^@ http://purl.uniprot.org/uniprot/G7V5Q2 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/580340:TLIE_RS05070 ^@ http://purl.uniprot.org/uniprot/G7VA16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/580340:TLIE_RS01755 ^@ http://purl.uniprot.org/uniprot/G7V753 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS03140 ^@ http://purl.uniprot.org/uniprot/G7V8Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/580340:TLIE_RS00845 ^@ http://purl.uniprot.org/uniprot/G7V682 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08870 ^@ http://purl.uniprot.org/uniprot/G7V8I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS00960 ^@ http://purl.uniprot.org/uniprot/G7V6A4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/580340:TLIE_RS09280 ^@ http://purl.uniprot.org/uniprot/G7V8Y7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01115 ^@ http://purl.uniprot.org/uniprot/G7V6D6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS05680 ^@ http://purl.uniprot.org/uniprot/G7VAD0 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/580340:TLIE_RS02505 ^@ http://purl.uniprot.org/uniprot/G7V7Y8 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS09295 ^@ http://purl.uniprot.org/uniprot/G7V8Z0 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/580340:TLIE_RS03895 ^@ http://purl.uniprot.org/uniprot/G7V9E5 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/580340:TLIE_RS03045 ^@ http://purl.uniprot.org/uniprot/G7V8G5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS09335 ^@ http://purl.uniprot.org/uniprot/G7V8Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03110 ^@ http://purl.uniprot.org/uniprot/G7V8Q0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/580340:TLIE_RS05485 ^@ http://purl.uniprot.org/uniprot/G7VAA0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/580340:TLIE_RS04980 ^@ http://purl.uniprot.org/uniprot/G7V9Z8 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/580340:TLIE_RS08570 ^@ http://purl.uniprot.org/uniprot/G7V851 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS02010 ^@ http://purl.uniprot.org/uniprot/G7V7H6 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/580340:TLIE_RS01220 ^@ http://purl.uniprot.org/uniprot/G7V6F2 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/580340:TLIE_RS05970 ^@ http://purl.uniprot.org/uniprot/G7V5A2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/580340:TLIE_RS03700 ^@ http://purl.uniprot.org/uniprot/G7V987 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/580340:TLIE_RS01495 ^@ http://purl.uniprot.org/uniprot/G7V6S6 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/580340:TLIE_RS07180 ^@ http://purl.uniprot.org/uniprot/G7V6J8 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/580340:TLIE_RS05660 ^@ http://purl.uniprot.org/uniprot/G7VAC6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS01315 ^@ http://purl.uniprot.org/uniprot/G7V6P2 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/580340:TLIE_RS06065 ^@ http://purl.uniprot.org/uniprot/G7V5C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Belongs to the CutA family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS08710 ^@ http://purl.uniprot.org/uniprot/G7V879 ^@ Similarity ^@ Belongs to the UPF0261 family. http://togogenome.org/gene/580340:TLIE_RS03335 ^@ http://purl.uniprot.org/uniprot/G7V8U4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/580340:TLIE_RS04690 ^@ http://purl.uniprot.org/uniprot/G7V9U5 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/580340:TLIE_RS08885 ^@ http://purl.uniprot.org/uniprot/G7V8I3 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/580340:TLIE_RS03300 ^@ http://purl.uniprot.org/uniprot/G7V8T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01880 ^@ http://purl.uniprot.org/uniprot/G7V778 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/580340:TLIE_RS04165 ^@ http://purl.uniprot.org/uniprot/G7V9J5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS06865 ^@ http://purl.uniprot.org/uniprot/G7V668 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/580340:TLIE_RS08100 ^@ http://purl.uniprot.org/uniprot/G7V7N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS09460 ^@ http://purl.uniprot.org/uniprot/G7V916 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/580340:TLIE_RS05920 ^@ http://purl.uniprot.org/uniprot/G7V592 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/580340:TLIE_RS07750 ^@ http://purl.uniprot.org/uniprot/G7V7A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03160 ^@ http://purl.uniprot.org/uniprot/G7V8R0 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/580340:TLIE_RS00420 ^@ http://purl.uniprot.org/uniprot/G7V5K1 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/580340:TLIE_RS03080 ^@ http://purl.uniprot.org/uniprot/G7V8P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/580340:TLIE_RS07380 ^@ http://purl.uniprot.org/uniprot/G7V6W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/580340:TLIE_RS03580 ^@ http://purl.uniprot.org/uniprot/G7V966 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05115 ^@ http://purl.uniprot.org/uniprot/G7VA25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/580340:TLIE_RS04495 ^@ http://purl.uniprot.org/uniprot/G7V9Q7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/580340:TLIE_RS05865 ^@ http://purl.uniprot.org/uniprot/G7V583 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/580340:TLIE_RS07985 ^@ http://purl.uniprot.org/uniprot/G7V7E6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS07840 ^@ http://purl.uniprot.org/uniprot/G7V7B9 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/580340:TLIE_RS05035 ^@ http://purl.uniprot.org/uniprot/G7VA09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS05140 ^@ http://purl.uniprot.org/uniprot/G7VA30 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS08780 ^@ http://purl.uniprot.org/uniprot/G7V892 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01110 ^@ http://purl.uniprot.org/uniprot/G7V6D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS02720 ^@ http://purl.uniprot.org/uniprot/G7V8A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/580340:TLIE_RS00860 ^@ http://purl.uniprot.org/uniprot/G7V685 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/580340:TLIE_RS07495 ^@ http://purl.uniprot.org/uniprot/G7V6Y3 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS06245 ^@ http://purl.uniprot.org/uniprot/G7V5M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05205 ^@ http://purl.uniprot.org/uniprot/G7VA43 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS02220 ^@ http://purl.uniprot.org/uniprot/G7V7L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06070 ^@ http://purl.uniprot.org/uniprot/G7V5C2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/580340:TLIE_RS06080 ^@ http://purl.uniprot.org/uniprot/G7V5C4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/580340:TLIE_RS04730 ^@ http://purl.uniprot.org/uniprot/G7V9V3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/580340:TLIE_RS00800 ^@ http://purl.uniprot.org/uniprot/G7V5Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS09420 ^@ http://purl.uniprot.org/uniprot/G7V908 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05950 ^@ http://purl.uniprot.org/uniprot/G7V598 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00715 ^@ http://purl.uniprot.org/uniprot/G7V5Y1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS06405 ^@ http://purl.uniprot.org/uniprot/G7V5Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01610 ^@ http://purl.uniprot.org/uniprot/G7V726 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06890 ^@ http://purl.uniprot.org/uniprot/G7V673 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/580340:TLIE_RS07230 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS03035 ^@ http://purl.uniprot.org/uniprot/G7V8G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS07410 ^@ http://purl.uniprot.org/uniprot/G7V6W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01195 ^@ http://purl.uniprot.org/uniprot/G7V6E7 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/580340:TLIE_RS02170 ^@ http://purl.uniprot.org/uniprot/G7V7K5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/580340:TLIE_RS01490 ^@ http://purl.uniprot.org/uniprot/G7V6S5 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/580340:TLIE_RS05005 ^@ http://purl.uniprot.org/uniprot/G7VA03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/580340:TLIE_RS05150 ^@ http://purl.uniprot.org/uniprot/G7VA32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/580340:TLIE_RS05040 ^@ http://purl.uniprot.org/uniprot/G7VA10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06630 ^@ http://purl.uniprot.org/uniprot/G7V624 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05690 ^@ http://purl.uniprot.org/uniprot/G7VAD2 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/580340:TLIE_RS07780 ^@ http://purl.uniprot.org/uniprot/G7V7A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS10275 ^@ http://purl.uniprot.org/uniprot/G7V7Z1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/580340:TLIE_RS00690 ^@ http://purl.uniprot.org/uniprot/G7V5X6 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/580340:TLIE_RS03710 ^@ http://purl.uniprot.org/uniprot/G7V990 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04810 ^@ http://purl.uniprot.org/uniprot/G7V9W8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/580340:TLIE_RS05760 ^@ http://purl.uniprot.org/uniprot/G7V563 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS07140 ^@ http://purl.uniprot.org/uniprot/G7V6J4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS06265 ^@ http://purl.uniprot.org/uniprot/G7V5N0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS05585 ^@ http://purl.uniprot.org/uniprot/G7VAB1 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/580340:TLIE_RS06180 ^@ http://purl.uniprot.org/uniprot/G7V5L5 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/580340:TLIE_RS04860 ^@ http://purl.uniprot.org/uniprot/G7V9X6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/580340:TLIE_RS06485 ^@ http://purl.uniprot.org/uniprot/G7V5S2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/580340:TLIE_RS05180 ^@ http://purl.uniprot.org/uniprot/G7VA38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/580340:TLIE_RS04960 ^@ http://purl.uniprot.org/uniprot/G7V9Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS07695 ^@ http://purl.uniprot.org/uniprot/G7V719 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/580340:TLIE_RS09175 ^@ http://purl.uniprot.org/uniprot/G7V8P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/580340:TLIE_RS05245 ^@ http://purl.uniprot.org/uniprot/G7VA51 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/580340:TLIE_RS09710 ^@ http://purl.uniprot.org/uniprot/G7VAE7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02070 ^@ http://purl.uniprot.org/uniprot/G7V7I8 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/580340:TLIE_RS03460 ^@ http://purl.uniprot.org/uniprot/G7V8X0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/580340:TLIE_RS00025 ^@ http://purl.uniprot.org/uniprot/G7V550 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/580340:TLIE_RS03030 ^@ http://purl.uniprot.org/uniprot/G7V8G2 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/580340:TLIE_RS04970 ^@ http://purl.uniprot.org/uniprot/G7V9Z6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/580340:TLIE_RS06090 ^@ http://purl.uniprot.org/uniprot/G7V5C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/580340:TLIE_RS03815 ^@ http://purl.uniprot.org/uniprot/G7V9B0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/580340:TLIE_RS06725 ^@ http://purl.uniprot.org/uniprot/G7V640 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/580340:TLIE_RS05160 ^@ http://purl.uniprot.org/uniprot/G7VA34 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/580340:TLIE_RS02985 ^@ http://purl.uniprot.org/uniprot/G7V8F3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS04480 ^@ http://purl.uniprot.org/uniprot/G7V9Q4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03445 ^@ http://purl.uniprot.org/uniprot/G7V8W7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/580340:TLIE_RS00305 ^@ http://purl.uniprot.org/uniprot/G7V5H9 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/580340:TLIE_RS09425 ^@ http://purl.uniprot.org/uniprot/G7V909 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS03925 ^@ http://purl.uniprot.org/uniprot/G7V9F0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS07150 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS02145 ^@ http://purl.uniprot.org/uniprot/G7V7K0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/580340:TLIE_RS00595 ^@ http://purl.uniprot.org/uniprot/G7V5V7 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/580340:TLIE_RS06730 ^@ http://purl.uniprot.org/uniprot/G7V641 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/580340:TLIE_RS01700 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS08240 ^@ http://purl.uniprot.org/uniprot/G7V7Q9 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/580340:TLIE_RS04475 ^@ http://purl.uniprot.org/uniprot/G7V9Q3 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/580340:TLIE_RS08615 ^@ http://purl.uniprot.org/uniprot/G7V860 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/580340:TLIE_RS05275 ^@ http://purl.uniprot.org/uniprot/G7VA57 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/580340:TLIE_RS02565 ^@ http://purl.uniprot.org/uniprot/G7V800 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS00465 ^@ http://purl.uniprot.org/uniprot/G7V5T1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/580340:TLIE_RS03830 ^@ http://purl.uniprot.org/uniprot/G7V9B3 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/580340:TLIE_RS09640 ^@ http://purl.uniprot.org/uniprot/G7V9C4 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/580340:TLIE_RS00710 ^@ http://purl.uniprot.org/uniprot/G7V5Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS01545 ^@ http://purl.uniprot.org/uniprot/G7V6T7 ^@ Function|||Similarity ^@ A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.|||Belongs to the DpnII type II restriction endonuclease family. http://togogenome.org/gene/580340:TLIE_RS09855 ^@ http://purl.uniprot.org/uniprot/G7V5T5 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/580340:TLIE_RS01075 ^@ http://purl.uniprot.org/uniprot/G7V6C7 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/580340:TLIE_RS04490 ^@ http://purl.uniprot.org/uniprot/G7V9Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS04760 ^@ http://purl.uniprot.org/uniprot/G7V9V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/580340:TLIE_RS02700 ^@ http://purl.uniprot.org/uniprot/G7V826 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/580340:TLIE_RS06830 ^@ http://purl.uniprot.org/uniprot/G7V661 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/580340:TLIE_RS04665 ^@ http://purl.uniprot.org/uniprot/G7V9U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS01205 ^@ http://purl.uniprot.org/uniprot/G7V6E9 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm4 family. http://togogenome.org/gene/580340:TLIE_RS00765 ^@ http://purl.uniprot.org/uniprot/G7V5Z0 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/580340:TLIE_RS01505 ^@ http://purl.uniprot.org/uniprot/G7V6S8 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/580340:TLIE_RS08120 ^@ http://purl.uniprot.org/uniprot/G7V7N5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS04675 ^@ http://purl.uniprot.org/uniprot/G7V9U2 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/580340:TLIE_RS08565 ^@ http://purl.uniprot.org/uniprot/G7V850 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03440 ^@ http://purl.uniprot.org/uniprot/G7V8W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/580340:TLIE_RS03290 ^@ http://purl.uniprot.org/uniprot/G7V8T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/580340:TLIE_RS08630 ^@ http://purl.uniprot.org/uniprot/G7V863 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/580340:TLIE_RS06055 ^@ http://purl.uniprot.org/uniprot/G7V5B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS00320 ^@ http://purl.uniprot.org/uniprot/G7V5I2 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/580340:TLIE_RS09960 ^@ http://purl.uniprot.org/uniprot/G7V9B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/580340:TLIE_RS06595 ^@ http://purl.uniprot.org/uniprot/G7V617 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/580340:TLIE_RS07440 ^@ http://purl.uniprot.org/uniprot/G7V6X2 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/580340:TLIE_RS07005 ^@ http://purl.uniprot.org/uniprot/G7V6G8 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/580340:TLIE_RS08940 ^@ http://purl.uniprot.org/uniprot/G7V8J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS02160 ^@ http://purl.uniprot.org/uniprot/G7V7K3 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/580340:TLIE_RS06100 ^@ http://purl.uniprot.org/uniprot/G7V5C8 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/580340:TLIE_RS04725 ^@ http://purl.uniprot.org/uniprot/G7V9V2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03305 ^@ http://purl.uniprot.org/uniprot/G7V8T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/580340:TLIE_RS00740 ^@ http://purl.uniprot.org/uniprot/G7V5Y5 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/580340:TLIE_RS02530 ^@ http://purl.uniprot.org/uniprot/G7V7Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00750 ^@ http://purl.uniprot.org/uniprot/G7V5Y7 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/580340:TLIE_RS08415 ^@ http://purl.uniprot.org/uniprot/G7V7U7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/580340:TLIE_RS05730 ^@ http://purl.uniprot.org/uniprot/G7VAE0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/580340:TLIE_RS05370 ^@ http://purl.uniprot.org/uniprot/G7VA77 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/580340:TLIE_RS03770 ^@ http://purl.uniprot.org/uniprot/G7V9A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS09725 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS07645 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS06490 ^@ http://purl.uniprot.org/uniprot/G7V5S3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/580340:TLIE_RS08475 ^@ http://purl.uniprot.org/uniprot/G7V832 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03345 ^@ http://purl.uniprot.org/uniprot/G7V8U6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/580340:TLIE_RS06640 ^@ http://purl.uniprot.org/uniprot/G7V626 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/580340:TLIE_RS09125 ^@ http://purl.uniprot.org/uniprot/G7V8N2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/580340:TLIE_RS01810 ^@ http://purl.uniprot.org/uniprot/G7V764 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03585 ^@ http://purl.uniprot.org/uniprot/G7V967 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/580340:TLIE_RS04465 ^@ http://purl.uniprot.org/uniprot/G7V9Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/580340:TLIE_RS06225 ^@ http://purl.uniprot.org/uniprot/G7V5M2 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/580340:TLIE_RS04855 ^@ http://purl.uniprot.org/uniprot/G7V9X5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/580340:TLIE_RS05800 ^@ http://purl.uniprot.org/uniprot/G7V570 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/580340:TLIE_RS09990 ^@ http://purl.uniprot.org/uniprot/G7V9X3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/580340:TLIE_RS01095 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS03295 ^@ http://purl.uniprot.org/uniprot/G7V8T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/580340:TLIE_RS08845 ^@ http://purl.uniprot.org/uniprot/G7V8H5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08145 ^@ http://purl.uniprot.org/uniprot/G7V7P0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/580340:TLIE_RS04185 ^@ http://purl.uniprot.org/uniprot/G7V9J9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/580340:TLIE_RS00780 ^@ http://purl.uniprot.org/uniprot/G7V5Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS05265 ^@ http://purl.uniprot.org/uniprot/G7VA55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04205 ^@ http://purl.uniprot.org/uniprot/G7V9K3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/580340:TLIE_RS00950 ^@ http://purl.uniprot.org/uniprot/G7V6A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS04075 ^@ http://purl.uniprot.org/uniprot/G7V9H7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell inner membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/580340:TLIE_RS05925 ^@ http://purl.uniprot.org/uniprot/G7V593 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/580340:TLIE_RS05700 ^@ http://purl.uniprot.org/uniprot/G7VAD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/580340:TLIE_RS03715 ^@ http://purl.uniprot.org/uniprot/G7V991 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS00050 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS00760 ^@ http://purl.uniprot.org/uniprot/G7V5Y9 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/580340:TLIE_RS07325 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS08680 ^@ http://purl.uniprot.org/uniprot/G7V873 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00340 ^@ http://purl.uniprot.org/uniprot/G7V5I6 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/580340:TLIE_RS06885 ^@ http://purl.uniprot.org/uniprot/G7V672 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/580340:TLIE_RS09740 ^@ http://purl.uniprot.org/uniprot/G7VAF3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/580340:TLIE_RS08665 ^@ http://purl.uniprot.org/uniprot/G7V870 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS05295 ^@ http://purl.uniprot.org/uniprot/G7VA61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/580340:TLIE_RS03360 ^@ http://purl.uniprot.org/uniprot/G7V8U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS10440 ^@ http://purl.uniprot.org/uniprot/G7V5X1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/580340:TLIE_RS03385 ^@ http://purl.uniprot.org/uniprot/G7V8V4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/580340:TLIE_RS03940 ^@ http://purl.uniprot.org/uniprot/G7V9F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/580340:TLIE_RS09490 ^@ http://purl.uniprot.org/uniprot/G7V922 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/580340:TLIE_RS03370 ^@ http://purl.uniprot.org/uniprot/G7V8V1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS07725 ^@ http://purl.uniprot.org/uniprot/G7V798 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/580340:TLIE_RS06020 ^@ http://purl.uniprot.org/uniprot/G7V5B1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS00100 ^@ http://purl.uniprot.org/uniprot/G7V5D8 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/580340:TLIE_RS01510 ^@ http://purl.uniprot.org/uniprot/G7V6T0 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/580340:TLIE_RS09545 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS00285 ^@ http://purl.uniprot.org/uniprot/G7V5H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS03410 ^@ http://purl.uniprot.org/uniprot/G7V8V9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS09245 ^@ http://purl.uniprot.org/uniprot/G7V8Y1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS03730 ^@ http://purl.uniprot.org/uniprot/G7V994 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/580340:TLIE_RS06985 ^@ http://purl.uniprot.org/uniprot/G7V6G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/580340:TLIE_RS06760 ^@ http://purl.uniprot.org/uniprot/G7V647 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/580340:TLIE_RS05910 ^@ http://purl.uniprot.org/uniprot/G7V590 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/580340:TLIE_RS01135 ^@ http://purl.uniprot.org/uniprot/G7V6E0 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/580340:TLIE_RS08865 ^@ http://purl.uniprot.org/uniprot/G7V8H9 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/580340:TLIE_RS03630 ^@ http://purl.uniprot.org/uniprot/G7V976 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/580340:TLIE_RS08345 ^@ http://purl.uniprot.org/uniprot/G7V7T3 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/580340:TLIE_RS06045 ^@ http://purl.uniprot.org/uniprot/G7V5B6 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03380 ^@ http://purl.uniprot.org/uniprot/G7V8V3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/580340:TLIE_RS09865 ^@ http://purl.uniprot.org/uniprot/G7V6B6 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/580340:TLIE_RS04975 ^@ http://purl.uniprot.org/uniprot/G7V9Z7 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/580340:TLIE_RS06095 ^@ http://purl.uniprot.org/uniprot/G7V5C7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS08180 ^@ http://purl.uniprot.org/uniprot/G7V7P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00515 ^@ http://purl.uniprot.org/uniprot/G7V5U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/580340:TLIE_RS08500 ^@ http://purl.uniprot.org/uniprot/G7V837 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/580340:TLIE_RS02445 ^@ http://purl.uniprot.org/uniprot/G7V7X6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS01560 ^@ http://purl.uniprot.org/uniprot/G7V6T9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS09885 ^@ http://purl.uniprot.org/uniprot/G7V6U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS07760 ^@ http://purl.uniprot.org/uniprot/G7V7A5 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/580340:TLIE_RS04625 ^@ http://purl.uniprot.org/uniprot/G7V9T2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/580340:TLIE_RS06950 ^@ http://purl.uniprot.org/uniprot/G7V6F7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/580340:TLIE_RS04705 ^@ http://purl.uniprot.org/uniprot/G7V9U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/580340:TLIE_RS08040 ^@ http://purl.uniprot.org/uniprot/G7V7F7 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS08105 ^@ http://purl.uniprot.org/uniprot/G7V7N2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS04635 ^@ http://purl.uniprot.org/uniprot/G7V9T4 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/580340:TLIE_RS07090 ^@ http://purl.uniprot.org/uniprot/G7V6I4 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/580340:TLIE_RS05410 ^@ http://purl.uniprot.org/uniprot/G7VA85 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/580340:TLIE_RS02690 ^@ http://purl.uniprot.org/uniprot/G7V824 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/580340:TLIE_RS01650 ^@ http://purl.uniprot.org/uniprot/G7V734 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS06845 ^@ http://purl.uniprot.org/uniprot/G7V664 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/580340:TLIE_RS07910 ^@ http://purl.uniprot.org/uniprot/G7V7D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS07080 ^@ http://purl.uniprot.org/uniprot/G7V6I2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/580340:TLIE_RS05430 ^@ http://purl.uniprot.org/uniprot/G7VA89 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/580340:TLIE_RS06690 ^@ http://purl.uniprot.org/uniprot/G7V634 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/580340:TLIE_RS05335 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS09690 ^@ http://purl.uniprot.org/uniprot/G7V9D4 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/580340:TLIE_RS07755 ^@ http://purl.uniprot.org/uniprot/G7V7A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS09995 ^@ http://purl.uniprot.org/uniprot/G7V9Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03210 ^@ http://purl.uniprot.org/uniprot/G7V8S0 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/580340:TLIE_RS08000 ^@ http://purl.uniprot.org/uniprot/G7V7E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS05240 ^@ http://purl.uniprot.org/uniprot/G7VA50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/580340:TLIE_RS09520 ^@ http://purl.uniprot.org/uniprot/G7V927 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01585 ^@ http://purl.uniprot.org/uniprot/G7V6U4 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/580340:TLIE_RS00255 ^@ http://purl.uniprot.org/uniprot/G7V5G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS03570 ^@ http://purl.uniprot.org/uniprot/G7V964 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03415 ^@ http://purl.uniprot.org/uniprot/G7V8W0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/580340:TLIE_RS04485 ^@ http://purl.uniprot.org/uniprot/G7V9Q5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS08620 ^@ http://purl.uniprot.org/uniprot/G7V861 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/580340:TLIE_RS05165 ^@ http://purl.uniprot.org/uniprot/G7VA35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS02150 ^@ http://purl.uniprot.org/uniprot/G7V7K1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/580340:TLIE_RS02500 ^@ http://purl.uniprot.org/uniprot/G7V7Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS04645 ^@ http://purl.uniprot.org/uniprot/G7V9T6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS01445 ^@ http://purl.uniprot.org/uniprot/G7V6R7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS02430 ^@ http://purl.uniprot.org/uniprot/G7V7X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS03805 ^@ http://purl.uniprot.org/uniprot/G7V9A8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/580340:TLIE_RS08945 ^@ http://purl.uniprot.org/uniprot/G7V8J5 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/580340:TLIE_RS04750 ^@ http://purl.uniprot.org/uniprot/G7V9V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/580340:TLIE_RS06840 ^@ http://purl.uniprot.org/uniprot/G7V663 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/580340:TLIE_RS02125 ^@ http://purl.uniprot.org/uniprot/G7V7J6 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/580340:TLIE_RS07160 ^@ http://purl.uniprot.org/uniprot/G7V6J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/580340:TLIE_RS01865 ^@ http://purl.uniprot.org/uniprot/G7V775 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01405 ^@ http://purl.uniprot.org/uniprot/G7V6Q9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/580340:TLIE_RS09495 ^@ http://purl.uniprot.org/uniprot/G7V923 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/580340:TLIE_RS09735 ^@ http://purl.uniprot.org/uniprot/G7VAF2 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/580340:TLIE_RS02175 ^@ http://purl.uniprot.org/uniprot/G7V7K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/580340:TLIE_RS06925 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS02115 ^@ http://purl.uniprot.org/uniprot/G7V7J4 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS05555 ^@ http://purl.uniprot.org/uniprot/G7VAA5 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/580340:TLIE_RS02705 ^@ http://purl.uniprot.org/uniprot/G7V827 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/580340:TLIE_RS06960 ^@ http://purl.uniprot.org/uniprot/G7V6F9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/580340:TLIE_RS06105 ^@ http://purl.uniprot.org/uniprot/G7V5C9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/580340:TLIE_RS07630 ^@ http://purl.uniprot.org/uniprot/G7V708 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS00275 ^@ http://purl.uniprot.org/uniprot/G7V5H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS01355 ^@ http://purl.uniprot.org/uniprot/G7V6Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/580340:TLIE_RS05475 ^@ http://purl.uniprot.org/uniprot/G7VA98 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/580340:TLIE_RS01270 ^@ http://purl.uniprot.org/uniprot/G7V6N3 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/580340:TLIE_RS02080 ^@ http://purl.uniprot.org/uniprot/G7V7J0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS05705 ^@ http://purl.uniprot.org/uniprot/G7VAD5 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/580340:TLIE_RS06600 ^@ http://purl.uniprot.org/uniprot/G7V618 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/580340:TLIE_RS05875 ^@ http://purl.uniprot.org/uniprot/G7V584 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/580340:TLIE_RS06330 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS00300 ^@ http://purl.uniprot.org/uniprot/G7V5H8 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/580340:TLIE_RS08785 ^@ http://purl.uniprot.org/uniprot/G7V893 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/580340:TLIE_RS00075 ^@ http://purl.uniprot.org/uniprot/G7V560 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04520 ^@ http://purl.uniprot.org/uniprot/G7V9R2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/580340:TLIE_RS06290 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS08745 ^@ http://purl.uniprot.org/uniprot/G7V885 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS08890 ^@ http://purl.uniprot.org/uniprot/G7V8I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS02045 ^@ http://purl.uniprot.org/uniprot/G7V7I3 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/580340:TLIE_RS07365 ^@ http://purl.uniprot.org/uniprot/G7V6V7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/580340:TLIE_RS09030 ^@ http://purl.uniprot.org/uniprot/G7V8L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03085 ^@ http://purl.uniprot.org/uniprot/G7V8P5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/580340:TLIE_RS04280 ^@ http://purl.uniprot.org/uniprot/G7V9L9 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/580340:TLIE_RS09835 ^@ http://purl.uniprot.org/uniprot/G7VAH1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS04715 ^@ http://purl.uniprot.org/uniprot/G7V9V0 ^@ Caution|||Function|||Similarity ^@ Belongs to the RecR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/580340:TLIE_RS04670 ^@ http://purl.uniprot.org/uniprot/G7V9U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08515 ^@ http://purl.uniprot.org/uniprot/G7V840 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/580340:TLIE_RS03590 ^@ http://purl.uniprot.org/uniprot/G7V968 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS01965 ^@ http://purl.uniprot.org/uniprot/G7V795 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/580340:TLIE_RS03090 ^@ http://purl.uniprot.org/uniprot/G7V8P6 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS04355 ^@ http://purl.uniprot.org/uniprot/G7V9N4 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/580340:TLIE_RS03640 ^@ http://purl.uniprot.org/uniprot/G7V978 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03725 ^@ http://purl.uniprot.org/uniprot/G7V993 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/580340:TLIE_RS02685 ^@ http://purl.uniprot.org/uniprot/G7V823 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS01890 ^@ http://purl.uniprot.org/uniprot/G7V780 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/580340:TLIE_RS01185 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS03825 ^@ http://purl.uniprot.org/uniprot/G7V9B2 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS02130 ^@ http://purl.uniprot.org/uniprot/G7V7J7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/580340:TLIE_RS05960 ^@ http://purl.uniprot.org/uniprot/G7V5A0 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/580340:TLIE_RS05930 ^@ http://purl.uniprot.org/uniprot/G7V594 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/580340:TLIE_RS02860 ^@ http://purl.uniprot.org/uniprot/G7V8C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00725 ^@ http://purl.uniprot.org/uniprot/G7V5Y3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS06990 ^@ http://purl.uniprot.org/uniprot/G7V6G5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/580340:TLIE_RS00065 ^@ http://purl.uniprot.org/uniprot/G7V558 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS05745 ^@ http://purl.uniprot.org/uniprot/G7VAE3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS02260 ^@ http://purl.uniprot.org/uniprot/G7V7L9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/580340:TLIE_RS02995 ^@ http://purl.uniprot.org/uniprot/G7V8F5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS05445 ^@ http://purl.uniprot.org/uniprot/G7VA92 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/580340:TLIE_RS02545 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS03060 ^@ http://purl.uniprot.org/uniprot/G7V8G8 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/580340:TLIE_RS03945 ^@ http://purl.uniprot.org/uniprot/G7V9F4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/580340:TLIE_RS06505 ^@ http://purl.uniprot.org/uniprot/G7V5S6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS06835 ^@ http://purl.uniprot.org/uniprot/G7V662 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03095 ^@ http://purl.uniprot.org/uniprot/G7V8P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03365 ^@ http://purl.uniprot.org/uniprot/G7V8V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/580340:TLIE_RS05470 ^@ http://purl.uniprot.org/uniprot/G7VA97 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/580340:TLIE_RS09720 ^@ http://purl.uniprot.org/uniprot/G7VAE9 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/580340:TLIE_RS02895 ^@ http://purl.uniprot.org/uniprot/G7V8D6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/580340:TLIE_RS07980 ^@ http://purl.uniprot.org/uniprot/G7V7E5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/580340:TLIE_RS02165 ^@ http://purl.uniprot.org/uniprot/G7V7K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/580340:TLIE_RS04570 ^@ http://purl.uniprot.org/uniprot/G7V9S2 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS01665 ^@ http://purl.uniprot.org/uniprot/G7V737 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08360 ^@ http://purl.uniprot.org/uniprot/G7V7T6 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/580340:TLIE_RS03600 ^@ http://purl.uniprot.org/uniprot/G7V970 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/580340:TLIE_RS05360 ^@ http://purl.uniprot.org/uniprot/G7VA75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03215 ^@ http://purl.uniprot.org/uniprot/G7V8S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS07485 ^@ http://purl.uniprot.org/uniprot/G7V6Y1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS05695 ^@ http://purl.uniprot.org/uniprot/G7VAD3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02935 ^@ http://purl.uniprot.org/uniprot/G7V8E4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01995 ^@ http://purl.uniprot.org/uniprot/G7V7H3 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/580340:TLIE_RS00700 ^@ http://purl.uniprot.org/uniprot/G7V5X8 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/580340:TLIE_RS03450 ^@ http://purl.uniprot.org/uniprot/G7V8W8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/580340:TLIE_RS06280 ^@ http://purl.uniprot.org/uniprot/G7V5N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS00350 ^@ http://purl.uniprot.org/uniprot/G7V5I8 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/580340:TLIE_RS09405 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS09325 ^@ http://purl.uniprot.org/uniprot/G7V8Z5 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/580340:TLIE_RS05820 ^@ http://purl.uniprot.org/uniprot/G7V574 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/580340:TLIE_RS05330 ^@ http://purl.uniprot.org/uniprot/G7VA68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS03125 ^@ http://purl.uniprot.org/uniprot/G7V8Q3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/580340:TLIE_RS06450 ^@ http://purl.uniprot.org/uniprot/G7V5R5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/580340:TLIE_RS10280 ^@ http://purl.uniprot.org/uniprot/G7V7Z2 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/580340:TLIE_RS00535 ^@ http://purl.uniprot.org/uniprot/G7V5U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05580 ^@ http://purl.uniprot.org/uniprot/G7VAB0 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/580340:TLIE_RS05810 ^@ http://purl.uniprot.org/uniprot/G7V572 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS02510 ^@ http://purl.uniprot.org/uniprot/G7V7Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS02420 ^@ http://purl.uniprot.org/uniprot/G7V7X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS09210 ^@ http://purl.uniprot.org/uniprot/G7V8X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03695 ^@ http://purl.uniprot.org/uniprot/G7V986 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/580340:TLIE_RS07820 ^@ http://purl.uniprot.org/uniprot/G7V7B6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/580340:TLIE_RS03375 ^@ http://purl.uniprot.org/uniprot/G7V8V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/580340:TLIE_RS09080 ^@ http://purl.uniprot.org/uniprot/G7V8M3 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/580340:TLIE_RS00190 ^@ http://purl.uniprot.org/uniprot/G7V5F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/580340:TLIE_RS06465 ^@ http://purl.uniprot.org/uniprot/G7V5R8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/580340:TLIE_RS01850 ^@ http://purl.uniprot.org/uniprot/G7V772 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/580340:TLIE_RS00720 ^@ http://purl.uniprot.org/uniprot/G7V5Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS09230 ^@ http://purl.uniprot.org/uniprot/G7V8X8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/580340:TLIE_RS03900 ^@ http://purl.uniprot.org/uniprot/G7V9E6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS06500 ^@ http://purl.uniprot.org/uniprot/G7V5S5 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/580340:TLIE_RS09850 ^@ http://purl.uniprot.org/uniprot/G7V5I9 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/580340:TLIE_RS03550 ^@ http://purl.uniprot.org/uniprot/G7V960 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS02425 ^@ http://purl.uniprot.org/uniprot/G7V7X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS05220 ^@ http://purl.uniprot.org/uniprot/G7VA46 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/580340:TLIE_RS07000 ^@ http://purl.uniprot.org/uniprot/G7V6G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/580340:TLIE_RS04600 ^@ http://purl.uniprot.org/uniprot/G7V9S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS10435 ^@ http://purl.uniprot.org/uniprot/G7V5U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS08070 ^@ http://purl.uniprot.org/uniprot/G7V7G3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/580340:TLIE_RS05495 ^@ http://purl.uniprot.org/uniprot/G7VAA2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/580340:TLIE_RS01030 ^@ http://purl.uniprot.org/uniprot/G7V6B8 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/580340:TLIE_RS04010 ^@ http://purl.uniprot.org/uniprot/G7V9G7 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/580340:TLIE_RS04885 ^@ http://purl.uniprot.org/uniprot/G7V9Y0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/580340:TLIE_RS08895 ^@ http://purl.uniprot.org/uniprot/G7V8I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04470 ^@ http://purl.uniprot.org/uniprot/G7V9Q2 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/580340:TLIE_RS03625 ^@ http://purl.uniprot.org/uniprot/G7V975 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/580340:TLIE_RS05955 ^@ http://purl.uniprot.org/uniprot/G7V599 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS05380 ^@ http://purl.uniprot.org/uniprot/G7VA79 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/580340:TLIE_RS01290 ^@ http://purl.uniprot.org/uniprot/G7V6N7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. http://togogenome.org/gene/580340:TLIE_RS04695 ^@ http://purl.uniprot.org/uniprot/G7V9U6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/580340:TLIE_RS06750 ^@ http://purl.uniprot.org/uniprot/G7V645 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/580340:TLIE_RS01950 ^@ http://purl.uniprot.org/uniprot/G7V792 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/580340:TLIE_RS06120 ^@ http://purl.uniprot.org/uniprot/G7V5D2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/580340:TLIE_RS02695 ^@ http://purl.uniprot.org/uniprot/G7V825 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/580340:TLIE_RS09170 ^@ http://purl.uniprot.org/uniprot/G7V8P2 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/580340:TLIE_RS05320 ^@ http://purl.uniprot.org/uniprot/G7VA66 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/580340:TLIE_RS01920 ^@ http://purl.uniprot.org/uniprot/G7V786 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/580340:TLIE_RS00605 ^@ http://purl.uniprot.org/uniprot/G7V5V9 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/580340:TLIE_RS03860 ^@ http://purl.uniprot.org/uniprot/G7V9D8 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/580340:TLIE_RS00385 ^@ http://purl.uniprot.org/uniprot/G7V5J4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS04735 ^@ http://purl.uniprot.org/uniprot/G7V9V4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/580340:TLIE_RS06980 ^@ http://purl.uniprot.org/uniprot/G7V6G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS04450 ^@ http://purl.uniprot.org/uniprot/G7V9P8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/580340:TLIE_RS03340 ^@ http://purl.uniprot.org/uniprot/G7V8U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/580340:TLIE_RS04255 ^@ http://purl.uniprot.org/uniprot/G7V9L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS06615 ^@ http://purl.uniprot.org/uniprot/G7V621 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/580340:TLIE_RS07215 ^@ http://purl.uniprot.org/uniprot/G7V6K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06250 ^@ http://purl.uniprot.org/uniprot/G7V5M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06605 ^@ http://purl.uniprot.org/uniprot/G7V619 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/580340:TLIE_RS06395 ^@ http://purl.uniprot.org/uniprot/G7V5Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04230 ^@ http://purl.uniprot.org/uniprot/G7V9K9 ^@ Function ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. http://togogenome.org/gene/580340:TLIE_RS05130 ^@ http://purl.uniprot.org/uniprot/G7VA28 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS07620 ^@ http://purl.uniprot.org/uniprot/G7V706 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03355 ^@ http://purl.uniprot.org/uniprot/G7V8U8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/580340:TLIE_RS06740 ^@ http://purl.uniprot.org/uniprot/G7V643 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/580340:TLIE_RS03935 ^@ http://purl.uniprot.org/uniprot/G7V9F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/580340:TLIE_RS08640 ^@ http://purl.uniprot.org/uniprot/G7V865 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/580340:TLIE_RS07360 ^@ http://purl.uniprot.org/uniprot/G7V6V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS00260 ^@ http://purl.uniprot.org/uniprot/G7V5H0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/580340:TLIE_RS08485 ^@ http://purl.uniprot.org/uniprot/G7V834 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04005 ^@ http://purl.uniprot.org/uniprot/G7V9G6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/580340:TLIE_RS08450 ^@ http://purl.uniprot.org/uniprot/G7V7V4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/580340:TLIE_RS03850 ^@ http://purl.uniprot.org/uniprot/G7V9D6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS08250 ^@ http://purl.uniprot.org/uniprot/G7V7R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS04135 ^@ http://purl.uniprot.org/uniprot/G7V9I9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/580340:TLIE_RS08175 ^@ http://purl.uniprot.org/uniprot/G7V7P5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS09260 ^@ http://purl.uniprot.org/uniprot/G7V8Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS07615 ^@ http://purl.uniprot.org/uniprot/G7V705 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/580340:TLIE_RS00545 ^@ http://purl.uniprot.org/uniprot/G7V5U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS09975 ^@ http://purl.uniprot.org/uniprot/G7V9H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbxX/CfxQ family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02450 ^@ http://purl.uniprot.org/uniprot/G7V7X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03530 ^@ http://purl.uniprot.org/uniprot/G7V956 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/580340:TLIE_RS08385 ^@ http://purl.uniprot.org/uniprot/G7V7U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05650 ^@ http://purl.uniprot.org/uniprot/G7VAC4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS09225 ^@ http://purl.uniprot.org/uniprot/G7V8X7 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS01425 ^@ http://purl.uniprot.org/uniprot/G7V6R3 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/580340:TLIE_RS07320 ^@ http://purl.uniprot.org/uniprot/G7V6U9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/580340:TLIE_RS03575 ^@ http://purl.uniprot.org/uniprot/G7V965 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/580340:TLIE_RS08795 ^@ http://purl.uniprot.org/uniprot/G7V895 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00020 ^@ http://purl.uniprot.org/uniprot/G7V549 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/580340:TLIE_RS05625 ^@ http://purl.uniprot.org/uniprot/G7VAB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS09475 ^@ http://purl.uniprot.org/uniprot/G7V919 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS01400 ^@ http://purl.uniprot.org/uniprot/G7V6Q8 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/580340:TLIE_RS02585 ^@ http://purl.uniprot.org/uniprot/G7V804 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/580340:TLIE_RS05310 ^@ http://purl.uniprot.org/uniprot/G7VA64 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/580340:TLIE_RS05750 ^@ http://purl.uniprot.org/uniprot/G7VAE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/580340:TLIE_RS06510 ^@ http://purl.uniprot.org/uniprot/G7V5S7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/580340:TLIE_RS03975 ^@ http://purl.uniprot.org/uniprot/G7V9G0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/580340:TLIE_RS06970 ^@ http://purl.uniprot.org/uniprot/G7V6G1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched-chain polyamine synthase family.|||Cytoplasm|||Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine. http://togogenome.org/gene/580340:TLIE_RS04400 ^@ http://purl.uniprot.org/uniprot/G7V9N8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/580340:TLIE_RS07830 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS00245 ^@ http://purl.uniprot.org/uniprot/G7V5G7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the desulfoferrodoxin family.|||Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.|||Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity. http://togogenome.org/gene/580340:TLIE_RS02395 ^@ http://purl.uniprot.org/uniprot/G7V7W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/580340:TLIE_RS05085 ^@ http://purl.uniprot.org/uniprot/G7VA19 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/580340:TLIE_RS08265 ^@ http://purl.uniprot.org/uniprot/G7V7R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS04850 ^@ http://purl.uniprot.org/uniprot/G7V9X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS07770 ^@ http://purl.uniprot.org/uniprot/G7V7A7 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/580340:TLIE_RS01845 ^@ http://purl.uniprot.org/uniprot/G7V771 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/580340:TLIE_RS05465 ^@ http://purl.uniprot.org/uniprot/G7VA96 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/580340:TLIE_RS04130 ^@ http://purl.uniprot.org/uniprot/G7V9I8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/580340:TLIE_RS04270 ^@ http://purl.uniprot.org/uniprot/G7V9L7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/580340:TLIE_RS06115 ^@ http://purl.uniprot.org/uniprot/G7V5D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS08130 ^@ http://purl.uniprot.org/uniprot/G7V7N7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS05200 ^@ http://purl.uniprot.org/uniprot/G7VA42 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/580340:TLIE_RS08340 ^@ http://purl.uniprot.org/uniprot/G7V7T2 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/580340:TLIE_RS06895 ^@ http://purl.uniprot.org/uniprot/G7V674 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS02560 ^@ http://purl.uniprot.org/uniprot/G7V7Z9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS00730 ^@ http://purl.uniprot.org/uniprot/G7V5Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/580340:TLIE_RS08045 ^@ http://purl.uniprot.org/uniprot/G7V7F8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS00130 ^@ http://purl.uniprot.org/uniprot/G7V5E4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08770 ^@ http://purl.uniprot.org/uniprot/G7V890 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS04710 ^@ http://purl.uniprot.org/uniprot/G7V9U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/580340:TLIE_RS06255 ^@ http://purl.uniprot.org/uniprot/G7V5M8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS02280 ^@ http://purl.uniprot.org/uniprot/G7V7M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP I family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05900 ^@ http://purl.uniprot.org/uniprot/G7V589 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03025 ^@ http://purl.uniprot.org/uniprot/G7V8G1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/580340:TLIE_RS04565 ^@ http://purl.uniprot.org/uniprot/G7V9S1 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/580340:TLIE_RS07690 ^@ http://purl.uniprot.org/uniprot/G7V718 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/580340:TLIE_RS03260 ^@ http://purl.uniprot.org/uniprot/G7V8T0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/580340:TLIE_RS06745 ^@ http://purl.uniprot.org/uniprot/G7V644 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/580340:TLIE_RS04680 ^@ http://purl.uniprot.org/uniprot/G7V9U3 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/580340:TLIE_RS05100 ^@ http://purl.uniprot.org/uniprot/G7VA22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/580340:TLIE_RS06455 ^@ http://purl.uniprot.org/uniprot/G7V5R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS08560 ^@ http://purl.uniprot.org/uniprot/G7V849 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS08280 ^@ http://purl.uniprot.org/uniprot/G7V7R9 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/580340:TLIE_RS01800 ^@ http://purl.uniprot.org/uniprot/G7V762 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/580340:TLIE_RS05940 ^@ http://purl.uniprot.org/uniprot/G7V596 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/580340:TLIE_RS05325 ^@ http://purl.uniprot.org/uniprot/G7VA67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02820 ^@ http://purl.uniprot.org/uniprot/G7V8C1 ^@ Function ^@ Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/580340:TLIE_RS01390 ^@ http://purl.uniprot.org/uniprot/G7V6Q6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/580340:TLIE_RS03420 ^@ http://purl.uniprot.org/uniprot/G7V8W1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS06755 ^@ http://purl.uniprot.org/uniprot/G7V646 