http://togogenome.org/gene/649638:TRAD_RS05975 ^@ http://purl.uniprot.org/uniprot/D7CW61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell membrane|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/649638:TRAD_RS11525 ^@ http://purl.uniprot.org/uniprot/D7CSK6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/649638:TRAD_RS00010 ^@ http://purl.uniprot.org/uniprot/D7CWQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/649638:TRAD_RS01610 ^@ http://purl.uniprot.org/uniprot/D7CRG4 ^@ Function ^@ Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/649638:TRAD_RS07735 ^@ http://purl.uniprot.org/uniprot/D7CXS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06810 ^@ http://purl.uniprot.org/uniprot/D7CWY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS14315 ^@ http://purl.uniprot.org/uniprot/D7CVR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS10785 ^@ http://purl.uniprot.org/uniprot/D7CRV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS07830 ^@ http://purl.uniprot.org/uniprot/D7CY61 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/649638:TRAD_RS07750 ^@ http://purl.uniprot.org/uniprot/D7CY45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10425 ^@ http://purl.uniprot.org/uniprot/D7CRC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS05565 ^@ http://purl.uniprot.org/uniprot/D7CVY1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/649638:TRAD_RS10085 ^@ http://purl.uniprot.org/uniprot/D7CR61 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS02220 ^@ http://purl.uniprot.org/uniprot/D7CS43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS04275 ^@ http://purl.uniprot.org/uniprot/D7CU95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS05130 ^@ http://purl.uniprot.org/uniprot/D7CVC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/649638:TRAD_RS10195 ^@ http://purl.uniprot.org/uniprot/D7CR83 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/649638:TRAD_RS03730 ^@ http://purl.uniprot.org/uniprot/D7CTM6 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS09050 ^@ http://purl.uniprot.org/uniprot/D7CQG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS09575 ^@ http://purl.uniprot.org/uniprot/D7CQR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13730 ^@ http://purl.uniprot.org/uniprot/D7CV28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/649638:TRAD_RS03295 ^@ http://purl.uniprot.org/uniprot/D7CTD6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/649638:TRAD_RS01130 ^@ http://purl.uniprot.org/uniprot/D7CY02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS04990 ^@ http://purl.uniprot.org/uniprot/D7CVA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13105 ^@ http://purl.uniprot.org/uniprot/D7CUE9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/649638:TRAD_RS12330 ^@ http://purl.uniprot.org/uniprot/D7CTN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/649638:TRAD_RS07285 ^@ http://purl.uniprot.org/uniprot/D7CXJ0 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/649638:TRAD_RS09950 ^@ http://purl.uniprot.org/uniprot/D7CQY9 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/649638:TRAD_RS07960 ^@ http://purl.uniprot.org/uniprot/D7CY87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS01020 ^@ http://purl.uniprot.org/uniprot/D7CXY0 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/649638:TRAD_RS14225 ^@ http://purl.uniprot.org/uniprot/D7CVP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS12720 ^@ http://purl.uniprot.org/uniprot/D7CTW0 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/649638:TRAD_RS04560 ^@ http://purl.uniprot.org/uniprot/D7CUQ3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/649638:TRAD_RS00720 ^@ http://purl.uniprot.org/uniprot/D7CXF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/649638:TRAD_RS13865 ^@ http://purl.uniprot.org/uniprot/D7CV54 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/649638:TRAD_RS15075 ^@ http://purl.uniprot.org/uniprot/D7CUL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13355 ^@ http://purl.uniprot.org/uniprot/D7CUJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS14780 ^@ http://purl.uniprot.org/uniprot/D7CWB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS05550 ^@ http://purl.uniprot.org/uniprot/D7CVX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/649638:TRAD_RS05460 ^@ http://purl.uniprot.org/uniprot/D7CVJ6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS06915 ^@ http://purl.uniprot.org/uniprot/D7CX07 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS02455 ^@ http://purl.uniprot.org/uniprot/D7CS90 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS03050 ^@ http://purl.uniprot.org/uniprot/D7CSX3 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/649638:TRAD_RS05135 ^@ http://purl.uniprot.org/uniprot/D7CVC8 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/649638:TRAD_RS15090 ^@ http://purl.uniprot.org/uniprot/D7CUR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02555 ^@ http://purl.uniprot.org/uniprot/D7CSB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01400 ^@ http://purl.uniprot.org/uniprot/D7CR13 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/649638:TRAD_RS07655 ^@ http://purl.uniprot.org/uniprot/D7CXR3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/649638:TRAD_RS01435 ^@ http://purl.uniprot.org/uniprot/D7CR20 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/649638:TRAD_RS12785 ^@ http://purl.uniprot.org/uniprot/D7CTX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS01170 ^@ http://purl.uniprot.org/uniprot/D7CY10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13930 ^@ http://purl.uniprot.org/uniprot/D7CV67 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/649638:TRAD_RS02165 ^@ http://purl.uniprot.org/uniprot/D7CS33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/649638:TRAD_RS03045 ^@ http://purl.uniprot.org/uniprot/D7CSX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08345 ^@ http://purl.uniprot.org/uniprot/D7CQ18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06685 ^@ http://purl.uniprot.org/uniprot/D7CWV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/649638:TRAD_RS06355 ^@ http://purl.uniprot.org/uniprot/D7CWK2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/649638:TRAD_RS03795 ^@ http://purl.uniprot.org/uniprot/D7CTZ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/649638:TRAD_RS11820 ^@ http://purl.uniprot.org/uniprot/D7CT19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/649638:TRAD_RS08435 ^@ http://purl.uniprot.org/uniprot/D7CQ36 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/649638:TRAD_RS14835 ^@ http://purl.uniprot.org/uniprot/D7CWC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS06275 ^@ http://purl.uniprot.org/uniprot/D7CWI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS13510 ^@ http://purl.uniprot.org/uniprot/D7CUY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS09780 ^@ http://purl.uniprot.org/uniprot/D7CQV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00075 ^@ http://purl.uniprot.org/uniprot/D7CWR7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS14435 ^@ http://purl.uniprot.org/uniprot/D7CVT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06905 ^@ http://purl.uniprot.org/uniprot/D7CX04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/649638:TRAD_RS10690 ^@ http://purl.uniprot.org/uniprot/D7CRT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/649638:TRAD_RS09495 ^@ http://purl.uniprot.org/uniprot/D7CQP9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/649638:TRAD_RS02420 ^@ http://purl.uniprot.org/uniprot/D7CS83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06165 ^@ http://purl.uniprot.org/uniprot/D7CWG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS14805 ^@ http://purl.uniprot.org/uniprot/D7CWC3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS10065 ^@ http://purl.uniprot.org/uniprot/D7CR57 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/649638:TRAD_RS07190 ^@ http://purl.uniprot.org/uniprot/D7CXH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS01115 ^@ http://purl.uniprot.org/uniprot/D7CXZ9 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/649638:TRAD_RS06940 ^@ http://purl.uniprot.org/uniprot/D7CX12 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS13150 ^@ http://purl.uniprot.org/uniprot/D7CUF9 ^@ Similarity ^@ Belongs to the 2-oxoadipate dioxygenase/decarboxylase family. http://togogenome.org/gene/649638:TRAD_RS14215 ^@ http://purl.uniprot.org/uniprot/D7CVP4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS00185 ^@ http://purl.uniprot.org/uniprot/D7CWT8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS07880 ^@ http://purl.uniprot.org/uniprot/D7CY71 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/649638:TRAD_RS14540 ^@ http://purl.uniprot.org/uniprot/D7CVW2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/649638:TRAD_RS00645 ^@ http://purl.uniprot.org/uniprot/D7CXE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS13935 ^@ http://purl.uniprot.org/uniprot/D7CV68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS07045 ^@ http://purl.uniprot.org/uniprot/D7CX34 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family.|||Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/649638:TRAD_RS12210 ^@ http://purl.uniprot.org/uniprot/D7CT99 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/649638:TRAD_RS05640 ^@ http://purl.uniprot.org/uniprot/D7CVZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS12460 ^@ http://purl.uniprot.org/uniprot/D7CTR0 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/649638:TRAD_RS02295 ^@ http://purl.uniprot.org/uniprot/D7CS58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS03285 ^@ http://purl.uniprot.org/uniprot/D7CTD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS04765 ^@ http://purl.uniprot.org/uniprot/D7CUU4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/649638:TRAD_RS11335 ^@ http://purl.uniprot.org/uniprot/D7CSG9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/649638:TRAD_RS12285 ^@ http://purl.uniprot.org/uniprot/D7CTB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS07165 ^@ http://purl.uniprot.org/uniprot/D7CX60 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS10010 ^@ http://purl.uniprot.org/uniprot/D7CR00 ^@ Function|||Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/649638:TRAD_RS02430 ^@ http://purl.uniprot.org/uniprot/D7CS85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/649638:TRAD_RS05755 ^@ http://purl.uniprot.org/uniprot/D7CW19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06135 ^@ http://purl.uniprot.org/uniprot/D7CWF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10950 ^@ http://purl.uniprot.org/uniprot/D7CRY8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/649638:TRAD_RS06325 ^@ http://purl.uniprot.org/uniprot/D7CWJ6 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/649638:TRAD_RS06390 ^@ http://purl.uniprot.org/uniprot/D7CWK9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/649638:TRAD_RS08675 ^@ http://purl.uniprot.org/uniprot/D7CQ84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS03425 ^@ http://purl.uniprot.org/uniprot/D7CTG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS14100 ^@ http://purl.uniprot.org/uniprot/D7CVL8 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS02920 ^@ http://purl.uniprot.org/uniprot/D7CSU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS14460 ^@ http://purl.uniprot.org/uniprot/D7CVU4 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/649638:TRAD_RS00910 ^@ http://purl.uniprot.org/uniprot/D7CXV8 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS11540 ^@ http://purl.uniprot.org/uniprot/D7CSK9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS05425 ^@ http://purl.uniprot.org/uniprot/D7CVI7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/649638:TRAD_RS00690 ^@ http://purl.uniprot.org/uniprot/D7CXF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS04995 ^@ http://purl.uniprot.org/uniprot/D7CVA1 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/649638:TRAD_RS09580 ^@ http://purl.uniprot.org/uniprot/D7CQR5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS05305 ^@ http://purl.uniprot.org/uniprot/D7CVG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/649638:TRAD_RS02315 ^@ http://purl.uniprot.org/uniprot/D7CS62 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01870 ^@ http://purl.uniprot.org/uniprot/D7CRL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/649638:TRAD_RS07625 ^@ http://purl.uniprot.org/uniprot/D7CXQ7 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/649638:TRAD_RS10150 ^@ http://purl.uniprot.org/uniprot/D7CR74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01465 ^@ http://purl.uniprot.org/uniprot/D7CR26 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/649638:TRAD_RS12290 ^@ http://purl.uniprot.org/uniprot/D7CTB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/649638:TRAD_RS05225 ^@ http://purl.uniprot.org/uniprot/D7CVE6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS12725 ^@ http://purl.uniprot.org/uniprot/D7CTW1 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS11740 ^@ http://purl.uniprot.org/uniprot/D7CSP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07360 ^@ http://purl.uniprot.org/uniprot/D7CXK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Membrane|||Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/649638:TRAD_RS00865 ^@ http://purl.uniprot.org/uniprot/D7CXV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/649638:TRAD_RS10400 ^@ http://purl.uniprot.org/uniprot/D7CRC2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/649638:TRAD_RS10565 ^@ http://purl.uniprot.org/uniprot/D7CRF1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/649638:TRAD_RS15065 ^@ http://purl.uniprot.org/uniprot/D7CU73 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS01055 ^@ http://purl.uniprot.org/uniprot/D7CXY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS12260 ^@ http://purl.uniprot.org/uniprot/D7CTA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/649638:TRAD_RS10020 ^@ http://purl.uniprot.org/uniprot/D7CR02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS09900 ^@ http://purl.uniprot.org/uniprot/D7CQX9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/649638:TRAD_RS05220 ^@ http://purl.uniprot.org/uniprot/D7CVE5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/649638:TRAD_RS13265 ^@ http://purl.uniprot.org/uniprot/D7CUI0 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/649638:TRAD_RS11785 ^@ http://purl.uniprot.org/uniprot/D7CT12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Cyclase 1 superfamily. KynB family.|||Binds 2 zinc ions per subunit.