http://togogenome.org/gene/5861:PY17X_1013500 ^@ http://purl.uniprot.org/uniprot/A0A078KEW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1337600 ^@ http://purl.uniprot.org/uniprot/A0A078KGZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/5861:PY17X_0715000 ^@ http://purl.uniprot.org/uniprot/A0A078K2Q0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0211600 ^@ http://purl.uniprot.org/uniprot/A0A077Y0G3 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/5861:PY17X_1007500 ^@ http://purl.uniprot.org/uniprot/A0A077YEJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Mitochondrion|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/5861:PY17X_1418600 ^@ http://purl.uniprot.org/uniprot/A0A077YBI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/5861:PY17X_1230000 ^@ http://purl.uniprot.org/uniprot/A0A077Y7P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus http://togogenome.org/gene/5861:PY17X_1135100 ^@ http://purl.uniprot.org/uniprot/A0A078KCU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1407500 ^@ http://purl.uniprot.org/uniprot/A0A078KBE4 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_1461800 ^@ http://purl.uniprot.org/uniprot/A0A078K9W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0409200 ^@ http://purl.uniprot.org/uniprot/A0A077Y275 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/5861:PY17X_0935700 ^@ http://purl.uniprot.org/uniprot/A0A077Y535 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/5861:PY17X_0104600 ^@ http://purl.uniprot.org/uniprot/A0A078K2W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/5861:PY17X_1417300 ^@ http://purl.uniprot.org/uniprot/A0A077YCQ0 ^@ Function|||Similarity|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex. http://togogenome.org/gene/5861:PY17X_0810300 ^@ http://purl.uniprot.org/uniprot/A0A078K949 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/5861:PY17X_1127600 ^@ http://purl.uniprot.org/uniprot/A0A077Y687 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1425700 ^@ http://purl.uniprot.org/uniprot/A0A078KFA9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. http://togogenome.org/gene/5861:PY17X_1323600 ^@ http://purl.uniprot.org/uniprot/A0A078KGI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SHMT family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0316500 ^@ http://purl.uniprot.org/uniprot/A0A077XZP3 ^@ Similarity ^@ Belongs to the RAMP4 family. http://togogenome.org/gene/5861:PY17X_0205700 ^@ http://purl.uniprot.org/uniprot/A0A077XZP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/5861:PY17X_1237300 ^@ http://purl.uniprot.org/uniprot/A0A077Y816 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/5861:PY17X_1336700 ^@ http://purl.uniprot.org/uniprot/A0A078KKY5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0112800 ^@ http://purl.uniprot.org/uniprot/A0A077XZA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.|||Involved in the biogenesis of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/5861:PY17X_0927200 ^@ http://purl.uniprot.org/uniprot/A0A077Y4V0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/5861:PY17X_1344900 ^@ http://purl.uniprot.org/uniprot/A0A077YD21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/5861:PY17X_0315200 ^@ http://purl.uniprot.org/uniprot/A0A078K457 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/5861:PY17X_0619900 ^@ http://purl.uniprot.org/uniprot/A0A078KAL2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/5861:PY17X_1026200 ^@ http://purl.uniprot.org/uniprot/A0A078KCL2 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_0316600 ^@ http://purl.uniprot.org/uniprot/A0A078K6W2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/5861:PY17X_1102700 ^@ http://purl.uniprot.org/uniprot/A0A077Y5Q4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat HIR1 family.|||Nucleus|||Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle. http://togogenome.org/gene/5861:PY17X_1323000 ^@ http://purl.uniprot.org/uniprot/A0A077Y9J6 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/5861:PY17X_1433600 ^@ http://purl.uniprot.org/uniprot/A0A077YBZ0 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/5861:PY17X_1124300 ^@ http://purl.uniprot.org/uniprot/A0A078K963 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/5861:PY17X_1120200 ^@ http://purl.uniprot.org/uniprot/A0A078KC50 ^@ Similarity ^@ Belongs to the SF3A2 family. http://togogenome.org/gene/5861:PY17X_0604800 ^@ http://purl.uniprot.org/uniprot/A0A077Y2J4 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/5861:PY17X_0108700 ^@ http://purl.uniprot.org/uniprot/A0A077XZT8 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/5861:PY17X_1424700 ^@ http://purl.uniprot.org/uniprot/A0A077YBF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Cytoplasm|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/5861:PY17X_0917200 ^@ http://purl.uniprot.org/uniprot/A0A078K7F4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/5861:PY17X_1339300 ^@ http://purl.uniprot.org/uniprot/A0A078KKT2 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/5861:PY17X_1246200 ^@ http://purl.uniprot.org/uniprot/A0A077Y945 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1037900 ^@ http://purl.uniprot.org/uniprot/A0A078KFN6 ^@ Similarity ^@ Belongs to the VPS29 family. http://togogenome.org/gene/5861:PY17X_1035000 ^@ http://purl.uniprot.org/uniprot/A0A077YFD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/5861:PY17X_0306300 ^@ http://purl.uniprot.org/uniprot/A0A078K6N3 ^@ Similarity ^@ Belongs to the RRF family. http://togogenome.org/gene/5861:PY17X_1305500 ^@ http://purl.uniprot.org/uniprot/A0A077Y8I6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0924900 ^@ http://purl.uniprot.org/uniprot/A0A4V0KL67 ^@ Similarity ^@ Belongs to the Tim44 family. http://togogenome.org/gene/5861:PY17X_1435300 ^@ http://purl.uniprot.org/uniprot/A0A078KFL7 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. http://togogenome.org/gene/5861:PY17X_1145800 ^@ http://purl.uniprot.org/uniprot/A0A077Y7S2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/5861:PY17X_0510900 ^@ http://purl.uniprot.org/uniprot/A0A078K586 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/5861:PY17X_0109000 ^@ http://purl.uniprot.org/uniprot/A0A077XYA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0825000 ^@ http://purl.uniprot.org/uniprot/A0A078K6H9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/5861:PY17X_0812400 ^@ http://purl.uniprot.org/uniprot/A0A078K373 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/5861:PY17X_1344800 ^@ http://purl.uniprot.org/uniprot/A0A077Y9S7 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/5861:PY17X_0414900 ^@ http://purl.uniprot.org/uniprot/A0A078K7C6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/5861:PY17X_0916500 ^@ http://purl.uniprot.org/uniprot/A0A078KAI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_1016300 ^@ http://purl.uniprot.org/uniprot/A0A077YH97 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/5861:PY17X_1210100 ^@ http://purl.uniprot.org/uniprot/A0A078K9Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5861:PY17X_1411600 ^@ http://purl.uniprot.org/uniprot/A0A077YBA8 ^@ Similarity|||Subunit ^@ Belongs to the ATPase gamma chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. http://togogenome.org/gene/5861:PY17X_1330200 ^@ http://purl.uniprot.org/uniprot/A0A078KKR9 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/5861:PY17X_1459400 ^@ http://purl.uniprot.org/uniprot/A0A077YFQ1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/5861:PY17X_1452600 ^@ http://purl.uniprot.org/uniprot/A0A078KG37 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/5861:PY17X_1438100 ^@ http://purl.uniprot.org/uniprot/A0A077YF48 ^@ Function|||Similarity ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).|||Belongs to the TDD superfamily. TSR3 family. http://togogenome.org/gene/5861:PY17X_1368300 ^@ http://purl.uniprot.org/uniprot/A0A078KLF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/5861:PY17X_1243100 ^@ http://purl.uniprot.org/uniprot/A0A078KEB4 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/5861:PY17X_1018500 ^@ http://purl.uniprot.org/uniprot/A0A078KF04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1325200 ^@ http://purl.uniprot.org/uniprot/A0A078KKL5 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/5861:PY17X_1336200 ^@ http://purl.uniprot.org/uniprot/A0A078KKX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TLS1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1306600 ^@ http://purl.uniprot.org/uniprot/Q86SB2 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5861:PY17X_0524500 ^@ http://purl.uniprot.org/uniprot/A0A4V0KH13 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5861:PY17X_1136600 ^@ http://purl.uniprot.org/uniprot/A0A078KCV3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/5861:PY17X_0311100 ^@ http://purl.uniprot.org/uniprot/A0A077Y1R7 ^@ Similarity ^@ Belongs to the FAM136 family. http://togogenome.org/gene/5861:PY17X_1240500 ^@ http://purl.uniprot.org/uniprot/A0A078KB01 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/5861:PY17X_0312900 ^@ http://purl.uniprot.org/uniprot/A0A078K6B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||apicoplast http://togogenome.org/gene/5861:PY17X_0513000 ^@ http://purl.uniprot.org/uniprot/A0A077Y0U5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/5861:PY17X_1133000 ^@ http://purl.uniprot.org/uniprot/A0A077Y6E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/5861:PY17X_0408600 ^@ http://purl.uniprot.org/uniprot/A0A077Y268 ^@ Similarity ^@ Belongs to the DNA polymerase delta/II small subunit family. http://togogenome.org/gene/5861:PY17X_0808200 ^@ http://purl.uniprot.org/uniprot/A0A078K932 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/5861:PY17X_0924800 ^@ http://purl.uniprot.org/uniprot/A0A078K4M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.