http://togogenome.org/gene/637390:GCD22_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRX6 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/637390:GCD22_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRL6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/637390:GCD22_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/637390:GCD22_RS15385 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUN4 ^@ PTM|||Similarity ^@ Belongs to the photoactive yellow protein family.|||The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is covalently bound via a thioester linkage. http://togogenome.org/gene/637390:GCD22_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/637390:GCD22_RS14190 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/637390:GCD22_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/637390:GCD22_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A543Q1C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A543Q0J1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVX0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/637390:GCD22_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM35 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/637390:GCD22_RS15960 ^@ http://purl.uniprot.org/uniprot/A0A543Q5N1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/637390:GCD22_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSZ1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS17475 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS14500 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV19 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/637390:GCD22_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A543Q457 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS17780 ^@ http://purl.uniprot.org/uniprot/A0A543Q714 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/637390:GCD22_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNX0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/637390:GCD22_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/637390:GCD22_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM29 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/637390:GCD22_RS16400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/637390:GCD22_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/637390:GCD22_RS16735 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWI3 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/637390:GCD22_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSG8 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/637390:GCD22_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSU0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/637390:GCD22_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSM9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/637390:GCD22_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKV2 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/637390:GCD22_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A543Q0U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/637390:GCD22_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A543Q0T7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS16555 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU63 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/637390:GCD22_RS01240 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM57 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A543Q4Z8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/637390:GCD22_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CheZ family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLS7 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/637390:GCD22_RS13130 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS78 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/637390:GCD22_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A543Q100 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/637390:GCD22_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS16120 ^@ http://purl.uniprot.org/uniprot/A0A543Q5T0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/637390:GCD22_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A543Q5Q6 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/637390:GCD22_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A543Q0H8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS11370 ^@ http://purl.uniprot.org/uniprot/A0A543Q3K5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/637390:GCD22_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/637390:GCD22_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/637390:GCD22_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLQ9 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/637390:GCD22_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM18 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/637390:GCD22_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTR0 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/637390:GCD22_RS15160 ^@ http://purl.uniprot.org/uniprot/A0A543Q545 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/637390:GCD22_RS15075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVC1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/637390:GCD22_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A543Q065 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/637390:GCD22_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A543Q110 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/637390:GCD22_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A543Q7K1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVF8 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/637390:GCD22_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A543Q7N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A543Q0B1 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/637390:GCD22_RS17620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A543Q2K7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/637390:GCD22_RS13115 ^@ http://purl.uniprot.org/uniprot/C5IJZ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/637390:GCD22_RS15165 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS16545 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW30 ^@ Similarity ^@ Belongs to the FrhG family. http://togogenome.org/gene/637390:GCD22_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A543Q0N7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/637390:GCD22_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/637390:GCD22_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A543Q1D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/637390:GCD22_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQI2 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/637390:GCD22_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A543Q1L6 ^@ Caution|||Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP87 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/637390:GCD22_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP99 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/637390:GCD22_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRZ1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/637390:GCD22_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/637390:GCD22_RS13210 ^@ http://purl.uniprot.org/uniprot/A0A543Q3X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/637390:GCD22_RS14385 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV00 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/637390:GCD22_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/637390:GCD22_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN62 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/637390:GCD22_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN49 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/637390:GCD22_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMI3 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/637390:GCD22_RS17250 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVD2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/637390:GCD22_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPA1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/637390:GCD22_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A543Q7X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM40 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/637390:GCD22_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A543Q0B0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/637390:GCD22_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTC9 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/637390:GCD22_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTD1 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/637390:GCD22_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A543Q087 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A543Q0A9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/637390:GCD22_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A543Q3P3 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/637390:GCD22_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM82 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/637390:GCD22_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSC5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN55 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/637390:GCD22_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A543Q7K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/637390:GCD22_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT70 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role. http://togogenome.org/gene/637390:GCD22_RS16085 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/637390:GCD22_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS16490 ^@ http://purl.uniprot.org/uniprot/A0A543Q5U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS14155 ^@ http://purl.uniprot.org/uniprot/A0A543Q4G9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN44 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/637390:GCD22_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/637390:GCD22_RS14855 ^@ http://purl.uniprot.org/uniprot/A0A543Q4X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A543Q4X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/637390:GCD22_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPF4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS15650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTM2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWM8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/637390:GCD22_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLX1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/637390:GCD22_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/637390:GCD22_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A543Q0T4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/637390:GCD22_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/637390:GCD22_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A543Q5E9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/637390:GCD22_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/637390:GCD22_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/637390:GCD22_RS16360 ^@ http://purl.uniprot.org/uniprot/A0A543Q5X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQN6 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/637390:GCD22_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/637390:GCD22_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRK1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS14520 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/637390:GCD22_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV87 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/637390:GCD22_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/637390:GCD22_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVF4 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/637390:GCD22_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR15 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 15 family. http://togogenome.org/gene/637390:GCD22_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A543Q5J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/637390:GCD22_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNK9 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/637390:GCD22_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/637390:GCD22_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU06 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/637390:GCD22_RS16885 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVS2 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/637390:GCD22_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A543Q0S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRG3 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/637390:GCD22_RS14185 ^@ http://purl.uniprot.org/uniprot/A0A543Q4I2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP36 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/637390:GCD22_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A543Q138 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/637390:GCD22_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A543PZ66 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/637390:GCD22_RS17460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/637390:GCD22_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/637390:GCD22_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/637390:GCD22_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/637390:GCD22_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A543Q7Y7 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/637390:GCD22_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRQ0 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/637390:GCD22_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/637390:GCD22_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A543Q2T2 ^@ Caution|||Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/637390:GCD22_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A543Q4L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/637390:GCD22_RS15305 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUY2 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/637390:GCD22_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT79 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRB7 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS14580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU91 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/637390:GCD22_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A543Q0G2 ^@ Caution|||Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR25 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/637390:GCD22_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/637390:GCD22_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A543Q0N3 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/637390:GCD22_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSS0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/637390:GCD22_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNU6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/637390:GCD22_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A543Q3L4 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/637390:GCD22_RS16670 ^@ http://purl.uniprot.org/uniprot/A0A543Q638 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS13110 ^@ http://purl.uniprot.org/uniprot/C5IJZ6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO large chain family. Type I subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterohexadecamer of 8 large chains and 8 small chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/637390:GCD22_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A5P9XME1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/637390:GCD22_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW99 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/637390:GCD22_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/637390:GCD22_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/637390:GCD22_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/637390:GCD22_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/637390:GCD22_RS17495 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUJ3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/637390:GCD22_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/637390:GCD22_RS14570 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/637390:GCD22_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A543Q5J3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/637390:GCD22_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/637390:GCD22_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMN1 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/637390:GCD22_RS16740 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPG1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLR6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNL1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/637390:GCD22_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTL7 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/637390:GCD22_RS16000 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTS1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/637390:GCD22_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A543Q7K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/637390:GCD22_RS17770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/637390:GCD22_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A543PZB8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS14635 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT57 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/637390:GCD22_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNV3 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/637390:GCD22_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNB1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS17255 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVN4 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/637390:GCD22_RS17450 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVA0 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/637390:GCD22_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A543Q0L5 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/637390:GCD22_RS15065 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTD2 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/637390:GCD22_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A543Q2Z8 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU15 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/637390:GCD22_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLV7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS15955 ^@ http://purl.uniprot.org/uniprot/A0A543Q5M9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/637390:GCD22_RS16125 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/637390:GCD22_RS14910 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTZ0 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/637390:GCD22_RS09820 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQI7 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/637390:GCD22_RS15570 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTL2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/637390:GCD22_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNX6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/637390:GCD22_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A543Q7M2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/637390:GCD22_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A543Q0L3 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/637390:GCD22_RS17360 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS15080 ^@ http://purl.uniprot.org/uniprot/A0A543Q517 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/637390:GCD22_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMQ9 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS14245 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU18 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/637390:GCD22_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUD2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS11360 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS09975 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/637390:GCD22_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNI8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/637390:GCD22_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A543Q0D7 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/637390:GCD22_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A543Q3E0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/637390:GCD22_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A543Q1Z9 ^@ Caution|||Similarity ^@ Belongs to the phD/YefM antitoxin family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSE4 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/637390:GCD22_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A543Q377 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/637390:GCD22_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A543Q7B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPB2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/637390:GCD22_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM51 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/637390:GCD22_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A543PYZ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVN3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/637390:GCD22_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRZ4 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A543Q7N2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS17515 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUN2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/637390:GCD22_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A543Q0E8 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTY8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/637390:GCD22_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNJ3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/637390:GCD22_RS14710 ^@ http://purl.uniprot.org/uniprot/A0A543Q4V3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/637390:GCD22_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/637390:GCD22_RS15980 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTQ5 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.|||Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/637390:GCD22_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWF7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/637390:GCD22_RS17070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUF0 ^@ Similarity ^@ Belongs to the MobA/MobL family. http://togogenome.org/gene/637390:GCD22_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A543PZU5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU62 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSI4 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/637390:GCD22_RS15655 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVY9 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/637390:GCD22_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/637390:GCD22_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLX0 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/637390:GCD22_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQF3 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/637390:GCD22_RS17210 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUE3 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/637390:GCD22_RS13480 ^@ http://purl.uniprot.org/uniprot/A0A543Q423 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/637390:GCD22_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRW6 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/637390:GCD22_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/637390:GCD22_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPW2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/637390:GCD22_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A543Q5B3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/637390:GCD22_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTL3 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/637390:GCD22_RS16035 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTR4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/637390:GCD22_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN40 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/637390:GCD22_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN54 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/637390:GCD22_RS16080 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTW1 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/637390:GCD22_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A543Q2K4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/637390:GCD22_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQK1 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/637390:GCD22_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP43 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/637390:GCD22_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.|||The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ). http://togogenome.org/gene/637390:GCD22_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS15340 ^@ http://purl.uniprot.org/uniprot/A0A543Q5C0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/637390:GCD22_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A543Q6T3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/637390:GCD22_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/637390:GCD22_RS15130 ^@ http://purl.uniprot.org/uniprot/A0A543Q531 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/637390:GCD22_RS16805 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM22 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A543Q7N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/637390:GCD22_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/637390:GCD22_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A543Q7B7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/637390:GCD22_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMW0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/637390:GCD22_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A543Q2M3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/637390:GCD22_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A543Q856 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/637390:GCD22_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN03 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/637390:GCD22_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS15420 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTI4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/637390:GCD22_RS15135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUV1 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/637390:GCD22_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSJ5 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN30 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS16570 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV07 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/637390:GCD22_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/637390:GCD22_RS11300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/637390:GCD22_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLF9 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/637390:GCD22_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A5P9XST3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS13920 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTX0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLR0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/637390:GCD22_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A543Q3P5 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/637390:GCD22_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLW7 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/637390:GCD22_RS15835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUX1 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/637390:GCD22_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS10 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. http://togogenome.org/gene/637390:GCD22_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMQ1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/637390:GCD22_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT97 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/637390:GCD22_RS14830 ^@ http://purl.uniprot.org/uniprot/A0A543Q4X9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SoxA family.|||Binds 2 heme groups per subunit.|||Heterodimer of SoxA and SoxX.|||Periplasm http://togogenome.org/gene/637390:GCD22_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A543Q7Q8 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQR3 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/637390:GCD22_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNF2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/637390:GCD22_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNH5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/637390:GCD22_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTZ2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/637390:GCD22_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A543Q762 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS10000 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/637390:GCD22_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNW2 ^@ Function|||Similarity ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. http://togogenome.org/gene/637390:GCD22_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS11490 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/637390:GCD22_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/637390:GCD22_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUQ6 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/637390:GCD22_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/637390:GCD22_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS15465 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A543Q7E8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A5P9XND9 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/637390:GCD22_RS17130 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). http://togogenome.org/gene/637390:GCD22_RS15815 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW20 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/637390:GCD22_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNW4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/637390:GCD22_RS12565 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS43 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A543Q0H5 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A543Q7L6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/637390:GCD22_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKR3 