|||Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS09460 ^@ http://purl.uniprot.org/uniprot/D7CQP2 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/649638:TRAD_RS10380 ^@ http://purl.uniprot.org/uniprot/D7CRB8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/649638:TRAD_RS07965 ^@ http://purl.uniprot.org/uniprot/D7CY88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS12455 ^@ http://purl.uniprot.org/uniprot/D7CTQ9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/649638:TRAD_RS10755 ^@ http://purl.uniprot.org/uniprot/D7CRV0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/649638:TRAD_RS04585 ^@ http://purl.uniprot.org/uniprot/D7CUQ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS12150 ^@ http://purl.uniprot.org/uniprot/D7CT86 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/649638:TRAD_RS05730 ^@ http://purl.uniprot.org/uniprot/D7CW14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/649638:TRAD_RS14320 ^@ http://purl.uniprot.org/uniprot/D7CVR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS06925 ^@ http://purl.uniprot.org/uniprot/D7CX09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01635 ^@ http://purl.uniprot.org/uniprot/D7CRG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS08595 ^@ http://purl.uniprot.org/uniprot/D7CQ68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS13430 ^@ http://purl.uniprot.org/uniprot/D7CUL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS05415 ^@ http://purl.uniprot.org/uniprot/D7CVI5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS08340 ^@ http://purl.uniprot.org/uniprot/D7CQ17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01205 ^@ http://purl.uniprot.org/uniprot/D7CY17 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/649638:TRAD_RS02445 ^@ http://purl.uniprot.org/uniprot/D7CS88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS07980 ^@ http://purl.uniprot.org/uniprot/D7CY91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/649638:TRAD_RS11530 ^@ http://purl.uniprot.org/uniprot/D7CSK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00055 ^@ http://purl.uniprot.org/uniprot/D7CWR3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/649638:TRAD_RS11790 ^@ http://purl.uniprot.org/uniprot/D7CT13 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/649638:TRAD_RS06950 ^@ http://purl.uniprot.org/uniprot/D7CX14 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/649638:TRAD_RS11985 ^@ http://purl.uniprot.org/uniprot/D7CT52 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/649638:TRAD_RS08575 ^@ http://purl.uniprot.org/uniprot/D7CQ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS12900 ^@ http://purl.uniprot.org/uniprot/D7CUA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS05585 ^@ http://purl.uniprot.org/uniprot/D7CVY6 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/649638:TRAD_RS10095 ^@ http://purl.uniprot.org/uniprot/D7CR63 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/649638:TRAD_RS01585 ^@ http://purl.uniprot.org/uniprot/D7CR49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06865 ^@ http://purl.uniprot.org/uniprot/D7CWZ6 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/649638:TRAD_RS09390 ^@ http://purl.uniprot.org/uniprot/D7CQM7 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/649638:TRAD_RS12555 ^@ http://purl.uniprot.org/uniprot/D7CTS7 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/649638:TRAD_RS05300 ^@ http://purl.uniprot.org/uniprot/D7CVG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/649638:TRAD_RS11745 ^@ http://purl.uniprot.org/uniprot/D7CSP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13135 ^@ http://purl.uniprot.org/uniprot/D7CUF6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/649638:TRAD_RS00560 ^@ http://purl.uniprot.org/uniprot/D7CXC5 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family. http://togogenome.org/gene/649638:TRAD_RS02425 ^@ http://purl.uniprot.org/uniprot/D7CS84 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/649638:TRAD_RS06595 ^@ http://purl.uniprot.org/uniprot/D7CWQ0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS02285 ^@ http://purl.uniprot.org/uniprot/D7CS56 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/649638:TRAD_RS06590 ^@ http://purl.uniprot.org/uniprot/D7CWP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/649638:TRAD_RS00345 ^@ http://purl.uniprot.org/uniprot/D7CX88 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/649638:TRAD_RS03750 ^@ http://purl.uniprot.org/uniprot/D7CTN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11340 ^@ http://purl.uniprot.org/uniprot/D7CSH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS04185 ^@ http://purl.uniprot.org/uniprot/D7CU77 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/649638:TRAD_RS00880 ^@ http://purl.uniprot.org/uniprot/D7CXV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal/bacterial/fungal opsin family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS14055 ^@ http://purl.uniprot.org/uniprot/D7CVK9 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS01850 ^@ http://purl.uniprot.org/uniprot/D7CRL3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/649638:TRAD_RS13620 ^@ http://purl.uniprot.org/uniprot/D7CV06 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/649638:TRAD_RS03105 ^@ http://purl.uniprot.org/uniprot/D7CSY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS01065 ^@ http://purl.uniprot.org/uniprot/D7CXY9 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/649638:TRAD_RS04875 ^@ http://purl.uniprot.org/uniprot/D7CUW4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/649638:TRAD_RS01715 ^@ http://purl.uniprot.org/uniprot/D7CRI5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/649638:TRAD_RS00220 ^@ http://purl.uniprot.org/uniprot/D7CX62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07155 ^@ http://purl.uniprot.org/uniprot/D7CX58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS12355 ^@ http://purl.uniprot.org/uniprot/D7CTP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/649638:TRAD_RS06730 ^@ http://purl.uniprot.org/uniprot/D7CWW8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS15035 ^@ http://purl.uniprot.org/uniprot/D7CTG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/649638:TRAD_RS10355 ^@ http://purl.uniprot.org/uniprot/D7CRB4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/649638:TRAD_RS11535 ^@ http://purl.uniprot.org/uniprot/D7CSK8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS05270 ^@ http://purl.uniprot.org/uniprot/D7CVF5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS05200 ^@ http://purl.uniprot.org/uniprot/D7CVE1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/649638:TRAD_RS00890 ^@ http://purl.uniprot.org/uniprot/D7CXV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/649638:TRAD_RS00500 ^@ http://purl.uniprot.org/uniprot/D7CXB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/649638:TRAD_RS11665 ^@ http://purl.uniprot.org/uniprot/D7CSN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS14720 ^@ http://purl.uniprot.org/uniprot/D7CWA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10100 ^@ http://purl.uniprot.org/uniprot/D7CR64 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 53 family. http://togogenome.org/gene/649638:TRAD_RS02040 ^@ http://purl.uniprot.org/uniprot/D7CRQ1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS11715 ^@ http://purl.uniprot.org/uniprot/D7CSP2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/649638:TRAD_RS07940 ^@ http://purl.uniprot.org/uniprot/D7CY83 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/649638:TRAD_RS11625 ^@ http://purl.uniprot.org/uniprot/D7CSM6 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/649638:TRAD_RS08015 ^@ http://purl.uniprot.org/uniprot/D7CY98 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/649638:TRAD_RS01295 ^@ http://purl.uniprot.org/uniprot/D7CY32 