|||Nucleus http://togogenome.org/gene/5861:PY17X_0517500 ^@ http://purl.uniprot.org/uniprot/A0A077Y5B4 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/5861:PY17X_1004100 ^@ http://purl.uniprot.org/uniprot/A0A077YGW8 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_1144900 ^@ http://purl.uniprot.org/uniprot/A0A078K9J1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Mitochondrion|||Monomer. http://togogenome.org/gene/5861:PY17X_1239000 ^@ http://purl.uniprot.org/uniprot/A0A078KAY6 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/5861:PY17X_1209300 ^@ http://purl.uniprot.org/uniprot/A0A078KDF0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/5861:PY17X_0215800 ^@ http://purl.uniprot.org/uniprot/A0A078K5Z9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0208600 ^@ http://purl.uniprot.org/uniprot/A0A078K3J4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/5861:PY17X_0307500 ^@ http://purl.uniprot.org/uniprot/A0A077Y0D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5861:PY17X_0822000 ^@ http://purl.uniprot.org/uniprot/A0A078K6E5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/5861:PY17X_0514500 ^@ http://purl.uniprot.org/uniprot/A0A077Y0W0 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/5861:PY17X_0923100 ^@ http://purl.uniprot.org/uniprot/A0A4V0KMC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/5861:PY17X_1412900 ^@ http://purl.uniprot.org/uniprot/A0A077YB02 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/5861:PY17X_1029400 ^@ http://purl.uniprot.org/uniprot/A0A077YGA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1352500 ^@ http://purl.uniprot.org/uniprot/A0A078KLG4 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_1360000 ^@ http://purl.uniprot.org/uniprot/A0A077Y9T0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/5861:PY17X_1015200 ^@ http://purl.uniprot.org/uniprot/A0A077YES8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/5861:PY17X_0606900 ^@ http://purl.uniprot.org/uniprot/A0A077Y3R6 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/5861:PY17X_1111900 ^@ http://purl.uniprot.org/uniprot/A0A077Y5X0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/5861:PY17X_0712800 ^@ http://purl.uniprot.org/uniprot/A0A077Y3H7 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/5861:PY17X_1411400 ^@ http://purl.uniprot.org/uniprot/A0A077YAY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MNS1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0720300 ^@ http://purl.uniprot.org/uniprot/A0A078K900 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0939000 ^@ http://purl.uniprot.org/uniprot/A0A078K880 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/5861:PY17X_1461400 ^@ http://purl.uniprot.org/uniprot/A0A077YCF3 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/5861:PY17X_1431900 ^@ http://purl.uniprot.org/uniprot/A0A4V0KTQ0 ^@ Similarity ^@ Belongs to the eIF-2B gamma/epsilon subunits family. http://togogenome.org/gene/5861:PY17X_0625100 ^@ http://purl.uniprot.org/uniprot/A0A077Y2P9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/5861:PY17X_0605100 ^@ http://purl.uniprot.org/uniprot/A0A077Y1C5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1230900 ^@ http://purl.uniprot.org/uniprot/A0A078KAK6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-2B subfamily. http://togogenome.org/gene/5861:PY17X_1120800 ^@ http://purl.uniprot.org/uniprot/A0A077YA24 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1129200 ^@ http://purl.uniprot.org/uniprot/A0A077YAA8 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/5861:PY17X_0112000 ^@ http://purl.uniprot.org/uniprot/A0A077XYD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1233300 ^@ http://purl.uniprot.org/uniprot/A0A077Y7W2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/5861:PY17X_0103700 ^@ http://purl.uniprot.org/uniprot/A0A078K5G0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1246700 ^@ http://purl.uniprot.org/uniprot/A0A078KB54 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5861:PY17X_1407000 ^@ http://purl.uniprot.org/uniprot/A0A078KBE0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0505200 ^@ http://purl.uniprot.org/uniprot/A0A078K1S8 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/5861:PY17X_0933200 ^@ http://purl.uniprot.org/uniprot/A0A077Y509 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/5861:PY17X_1118100 ^@ http://purl.uniprot.org/uniprot/A0A077Y7U9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5861:PY17X_1036700 ^@ http://purl.uniprot.org/uniprot/A0A078KD02 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1005200 ^@ http://purl.uniprot.org/uniprot/A0A077YF83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/5861:PY17X_1422600 ^@ http://purl.uniprot.org/uniprot/A0A077YBM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1107600 ^@ http://purl.uniprot.org/uniprot/A0A077Y6K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1415900 ^@ http://purl.uniprot.org/uniprot/A0A078KF17 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. http://togogenome.org/gene/5861:PY17X_1325500 ^@ http://purl.uniprot.org/uniprot/A0A077Y9L7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5861:PY17X_0205600 ^@ http://purl.uniprot.org/uniprot/A0A078K3F3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1206200 ^@ http://purl.uniprot.org/uniprot/A0A077Y717 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5861:PY17X_0933300 ^@ http://purl.uniprot.org/uniprot/A0A077Y902 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5861:PY17X_1367700 ^@ http://purl.uniprot.org/uniprot/A0A078KLT7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5861:PY17X_1412200 ^@ http://purl.uniprot.org/uniprot/A0A078KBJ6 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/5861:PY17X_1402700 ^@ http://purl.uniprot.org/uniprot/A0A077YAN9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/5861:PY17X_0931900 ^@ http://purl.uniprot.org/uniprot/A0A078K7S5 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5861:PY17X_1139300 ^@ http://purl.uniprot.org/uniprot/A0A078K6E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/5861:PY17X_1322000 ^@ http://purl.uniprot.org/uniprot/A0A077Y9J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NifU family.|||Mitochondrion matrix|||Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. http://togogenome.org/gene/5861:PY17X_0502300 ^@ http://purl.uniprot.org/uniprot/A0A077Y2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1006900 ^@ http://purl.uniprot.org/uniprot/A0A077YFP8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_1458900 ^@ http://purl.uniprot.org/uniprot/A0A077YFP5 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/5861:PY17X_0618700 ^@ http://purl.uniprot.org/uniprot/A0A077Y440 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/5861:PY17X_1011100 ^@ http://purl.uniprot.org/uniprot/A0A078KIV4 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/5861:PY17X_0619500 ^@ http://purl.uniprot.org/uniprot/A0A078KDT8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5861:PY17X_1213300 ^@ http://purl.uniprot.org/uniprot/A0A077Y932 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/5861:PY17X_0940800 ^@ http://purl.uniprot.org/uniprot/A0A077Y9A8 ^@ Function|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Plays an important role in regulating the size of autophagosomes during the formation process. http://togogenome.org/gene/5861:PY17X_0943700 ^@ http://purl.uniprot.org/uniprot/A0A077Y5C9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/5861:PY17X_1328700 ^@ http://purl.uniprot.org/uniprot/A0A078KKQ3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/5861:PY17X_0806700 ^@ http://purl.uniprot.org/uniprot/A0A078K9F9 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/5861:PY17X_1426800 ^@ http://purl.uniprot.org/uniprot/A0A077YEU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/5861:PY17X_0833000 ^@ http://purl.uniprot.org/uniprot/A0A078K6Q6 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/5861:PY17X_1225700 ^@ http://purl.uniprot.org/uniprot/A0A078KAL0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/5861:PY17X_0403200 ^@ http://purl.uniprot.org/uniprot/A0A077Y4A4 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/5861:PY17X_1024200 ^@ http://purl.uniprot.org/uniprot/A0A078KCI8 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/5861:PY17X_1333000 ^@ http://purl.uniprot.org/uniprot/A0A078KGT3 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_1412000 ^@ http://purl.uniprot.org/uniprot/A0A078K8J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Mitochondrion intermembrane space http://togogenome.org/gene/5861:PY17X_0946300 ^@ http://purl.uniprot.org/uniprot/A0A077Y7E5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/5861:PY17X_1347600 ^@ http://purl.uniprot.org/uniprot/A0A077Y9K2 ^@ Similarity ^@ Belongs to the RENT3 family. http://togogenome.org/gene/5861:PY17X_0718700 ^@ http://purl.uniprot.org/uniprot/A0A078K608 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAF1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1408500 ^@ http://purl.uniprot.org/uniprot/A0A078KBF4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/5861:PY17X_1210200 ^@ http://purl.uniprot.org/uniprot/A0A078KA43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/5861:PY17X_0906500 ^@ http://purl.uniprot.org/uniprot/A0A078K450 ^@ Function|||Similarity ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. http://togogenome.org/gene/5861:PY17X_1109000 ^@ http://purl.uniprot.org/uniprot/A0A077Y9R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1123900 ^@ http://purl.uniprot.org/uniprot/A0A078KCK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BBP/SF1 family.