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/637390:GCD22_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A543Q704 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/637390:GCD22_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMQ3 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/637390:GCD22_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM52 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/637390:GCD22_RS15115 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUI9 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/637390:GCD22_RS15485 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTI3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/637390:GCD22_RS17665 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWP4 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/637390:GCD22_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/637390:GCD22_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/637390:GCD22_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMN7 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/637390:GCD22_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/637390:GCD22_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTL5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/637390:GCD22_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A543Q163 ^@ Caution|||Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/637390:GCD22_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A543Q0M4 ^@ Caution|||Similarity ^@ Belongs to the transcriptional regulatory Fis family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS14425 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU47 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/637390:GCD22_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTX7 ^@ Function ^@ Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site. http://togogenome.org/gene/637390:GCD22_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/637390:GCD22_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P0 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/637390:GCD22_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVW8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/637390:GCD22_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR09 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/637390:GCD22_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A543Q0C2 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/637390:GCD22_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A543Q102 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/637390:GCD22_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XML7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/637390:GCD22_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV75 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRV8 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/637390:GCD22_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D7 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/637390:GCD22_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/637390:GCD22_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A543Q6Z7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A543Q532 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/637390:GCD22_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMH0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR42 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL71 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/637390:GCD22_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLK8 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/637390:GCD22_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTI9 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/637390:GCD22_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRW9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS16585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVH0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A543PZC0 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/637390:GCD22_RS17560 ^@ http://purl.uniprot.org/uniprot/A0A543Q6W3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSJ9 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/637390:GCD22_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/637390:GCD22_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLK1 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/637390:GCD22_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKQ2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/637390:GCD22_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A543Q2I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/637390:GCD22_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/637390:GCD22_RS12585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS24 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/637390:GCD22_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSH6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS13505 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLF6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMX9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SoxA family.|||Binds 2 heme groups per subunit.|||Heterodimer of SoxA and SoxX.|||Periplasm http://togogenome.org/gene/637390:GCD22_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TolB family.|||Periplasm http://togogenome.org/gene/637390:GCD22_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16295 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWA9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/637390:GCD22_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A543Q5S1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/637390:GCD22_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPF2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/637390:GCD22_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQG1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/637390:GCD22_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.|||Cell membrane|||Forms a complex with DabA.|||Membrane|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/637390:GCD22_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLL2 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/637390:GCD22_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPH2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/637390:GCD22_RS17840 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVH2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/637390:GCD22_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRH0 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/637390:GCD22_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTE2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLB1 ^@ Similarity ^@ Belongs to the HPrK/P family. http://togogenome.org/gene/637390:GCD22_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A0M4AYB3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/637390:GCD22_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVC3 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/637390:GCD22_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS12345 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS17470 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWV6 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/637390:GCD22_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS12990 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/637390:GCD22_RS13140 ^@ http://purl.uniprot.org/uniprot/A0A543Q3V8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/637390:GCD22_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQR5 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/637390:GCD22_RS13915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTW2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A543Q482 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/637390:GCD22_RS10750 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR68 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A543Q052 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/637390:GCD22_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A543Q7K9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQM5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/637390:GCD22_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/637390:GCD22_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLJ2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A543Q3G7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/637390:GCD22_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A543Q2P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/637390:GCD22_RS09760 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT05 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/637390:GCD22_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLM0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNF5 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/637390:GCD22_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP80 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/637390:GCD22_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVT2 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/637390:GCD22_RS16895 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWK9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OpgD/OpgG family.