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00010 ^@ http://purl.uniprot.org/uniprot/G7V547 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/580340:TLIE_RS02185 ^@ http://purl.uniprot.org/uniprot/G7V7K8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/580340:TLIE_RS03350 ^@ http://purl.uniprot.org/uniprot/G7V8U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS01385 ^@ http://purl.uniprot.org/uniprot/G7V6Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03105 ^@ http://purl.uniprot.org/uniprot/G7V8P9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/580340:TLIE_RS05235 ^@ http://purl.uniprot.org/uniprot/G7VA49 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/580340:TLIE_RS00095 ^@ http://purl.uniprot.org/uniprot/G7V5D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS02960 ^@ http://purl.uniprot.org/uniprot/G7V8E8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS00335 ^@ http://purl.uniprot.org/uniprot/G7V5I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS07540 ^@ http://purl.uniprot.org/uniprot/G7V6Z1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02850 ^@ http://purl.uniprot.org/uniprot/G7V8C7 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/580340:TLIE_RS08700 ^@ http://purl.uniprot.org/uniprot/G7V877 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/580340:TLIE_RS01910 ^@ http://purl.uniprot.org/uniprot/G7V784 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS06000 ^@ http://purl.uniprot.org/uniprot/G7V5A7 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS05210 ^@ http://purl.uniprot.org/uniprot/G7VA44 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/580340:TLIE_RS03655 ^@ http://purl.uniprot.org/uniprot/G7V981 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/580340:TLIE_RS03765 ^@ http://purl.uniprot.org/uniprot/G7V9A1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01485 ^@ http://purl.uniprot.org/uniprot/G7V6S4 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/580340:TLIE_RS05670 ^@ http://purl.uniprot.org/uniprot/G7VAC8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS04880 ^@ http://purl.uniprot.org/uniprot/G7V9X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/580340:TLIE_RS08110 ^@ http://purl.uniprot.org/uniprot/G7V7N3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS02270 ^@ http://purl.uniprot.org/uniprot/G7V7M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/580340:TLIE_RS00270 ^@ http://purl.uniprot.org/uniprot/G7V5H2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/580340:TLIE_RS07250 ^@ http://purl.uniprot.org/uniprot/G7V6L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS09000 ^@ http://purl.uniprot.org/uniprot/G7V8K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05795 ^@ http://purl.uniprot.org/uniprot/G7V569 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/580340:TLIE_RS08970 ^@ http://purl.uniprot.org/uniprot/G7V8K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS08205 ^@ http://purl.uniprot.org/uniprot/G7V7Q1 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/580340:TLIE_RS07130 ^@ http://purl.uniprot.org/uniprot/G7V6J2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/580340:TLIE_RS01690 ^@ http://purl.uniprot.org/uniprot/G7V742 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS00985 ^@ http://purl.uniprot.org/uniprot/G7V6A9 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/580340:TLIE_RS09305 ^@ http://purl.uniprot.org/uniprot/G7V8Z1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/580340:TLIE_RS06620 ^@ http://purl.uniprot.org/uniprot/G7V622 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS09105 ^@ http://purl.uniprot.org/uniprot/G7V8M8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00615 ^@ http://purl.uniprot.org/uniprot/G7V5W1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/580340:TLIE_RS02980 ^@ http://purl.uniprot.org/uniprot/G7V8F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/580340:TLIE_RS05895 ^@ http://purl.uniprot.org/uniprot/G7V588 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/580340:TLIE_RS04775 ^@ http://purl.uniprot.org/uniprot/G7V9W2 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/580340:TLIE_RS04335 ^@ http://purl.uniprot.org/uniprot/G7V9N0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/580340:TLIE_RS03280 ^@ http://purl.uniprot.org/uniprot/G7V8T3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/580340:TLIE_RS01465 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS05375 ^@ http://purl.uniprot.org/uniprot/G7VA78 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS04965 ^@ http://purl.uniprot.org/uniprot/G7V9Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06770 ^@ http://purl.uniprot.org/uniprot/G7V649 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS09880 ^@ http://purl.uniprot.org/uniprot/G7V6Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05460 ^@ http://purl.uniprot.org/uniprot/G7VA95 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/580340:TLIE_RS04020 ^@ http://purl.uniprot.org/uniprot/G7V9G9 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/580340:TLIE_RS08750 ^@ http://purl.uniprot.org/uniprot/G7V886 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS07945 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS07100 ^@ http://purl.uniprot.org/uniprot/G7V6I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/580340:TLIE_RS02855 ^@ http://purl.uniprot.org/uniprot/G7V8C8 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/580340:TLIE_RS07855 ^@ http://purl.uniprot.org/uniprot/G7V7C2 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/580340:TLIE_RS07480 ^@ http://purl.uniprot.org/uniprot/G7V6Y0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS06810 ^@ http://purl.uniprot.org/uniprot/G7V657 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/580340:TLIE_RS05945 ^@ http://purl.uniprot.org/uniprot/G7V597 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/580340:TLIE_RS04365 ^@ http://purl.uniprot.org/uniprot/G7V9N6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03275 ^@ http://purl.uniprot.org/uniprot/G7V8T2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/580340:TLIE_RS07875 ^@ http://purl.uniprot.org/uniprot/G7V7C6 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/580340:TLIE_RS09705 ^@ http://purl.uniprot.org/uniprot/G7V932 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS09515 ^@ http://purl.uniprot.org/uniprot/G7V926 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the THI4 family.|||Homooctamer; tetramer of dimers.|||Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS00200 ^@ http://purl.uniprot.org/uniprot/G7V5F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS07605 ^@ http://purl.uniprot.org/uniprot/G7V703 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/580340:TLIE_RS09270 ^@ http://purl.uniprot.org/uniprot/G7V8Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/580340:TLIE_RS02155 ^@ http://purl.uniprot.org/uniprot/G7V7K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03435 ^@ http://purl.uniprot.org/uniprot/G7V8W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/580340:TLIE_RS01710 ^@ http://purl.uniprot.org/uniprot/G7V745 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/580340:TLIE_RS07915 ^@ http://purl.uniprot.org/uniprot/G7V7D2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/580340:TLIE_RS09600 ^@ http://purl.uniprot.org/uniprot/G7V942 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS03990 ^@ http://purl.uniprot.org/uniprot/G7V9G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS07470 ^@ http://purl.uniprot.org/uniprot/G7V6X8 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/580340:TLIE_RS03475 ^@ http://purl.uniprot.org/uniprot/G7V945 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00210 ^@ http://purl.uniprot.org/uniprot/G7V5G0 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/580340:TLIE_RS07295 ^@ http://purl.uniprot.org/uniprot/G7V6M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/580340:TLIE_RS06420 ^@ http://purl.uniprot.org/uniprot/G7V5Q9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/580340:TLIE_RS04440 ^@ http://purl.uniprot.org/uniprot/G7V9P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/580340:TLIE_RS05355 ^@ http://purl.uniprot.org/uniprot/G7VA74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS05315 ^@ http://purl.uniprot.org/uniprot/G7VA65 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/580340:TLIE_RS00570 ^@ http://purl.uniprot.org/uniprot/G7V5V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/580340:TLIE_RS00375 ^@ http://purl.uniprot.org/uniprot/G7V5J2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/580340:TLIE_RS04605 ^@ http://purl.uniprot.org/uniprot/G7V9S8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05170 ^@ http://purl.uniprot.org/uniprot/G7VA36 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/580340:TLIE_RS02190 ^@ http://purl.uniprot.org/uniprot/G7V7K9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/580340:TLIE_RS05270 ^@ http://purl.uniprot.org/uniprot/G7VA56 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS02735 ^@ http://purl.uniprot.org/uniprot/G7V8A7 ^@ Similarity ^@ Belongs to the peptidase T1B family. HslV subfamily. http://togogenome.org/gene/580340:TLIE_RS02030 ^@ http://purl.uniprot.org/uniprot/G7V7I0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS02485 ^@ http://purl.uniprot.org/uniprot/G7V7Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS04985 ^@ http://purl.uniprot.org/uniprot/G7V9Z9 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/580340:TLIE_RS00830 ^@ http://purl.uniprot.org/uniprot/G7V603 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/580340:TLIE_RS03495 ^@ http://purl.uniprot.org/uniprot/G7V949 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS06875 ^@ http://purl.uniprot.org/uniprot/G7V670 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS08920 ^@ http://purl.uniprot.org/uniprot/G7V8J0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS03400 ^@ http://purl.uniprot.org/uniprot/G7V8V7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/580340:TLIE_RS00135 ^@ http://purl.uniprot.org/uniprot/G7V5E5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS05685 ^@ http://purl.uniprot.org/uniprot/G7VAD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS00915 ^@ http://purl.uniprot.org/uniprot/G7V696 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/580340:TLIE_RS01210 ^@ http://purl.uniprot.org/uniprot/G7V6F0 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/580340:TLIE_RS07990 ^@ http://purl.uniprot.org/uniprot/G7V7E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS02765 ^@ http://purl.uniprot.org/uniprot/G7V8B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03325 ^@ http://purl.uniprot.org/uniprot/G7V8U2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/580340:TLIE_RS04325 ^@ http://purl.uniprot.org/uniprot/G7V9M8 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS08765 ^@ http://purl.uniprot.org/uniprot/G7V889 