|||Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.|||Nucleus http://togogenome.org/gene/5861:PY17X_0410200 ^@ http://purl.uniprot.org/uniprot/A0A078K782 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/5861:PY17X_1335300 ^@ http://purl.uniprot.org/uniprot/A0A078KKN6 ^@ Similarity ^@ Belongs to the DXR family. http://togogenome.org/gene/5861:PY17X_1318400 ^@ http://purl.uniprot.org/uniprot/A0A077YCC7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/5861:PY17X_1036000 ^@ http://purl.uniprot.org/uniprot/A0A077YFE1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/5861:PY17X_0103600 ^@ http://purl.uniprot.org/uniprot/A0A078K2V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1418300 ^@ http://purl.uniprot.org/uniprot/A0A078KF62 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2Fe2S plant-type ferredoxin family.|||Binds 1 [2Fe-2S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/5861:PY17X_0305900 ^@ http://purl.uniprot.org/uniprot/A0A077Y0R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Component of the ribosomal small subunit (SSU) processome.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.|||nucleolus http://togogenome.org/gene/5861:PY17X_1230700 ^@ http://purl.uniprot.org/uniprot/A0A078KDU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYF2 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0830500 ^@ http://purl.uniprot.org/uniprot/A0A078K6N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_0405200 ^@ http://purl.uniprot.org/uniprot/A0A078K3W4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/5861:PY17X_1018200 ^@ http://purl.uniprot.org/uniprot/A0A078KIS4 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/5861:PY17X_1108700 ^@ http://purl.uniprot.org/uniprot/A0A078K8Q5 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5861:PY17X_1339900 ^@ http://purl.uniprot.org/uniprot/A0A077YCX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0415000 ^@ http://purl.uniprot.org/uniprot/A0A078K726 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5861:PY17X_1361400 ^@ http://purl.uniprot.org/uniprot/A0A078KEW9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/5861:PY17X_1020100 ^@ http://purl.uniprot.org/uniprot/A0A078KJ65 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/5861:PY17X_0518900 ^@ http://purl.uniprot.org/uniprot/A0A078K5G3 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/5861:PY17X_0303100 ^@ http://purl.uniprot.org/uniprot/Q8I756 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/5861:PY17X_1411200 ^@ http://purl.uniprot.org/uniprot/A0A078KBI7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/5861:PY17X_1411500 ^@ http://purl.uniprot.org/uniprot/A0A077YEA6 ^@ Similarity ^@ Belongs to the WD repeat SMU1 family. http://togogenome.org/gene/5861:PY17X_1353500 ^@ http://purl.uniprot.org/uniprot/A0A077YBM9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1466100 ^@ http://purl.uniprot.org/uniprot/A0A078KGN9 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/5861:PY17X_1134800 ^@ http://purl.uniprot.org/uniprot/A0A078K9A3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5861:PY17X_0508500 ^@ http://purl.uniprot.org/uniprot/A0A077Y0Q9 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/5861:PY17X_1127000 ^@ http://purl.uniprot.org/uniprot/A0A077Y682 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/5861:PY17X_1422800 ^@ http://purl.uniprot.org/uniprot/A0A077YCV8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1039000 ^@ http://purl.uniprot.org/uniprot/A0A078KJP8 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/5861:PY17X_0103500 ^@ http://purl.uniprot.org/uniprot/A0A078K264 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1019200 ^@ http://purl.uniprot.org/uniprot/A0A077YF09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRH/QCR6 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_0113400 ^@ http://purl.uniprot.org/uniprot/A0A077Y0P7 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/5861:PY17X_0708600 ^@ http://purl.uniprot.org/uniprot/A0A077Y270 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0215000 ^@ http://purl.uniprot.org/uniprot/A0A077Y3L1 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/5861:PY17X_0824400 ^@ http://purl.uniprot.org/uniprot/A0A077Y7L9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_1111200 ^@ http://purl.uniprot.org/uniprot/A0A077Y5W6 ^@ Similarity ^@ Belongs to the type IB topoisomerase family. http://togogenome.org/gene/5861:PY17X_0912800 ^@ http://purl.uniprot.org/uniprot/A0A077Y6L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_0307800 ^@ http://purl.uniprot.org/uniprot/A0A077Y3V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1206900 ^@ http://purl.uniprot.org/uniprot/A0A078KD49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1211700 ^@ http://purl.uniprot.org/uniprot/A0A078KA59 ^@ Similarity ^@ Belongs to the proteasome inhibitor PI31 family. http://togogenome.org/gene/5861:PY17X_1117700 ^@ http://purl.uniprot.org/uniprot/A0A078KC27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/5861:PY17X_0816100 ^@ http://purl.uniprot.org/uniprot/A0A077Y3K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. LepA subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Mitochondrion inner membrane|||Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. http://togogenome.org/gene/5861:PY17X_1361600 ^@ http://purl.uniprot.org/uniprot/A0A077Y9T8 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/5861:PY17X_1118600 ^@ http://purl.uniprot.org/uniprot/A0A077Y7V5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/5861:PY17X_0503200 ^@ http://purl.uniprot.org/uniprot/A0A077Y1A9 ^@ Similarity ^@ Belongs to the proteasome subunit p55 family. http://togogenome.org/gene/5861:PY17X_0708900 ^@ http://purl.uniprot.org/uniprot/A0A077Y2Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/5861:PY17X_0907800 ^@ http://purl.uniprot.org/uniprot/A0A077Y6G1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/5861:PY17X_0110700 ^@ http://purl.uniprot.org/uniprot/A0A078K5N6 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/5861:PY17X_0614100 ^@ http://purl.uniprot.org/uniprot/A0A077Y1M2 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/5861:PY17X_1330100 ^@ http://purl.uniprot.org/uniprot/A0A077Y8Z0 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 heme c group covalently per subunit.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1357000 ^@ http://purl.uniprot.org/uniprot/A0A077YAI6 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/5861:PY17X_1219800 ^@ http://purl.uniprot.org/uniprot/A0A078KDW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAPT1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_0930500 ^@ http://purl.uniprot.org/uniprot/A0A077Y552 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_1411700 ^@ http://purl.uniprot.org/uniprot/A0A077YAB1 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/5861:PY17X_1032900 ^@ http://purl.uniprot.org/uniprot/A0A078KFF2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1104200 ^@ http://purl.uniprot.org/uniprot/A0A078K8L4 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/5861:PY17X_1422300 ^@ http://purl.uniprot.org/uniprot/A0A077YCV5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5861:PY17X_1143700 ^@ http://purl.uniprot.org/uniprot/A0A077YAS2 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/5861:PY17X_0607100 ^@ http://purl.uniprot.org/uniprot/A0A077Y5P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO4 family.|||Membrane http://togogenome.org/gene/5861:PY17X_0717800 ^@ http://purl.uniprot.org/uniprot/A0A078K8X1 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5861:PY17X_0945800 ^@ http://purl.uniprot.org/uniprot/A0A077Y9F7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5861:PY17X_0504700 ^@ http://purl.uniprot.org/uniprot/A0A077Y1U9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/5861:PY17X_1128000 ^@ http://purl.uniprot.org/uniprot/A0A078KCN3 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/5861:PY17X_1204800 ^@ http://purl.uniprot.org/uniprot/A0A077Y8W2 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/5861:PY17X_0409500 ^@ http://purl.uniprot.org/uniprot/A0A078K4H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0812200 ^@ http://purl.uniprot.org/uniprot/A0A077Y5A2 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/5861:PY17X_1464000 ^@ http://purl.uniprot.org/uniprot/A0A078KCR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_1305700 ^@ http://purl.uniprot.org/uniprot/A0A077Y976 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/5861:PY17X_0938600 ^@ http://purl.uniprot.org/uniprot/A0A078KBH8 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5861:PY17X_1334200 ^@ http://purl.uniprot.org/uniprot/A0A078KKW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PPP phosphatase family. BSU subfamily.