|||Periplasm http://togogenome.org/gene/637390:GCD22_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A543Q469 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/637390:GCD22_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/637390:GCD22_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A543Q770 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/637390:GCD22_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A543Q6B7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/637390:GCD22_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRX1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/637390:GCD22_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLW1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/637390:GCD22_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVK8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A543Q128 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A543Q106 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/637390:GCD22_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A543Q1J0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPB9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNR3 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/637390:GCD22_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A543Q821 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUZ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/637390:GCD22_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLI1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQP8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/637390:GCD22_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKW5 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/637390:GCD22_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU57 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/637390:GCD22_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/637390:GCD22_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS14135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTM0 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/637390:GCD22_RS17195 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVC4 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/637390:GCD22_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A543Q154 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/637390:GCD22_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNZ5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS16640 ^@ http://purl.uniprot.org/uniprot/A0A543Q646 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/637390:GCD22_RS13425 ^@ http://purl.uniprot.org/uniprot/A0A543Q3Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS13625 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUM3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/637390:GCD22_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMJ5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM33 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/637390:GCD22_RS15970 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/637390:GCD22_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A543Q0G6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT54 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/637390:GCD22_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A543Q144 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/637390:GCD22_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XME3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU80 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRI6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSC0 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/637390:GCD22_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTJ6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/637390:GCD22_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM70 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/637390:GCD22_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLA3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/637390:GCD22_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A543Q7K2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT74 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/637390:GCD22_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMZ1 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/637390:GCD22_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A543Q7M1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X6 ^@ Caution|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPJ4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN23 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/637390:GCD22_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRK0 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS14760 ^@ http://purl.uniprot.org/uniprot/A0A543Q4W0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/637390:GCD22_RS16355 ^@ http://purl.uniprot.org/uniprot/A0A543Q5X6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/637390:GCD22_RS00745 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS13415 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/637390:GCD22_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A543PZ65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/637390:GCD22_RS16455 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/637390:GCD22_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSU4 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/637390:GCD22_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM71 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMK7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/637390:GCD22_RS13660 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSP3 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/637390:GCD22_RS15845 ^@ http://purl.uniprot.org/uniprot/A0A543Q5L6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/637390:GCD22_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/637390:GCD22_RS17775 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUP7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUW0 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/637390:GCD22_RS15665 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUG6 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/637390:GCD22_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/637390:GCD22_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP58 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNS2 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/637390:GCD22_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRU6 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/637390:GCD22_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A543Q1C2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/637390:GCD22_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P8 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/637390:GCD22_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNQ5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/637390:GCD22_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A543PYZ0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ90 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/637390:GCD22_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/637390:GCD22_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSE5 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/637390:GCD22_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQP2 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/637390:GCD22_RS16500 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNY6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/637390:GCD22_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A543Q4X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/637390:GCD22_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPP3 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/637390:GCD22_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A543Q728 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/637390:GCD22_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/637390:GCD22_RS15935 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUL8 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/637390:GCD22_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/637390:GCD22_RS17835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLW0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTN0 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/637390:GCD22_RS14590 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A543Q4M6 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/637390:GCD22_RS13845 ^@ http://purl.uniprot.org/uniprot/A0A543Q4A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Z4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/637390:GCD22_RS17190 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUC5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/637390:GCD22_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A543Q3I7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/637390:GCD22_RS16960 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWM0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/637390:GCD22_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMU1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS16325 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS16830 ^@ http://purl.uniprot.org/uniprot/A0A543Q676 ^@ Caution|||Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPS2 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/637390:GCD22_RS15520 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTK0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/637390:GCD22_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A543Q7E5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/637390:GCD22_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A543Q7C4 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/637390:GCD22_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM86 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/637390:GCD22_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVC6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/637390:GCD22_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A543Q7Q5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/637390:GCD22_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKX4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/637390:GCD22_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A543Q0C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/637390:GCD22_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ27 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/637390:GCD22_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQY7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/637390:GCD22_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A543Q2N4 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/637390:GCD22_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT33 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP37 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 100 family. http://togogenome.org/gene/637390:GCD22_RS16550 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSD8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/637390:GCD22_RS15265 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVS6 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/637390:GCD22_RS06715 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ72 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT18 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS17590 ^@ http://purl.uniprot.org/uniprot/A0A543Q6W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS14495 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTR8 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/637390:GCD22_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A543Q270 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMM1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUH9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A543Q0V6 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/637390:GCD22_RS15645 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV43 ^@ Function|||Similarity ^@ Belongs to the RuBisCO large chain family. Type II subfamily.