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/580340:TLIE_RS06720 ^@ http://purl.uniprot.org/uniprot/G7V639 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/580340:TLIE_RS09815 ^@ http://purl.uniprot.org/uniprot/G7VAG7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS05720 ^@ http://purl.uniprot.org/uniprot/G7VAD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/580340:TLIE_RS04590 ^@ http://purl.uniprot.org/uniprot/G7V9S5 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/580340:TLIE_RS04310 ^@ http://purl.uniprot.org/uniprot/G7V9M5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/580340:TLIE_RS00940 ^@ http://purl.uniprot.org/uniprot/G7V6A1 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/580340:TLIE_RS06855 ^@ http://purl.uniprot.org/uniprot/G7V666 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/580340:TLIE_RS01795 ^@ http://purl.uniprot.org/uniprot/G7V761 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/580340:TLIE_RS02840 ^@ http://purl.uniprot.org/uniprot/G7V8C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00820 ^@ http://purl.uniprot.org/uniprot/G7V601 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS05595 ^@ http://purl.uniprot.org/uniprot/G7VAB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/580340:TLIE_RS00145 ^@ http://purl.uniprot.org/uniprot/G7V5E7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS00380 ^@ http://purl.uniprot.org/uniprot/G7V5J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/580340:TLIE_RS02240 ^@ http://purl.uniprot.org/uniprot/G7V7L6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/580340:TLIE_RS07730 ^@ http://purl.uniprot.org/uniprot/G7V799 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/580340:TLIE_RS03235 ^@ http://purl.uniprot.org/uniprot/G7V8S5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/580340:TLIE_RS04150 ^@ http://purl.uniprot.org/uniprot/G7V9J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS03115 ^@ http://purl.uniprot.org/uniprot/G7V8Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/580340:TLIE_RS00980 ^@ http://purl.uniprot.org/uniprot/G7V6A8 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/580340:TLIE_RS07210 ^@ http://purl.uniprot.org/uniprot/G7V6K3 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/580340:TLIE_RS01255 ^@ http://purl.uniprot.org/uniprot/G7V6M9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/580340:TLIE_RS03555 ^@ http://purl.uniprot.org/uniprot/G7V961 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/580340:TLIE_RS02835 ^@ http://purl.uniprot.org/uniprot/G7V8C4 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/580340:TLIE_RS02880 ^@ http://purl.uniprot.org/uniprot/G7V8D3 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/580340:TLIE_RS03405 ^@ http://purl.uniprot.org/uniprot/G7V8V8 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS00470 ^@ http://purl.uniprot.org/uniprot/G7V5T2 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/580340:TLIE_RS01985 ^@ http://purl.uniprot.org/uniprot/G7V7H1 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/580340:TLIE_RS05740 ^@ http://purl.uniprot.org/uniprot/G7VAE2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/580340:TLIE_RS00745 ^@ http://purl.uniprot.org/uniprot/G7V5Y6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS07740 ^@ http://purl.uniprot.org/uniprot/G7V7A1 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/580340:TLIE_RS01580 ^@ http://purl.uniprot.org/uniprot/G7V6U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS09190 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS05860 ^@ http://purl.uniprot.org/uniprot/G7V582 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS02455 ^@ http://purl.uniprot.org/uniprot/G7V7X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06205 ^@ http://purl.uniprot.org/uniprot/G7V5L8 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/580340:TLIE_RS04260 ^@ http://purl.uniprot.org/uniprot/G7V9L5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/580340:TLIE_RS02870 ^@ http://purl.uniprot.org/uniprot/G7V8D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00105 ^@ http://purl.uniprot.org/uniprot/G7V5D9 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/580340:TLIE_RS02740 ^@ http://purl.uniprot.org/uniprot/G7V8A8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS06775 ^@ http://purl.uniprot.org/uniprot/G7V650 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/580340:TLIE_RS07810 ^@ http://purl.uniprot.org/uniprot/G7V7B4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/580340:TLIE_RS05215 ^@ http://purl.uniprot.org/uniprot/G7VA45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/580340:TLIE_RS05260 ^@ http://purl.uniprot.org/uniprot/G7VA54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05400 ^@ http://purl.uniprot.org/uniprot/G7VA83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS07520 ^@ http://purl.uniprot.org/uniprot/G7V6Y8 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/580340:TLIE_RS00565 ^@ http://purl.uniprot.org/uniprot/G7V5V1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/580340:TLIE_RS08960 ^@ http://purl.uniprot.org/uniprot/G7V8J8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/580340:TLIE_RS07280 ^@ http://purl.uniprot.org/uniprot/G7V6L7 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/580340:TLIE_RS00205 ^@ http://purl.uniprot.org/uniprot/G7V5F9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/580340:TLIE_RS05425 ^@ http://purl.uniprot.org/uniprot/G7VA88 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03855 ^@ http://purl.uniprot.org/uniprot/G7V9D7 ^@ Similarity|||Subunit ^@ Belongs to the MtrB family.|||Oligomer of 11 identical subunits arranged in doughnut-like structure. http://togogenome.org/gene/580340:TLIE_RS01475 ^@ http://purl.uniprot.org/uniprot/G7V6S2 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/580340:TLIE_RS02235 ^@ http://purl.uniprot.org/uniprot/G7V7L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/580340:TLIE_RS01025 ^@ http://purl.uniprot.org/uniprot/G7V6B7 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/580340:TLIE_RS07955 ^@ http://purl.uniprot.org/uniprot/G7V7E0 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/580340:TLIE_RS01730 ^@ http://purl.uniprot.org/uniprot/G7V748 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04460 ^@ http://purl.uniprot.org/uniprot/G7V9Q0 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/580340:TLIE_RS05065 ^@ http://purl.uniprot.org/uniprot/G7VA15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/580340:TLIE_RS06995 ^@ http://purl.uniprot.org/uniprot/G7V6G6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/580340:TLIE_RS08455 ^@ http://purl.uniprot.org/uniprot/G7V7V5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/580340:TLIE_RS01760 ^@ http://purl.uniprot.org/uniprot/G7V754 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS03930 ^@ http://purl.uniprot.org/uniprot/G7V9F1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/580340:TLIE_RS08440 ^@ http://purl.uniprot.org/uniprot/G7V7V2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS00755 ^@ http://purl.uniprot.org/uniprot/G7V5Y8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/580340:TLIE_RS08605 ^@ http://purl.uniprot.org/uniprot/G7V858 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05935 ^@ http://purl.uniprot.org/uniprot/G7V595 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/580340:TLIE_RS07385 ^@ http://purl.uniprot.org/uniprot/G7V6W1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/580340:TLIE_RS09755 ^@ http://purl.uniprot.org/uniprot/G7VAF6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/580340:TLIE_RS01250 ^@ http://purl.uniprot.org/uniprot/G7V6M8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/580340:TLIE_RS08270 ^@ http://purl.uniprot.org/uniprot/G7V7R7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/580340:TLIE_RS05815 ^@ http://purl.uniprot.org/uniprot/G7V573 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/580340:TLIE_RS06275 ^@ http://purl.uniprot.org/uniprot/G7V5N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS09135 ^@ http://purl.uniprot.org/uniprot/G7V8N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS06445 ^@ http://purl.uniprot.org/uniprot/G7V5R4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/580340:TLIE_RS00575 ^@ http://purl.uniprot.org/uniprot/G7V5V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family. http://togogenome.org/gene/580340:TLIE_RS00990 ^@ http://purl.uniprot.org/uniprot/G7V6B0 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/580340:TLIE_RS02440 ^@ http://purl.uniprot.org/uniprot/G7V7X5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS06495 ^@ http://purl.uniprot.org/uniprot/G7V5S4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/580340:TLIE_RS05640 ^@ http://purl.uniprot.org/uniprot/G7VAC2 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS05020 ^@ http://purl.uniprot.org/uniprot/G7VA06 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS07065 ^@ http://purl.uniprot.org/uniprot/G7V6I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05395 ^@ http://purl.uniprot.org/uniprot/G7VA82 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS08660 ^@ http://purl.uniprot.org/uniprot/G7V869 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/580340:TLIE_RS05965 ^@ http://purl.uniprot.org/uniprot/G7V5A1 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/580340:TLIE_RS06075 ^@ http://purl.uniprot.org/uniprot/G7V5C3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/580340:TLIE_RS00460 ^@ http://purl.uniprot.org/uniprot/G7V5K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/580340:TLIE_RS03330 ^@ http://purl.uniprot.org/uniprot/G7V8U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/580340:TLIE_RS03820 ^@ http://purl.uniprot.org/uniprot/G7V9B1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/580340:TLIE_RS03425 ^@ http://purl.uniprot.org/uniprot/G7V8W2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/580340:TLIE_RS04245 ^@ http://purl.uniprot.org/uniprot/G7V9L2 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/580340:TLIE_RS09795 ^@ http://purl.uniprot.org/uniprot/G7VAG4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/580340:TLIE_RS05440 ^@ http://purl.uniprot.org/uniprot/G7VA91 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the LacAB/RpiB family.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/580340:TLIE_RS03130 ^@ http://purl.uniprot.org/uniprot/G7V8Q4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/580340:TLIE_RS09450 ^@ http://purl.uniprot.org/uniprot/G7V914 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS03750 ^@ http://purl.uniprot.org/uniprot/G7V998 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/580340:TLIE_RS02265 ^@ http://purl.uniprot.org/uniprot/G7V7M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/580340:TLIE_RS02710 ^@ http://purl.uniprot.org/uniprot/G7V828 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/580340:TLIE_RS03795 ^@ http://purl.uniprot.org/uniprot/G7V9A6 ^@ Function|||Similarity|||Subunit ^@ Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.