|||Nucleus http://togogenome.org/gene/5861:PY17X_1462300 ^@ http://purl.uniprot.org/uniprot/A0A4V0KV69 ^@ Similarity ^@ Belongs to the CWC26 family. http://togogenome.org/gene/5861:PY17X_0904700 ^@ http://purl.uniprot.org/uniprot/A0A078K7E3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. http://togogenome.org/gene/5861:PY17X_0818500 ^@ http://purl.uniprot.org/uniprot/A0A077Y496 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/5861:PY17X_0313800 ^@ http://purl.uniprot.org/uniprot/A0A078K6U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Membrane http://togogenome.org/gene/5861:PY17X_0835900 ^@ http://purl.uniprot.org/uniprot/A0A077Y7Z0 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/5861:PY17X_0917100 ^@ http://purl.uniprot.org/uniprot/A0A078K4H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/5861:PY17X_1348000 ^@ http://purl.uniprot.org/uniprot/A0A077YAC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_0607800 ^@ http://purl.uniprot.org/uniprot/A0A078KD20 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/5861:PY17X_1344600 ^@ http://purl.uniprot.org/uniprot/A0A078KHA0 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/5861:PY17X_0925600 ^@ http://purl.uniprot.org/uniprot/A0A077Y6Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/5861:PY17X_1359300 ^@ http://purl.uniprot.org/uniprot/A0A078KHL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INCENP family.|||Nucleus|||spindle http://togogenome.org/gene/5861:PY17X_0607600 ^@ http://purl.uniprot.org/uniprot/A0A4V0KI07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HOP2 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0617900 ^@ http://purl.uniprot.org/uniprot/A0A4V0KIA2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/5861:PY17X_1011400 ^@ http://purl.uniprot.org/uniprot/A0A078KF77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX15/CtaA family.|||Membrane http://togogenome.org/gene/5861:PY17X_0214600 ^@ http://purl.uniprot.org/uniprot/A0A077Y0J6 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/5861:PY17X_0506200 ^@ http://purl.uniprot.org/uniprot/A0A078K1T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/5861:PY17X_1217100 ^@ http://purl.uniprot.org/uniprot/A0A078KA84 ^@ Similarity ^@ Belongs to the DNA polymerase type-B-like family. http://togogenome.org/gene/5861:PY17X_1033000 ^@ http://purl.uniprot.org/uniprot/A0A078KJG0 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/5861:PY17X_0304200 ^@ http://purl.uniprot.org/uniprot/A0A078K3X3 ^@ Similarity ^@ Belongs to the proteasome subunit S2 family. http://togogenome.org/gene/5861:PY17X_1361200 ^@ http://purl.uniprot.org/uniprot/A0A078KLM3 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/5861:PY17X_0315900 ^@ http://purl.uniprot.org/uniprot/A0A077Y107 ^@ Similarity ^@ Belongs to the SNW family. http://togogenome.org/gene/5861:PY17X_1219300 ^@ http://purl.uniprot.org/uniprot/A0A078KDV8 ^@ Similarity ^@ Belongs to the CDC123 family. http://togogenome.org/gene/5861:PY17X_1144800 ^@ http://purl.uniprot.org/uniprot/A0A077Y7R4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/5861:PY17X_1122500 ^@ http://purl.uniprot.org/uniprot/A0A077Y632 ^@ Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/5861:PY17X_1451400 ^@ http://purl.uniprot.org/uniprot/A0A077YFH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1230500 ^@ http://purl.uniprot.org/uniprot/A0A077Y7P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1235200 ^@ http://purl.uniprot.org/uniprot/A0A078KDY5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/5861:PY17X_0915300 ^@ http://purl.uniprot.org/uniprot/A0A077Y4Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||apicoplast http://togogenome.org/gene/5861:PY17X_0810200 ^@ http://purl.uniprot.org/uniprot/A0A4V6MAH0 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/5861:PY17X_1348600 ^@ http://purl.uniprot.org/uniprot/A0A078KHB0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class III subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion|||NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. http://togogenome.org/gene/5861:PY17X_0934200 ^@ http://purl.uniprot.org/uniprot/A0A078KB05 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5861:PY17X_1359700 ^@ http://purl.uniprot.org/uniprot/A0A078KHK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/5861:PY17X_1357100 ^@ http://purl.uniprot.org/uniprot/A0A078KHK1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/5861:PY17X_1437200 ^@ http://purl.uniprot.org/uniprot/A0A077YC22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/5861:PY17X_0203700 ^@ http://purl.uniprot.org/uniprot/A0A077XZL6 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5861:PY17X_0829800 ^@ http://purl.uniprot.org/uniprot/A0A078K9M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/5861:PY17X_1406600 ^@ http://purl.uniprot.org/uniprot/A0A077YA65 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_0720600 ^@ http://purl.uniprot.org/uniprot/A0A077Y6R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/5861:PY17X_1364800 ^@ http://purl.uniprot.org/uniprot/A0A077YAB7 ^@ Similarity ^@ Belongs to the MOG1 family. http://togogenome.org/gene/5861:PY17X_0817100 ^@ http://purl.uniprot.org/uniprot/A0A078K6L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRM6/GCD10 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1453800 ^@ http://purl.uniprot.org/uniprot/A0A078KCU3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. RsmH family. http://togogenome.org/gene/5861:PY17X_0313600 ^@ http://purl.uniprot.org/uniprot/A0A078K3L1 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/5861:PY17X_1015300 ^@ http://purl.uniprot.org/uniprot/A0A078KC85 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/5861:PY17X_1020000 ^@ http://purl.uniprot.org/uniprot/A0A077YJ94 ^@ Similarity|||Subunit ^@ Belongs to the NAC-beta family.|||Part of the nascent polypeptide-associated complex (NAC). http://togogenome.org/gene/5861:PY17X_1456500 ^@ http://purl.uniprot.org/uniprot/A0A077YCK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/5861:PY17X_1452300 ^@ http://purl.uniprot.org/uniprot/A0A077YC60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_0920500 ^@ http://purl.uniprot.org/uniprot/A0A078K7U4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/5861:PY17X_0813900 ^@ http://purl.uniprot.org/uniprot/A0A078K379 ^@ Similarity ^@ Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. http://togogenome.org/gene/5861:PY17X_1433200 ^@ http://purl.uniprot.org/uniprot/A0A077YB27 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5861:PY17X_1132500 ^@ http://purl.uniprot.org/uniprot/A0A077Y6D7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/5861:PY17X_0621500 ^@ http://purl.uniprot.org/uniprot/A0A078KDV9 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_0707000 ^@ http://purl.uniprot.org/uniprot/A0A077Y4J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5861:PY17X_0614500 ^@ http://purl.uniprot.org/uniprot/A0A078KH45 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/5861:PY17X_0811700 ^@ http://purl.uniprot.org/uniprot/A0A077Y597 ^@ Similarity ^@ Belongs to the TBCB family. http://togogenome.org/gene/5861:PY17X_0826700 ^@ http://purl.uniprot.org/uniprot/A0A077Y5U0 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/5861:PY17X_1205000 ^@ http://purl.uniprot.org/uniprot/A0A077YAY3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/5861:PY17X_0315700 ^@ http://purl.uniprot.org/uniprot/A0A077XZN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/5861:PY17X_1458800 ^@ http://purl.uniprot.org/uniprot/A0A077YCC5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/5861:PY17X_1360900 ^@ http://purl.uniprot.org/uniprot/A0A078KEW6 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/5861:PY17X_0110400 ^@ http://purl.uniprot.org/uniprot/A0A078JZQ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5861:PY17X_1126900 ^@ http://purl.uniprot.org/uniprot/A0A077Y840 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/5861:PY17X_1134900 ^@ http://purl.uniprot.org/uniprot/A0A078K9A3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5861:PY17X_0408800 ^@ http://purl.uniprot.org/uniprot/A0A077Y4G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/5861:PY17X_1446600 ^@ http://purl.uniprot.org/uniprot/A0A077YDG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1032500 ^@ http://purl.uniprot.org/uniprot/A0A078KJF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1326200 ^@ http://purl.uniprot.org/uniprot/A0A078KKM5 ^@ Similarity ^@ Belongs to the EXO5 family. http://togogenome.org/gene/5861:PY17X_0805300 ^@ http://purl.uniprot.org/uniprot/A0A078K910 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/5861:PY17X_0701900 ^@ http://purl.uniprot.org/uniprot/A0A077Y2U5 ^@ Similarity ^@ Belongs to the CCDC124 family. http://togogenome.org/gene/5861:PY17X_0524900 ^@ http://purl.uniprot.org/uniprot/A0A077Y2E8 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/5861:PY17X_0837800 ^@ http://purl.uniprot.org/uniprot/A0A078KA98 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/5861:PY17X_1023700 ^@ http://purl.uniprot.org/uniprot/A0A078KCH9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/5861:PY17X_1109800 ^@ http://purl.uniprot.org/uniprot/A0A077Y7N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1216300 ^@ http://purl.uniprot.org/uniprot/A0A078KDS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1322200 ^@ http://purl.uniprot.org/uniprot/A0A078KKJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/5861:PY17X_1130800 ^@ http://purl.uniprot.org/uniprot/A0A077Y6C6 ^@ Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM188 subfamily. http://togogenome.org/gene/5861:PY17X_1309700 ^@ http://purl.uniprot.org/uniprot/A0A078KDE8 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/5861:PY17X_0419800 ^@ http://purl.uniprot.org/uniprot/A0A077Y4S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1463600 ^@ http://purl.uniprot.org/uniprot/A0A078KGK2 