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. http://togogenome.org/gene/637390:GCD22_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A543Q1E6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/637390:GCD22_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUC6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/637390:GCD22_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMS0 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/637390:GCD22_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM87 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/637390:GCD22_RS15945 ^@ http://purl.uniprot.org/uniprot/A0A543Q5N3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/637390:GCD22_RS17815 ^@ http://purl.uniprot.org/uniprot/A0A543Q706 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/637390:GCD22_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/637390:GCD22_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A543Q7D3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A543Q7P1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A543Q3T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A543Q151 ^@ Cofactor|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits. http://togogenome.org/gene/637390:GCD22_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV37 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/637390:GCD22_RS15490 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/637390:GCD22_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A543Q0L4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/637390:GCD22_RS16920 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMQ0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/637390:GCD22_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQL5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/637390:GCD22_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL48 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A543Q7M8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/637390:GCD22_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNS0 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/637390:GCD22_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN51 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/637390:GCD22_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRS9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/637390:GCD22_RS17485 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVS5 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/637390:GCD22_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKU3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/637390:GCD22_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A543Q101 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/637390:GCD22_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/637390:GCD22_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL89 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ35 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/637390:GCD22_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRG7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/637390:GCD22_RS13075 ^@ http://purl.uniprot.org/uniprot/A0A543Q3W4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/637390:GCD22_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM50 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/637390:GCD22_RS15480 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVW0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/637390:GCD22_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/637390:GCD22_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVT4 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/637390:GCD22_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A543Q0D8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/637390:GCD22_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A543Q1T8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A543PZR1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15275 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/637390:GCD22_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A543Q3S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/637390:GCD22_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMK3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/637390:GCD22_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPC9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/637390:GCD22_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A543Q109 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/637390:GCD22_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A543Q214 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A543Q542 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/637390:GCD22_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A543Q0X1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/637390:GCD22_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A543Q7M0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/637390:GCD22_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNN7 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/637390:GCD22_RS14215 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS14085 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTL0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/637390:GCD22_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/637390:GCD22_RS13860 ^@ http://purl.uniprot.org/uniprot/A0A543Q4A6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/637390:GCD22_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A543Q3V0 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/637390:GCD22_RS17715 ^@ http://purl.uniprot.org/uniprot/A0A543Q707 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM00 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS16095 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUQ1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/637390:GCD22_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A543Q731 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/637390:GCD22_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM61 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/637390:GCD22_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL94 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/637390:GCD22_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/637390:GCD22_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNK2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/637390:GCD22_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT84 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/637390:GCD22_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLM6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A543Q478 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/637390:GCD22_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/637390:GCD22_RS16535 ^@ http://purl.uniprot.org/uniprot/A0A543Q613 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A543Q114 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/637390:GCD22_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A543Q3T2 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/637390:GCD22_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMW3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/637390:GCD22_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVU0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A543Q7R6 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/637390:GCD22_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A543Q2M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/637390:GCD22_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A543Q2L4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/637390:GCD22_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRY0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS11595 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVT3 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/637390:GCD22_RS17160 ^@ http://purl.uniprot.org/uniprot/A0A543Q6A1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/637390:GCD22_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRD0 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/637390:GCD22_RS14645 ^@ http://purl.uniprot.org/uniprot/A0A543Q4T8 ^@ Caution|||Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM62 ^@ Similarity ^@ Belongs to the DNA polymerase HolA subunit family. http://togogenome.org/gene/637390:GCD22_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A543Q158 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN98 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRY7 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/637390:GCD22_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ64 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/637390:GCD22_RS16150 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWY3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/637390:GCD22_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A543Q8F0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQL9 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/637390:GCD22_RS16620 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU27 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/637390:GCD22_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A543Q3U3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/637390:GCD22_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS15610 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/637390:GCD22_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNB9 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/637390:GCD22_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMC9 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/637390:GCD22_RS00590 