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS13795 ^@ http://purl.uniprot.org/uniprot/D7CV41 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS04110 ^@ http://purl.uniprot.org/uniprot/D7CU62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06820 ^@ http://purl.uniprot.org/uniprot/D7CWY7 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/649638:TRAD_RS10670 ^@ http://purl.uniprot.org/uniprot/D7CRT3 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/649638:TRAD_RS11565 ^@ http://purl.uniprot.org/uniprot/D7CSL4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS05610 ^@ http://purl.uniprot.org/uniprot/D7CVZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS11930 ^@ http://purl.uniprot.org/uniprot/D7CT41 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/649638:TRAD_RS07160 ^@ http://purl.uniprot.org/uniprot/D7CX59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS03635 ^@ http://purl.uniprot.org/uniprot/D7CTK7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS12765 ^@ http://purl.uniprot.org/uniprot/D7CTW9 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/649638:TRAD_RS07800 ^@ http://purl.uniprot.org/uniprot/D7CY55 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/649638:TRAD_RS01830 ^@ http://purl.uniprot.org/uniprot/D7CRK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/649638:TRAD_RS05470 ^@ http://purl.uniprot.org/uniprot/D7CVJ8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/649638:TRAD_RS03325 ^@ http://purl.uniprot.org/uniprot/D7CTE2 ^@ Function|||Similarity ^@ Belongs to the UxaE family.|||Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA). http://togogenome.org/gene/649638:TRAD_RS10420 ^@ http://purl.uniprot.org/uniprot/D7CRC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS06910 ^@ http://purl.uniprot.org/uniprot/D7CX06 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/649638:TRAD_RS13895 ^@ http://purl.uniprot.org/uniprot/D7CV60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS15325 ^@ http://purl.uniprot.org/uniprot/D7CRB5 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/649638:TRAD_RS01095 ^@ http://purl.uniprot.org/uniprot/D7CXZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS08540 ^@ http://purl.uniprot.org/uniprot/D7CQ57 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS05255 ^@ http://purl.uniprot.org/uniprot/D7CVF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/649638:TRAD_RS09720 ^@ http://purl.uniprot.org/uniprot/D7CQU3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS05815 ^@ http://purl.uniprot.org/uniprot/D7CW32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10550 ^@ http://purl.uniprot.org/uniprot/D7CRE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS04295 ^@ http://purl.uniprot.org/uniprot/D7CU99 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/649638:TRAD_RS08615 ^@ http://purl.uniprot.org/uniprot/D7CQ72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS11375 ^@ http://purl.uniprot.org/uniprot/D7CSH6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/649638:TRAD_RS12550 ^@ http://purl.uniprot.org/uniprot/D7CTS6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/649638:TRAD_RS05160 ^@ http://purl.uniprot.org/uniprot/D7CVD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/649638:TRAD_RS12335 ^@ http://purl.uniprot.org/uniprot/D7CTN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/649638:TRAD_RS10520 ^@ http://purl.uniprot.org/uniprot/D7CRE3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/649638:TRAD_RS04825 ^@ http://purl.uniprot.org/uniprot/D7CUV4 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/649638:TRAD_RS05090 ^@ http://purl.uniprot.org/uniprot/D7CVB9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/649638:TRAD_RS05385 ^@ http://purl.uniprot.org/uniprot/D7CVH9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/649638:TRAD_RS14710 ^@ http://purl.uniprot.org/uniprot/D7CWA4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS14105 ^@ http://purl.uniprot.org/uniprot/D7CVL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AlgJ family.|||Cell inner membrane|||Periplasm http://togogenome.org/gene/649638:TRAD_RS09305 ^@ http://purl.uniprot.org/uniprot/D7CQL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS04785 ^@ http://purl.uniprot.org/uniprot/D7CUU9 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS02825 ^@ http://purl.uniprot.org/uniprot/D7CST1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS07145 ^@ http://purl.uniprot.org/uniprot/D7CX56 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/649638:TRAD_RS08520 ^@ http://purl.uniprot.org/uniprot/D7CQ53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14865 ^@ http://purl.uniprot.org/uniprot/D7CWD5 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/649638:TRAD_RS04985 ^@ http://purl.uniprot.org/uniprot/D7CV99 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/649638:TRAD_RS14820 ^@ http://purl.uniprot.org/uniprot/D7CWC6 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/649638:TRAD_RS06440 ^@ http://purl.uniprot.org/uniprot/D7CWL9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/649638:TRAD_RS10680 ^@ http://purl.uniprot.org/uniprot/D7CRT5 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/649638:TRAD_RS03040 ^@ http://purl.uniprot.org/uniprot/D7CSX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07290 ^@ http://purl.uniprot.org/uniprot/D7CXJ1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/649638:TRAD_RS09810 ^@ http://purl.uniprot.org/uniprot/D7CQW1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/649638:TRAD_RS05030 ^@ http://purl.uniprot.org/uniprot/D7CVA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10965 ^@ http://purl.uniprot.org/uniprot/D7CRZ1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS04120 ^@ http://purl.uniprot.org/uniprot/D7CU64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS02725 ^@ http://purl.uniprot.org/uniprot/D7CSR0 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/649638:TRAD_RS11110 ^@ http://purl.uniprot.org/uniprot/D7CS17 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/649638:TRAD_RS05870 ^@ http://purl.uniprot.org/uniprot/D7CW43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS12325 ^@ http://purl.uniprot.org/uniprot/D7CTN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/649638:TRAD_RS09350 ^@ http://purl.uniprot.org/uniprot/D7CQL9 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/649638:TRAD_RS07955 ^@ http://purl.uniprot.org/uniprot/D7CY86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01215 ^@ http://purl.uniprot.org/uniprot/D7CY19 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS06080 ^@ http://purl.uniprot.org/uniprot/D7CWE7 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/649638:TRAD_RS02975 ^@ http://purl.uniprot.org/uniprot/D7CSW0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01785 ^@ http://purl.uniprot.org/uniprot/D7CRJ9 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/649638:TRAD_RS13940 ^@ http://purl.uniprot.org/uniprot/D7CV69 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS05045 ^@ http://purl.uniprot.org/uniprot/D7CVB0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/649638:TRAD_RS09850 ^@ http://purl.uniprot.org/uniprot/D7CQW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01965 ^@ http://purl.uniprot.org/uniprot/D7CRN6 ^@ Similarity ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily. http://togogenome.org/gene/649638:TRAD_RS06825 ^@ http://purl.uniprot.org/uniprot/D7CWY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/649638:TRAD_RS04505 ^@ http://purl.uniprot.org/uniprot/D7CUP2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/649638:TRAD_RS05855 ^@ http://purl.uniprot.org/uniprot/D7CW40 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/649638:TRAD_RS10810 ^@ http://purl.uniprot.org/uniprot/D7CRW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/649638:TRAD_RS04860 ^@ http://purl.uniprot.org/uniprot/D7CUW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS03190 ^@ http://purl.uniprot.org/uniprot/D7CSR8 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/649638:TRAD_RS08120 ^@ http://purl.uniprot.org/uniprot/D7CYB8 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS09365 ^@ http://purl.uniprot.org/uniprot/D7CQM2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS03700 ^@ http://purl.uniprot.org/uniprot/D7CTM1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/649638:TRAD_RS04600 ^@ http://purl.uniprot.org/uniprot/D7CUR2 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS02815 ^@ http://purl.uniprot.org/uniprot/D7CSS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/649638:TRAD_RS00985 ^@ http://purl.uniprot.org/uniprot/D7CXX3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/649638:TRAD_RS06055 ^@ http://purl.uniprot.org/uniprot/D7CWE1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/649638:TRAD_RS08660 ^@ http://purl.uniprot.org/uniprot/D7CQ81 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS09985 ^@ http://purl.uniprot.org/uniprot/D7CQZ5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/649638:TRAD_RS07230 ^@ http://purl.uniprot.org/uniprot/D7CXH9 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/649638:TRAD_RS02065 ^@ http://purl.uniprot.org/uniprot/D7CRQ6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/649638:TRAD_RS00975 ^@ http://purl.uniprot.org/uniprot/D7CXX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13580 ^@ http://purl.uniprot.org/uniprot/D7CUZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS05265 ^@ http://purl.uniprot.org/uniprot/D7CVF4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/649638:TRAD_RS01410 ^@ http://purl.uniprot.org/uniprot/D7CR15 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/649638:TRAD_RS05165 ^@ http://purl.uniprot.org/uniprot/D7CVD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS07455 ^@ http://purl.uniprot.org/uniprot/D7CXM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS10450 ^@ http://purl.uniprot.org/uniprot/D7CRD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/649638:TRAD_RS03890 ^@ http://purl.uniprot.org/uniprot/D7CU18 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/649638:TRAD_RS07690 ^@ http://purl.uniprot.org/uniprot/D7CXS0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/649638:TRAD_RS11885 ^@ http://purl.uniprot.org/uniprot/D7CT32 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/649638:TRAD_RS12775 ^@ http://purl.uniprot.org/uniprot/D7CTX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS12400 ^@ http://purl.uniprot.org/uniprot/D7CTP8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS08645 ^@ http://purl.uniprot.org/uniprot/D7CQ78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS11430 ^@ http://purl.uniprot.org/uniprot/D7CSI7 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/649638:TRAD_RS03765 ^@ http://purl.uniprot.org/uniprot/D7CTN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS09585 ^@ http://purl.uniprot.org/uniprot/D7CQR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/649638:TRAD_RS05670 ^@ http://purl.uniprot.org/uniprot/D7CW02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.|||Periplasm|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/649638:TRAD_RS04405 ^@ http://purl.uniprot.org/uniprot/D7CUM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/649638:TRAD_RS14480 ^@ http://purl.uniprot.org/uniprot/D7CVU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS10250 ^@ http://purl.uniprot.org/uniprot/D7CR93 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/649638:TRAD_RS11705 ^@ http://purl.uniprot.org/uniprot/D7CSP1 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/649638:TRAD_RS10285 ^@ http://purl.uniprot.org/uniprot/D7CRA0 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/649638:TRAD_RS02525 ^@ http://purl.uniprot.org/uniprot/D7CSA5 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/649638:TRAD_RS08525 ^@ http://purl.uniprot.org/uniprot/D7CQ54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14305 ^@ http://purl.uniprot.org/uniprot/D7CVR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06860 ^@ http://purl.uniprot.org/uniprot/D7CWZ5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/649638:TRAD_RS14810 ^@ http://purl.uniprot.org/uniprot/D7CWC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/649638:TRAD_RS01795 ^@ http://purl.uniprot.org/uniprot/D7CRK1 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/649638:TRAD_RS14675 ^@ http://purl.uniprot.org/uniprot/D7CW97 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/649638:TRAD_RS09425 ^@ http://purl.uniprot.org/uniprot/D7CQN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/649638:TRAD_RS04975 ^@ http://purl.uniprot.org/uniprot/D7CV97 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/649638:TRAD_RS02925 ^@ http://purl.uniprot.org/uniprot/D7CSV0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/649638:TRAD_RS12190 ^@ http://purl.uniprot.org/uniprot/D7CT95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/649638:TRAD_RS12100 ^@ http://purl.uniprot.org/uniprot/D7CT76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01000 ^@ http://purl.uniprot.org/uniprot/D7CXX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS14700 ^@ http://purl.uniprot.org/uniprot/D7CWA2 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/649638:TRAD_RS05720 ^@ http://purl.uniprot.org/uniprot/D7CW12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS07425 ^@ http://purl.uniprot.org/uniprot/D7CXL7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS00465 ^@ http://purl.uniprot.org/uniprot/D7CXA7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/649638:TRAD_RS09775 ^@ http://purl.uniprot.org/uniprot/D7CQV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/649638:TRAD_RS00455 ^@ http://purl.uniprot.org/uniprot/D7CXA5 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/649638:TRAD_RS11415 ^@ http://purl.uniprot.org/uniprot/D7CSI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08430 ^@ http://purl.uniprot.org/uniprot/D7CQ35 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/649638:TRAD_RS09340 ^@ http://purl.uniprot.org/uniprot/D7CQL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06290 ^@ http://purl.uniprot.org/uniprot/D7CWI9 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/649638:TRAD_RS10385 ^@ http://purl.uniprot.org/uniprot/D7CRB9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS04250 ^@ http://purl.uniprot.org/uniprot/D7CU90 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/649638:TRAD_RS04910 ^@ http://purl.uniprot.org/uniprot/D7CV84 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/649638:TRAD_RS05970 ^@ http://purl.uniprot.org/uniprot/D7CW60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS08970 ^@ http://purl.uniprot.org/uniprot/D7CQE6 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/649638:TRAD_RS11315 ^@ http://purl.uniprot.org/uniprot/D7CSG5 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS15190 ^@ http://purl.uniprot.org/uniprot/D7CXL2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/649638:TRAD_RS01950 ^@ http://purl.uniprot.org/uniprot/D7CRN3 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/649638:TRAD_RS14180 ^@ http://purl.uniprot.org/uniprot/D7CVN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14275 ^@ http://purl.uniprot.org/uniprot/D7CVQ7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/649638:TRAD_RS07070 ^@ http://purl.uniprot.org/uniprot/D7CX40 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/649638:TRAD_RS01825 ^@ http://purl.uniprot.org/uniprot/D7CRK7 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/649638:TRAD_RS10835 ^@ http://purl.uniprot.org/uniprot/D7CRW5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS06200 ^@ http://purl.uniprot.org/uniprot/D7CWH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00350 ^@ http://purl.uniprot.org/uniprot/D7CX89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/649638:TRAD_RS03495 ^@ http://purl.uniprot.org/uniprot/D7CTH6 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/649638:TRAD_RS03805 ^@ http://purl.uniprot.org/uniprot/D7CU00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS08785 ^@ http://purl.uniprot.org/uniprot/D7CQA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS05315 ^@ http://purl.uniprot.org/uniprot/D7CVG5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/649638:TRAD_RS10695 ^@ http://purl.uniprot.org/uniprot/D7CRT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/649638:TRAD_RS11855 ^@ http://purl.uniprot.org/uniprot/D7CT26 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/649638:TRAD_RS00005 ^@ http://purl.uniprot.org/uniprot/D7CWQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/649638:TRAD_RS08160 ^@ http://purl.uniprot.org/uniprot/D7CYC6 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/649638:TRAD_RS05205 ^@ http://purl.uniprot.org/uniprot/D7CVE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/649638:TRAD_RS00210 ^@ http://purl.uniprot.org/uniprot/D7CWU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/649638:TRAD_RS12970 ^@ http://purl.uniprot.org/uniprot/D7CUC3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS06725 ^@ http://purl.uniprot.org/uniprot/D7CWW7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/649638:TRAD_RS10305 ^@ http://purl.uniprot.org/uniprot/D7CRA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS09755 ^@ http://purl.uniprot.org/uniprot/D7CQV0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS06445 ^@ http://purl.uniprot.org/uniprot/D7CWM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00920 ^@ http://purl.uniprot.org/uniprot/D7CXW0 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/649638:TRAD_RS15135 ^@ http://purl.uniprot.org/uniprot/D7CWG9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/649638:TRAD_RS05375 ^@ http://purl.uniprot.org/uniprot/D7CVH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/649638:TRAD_RS02485 ^@ http://purl.uniprot.org/uniprot/D7CS96 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/649638:TRAD_RS08740 ^@ http://purl.uniprot.org/uniprot/D7CQ96 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/649638:TRAD_RS07480 ^@ http://purl.uniprot.org/uniprot/D7CXM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS04525 ^@ http://purl.uniprot.org/uniprot/D7CUP6 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/649638:TRAD_RS13010 ^@ http://purl.uniprot.org/uniprot/D7CUD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS10850 ^@ http://purl.uniprot.org/uniprot/D7CRW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS01145 ^@ http://purl.uniprot.org/uniprot/D7CY05 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/649638:TRAD_RS14075 ^@ http://purl.uniprot.org/uniprot/D7CVL3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/649638:TRAD_RS03760 ^@ http://purl.uniprot.org/uniprot/D7CTN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS01845 ^@ http://purl.uniprot.org/uniprot/D7CRL2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS11185 ^@ http://purl.uniprot.org/uniprot/D7CSD9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/649638:TRAD_RS00115 ^@ http://purl.uniprot.org/uniprot/D7CWS4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/649638:TRAD_RS03135 ^@ http://purl.uniprot.org/uniprot/D7CSZ1 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/649638:TRAD_RS14760 ^@ http://purl.uniprot.org/uniprot/D7CWB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08320 ^@ http://purl.uniprot.org/uniprot/D7CYF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS08295 ^@ http://purl.uniprot.org/uniprot/D7CYF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/649638:TRAD_RS07605 ^@ http://purl.uniprot.org/uniprot/D7CXQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS05280 ^@ http://purl.uniprot.org/uniprot/D7CVF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/649638:TRAD_RS10000 ^@ http://purl.uniprot.org/uniprot/D7CQZ8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/649638:TRAD_RS07415 ^@ http://purl.uniprot.org/uniprot/D7CXL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS13920 ^@ http://purl.uniprot.org/uniprot/D7CV65 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/649638:TRAD_RS03720 ^@ http://purl.uniprot.org/uniprot/D7CTM4 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/649638:TRAD_RS02375 ^@ http://purl.uniprot.org/uniprot/D7CS74 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/649638:TRAD_RS00695 ^@ http://purl.uniprot.org/uniprot/D7CXF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/649638:TRAD_RS11010 ^@ http://purl.uniprot.org/uniprot/D7CS00 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/649638:TRAD_RS06855 ^@ http://purl.uniprot.org/uniprot/D7CWZ4 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/649638:TRAD_RS03410 ^@ http://purl.uniprot.org/uniprot/D7CTF9 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/649638:TRAD_RS14475 ^@ http://purl.uniprot.org/uniprot/D7CVU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS07910 ^@ http://purl.uniprot.org/uniprot/D7CY77 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/649638:TRAD_RS09180 ^@ http://purl.uniprot.org/uniprot/D7CQI6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/649638:TRAD_RS02235 ^@ http://purl.uniprot.org/uniprot/D7CS46 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/649638:TRAD_RS12525 ^@ http://purl.uniprot.org/uniprot/D7CTS3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/649638:TRAD_RS13350 ^@ http://purl.uniprot.org/uniprot/D7CUJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00025 ^@ http://purl.uniprot.org/uniprot/D7CWQ7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/649638:TRAD_RS00335 ^@ http://purl.uniprot.org/uniprot/D7CX86 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/649638:TRAD_RS11195 ^@ http://purl.uniprot.org/uniprot/D7CSE1 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/649638:TRAD_RS02565 ^@ http://purl.uniprot.org/uniprot/D7CSB3 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/649638:TRAD_RS06980 ^@ http://purl.uniprot.org/uniprot/D7CX20 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/649638:TRAD_RS14590 ^@ http://purl.uniprot.org/uniprot/D7CW81 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/649638:TRAD_RS13110 ^@ http://purl.uniprot.org/uniprot/D7CUF0 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/649638:TRAD_RS14110 ^@ http://purl.uniprot.org/uniprot/D7CVM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS11720 ^@ http://purl.uniprot.org/uniprot/D7CSP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07825 ^@ http://purl.uniprot.org/uniprot/D7CY60 