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/5861:PY17X_1118200 ^@ http://purl.uniprot.org/uniprot/A0A077Y5Z2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5861:PY17X_0309700 ^@ http://purl.uniprot.org/uniprot/A0A077XZH5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/5861:PY17X_1133400 ^@ http://purl.uniprot.org/uniprot/A0A078K991 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. http://togogenome.org/gene/5861:PY17X_1352600 ^@ http://purl.uniprot.org/uniprot/A0A077YA25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/5861:PY17X_1013900 ^@ http://purl.uniprot.org/uniprot/A0A078KFA2 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/5861:PY17X_0404500 ^@ http://purl.uniprot.org/uniprot/A0A078K6P5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/5861:PY17X_1353400 ^@ http://purl.uniprot.org/uniprot/A0A078KHH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H3 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1010400 ^@ http://purl.uniprot.org/uniprot/A0A078KF65 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/5861:PY17X_0709000 ^@ http://purl.uniprot.org/uniprot/A0A078K2K5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/5861:PY17X_1131800 ^@ http://purl.uniprot.org/uniprot/A0A4V0KP29 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/5861:PY17X_1234200 ^@ http://purl.uniprot.org/uniprot/A0A078KDX7 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/5861:PY17X_1448000 ^@ http://purl.uniprot.org/uniprot/A0A078KG12 ^@ Similarity ^@ Belongs to the fl(2)d family. http://togogenome.org/gene/5861:PY17X_1115400 ^@ http://purl.uniprot.org/uniprot/A0A078K8U6 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/5861:PY17X_1441200 ^@ http://purl.uniprot.org/uniprot/A0A078K9B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5861:PY17X_1210400 ^@ http://purl.uniprot.org/uniprot/A0A077Y785 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5861:PY17X_1457700 ^@ http://purl.uniprot.org/uniprot/A0A077YDT6 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5861:PY17X_1216700 ^@ http://purl.uniprot.org/uniprot/A0A078KAC6 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/5861:PY17X_0826400 ^@ http://purl.uniprot.org/uniprot/A0A078K3F7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/5861:PY17X_1307500 ^@ http://purl.uniprot.org/uniprot/A0A077Y8E3 ^@ Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. http://togogenome.org/gene/5861:PY17X_1110100 ^@ http://purl.uniprot.org/uniprot/A0A077Y6M8 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/5861:PY17X_1041800 ^@ http://purl.uniprot.org/uniprot/A0A077YJW0 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/5861:PY17X_0303300 ^@ http://purl.uniprot.org/uniprot/A0A077Y3Q4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1011800 ^@ http://purl.uniprot.org/uniprot/A0A077YH48 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1222700 ^@ http://purl.uniprot.org/uniprot/A0A077Y7I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CRT-like transporter family.|||May regulate endogenous transporter.|||Membrane|||Vacuole membrane http://togogenome.org/gene/5861:PY17X_1042300 ^@ http://purl.uniprot.org/uniprot/A0A078KD48 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/5861:PY17X_0924100 ^@ http://purl.uniprot.org/uniprot/A0A078KB66 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/5861:PY17X_1133500 ^@ http://purl.uniprot.org/uniprot/A0A078K9E6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0104100 ^@ http://purl.uniprot.org/uniprot/A0A077XZQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Mitochondrion matrix http://togogenome.org/gene/5861:PY17X_0919400 ^@ http://purl.uniprot.org/uniprot/A0A077Y6R5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_0838600 ^@ http://purl.uniprot.org/uniprot/A0A077Y4W0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0603700 ^@ http://purl.uniprot.org/uniprot/A0A077Y1B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1035600 ^@ http://purl.uniprot.org/uniprot/A0A077YHS8 ^@ Similarity ^@ Belongs to the DDI1 family. http://togogenome.org/gene/5861:PY17X_1415100 ^@ http://purl.uniprot.org/uniprot/A0A077YBE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1447800 ^@ http://purl.uniprot.org/uniprot/A0A078KCP1 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5861:PY17X_0107600 ^@ http://purl.uniprot.org/uniprot/A0A077XZT1 ^@ Similarity ^@ Belongs to the UbiA prenyltransferase family. http://togogenome.org/gene/5861:PY17X_0919700 ^@ http://purl.uniprot.org/uniprot/A0A077Y4L4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/5861:PY17X_0521700 ^@ http://purl.uniprot.org/uniprot/A0A078K263 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/5861:PY17X_0416100 ^@ http://purl.uniprot.org/uniprot/A0A078K1F8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/5861:PY17X_0941200 ^@ http://purl.uniprot.org/uniprot/A0A077Y5B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DTD family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1307800 ^@ http://purl.uniprot.org/uniprot/A0A077YC68 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0521300 ^@ http://purl.uniprot.org/uniprot/A0A077Y3F4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/5861:PY17X_0913200 ^@ http://purl.uniprot.org/uniprot/A0A078K7C2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/5861:PY17X_0214800 ^@ http://purl.uniprot.org/uniprot/A0A078K5Z3 ^@ Similarity ^@ Belongs to the NMD3 family. http://togogenome.org/gene/5861:PY17X_0606800 ^@ http://purl.uniprot.org/uniprot/A0A077Y256 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NASP family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1326700 ^@ http://purl.uniprot.org/uniprot/A0A078KKN1 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/5861:PY17X_1431600 ^@ http://purl.uniprot.org/uniprot/A0A078KBW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/5861:PY17X_1308200 ^@ http://purl.uniprot.org/uniprot/A0A078KDD7 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/5861:PY17X_0933500 ^@ http://purl.uniprot.org/uniprot/A0A077Y581 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/5861:PY17X_0212900 ^@ http://purl.uniprot.org/uniprot/A0A077XZ30 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/5861:PY17X_1306200 ^@ http://purl.uniprot.org/uniprot/A0A078KDC1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1040400 ^@ http://purl.uniprot.org/uniprot/A0A077YGK0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/5861:PY17X_0417700 ^@ http://purl.uniprot.org/uniprot/A0A077Y0B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/5861:PY17X_0518500 ^@ http://purl.uniprot.org/uniprot/A0A078K898 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/5861:PY17X_1412100 ^@ http://purl.uniprot.org/uniprot/A0A077YBB4 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/5861:PY17X_0607300 ^@ http://purl.uniprot.org/uniprot/A0A077Y260 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1423400 ^@ http://purl.uniprot.org/uniprot/A0A078KBZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AMY1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1116600 ^@ http://purl.uniprot.org/uniprot/A0A077Y7T9 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/5861:PY17X_0316700 ^@ http://purl.uniprot.org/uniprot/A0A078K6F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the activator 1 large subunit family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1236600 ^@ http://purl.uniprot.org/uniprot/A0A077Y7V6 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/5861:PY17X_1365400 ^@ http://purl.uniprot.org/uniprot/A0A077YDP3 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5861:PY17X_0912600 ^@ http://purl.uniprot.org/uniprot/A0A077Y580 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/5861:PY17X_0828000 ^@ http://purl.uniprot.org/uniprot/A0A077Y4K8 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/5861:PY17X_1353900 ^@ http://purl.uniprot.org/uniprot/A0A077Y9N9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/5861:PY17X_1437300 ^@ http://purl.uniprot.org/uniprot/A0A077YB69 ^@ Similarity ^@ Belongs to the phosphatidylethanolamine-binding protein family. http://togogenome.org/gene/5861:PY17X_0935000 ^@ http://purl.uniprot.org/uniprot/A0A077Y599 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. http://togogenome.org/gene/5861:PY17X_1213900 ^@ http://purl.uniprot.org/uniprot/A0A077Y7C1 ^@ Similarity ^@ Belongs to the UQCRB/QCR7 family. http://togogenome.org/gene/5861:PY17X_0315000 ^@ http://purl.uniprot.org/uniprot/A0A077Y0J2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/5861:PY17X_1235600 ^@ http://purl.uniprot.org/uniprot/A0A077Y7U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/5861:PY17X_1364300 ^@ http://purl.uniprot.org/uniprot/A0A077YAB3 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/5861:PY17X_0523200 ^@ http://purl.uniprot.org/uniprot/A0A077Y146 ^@ Similarity ^@ Belongs to the RRF family. http://togogenome.org/gene/5861:PY17X_0704400 ^@ http://purl.uniprot.org/uniprot/A0A4V0KJZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0301700 ^@ http://purl.uniprot.org/uniprot/A0A078K6J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1429400 ^@ http://purl.uniprot.org/uniprot/A0A078KC46 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/5861:PY17X_0406300 ^@ http://purl.uniprot.org/uniprot/A0A078K4E0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/5861:PY17X_0519100 ^@ http://purl.uniprot.org/uniprot/A0A078K7X9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/5861:PY17X_1351600 ^@ http://purl.uniprot.org/uniprot/A0A077YDB9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/5861:PY17X_1016400 ^@ http://purl.uniprot.org/uniprot/A0A4V0KLX6 ^@ Subcellular Location Annotation ^@ COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1108300 ^@ http://purl.uniprot.org/uniprot/A0A077Y7M4 ^@ Similarity ^@ Belongs to the CNOT9 family. http://togogenome.org/gene/5861:PY17X_1231400 ^@ http://purl.uniprot.org/uniprot/A0A078KAL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PWP2 family.