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16015 ^@ http://purl.uniprot.org/uniprot/A0A543Q5P5 ^@ Caution|||Similarity ^@ Belongs to the band 7/mec-2 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU34 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/637390:GCD22_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTP5 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/637390:GCD22_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A543Q7F0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/637390:GCD22_RS17325 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVV8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/637390:GCD22_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNH2 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/637390:GCD22_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/637390:GCD22_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMP1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/637390:GCD22_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNY8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/637390:GCD22_RS16040 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUP0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/637390:GCD22_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A543Q541 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/637390:GCD22_RS13215 ^@ http://purl.uniprot.org/uniprot/A0A543Q404 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/637390:GCD22_RS05875 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/637390:GCD22_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN19 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/637390:GCD22_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNK7 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/637390:GCD22_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMK5 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/637390:GCD22_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUK9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/637390:GCD22_RS16835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ09 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/637390:GCD22_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A543Q7E6 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTI5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/637390:GCD22_RS17090 ^@ http://purl.uniprot.org/uniprot/A0A543Q685 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A543Q0G1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNP1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/637390:GCD22_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A543Q2A7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A543PZX1 ^@ Caution|||Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A543Q2S6 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/637390:GCD22_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A543Q8A2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSM2 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/637390:GCD22_RS16525 ^@ http://purl.uniprot.org/uniprot/A0A543Q612 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS16440 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU36 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/637390:GCD22_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A543Q034 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW26 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS12940 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A543Q048 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A543Q5H3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A543PYZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/637390:GCD22_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQG8 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/637390:GCD22_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQH8 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/637390:GCD22_RS12075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT59 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/637390:GCD22_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A543Q427 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW77 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/637390:GCD22_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A543Q7F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/637390:GCD22_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPK2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A543Q3S4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNZ1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/637390:GCD22_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A543Q3U7 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/637390:GCD22_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/637390:GCD22_RS00600 ^@ http://purl.uniprot.org/uniprot/A0A543Q078 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/637390:GCD22_RS17045 ^@ http://purl.uniprot.org/uniprot/A0A543Q4Z8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/637390:GCD22_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A543Q4E9 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/637390:GCD22_RS15705 ^@ http://purl.uniprot.org/uniprot/A0A543Q5I5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRQ3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM23 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/637390:GCD22_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM21 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/637390:GCD22_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS11070 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRC6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLU9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/637390:GCD22_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTD6 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/637390:GCD22_RS16140 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW75 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/637390:GCD22_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMN6 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/637390:GCD22_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR93 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNX2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP51 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/637390:GCD22_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL23 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/637390:GCD22_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A543Q105 ^@ Function|||Similarity|||Subunit ^@ Belongs to the high-potential iron-sulfur protein (HiPIP) family.|||Homodimer.|||Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria. http://togogenome.org/gene/637390:GCD22_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A543Q0R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/637390:GCD22_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A543Q097 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A543Q1L6 ^@ Caution|||Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A543Q2B9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/637390:GCD22_RS15505 ^@ http://purl.uniprot.org/uniprot/A0A543Q5E5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/637390:GCD22_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPG8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRG2 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/637390:GCD22_RS11380 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS16 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/637390:GCD22_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP11 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMV0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS16695 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS11405 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS08 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A543PZU0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/637390:GCD22_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTH6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbD subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. http://togogenome.org/gene/637390:GCD22_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSE6 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/637390:GCD22_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL26 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/637390:GCD22_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A543Q0B2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/637390:GCD22_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS89 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/637390:GCD22_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/637390:GCD22_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRM9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/637390:GCD22_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNL0 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/637390:GCD22_RS14380 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/637390:GCD22_RS11210 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR91 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS67 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/637390:GCD22_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRF8 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/637390:GCD22_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSP5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/637390:GCD22_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/637390:GCD22_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQI3 ^@ Function|||Similarity ^@ Belongs to the FliK family.