|||Belongs to the HutP family.|||Homohexamer. http://togogenome.org/gene/580340:TLIE_RS07390 ^@ http://purl.uniprot.org/uniprot/G7V6W2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/580340:TLIE_RS03705 ^@ http://purl.uniprot.org/uniprot/G7V988 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/580340:TLIE_RS05190 ^@ http://purl.uniprot.org/uniprot/G7VA40 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/580340:TLIE_RS03065 ^@ http://purl.uniprot.org/uniprot/G7V8G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03390 ^@ http://purl.uniprot.org/uniprot/G7V8V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/580340:TLIE_RS00405 ^@ http://purl.uniprot.org/uniprot/G7V5J8 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/580340:TLIE_RS04500 ^@ http://purl.uniprot.org/uniprot/G7V9Q8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/580340:TLIE_RS05000 ^@ http://purl.uniprot.org/uniprot/G7VA02 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/580340:TLIE_RS06350 ^@ http://purl.uniprot.org/uniprot/G7V5P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/580340:TLIE_RS08065 ^@ http://purl.uniprot.org/uniprot/G7V7G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS02255 ^@ http://purl.uniprot.org/uniprot/G7V7L8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/580340:TLIE_RS05885 ^@ http://purl.uniprot.org/uniprot/G7V586 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/580340:TLIE_RS04175 ^@ http://purl.uniprot.org/uniprot/G7V9J7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/580340:TLIE_RS10095 ^@ http://purl.uniprot.org/uniprot/G7V8N8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/580340:TLIE_RS00525 ^@ http://purl.uniprot.org/uniprot/G7V5U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS05025 ^@ http://purl.uniprot.org/uniprot/G7VA07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/580340:TLIE_RS09935 ^@ http://purl.uniprot.org/uniprot/G7V8R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/580340:TLIE_RS09430 ^@ http://purl.uniprot.org/uniprot/G7V910 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/580340:TLIE_RS04000 ^@ http://purl.uniprot.org/uniprot/G7V9G5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/580340:TLIE_RS06650 ^@ http://purl.uniprot.org/uniprot/G7V628 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS02590 ^@ http://purl.uniprot.org/uniprot/G7V805 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/580340:TLIE_RS09275 ^@ http://purl.uniprot.org/uniprot/G7V8Y6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/580340:TLIE_RS07185 ^@ http://purl.uniprot.org/uniprot/G7V6J9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/580340:TLIE_RS06050 ^@ http://purl.uniprot.org/uniprot/G7V5B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/580340:TLIE_RS05135 ^@ http://purl.uniprot.org/uniprot/G7VA29 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS06480 ^@ http://purl.uniprot.org/uniprot/G7V5S1 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/580340:TLIE_RS04800 ^@ http://purl.uniprot.org/uniprot/G7V9W6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/580340:TLIE_RS06210 ^@ http://purl.uniprot.org/uniprot/G7V5L9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/580340:TLIE_RS02475 ^@ http://purl.uniprot.org/uniprot/G7V7Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS07205 ^@ http://purl.uniprot.org/uniprot/G7V6K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03315 ^@ http://purl.uniprot.org/uniprot/G7V8U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/580340:TLIE_RS05575 ^@ http://purl.uniprot.org/uniprot/G7VAA9 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/580340:TLIE_RS01350 ^@ http://purl.uniprot.org/uniprot/G7V6P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/580340:TLIE_RS08465 ^@ http://purl.uniprot.org/uniprot/G7V830 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS01770 ^@ http://purl.uniprot.org/uniprot/G7V756 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/580340:TLIE_RS00045 ^@ http://purl.uniprot.org/uniprot/G7V554 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS05420 ^@ http://purl.uniprot.org/uniprot/G7VA87 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS05390 ^@ http://purl.uniprot.org/uniprot/G7VA81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS03985 ^@ http://purl.uniprot.org/uniprot/G7V9G2 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/580340:TLIE_RS04360 ^@ http://purl.uniprot.org/uniprot/G7V9N5 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/580340:TLIE_RS06590 ^@ http://purl.uniprot.org/uniprot/G7V616 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/580340:TLIE_RS04160 ^@ http://purl.uniprot.org/uniprot/G7V9J4 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/580340:TLIE_RS02745 ^@ http://purl.uniprot.org/uniprot/G7V8A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/580340:TLIE_RS10065 ^@ http://purl.uniprot.org/uniprot/G7V7U0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/580340:TLIE_RS06025 ^@ http://purl.uniprot.org/uniprot/G7V5B2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/580340:TLIE_RS05655 ^@ http://purl.uniprot.org/uniprot/G7VAC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS09505 ^@ http://purl.uniprot.org/uniprot/G7V924 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04640 ^@ http://purl.uniprot.org/uniprot/G7V9T5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/580340:TLIE_RS06860 ^@ http://purl.uniprot.org/uniprot/G7V667 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS09615 ^@ http://purl.uniprot.org/uniprot/G7V9B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/580340:TLIE_RS02540 ^@ http://purl.uniprot.org/uniprot/G7V7Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS08800 ^@ http://purl.uniprot.org/uniprot/G7V896 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/580340:TLIE_RS05350 ^@ http://purl.uniprot.org/uniprot/G7VA72 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/580340:TLIE_RS03320 ^@ http://purl.uniprot.org/uniprot/G7V8U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/580340:TLIE_RS08905 ^@ http://purl.uniprot.org/uniprot/G7V8I7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/580340:TLIE_RS08910 ^@ http://purl.uniprot.org/uniprot/G7V8I8 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/580340:TLIE_RS09555 ^@ http://purl.uniprot.org/uniprot/G7V934 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/580340:TLIE_RS07395 ^@ http://purl.uniprot.org/uniprot/G7V6W3 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/580340:TLIE_RS03075 ^@ http://purl.uniprot.org/uniprot/G7V8H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/580340:TLIE_RS02825 ^@ http://purl.uniprot.org/uniprot/G7V8C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/580340:TLIE_RS05560 ^@ http://purl.uniprot.org/uniprot/G7VAA6 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/580340:TLIE_RS01960 ^@ http://purl.uniprot.org/uniprot/G7V794 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/580340:TLIE_RS06915 ^@ http://purl.uniprot.org/uniprot/G7V678 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS00155 ^@ http://purl.uniprot.org/uniprot/G7V5E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS04250 ^@ http://purl.uniprot.org/uniprot/G7V9L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/580340:TLIE_RS03890 ^@ http://purl.uniprot.org/uniprot/G7V9E4 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/580340:TLIE_RS03040 ^@ http://purl.uniprot.org/uniprot/G7V8G4 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/580340:TLIE_RS01230 ^@ http://purl.uniprot.org/uniprot/G7V679 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/580340:TLIE_RS03170 ^@ http://purl.uniprot.org/uniprot/G7V8R2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS09130 ^@ http://purl.uniprot.org/uniprot/G7V8N3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/580340:TLIE_RS04995 ^@ http://purl.uniprot.org/uniprot/G7VA01 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/580340:TLIE_RS05145 ^@ http://purl.uniprot.org/uniprot/G7VA31 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/580340:TLIE_RS00880 ^@ http://purl.uniprot.org/uniprot/G7V689 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS09385 ^@ http://purl.uniprot.org/uniprot/G7V903 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/580340:TLIE_RS06470 ^@ http://purl.uniprot.org/uniprot/G7V5R9 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/580340:TLIE_RS00015 ^@ http://purl.uniprot.org/uniprot/G7V548 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/580340:TLIE_RS07710 ^@ http://purl.uniprot.org/uniprot/G7V722 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/580340:TLIE_RS03265 ^@ http://purl.uniprot.org/uniprot/G7V8T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/580340:TLIE_RS09625 ^@ http://purl.uniprot.org/uniprot/G7V9C1 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/580340:TLIE_RS00240 ^@ http://purl.uniprot.org/uniprot/G7V5G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/580340:TLIE_RS06710 ^@ http://purl.uniprot.org/uniprot/G7V637 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS02875 ^@ http://purl.uniprot.org/uniprot/G7V8D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/580340:TLIE_RS09315 ^@ http://purl.uniprot.org/uniprot/G7V8Z3 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/580340:TLIE_RS04615 ^@ http://purl.uniprot.org/uniprot/G7V9T0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/580340:TLIE_RS06220 ^@ http://purl.uniprot.org/uniprot/G7V5M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/580340:TLIE_RS06060 ^@ http://purl.uniprot.org/uniprot/G7V5C0 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/580340:TLIE_RS01855 ^@ http://purl.uniprot.org/uniprot/G7V773 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS03870 ^@ http://purl.uniprot.org/uniprot/G7V9E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/580340:TLIE_RS09745 ^@ http://purl.uniprot.org/uniprot/G7VAF4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/580340:TLIE_RS06360 ^@ http://purl.uniprot.org/uniprot/G7V5P7 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/580340:TLIE_RS08880 ^@ http://purl.uniprot.org/uniprot/G7V8I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/580340:TLIE_RS09220 ^@ http://purl.uniprot.org/uniprot/G7V8X6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/580340:TLIE_RS00540 ^@ http://purl.uniprot.org/uniprot/G7V5U6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/580340:TLIE_RS00400 ^@ http://purl.uniprot.org/uniprot/G7V5J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/580340:TLIE_RS06040 ^@ http://purl.uniprot.org/uniprot/G7V5B5 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/580340:TLIE_RS07940 ^@ http://purl.uniprot.org/uniprot/G7V7D7 ^@ Caution|||Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/580340:TLIE_RS00250 ^@ http://purl.uniprot.org/uniprot/G7V5G8 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.