|||nucleolus http://togogenome.org/gene/5861:PY17X_0917300 ^@ http://purl.uniprot.org/uniprot/A0A078K7S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/5861:PY17X_1328800 ^@ http://purl.uniprot.org/uniprot/A0A077Y962 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/5861:PY17X_1241000 ^@ http://purl.uniprot.org/uniprot/A0A078KB04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1324700 ^@ http://purl.uniprot.org/uniprot/A0A078KKL2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/5861:PY17X_0941100 ^@ http://purl.uniprot.org/uniprot/A0A077Y7B4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5861:PY17X_1135900 ^@ http://purl.uniprot.org/uniprot/A0A078K9B3 ^@ Similarity ^@ Belongs to the SAS10 family. http://togogenome.org/gene/5861:PY17X_1409200 ^@ http://purl.uniprot.org/uniprot/A0A078KEU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLE1 family.|||nuclear pore complex http://togogenome.org/gene/5861:PY17X_1352400 ^@ http://purl.uniprot.org/uniprot/A0A078KHG4 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/5861:PY17X_1331800 ^@ http://purl.uniprot.org/uniprot/A0A077Y9A5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/5861:PY17X_1219700 ^@ http://purl.uniprot.org/uniprot/A0A077Y7F0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5861:PY17X_0911600 ^@ http://purl.uniprot.org/uniprot/A0A078K7A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/5861:PY17X_1356700 ^@ http://purl.uniprot.org/uniprot/A0A077YBQ0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/5861:PY17X_0311300 ^@ http://purl.uniprot.org/uniprot/A0A078K6S3 ^@ Similarity ^@ Belongs to the RPAP2 family. http://togogenome.org/gene/5861:PY17X_0114100 ^@ http://purl.uniprot.org/uniprot/A0A078K331 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/5861:PY17X_1422400 ^@ http://purl.uniprot.org/uniprot/A0A077YBC6 ^@ Similarity ^@ Belongs to the CFAP91 family. http://togogenome.org/gene/5861:PY17X_0705400 ^@ http://purl.uniprot.org/uniprot/A0A078K8C5 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/5861:PY17X_0829300 ^@ http://purl.uniprot.org/uniprot/A0A078K9M4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RRP8 family.|||Probable methyltransferase required to silence rDNA.|||nucleolus http://togogenome.org/gene/5861:PY17X_0809500 ^@ http://purl.uniprot.org/uniprot/A0A078K659 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1138900 ^@ http://purl.uniprot.org/uniprot/A0A077Y6M0 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/5861:PY17X_0516300 ^@ http://purl.uniprot.org/uniprot/A0A078K4Y7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0822500 ^@ http://purl.uniprot.org/uniprot/A0A078K6F2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. http://togogenome.org/gene/5861:PY17X_0838300 ^@ http://purl.uniprot.org/uniprot/A0A078KAA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/5861:PY17X_1015900 ^@ http://purl.uniprot.org/uniprot/A0A077YFL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histidine acid phosphatase family. VIP1 subfamily.|||cytosol http://togogenome.org/gene/5861:PY17X_1226300 ^@ http://purl.uniprot.org/uniprot/A0A077Y9E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_0412900 ^@ http://purl.uniprot.org/uniprot/A0A078K1C8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/5861:PY17X_1362700 ^@ http://purl.uniprot.org/uniprot/A0A077YBU7 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/5861:PY17X_0304900 ^@ http://purl.uniprot.org/uniprot/Q8WSK0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/5861:PY17X_0407900 ^@ http://purl.uniprot.org/uniprot/A0A077Y1A6 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/5861:PY17X_1304100 ^@ http://purl.uniprot.org/uniprot/A0A077YC36 ^@ Similarity ^@ Belongs to the tubulin family. http://togogenome.org/gene/5861:PY17X_1034700 ^@ http://purl.uniprot.org/uniprot/A0A077YG46 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/5861:PY17X_0814000 ^@ http://purl.uniprot.org/uniprot/A0A078K688 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/5861:PY17X_1115800 ^@ http://purl.uniprot.org/uniprot/A0A077Y9Y0 ^@ Similarity ^@ Belongs to the RRM CWC2 family. http://togogenome.org/gene/5861:PY17X_0912000 ^@ http://purl.uniprot.org/uniprot/A0A078K4D4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1313800 ^@ http://purl.uniprot.org/uniprot/A0A077Y8R6 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/5861:PY17X_1366700 ^@ http://purl.uniprot.org/uniprot/A0A078KLS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/5861:PY17X_1030800 ^@ http://purl.uniprot.org/uniprot/A0A078KFN0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/5861:PY17X_0413300 ^@ http://purl.uniprot.org/uniprot/A0A078K4K5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/5861:PY17X_1131500 ^@ http://purl.uniprot.org/uniprot/A0A077Y6C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB4 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1143800 ^@ http://purl.uniprot.org/uniprot/A0A077Y7Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5861:PY17X_0517400 ^@ http://purl.uniprot.org/uniprot/A0A078K5D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/5861:PY17X_1456800 ^@ http://purl.uniprot.org/uniprot/A0A078KCX9 ^@ Similarity ^@ Belongs to the VPS16 family. http://togogenome.org/gene/5861:PY17X_0810800 ^@ http://purl.uniprot.org/uniprot/A0A4V0KI79 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/5861:PY17X_1417200 ^@ http://purl.uniprot.org/uniprot/A0A077YAI0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0513600 ^@ http://purl.uniprot.org/uniprot/A0A077Y588 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/5861:PY17X_0803600 ^@ http://purl.uniprot.org/uniprot/A0A078K6C1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1419000 ^@ http://purl.uniprot.org/uniprot/A0A078K8S4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_0515100 ^@ http://purl.uniprot.org/uniprot/A0A077Y5A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1429800 ^@ http://purl.uniprot.org/uniprot/A0A077YBJ8 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/5861:PY17X_1231500 ^@ http://purl.uniprot.org/uniprot/Q86SB3 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5861:PY17X_1103100 ^@ http://purl.uniprot.org/uniprot/A0A078K8E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/5861:PY17X_1112500 ^@ http://purl.uniprot.org/uniprot/A0A077Y7Q9 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/5861:PY17X_0621800 ^@ http://purl.uniprot.org/uniprot/A0A078KH35 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/5861:PY17X_1219400 ^@ http://purl.uniprot.org/uniprot/A0A077Y7H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1219600 ^@ http://purl.uniprot.org/uniprot/A0A078KAA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal TPase family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1309100 ^@ http://purl.uniprot.org/uniprot/A0A077YAD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/5861:PY17X_1435600 ^@ http://purl.uniprot.org/uniprot/A0A077YF20 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/5861:PY17X_1039400 ^@ http://purl.uniprot.org/uniprot/A0A077YGJ4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/5861:PY17X_1215800 ^@ http://purl.uniprot.org/uniprot/A0A077Y948 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAP2/GCS1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1215500 ^@ http://purl.uniprot.org/uniprot/A0A078K795 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/5861:PY17X_0512000 ^@ http://purl.uniprot.org/uniprot/A0A077Y0T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/5861:PY17X_0939100 ^@ http://purl.uniprot.org/uniprot/A0A077Y7A5 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/5861:PY17X_0710300 ^@ http://purl.uniprot.org/uniprot/A0A078K8Q3 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/5861:PY17X_1317600 ^@ http://purl.uniprot.org/uniprot/A0A078KKE1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm|||Endoplasmic reticulum|||The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.