|||Controls the length of the flagellar hook. http://togogenome.org/gene/637390:GCD22_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLD8 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/637390:GCD22_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS17505 ^@ http://purl.uniprot.org/uniprot/A0A5P9XWL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/637390:GCD22_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/637390:GCD22_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL47 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/637390:GCD22_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTB8 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/637390:GCD22_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A543Q1D7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A543Q1Y2 ^@ Caution|||Similarity ^@ Belongs to the type-I restriction system S methylase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/637390:GCD22_RS17530 ^@ http://purl.uniprot.org/uniprot/A0A543Q6W8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV71 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A543Q771 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/637390:GCD22_RS14110 ^@ http://purl.uniprot.org/uniprot/A0A5P9XST4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/637390:GCD22_RS16660 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU83 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS12460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A543Q195 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/637390:GCD22_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A543Q5G8 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/637390:GCD22_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLU8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/637390:GCD22_RS16770 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW72 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A543Q1E2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQZ9 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/637390:GCD22_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A543Q2N3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/637390:GCD22_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTV5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/637390:GCD22_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP48 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/637390:GCD22_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLN6 ^@ Function ^@ Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site. http://togogenome.org/gene/637390:GCD22_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/637390:GCD22_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUY7 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/637390:GCD22_RS16025 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/637390:GCD22_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT20 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/637390:GCD22_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR32 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/637390:GCD22_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/637390:GCD22_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS15700 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/637390:GCD22_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A543Q178 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A543Q0U2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/637390:GCD22_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNN2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/637390:GCD22_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A543Q6D3 ^@ Caution|||Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/637390:GCD22_RS17650 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS59 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/637390:GCD22_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/637390:GCD22_RS10105 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRR0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/637390:GCD22_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A543Q7I3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/637390:GCD22_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM49 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/637390:GCD22_RS12930 ^@ http://purl.uniprot.org/uniprot/A0A5P9XT14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A5P9XL98 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/637390:GCD22_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP50 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/637390:GCD22_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/637390:GCD22_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNP7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/637390:GCD22_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMV3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A543Q261 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A543Q0I3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQ46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/637390:GCD22_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/637390:GCD22_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLX3 ^@ Similarity ^@ Belongs to the complex I 75 kDa subunit family. http://togogenome.org/gene/637390:GCD22_RS17500 ^@ http://purl.uniprot.org/uniprot/A0A543Q6U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/637390:GCD22_RS12180 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSH2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/637390:GCD22_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A543Q7E0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A543Q103 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/637390:GCD22_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNR6 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/637390:GCD22_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A543Q7F8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/637390:GCD22_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A543Q726 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/637390:GCD22_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A543Q7S8 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/637390:GCD22_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A543Q6C1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/637390:GCD22_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW06 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/637390:GCD22_RS17790 ^@ http://purl.uniprot.org/uniprot/A0A5P9XW86 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/637390:GCD22_RS16625 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV17 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/637390:GCD22_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP60 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/637390:GCD22_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/637390:GCD22_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLT6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A5P9XTR7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/637390:GCD22_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A5P9XRH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/637390:GCD22_RS16530 ^@ http://purl.uniprot.org/uniprot/A0A543Q602 ^@ Caution|||Subcellular Location Annotation ^@ Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS17755 ^@ http://purl.uniprot.org/uniprot/A0A543Q6Z6 ^@ Caution|||Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A543Q768 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/637390:GCD22_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A5P9XSC1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A5P9XNC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A5P9XQT8 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/637390:GCD22_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A543Q3V1 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO small chain family.|||Heterohexadecamer of 8 large and 8 small subunits.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS17335 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV85 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A5P9XKV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/637390:GCD22_RS17720 ^@ http://purl.uniprot.org/uniprot/A0A543Q702 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/637390:GCD22_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP21 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/637390:GCD22_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM69 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/637390:GCD22_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A5P9XLQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/637390:GCD22_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XR00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/637390:GCD22_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A543Q7J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/637390:GCD22_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A543Q850 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/637390:GCD22_RS10995 ^@ http://purl.uniprot.org/uniprot/A0A5P9XS35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/637390:GCD22_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A543Q2L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/637390:GCD22_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUY3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/637390:GCD22_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A5P9XN47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/637390:GCD22_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A5P9XM32 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/637390:GCD22_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A5P9XUC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/637390:GCD22_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPB4 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/637390:GCD22_RS16470 ^@ http://purl.uniprot.org/uniprot/A0A5P9XV96 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/637390:GCD22_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A5P9XMP4 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/637390:GCD22_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP67 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A5P9XP46 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/637390:GCD22_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A5P9XVY3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/637390:GCD22_RS16780 ^@ http://purl.uniprot.org/uniprot/A0A5P9XU98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/637390:GCD22_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A5P9XPX6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/637390:GCD22_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A543Q4B7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/637390:GCD22_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A543Q0Y7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family.