|||The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. http://togogenome.org/gene/5861:PY17X_1229000 ^@ http://purl.uniprot.org/uniprot/A0A077YBF9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5861:PY17X_1106900 ^@ http://purl.uniprot.org/uniprot/A0A078KBM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1433000 ^@ http://purl.uniprot.org/uniprot/A0A077YEZ8 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5861:PY17X_1360700 ^@ http://purl.uniprot.org/uniprot/A0A078KLL9 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/5861:PY17X_0213700 ^@ http://purl.uniprot.org/uniprot/A0A078K6F0 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5861:PY17X_1353000 ^@ http://purl.uniprot.org/uniprot/A0A077YBM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/5861:PY17X_0915900 ^@ http://purl.uniprot.org/uniprot/A0A078KAZ3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5861:PY17X_1343400 ^@ http://purl.uniprot.org/uniprot/A0A078KEH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_0523000 ^@ http://purl.uniprot.org/uniprot/A0A078K274 ^@ Similarity ^@ Belongs to the endoribonuclease YbeY family. http://togogenome.org/gene/5861:PY17X_1014800 ^@ http://purl.uniprot.org/uniprot/A0A078KC76 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/5861:PY17X_1409800 ^@ http://purl.uniprot.org/uniprot/A0A077YCG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/5861:PY17X_1247000 ^@ http://purl.uniprot.org/uniprot/A0A077Y8E2 ^@ Similarity ^@ Belongs to the TIP family. http://togogenome.org/gene/5861:PY17X_1235900 ^@ http://purl.uniprot.org/uniprot/A0A077YBM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/5861:PY17X_1403200 ^@ http://purl.uniprot.org/uniprot/A0A078KEH2 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal PrmC-related family. http://togogenome.org/gene/5861:PY17X_1135000 ^@ http://purl.uniprot.org/uniprot/A0A077Y8E7 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). http://togogenome.org/gene/5861:PY17X_0416700 ^@ http://purl.uniprot.org/uniprot/A0A077Y096 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/5861:PY17X_0417600 ^@ http://purl.uniprot.org/uniprot/A0A4V0KG76 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/5861:PY17X_1210500 ^@ http://purl.uniprot.org/uniprot/A0A077YB25 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/5861:PY17X_1036300 ^@ http://purl.uniprot.org/uniprot/A0A077YJP9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/5861:PY17X_1441800 ^@ http://purl.uniprot.org/uniprot/A0A077YF84 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5861:PY17X_0812600 ^@ http://purl.uniprot.org/uniprot/A0A078K6I0 ^@ Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. http://togogenome.org/gene/5861:PY17X_1410300 ^@ http://purl.uniprot.org/uniprot/A0A077YCG6 ^@ Similarity ^@ Belongs to the ATPase delta chain family. http://togogenome.org/gene/5861:PY17X_0107100 ^@ http://purl.uniprot.org/uniprot/A0A4V0KG23 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. http://togogenome.org/gene/5861:PY17X_0103400 ^@ http://purl.uniprot.org/uniprot/A0A078JZI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SDE2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_1014700 ^@ http://purl.uniprot.org/uniprot/A0A078KIL0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/5861:PY17X_1461900 ^@ http://purl.uniprot.org/uniprot/A0A078KD38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0103900 ^@ http://purl.uniprot.org/uniprot/A0A077XY56 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/5861:PY17X_0608600 ^@ http://purl.uniprot.org/uniprot/A0A077Y5R0 ^@ Similarity ^@ Belongs to the IPP transferase family. http://togogenome.org/gene/5861:PY17X_0605700 ^@ http://purl.uniprot.org/uniprot/A0A078KDG7 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/5861:PY17X_1247400 ^@ http://purl.uniprot.org/uniprot/A0A077YA76 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5861:PY17X_1426900 ^@ http://purl.uniprot.org/uniprot/A0A078KC21 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5861:PY17X_0823100 ^@ http://purl.uniprot.org/uniprot/A0A077Y3S4 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 3 family. http://togogenome.org/gene/5861:PY17X_1448700 ^@ http://purl.uniprot.org/uniprot/A0A077YC24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1444400 ^@ http://purl.uniprot.org/uniprot/A0A078KC70 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5861:PY17X_1032200 ^@ http://purl.uniprot.org/uniprot/A0A078KCS4 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/5861:PY17X_1324300 ^@ http://purl.uniprot.org/uniprot/A0A078KKA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1448100 ^@ http://purl.uniprot.org/uniprot/A0A077YDI0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/5861:PY17X_1242000 ^@ http://purl.uniprot.org/uniprot/A0A078KB13 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_0519600 ^@ http://purl.uniprot.org/uniprot/A0A077Y2A5 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/5861:PY17X_0304500 ^@ http://purl.uniprot.org/uniprot/A0A078K0J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/5861:PY17X_1121500 ^@ http://purl.uniprot.org/uniprot/A0A078K5W4 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/5861:PY17X_1340800 ^@ http://purl.uniprot.org/uniprot/A0A078KKU7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily. http://togogenome.org/gene/5861:PY17X_1217200 ^@ http://purl.uniprot.org/uniprot/A0A4V0KR08 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/5861:PY17X_1224000 ^@ http://purl.uniprot.org/uniprot/A0A4V0KQF8 ^@ Subcellular Location Annotation ^@ centrosome http://togogenome.org/gene/5861:PY17X_0417400 ^@ http://purl.uniprot.org/uniprot/A0A078K7F6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/5861:PY17X_0212700 ^@ http://purl.uniprot.org/uniprot/A0A078K6D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1350400 ^@ http://purl.uniprot.org/uniprot/A0A078KL20 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5861:PY17X_0712100 ^@ http://purl.uniprot.org/uniprot/A0A078K5J1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5861:PY17X_1003800 ^@ http://purl.uniprot.org/uniprot/A0A077YIL7 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C1 family.|||Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains. http://togogenome.org/gene/5861:PY17X_0911000 ^@ http://purl.uniprot.org/uniprot/A0A078K4A4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0523100 ^@ http://purl.uniprot.org/uniprot/A0A078K532 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_1004000 ^@ http://purl.uniprot.org/uniprot/A0A078KIC2 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5861:PY17X_1304500 ^@ http://purl.uniprot.org/uniprot/A0A078KDB0 ^@ Function|||Subcellular Location Annotation ^@ Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_1111700 ^@ http://purl.uniprot.org/uniprot/A0A078K5K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTP family.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_1335900 ^@ http://purl.uniprot.org/uniprot/A0A077YCU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_1134100 ^@ http://purl.uniprot.org/uniprot/A0A077Y6F8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5861:PY17X_0945700 ^@ http://purl.uniprot.org/uniprot/A0A077Y5E0 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/5861:PY17X_1407300 ^@ http://purl.uniprot.org/uniprot/A0A078KEL3 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5861:PY17X_1338800 ^@ http://purl.uniprot.org/uniprot/A0A078KKS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5861:PY17X_1125900 ^@ http://purl.uniprot.org/uniprot/A0A078KCM2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/5861:PY17X_1323500 ^@ http://purl.uniprot.org/uniprot/A0A078KGG1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0314300 ^@ http://purl.uniprot.org/uniprot/A0A078K6U6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/5861:PY17X_1125300 ^@ http://purl.uniprot.org/uniprot/A0A077Y675 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/5861:PY17X_1430800 ^@ http://purl.uniprot.org/uniprot/A0A077YBK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit A family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/5861:PY17X_0420500 ^@ http://purl.uniprot.org/uniprot/A0A4V0KG74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5861:PY17X_1425600 ^@ http://purl.uniprot.org/uniprot/A0A077YCZ1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/5861:PY17X_1450200 ^@ http://purl.uniprot.org/uniprot/A0A4V0KU58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/5861:PY17X_0834400 ^@ http://purl.uniprot.org/uniprot/A0A077Y7Y3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1309400 ^@ http://purl.uniprot.org/uniprot/A0A077Y995 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/5861:PY17X_1307100 ^@ http://purl.uniprot.org/uniprot/A0A078KJT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Membrane http://togogenome.org/gene/5861:PY17X_0913600 ^@ http://purl.uniprot.org/uniprot/A0A078K4E7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5861:PY17X_0839000 ^@ http://purl.uniprot.org/uniprot/Q26217 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5861:PY17X_0214700 ^@ http://purl.uniprot.org/uniprot/A0A077Y041 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/5861:PY17X_0710800 ^@ http://purl.uniprot.org/uniprot/A0A077Y3G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/5861:PY17X_1230100 ^@ http://purl.uniprot.org/uniprot/A0A077Y9I2 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. http://togogenome.org/gene/5861:PY17X_1022500 ^@ http://purl.uniprot.org/uniprot/A0A077YF31 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5861:PY17X_0818900 ^@ http://purl.uniprot.org/uniprot/A0A078K3A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/5861:PY17X_0719300 ^@ http://purl.uniprot.org/uniprot/A0A077Y352 ^@ Function|||Similarity|||Subunit ^@ Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.|||Homodimer.|||In the C-terminal section; belongs to the thymidylate synthase family.|||In the N-terminal section; belongs to the dihydrofolate reductase family. http://togogenome.org/gene/5861:PY17X_1017200 ^@ http://purl.uniprot.org/uniprot/A0A077YEV0 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/5861:PY17X_1350200 ^@ http://purl.uniprot.org/uniprot/A0A078KHF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5861:PY17X_1332800 ^@ http://purl.uniprot.org/uniprot/A0A078KKK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/5861:PY17X_0616300 ^@ http://purl.uniprot.org/uniprot/A0A077Y1P6 ^@ Similarity ^@ Belongs to the PPC synthetase family. http://togogenome.org/gene/5861:PY17X_0518000 ^@ http://purl.uniprot.org/uniprot/A0A078K892 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family.|||Belongs to the eukaryotic AdoMetDC family. http://togogenome.org/gene/5861:PY17X_1349100 ^@ http://purl.uniprot.org/uniprot/A0A077YAC9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0310100 ^@ http://purl.uniprot.org/uniprot/A0A078K3H6 ^@ Similarity ^@ Belongs to the SRR1 family. http://togogenome.org/gene/5861:PY17X_0302900 ^@ http://purl.uniprot.org/uniprot/A0A077Y0P1 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/5861:PY17X_0208000 ^@ http://purl.uniprot.org/uniprot/A0A078K2V4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5861:PY17X_0403800 ^@ http://purl.uniprot.org/uniprot/A0A078K4B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/5861:PY17X_1138500 ^@ http://purl.uniprot.org/uniprot/A0A078K9K2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/5861:PY17X_1334400 ^@ http://purl.uniprot.org/uniprot/A0A077YCR8 ^@ Similarity ^@ Belongs to the proteasome subunit S1 family. http://togogenome.org/gene/5861:PY17X_0939700 ^@ http://purl.uniprot.org/uniprot/A0A078KB61 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/5861:PY17X_1324800 ^@ http://purl.uniprot.org/uniprot/A0A077Y908 ^@ Similarity ^@ Belongs to the PDCD4 family. http://togogenome.org/gene/5861:PY17X_0935900 ^@ http://purl.uniprot.org/uniprot/A0A078K7X1 ^@ Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/5861:PY17X_1209800 ^@ http://purl.uniprot.org/uniprot/A0A078KDF8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5861:PY17X_0827200 ^@ http://purl.uniprot.org/uniprot/A0A077Y5U5 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/5861:PY17X_1430900 ^@ http://purl.uniprot.org/uniprot/A0A077YEY1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_0315600 ^@ http://purl.uniprot.org/uniprot/A0A077Y1V6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5861:PY17X_0609600 ^@ http://purl.uniprot.org/uniprot/A0A078KAD5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/5861:PY17X_1237600 ^@ http://purl.uniprot.org/uniprot/A0A078KE72 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/5861:PY17X_1368600 ^@ http://purl.uniprot.org/uniprot/A0A078KHU6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5861:PY17X_1460000 ^@ http://purl.uniprot.org/uniprot/A0A077YCP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Nucleus http://togogenome.org/gene/5861:PY17X_1423300 ^@ http://purl.uniprot.org/uniprot/A0A077YEM8 ^@ Cofactor ^@ Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/5861:PY17X_0903000 ^@ http://purl.uniprot.org/uniprot/A0A077Y852 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit beta family. http://togogenome.org/gene/5861:PY17X_0604700 ^@ http://purl.uniprot.org/uniprot/A0A078KDG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/5861:PY17X_1352700 ^@ http://purl.uniprot.org/uniprot/A0A077YDC9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5861:PY17X_0519300 ^@ http://purl.uniprot.org/uniprot/A0A078K508 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/5861:PY17X_0214900 ^@ http://purl.uniprot.org/uniprot/A0A078K0D5 ^@ Similarity ^@ Belongs to the BRX1 family. http://togogenome.org/gene/5861:PY17X_1342900 ^@ http://purl.uniprot.org/uniprot/A0A077YCZ9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/5861:PY17X_0932200 ^@ http://purl.uniprot.org/uniprot/A0A078KAY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1335400 ^@ http://purl.uniprot.org/uniprot/A0A077YCT8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/5861:PY17X_1365300 ^@ http://purl.uniprot.org/uniprot/A0A078KLC0 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5861:PY17X_0522100 ^@ http://purl.uniprot.org/uniprot/A0A078K813 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/5861:PY17X_1216900 ^@ http://purl.uniprot.org/uniprot/A0A078KDI2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/5861:PY17X_0523900 ^@ http://purl.uniprot.org/uniprot/A0A078K830 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/5861:PY17X_1122200 ^@ http://purl.uniprot.org/uniprot/A0A077Y6Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP68 family.|||Cytoplasm|||nucleolus http://togogenome.org/gene/5861:PY17X_1012100 ^@ http://purl.uniprot.org/uniprot/A0A078KIW0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5861:PY17X_0808500 ^@ http://purl.uniprot.org/uniprot/A0A078K6E8 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/5861:PY17X_1439800 ^@ http://purl.uniprot.org/uniprot/A0A077YF64 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5861:PY17X_1231700 ^@ http://purl.uniprot.org/uniprot/A0A077Y7U1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/5861:PY17X_0831800 ^@ http://purl.uniprot.org/uniprot/A0A078K9P9 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5861:PY17X_0721300 ^@ http://purl.uniprot.org/uniprot/A0A078K914 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/5861:PY17X_0620300 ^@ http://purl.uniprot.org/uniprot/A0A077Y1T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF2/ABP1 family.|||nucleolus http://togogenome.org/gene/5861:PY17X_0717200 ^@ http://purl.uniprot.org/uniprot/A0A078K5Z8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5861:PY17X_0819700 ^@ http://purl.uniprot.org/uniprot/A0A077Y5I5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Tetramer of two alpha (regulatory) and two beta (catalytic) chains. http://togogenome.org/gene/5861:PY17X_0515600 ^@ http://purl.uniprot.org/uniprot/A0A077Y263 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/5861:PY17X_1211600 ^@ http://purl.uniprot.org/uniprot/A0A078KA06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/5861:PY17X_0213500 ^@ http://purl.uniprot.org/uniprot/A0A078K326 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/5861:PY17X_0934400 ^@ http://purl.uniprot.org/uniprot/A0A078K7V4 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5861:PY17X_0420300 ^@ http://purl.uniprot.org/uniprot/A0A078K4S2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/5861:PY17X_0619800 ^@ http://purl.uniprot.org/uniprot/A0A077Y1T4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/5861:PY17X_1427100 ^@ http://purl.uniprot.org/uniprot/A0A077YD03 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/5861:PY17X_0213000 ^@ http://purl.uniprot.org/uniprot/A0A077Y3J2 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/5861:PY17X_1449400 ^@ http://purl.uniprot.org/uniprot/A0A077YCD7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/5861:PY17X_1443900 ^@ http://purl.uniprot.org/uniprot/A0A078KC66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/5861:PY17X_1461200 ^@ http://purl.uniprot.org/uniprot/A0A077YBT4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/5861:PY17X_0407000 ^@ http://purl.uniprot.org/uniprot/A0A078K6T2 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/5861:PY17X_0611400 ^@ http://purl.uniprot.org/uniprot/A0A078KH12 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5861:PY17X_0936300 ^@ http://purl.uniprot.org/uniprot/A0A077Y928 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5861:PY17X_0717600 ^@ http://purl.uniprot.org/uniprot/A0A078K5N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/5861:PY17X_1442900 ^@ http://purl.uniprot.org/uniprot/A0A077YC72 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/5861:PY17X_1370100 ^@ http://purl.uniprot.org/uniprot/A0A078KHV7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/5861:PY17X_0809200 ^@ http://purl.uniprot.org/uniprot/A0A078K9I3 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5861:PY17X_0507800 ^@ http://purl.uniprot.org/uniprot/A0A077Y1J3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/5861:PY17X_1240800 ^@ http://purl.uniprot.org/uniprot/A0A078K7U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/5861:PY17X_0902700.1 ^@ http://purl.uniprot.org/uniprot/A0A4V0KKM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/5861:PY17X_0720800 ^@ http://purl.uniprot.org/uniprot/A0A078K907 ^@ Similarity ^@ Belongs to the NOB1 family. http://togogenome.org/gene/5861:PY17X_1330600 ^@ http://purl.uniprot.org/uniprot/A0A077Y8Z6 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/5861:PY17X_1032400 ^@ http://purl.uniprot.org/uniprot/A0A078KFE7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/5861:PY17X_1341600 ^@ http://purl.uniprot.org/uniprot/A0A077Y9C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM10 family.|||Nucleus http://togogenome.org/gene/5861:PY17X_1030100 ^@ http://purl.uniprot.org/uniprot/A0A077YHP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/5861:PY17X_1322100 ^@ http://purl.uniprot.org/uniprot/A0A078KGH2 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/5861:PY17X_1454100 ^@ http://purl.uniprot.org/uniprot/A0A078KG59 ^@ Similarity|||Subunit ^@ Belongs to the ubiquitin-activating E1 family.|||Heterodimer. http://togogenome.org/gene/5861:PY17X_0824200 ^@ http://purl.uniprot.org/uniprot/A0A078K9Y0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/5861:PY17X_1437500 ^@ http://purl.uniprot.org/uniprot/A0A077YBR5 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/5861:PY17X_1016500 ^@ http://purl.uniprot.org/uniprot/A0A078KEY8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/5861:PY17X_1030700 ^@ http://purl.uniprot.org/uniprot/A0A077YG13 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5861:PY17X_1038500 ^@ http://purl.uniprot.org/uniprot/A0A077YFG6 ^@ Similarity ^@ Belongs to the TUB family. http://togogenome.org/gene/5861:PY17X_1008200 ^@ http://purl.uniprot.org/uniprot/A0A077YFB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/5861:PY17X_0617200 ^@ http://purl.uniprot.org/uniprot/A0A077Y423 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit I family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5861:PY17X_0407700 ^@ http://purl.uniprot.org/uniprot/A0A077XZZ7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family.