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/649638:TRAD_RS15520 ^@ http://purl.uniprot.org/uniprot/D7CW78 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/649638:TRAD_RS02480 ^@ http://purl.uniprot.org/uniprot/D7CS95 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/649638:TRAD_RS11920 ^@ http://purl.uniprot.org/uniprot/D7CT39 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/649638:TRAD_RS04935 ^@ http://purl.uniprot.org/uniprot/D7CV89 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/649638:TRAD_RS00730 ^@ http://purl.uniprot.org/uniprot/D7CXF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS07805 ^@ http://purl.uniprot.org/uniprot/D7CY56 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS14545 ^@ http://purl.uniprot.org/uniprot/D7CVW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/649638:TRAD_RS04580 ^@ http://purl.uniprot.org/uniprot/D7CUQ7 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/649638:TRAD_RS01810 ^@ http://purl.uniprot.org/uniprot/D7CRK4 ^@ Similarity ^@ Belongs to the cytochrome b560 family. http://togogenome.org/gene/649638:TRAD_RS07450 ^@ http://purl.uniprot.org/uniprot/D7CXM2 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/649638:TRAD_RS07775 ^@ http://purl.uniprot.org/uniprot/D7CY50 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/649638:TRAD_RS12060 ^@ http://purl.uniprot.org/uniprot/D7CT68 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/649638:TRAD_RS11835 ^@ http://purl.uniprot.org/uniprot/D7CT22 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/649638:TRAD_RS00800 ^@ http://purl.uniprot.org/uniprot/D7CXT7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/649638:TRAD_RS15155 ^@ http://purl.uniprot.org/uniprot/D7CWN2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/649638:TRAD_RS12350 ^@ http://purl.uniprot.org/uniprot/D7CTP2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/649638:TRAD_RS05555 ^@ http://purl.uniprot.org/uniprot/D7CVX9 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/649638:TRAD_RS11190 ^@ http://purl.uniprot.org/uniprot/D7CSE0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/649638:TRAD_RS11385 ^@ http://purl.uniprot.org/uniprot/D7CSH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS04575 ^@ http://purl.uniprot.org/uniprot/D7CUQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS03775 ^@ http://purl.uniprot.org/uniprot/D7CTZ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01665 ^@ http://purl.uniprot.org/uniprot/D7CRH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/649638:TRAD_RS12345 ^@ http://purl.uniprot.org/uniprot/D7CTP1 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/649638:TRAD_RS03850 ^@ http://purl.uniprot.org/uniprot/D7CU10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13860 ^@ http://purl.uniprot.org/uniprot/D7CV53 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/649638:TRAD_RS02200 ^@ http://purl.uniprot.org/uniprot/D7CS39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/649638:TRAD_RS09670 ^@ http://purl.uniprot.org/uniprot/D7CQT4 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS04425 ^@ http://purl.uniprot.org/uniprot/D7CUM6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/649638:TRAD_RS14000 ^@ http://purl.uniprot.org/uniprot/D7CV80 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS08565 ^@ http://purl.uniprot.org/uniprot/D7CQ62 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/649638:TRAD_RS04880 ^@ http://purl.uniprot.org/uniprot/D7CUW5 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/649638:TRAD_RS13870 ^@ http://purl.uniprot.org/uniprot/D7CV55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13285 ^@ http://purl.uniprot.org/uniprot/D7CUI4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/649638:TRAD_RS12885 ^@ http://purl.uniprot.org/uniprot/D7CUA6 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/649638:TRAD_RS07935 ^@ http://purl.uniprot.org/uniprot/D7CY82 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/649638:TRAD_RS14120 ^@ http://purl.uniprot.org/uniprot/D7CVM2 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS00050 ^@ http://purl.uniprot.org/uniprot/D7CWR2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/649638:TRAD_RS10820 ^@ http://purl.uniprot.org/uniprot/D7CRW2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/649638:TRAD_RS13890 ^@ http://purl.uniprot.org/uniprot/D7CV59 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/649638:TRAD_RS14895 ^@ http://purl.uniprot.org/uniprot/D7CX84 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/649638:TRAD_RS00430 ^@ http://purl.uniprot.org/uniprot/D7CXA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/649638:TRAD_RS08505 ^@ http://purl.uniprot.org/uniprot/D7CQ50 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/649638:TRAD_RS14155 ^@ http://purl.uniprot.org/uniprot/D7CVN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/649638:TRAD_RS02095 ^@ http://purl.uniprot.org/uniprot/D7CRR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS05390 ^@ http://purl.uniprot.org/uniprot/D7CVI0 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/649638:TRAD_RS10620 ^@ http://purl.uniprot.org/uniprot/D7CRS2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/649638:TRAD_RS03770 ^@ http://purl.uniprot.org/uniprot/D7CTZ3 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/649638:TRAD_RS02035 ^@ http://purl.uniprot.org/uniprot/D7CRQ0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS01660 ^@ http://purl.uniprot.org/uniprot/D7CRH4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS09380 ^@ http://purl.uniprot.org/uniprot/D7CQM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/649638:TRAD_RS10325 ^@ http://purl.uniprot.org/uniprot/D7CRA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02935 ^@ http://purl.uniprot.org/uniprot/D7CSV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/649638:TRAD_RS05250 ^@ http://purl.uniprot.org/uniprot/D7CVF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/649638:TRAD_RS01080 ^@ http://purl.uniprot.org/uniprot/D7CXZ2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS06870 ^@ http://purl.uniprot.org/uniprot/D7CWZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/649638:TRAD_RS06260 ^@ http://purl.uniprot.org/uniprot/D7CWI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/649638:TRAD_RS14800 ^@ http://purl.uniprot.org/uniprot/D7CWC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS03460 ^@ http://purl.uniprot.org/uniprot/D7CTG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS07820 ^@ http://purl.uniprot.org/uniprot/D7CY59 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/649638:TRAD_RS10975 ^@ http://purl.uniprot.org/uniprot/D7CRZ3 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/649638:TRAD_RS11000 ^@ http://purl.uniprot.org/uniprot/D7CRZ8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/649638:TRAD_RS00240 ^@ http://purl.uniprot.org/uniprot/D7CX66 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/649638:TRAD_RS05515 ^@ http://purl.uniprot.org/uniprot/D7CVX2 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS08920 ^@ http://purl.uniprot.org/uniprot/D7CQD6 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS13065 ^@ http://purl.uniprot.org/uniprot/D7CUE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS14370 ^@ http://purl.uniprot.org/uniprot/D7CVS5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS01120 ^@ http://purl.uniprot.org/uniprot/D7CY00 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/649638:TRAD_RS04305 ^@ http://purl.uniprot.org/uniprot/D7CUA1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/649638:TRAD_RS05230 ^@ http://purl.uniprot.org/uniprot/D7CVE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/649638:TRAD_RS03875 ^@ http://purl.uniprot.org/uniprot/D7CU15 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS12895 ^@ http://purl.uniprot.org/uniprot/D7CUA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14860 ^@ http://purl.uniprot.org/uniprot/D7CWD4 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/649638:TRAD_RS01500 ^@ http://purl.uniprot.org/uniprot/D7CR33 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/649638:TRAD_RS06900 ^@ http://purl.uniprot.org/uniprot/D7CX03 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/649638:TRAD_RS05380 ^@ http://purl.uniprot.org/uniprot/D7CVH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/649638:TRAD_RS08495 ^@ http://purl.uniprot.org/uniprot/D7CQ48 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/649638:TRAD_RS00180 ^@ http://purl.uniprot.org/uniprot/D7CWT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/649638:TRAD_RS13760 ^@ http://purl.uniprot.org/uniprot/D7CV34 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS09165 ^@ http://purl.uniprot.org/uniprot/D7CQI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS13820 ^@ http://purl.uniprot.org/uniprot/D7CV46 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/649638:TRAD_RS06970 ^@ http://purl.uniprot.org/uniprot/D7CX18 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS12985 ^@ http://purl.uniprot.org/uniprot/D7CUC5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/649638:TRAD_RS03540 ^@ http://purl.uniprot.org/uniprot/D7CTI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS04770 ^@ http://purl.uniprot.org/uniprot/D7CUU6 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/649638:TRAD_RS02355 ^@ http://purl.uniprot.org/uniprot/D7CS70 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/649638:TRAD_RS10210 ^@ http://purl.uniprot.org/uniprot/D7CR86 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/649638:TRAD_RS02540 ^@ http://purl.uniprot.org/uniprot/D7CSA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/649638:TRAD_RS04845 ^@ http://purl.uniprot.org/uniprot/D7CUV8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/649638:TRAD_RS12870 ^@ http://purl.uniprot.org/uniprot/D7CTZ1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS03610 ^@ http://purl.uniprot.org/uniprot/D7CTK2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/649638:TRAD_RS02670 ^@ http://purl.uniprot.org/uniprot/D7CSD4 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/649638:TRAD_RS05320 ^@ http://purl.uniprot.org/uniprot/D7CVG6 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/649638:TRAD_RS04540 ^@ http://purl.uniprot.org/uniprot/D7CUP9 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/649638:TRAD_RS13270 ^@ http://purl.uniprot.org/uniprot/D7CUI1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/649638:TRAD_RS02265 ^@ http://purl.uniprot.org/uniprot/D7CS52 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/649638:TRAD_RS10265 ^@ http://purl.uniprot.org/uniprot/D7CR96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS12845 ^@ http://purl.uniprot.org/uniprot/D7CTY4 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS06600 ^@ http://purl.uniprot.org/uniprot/D7CWQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS09420 ^@ http://purl.uniprot.org/uniprot/D7CQN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS10775 ^@ http://purl.uniprot.org/uniprot/D7CRV4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/649638:TRAD_RS08905 ^@ http://purl.uniprot.org/uniprot/D7CQD3 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/649638:TRAD_RS12545 ^@ http://purl.uniprot.org/uniprot/D7CTS5 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS13905 ^@ http://purl.uniprot.org/uniprot/D7CV62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/649638:TRAD_RS00325 ^@ http://purl.uniprot.org/uniprot/D7CX83 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01490 ^@ http://purl.uniprot.org/uniprot/D7CR31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01175 ^@ http://purl.uniprot.org/uniprot/D7CY11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS01005 ^@ http://purl.uniprot.org/uniprot/D7CXX7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS05540 ^@ http://purl.uniprot.org/uniprot/D7CVX6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/649638:TRAD_RS10870 ^@ http://purl.uniprot.org/uniprot/D7CRX2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS00390 ^@ http://purl.uniprot.org/uniprot/D7CX96 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/649638:TRAD_RS01150 ^@ http://purl.uniprot.org/uniprot/D7CY06 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/649638:TRAD_RS08985 ^@ http://purl.uniprot.org/uniprot/D7CQE9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/649638:TRAD_RS03485 ^@ http://purl.uniprot.org/uniprot/D7CTH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07110 ^@ http://purl.uniprot.org/uniprot/D7CX49 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/649638:TRAD_RS06285 ^@ http://purl.uniprot.org/uniprot/D7CWI8 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/649638:TRAD_RS01360 ^@ http://purl.uniprot.org/uniprot/D7CR05 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/649638:TRAD_RS05725 ^@ http://purl.uniprot.org/uniprot/D7CW13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/649638:TRAD_RS14235 ^@ http://purl.uniprot.org/uniprot/D7CVP8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS06395 ^@ http://purl.uniprot.org/uniprot/D7CWL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/649638:TRAD_RS05180 ^@ http://purl.uniprot.org/uniprot/D7CVD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/649638:TRAD_RS01740 ^@ http://purl.uniprot.org/uniprot/D7CRJ0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/649638:TRAD_RS14815 ^@ http://purl.uniprot.org/uniprot/D7CWC5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS00775 ^@ http://purl.uniprot.org/uniprot/D7CXT2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/649638:TRAD_RS13435 ^@ http://purl.uniprot.org/uniprot/D7CUL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS10070 ^@ http://purl.uniprot.org/uniprot/D7CR58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11170 ^@ http://purl.uniprot.org/uniprot/D7CSD6 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/649638:TRAD_RS08780 ^@ http://purl.uniprot.org/uniprot/D7CQA5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS01405 ^@ http://purl.uniprot.org/uniprot/D7CR14 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS00040 ^@ http://purl.uniprot.org/uniprot/D7CWR0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/649638:TRAD_RS06085 ^@ http://purl.uniprot.org/uniprot/D7CWE8 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/649638:TRAD_RS09790 ^@ http://purl.uniprot.org/uniprot/D7CQV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS06645 ^@ http://purl.uniprot.org/uniprot/D7CWV0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS03600 ^@ http://purl.uniprot.org/uniprot/D7CTK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS15270 ^@ http://purl.uniprot.org/uniprot/D7CQD0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/649638:TRAD_RS07855 ^@ http://purl.uniprot.org/uniprot/D7CY66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/649638:TRAD_RS08375 ^@ http://purl.uniprot.org/uniprot/D7CQ24 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS09430 ^@ http://purl.uniprot.org/uniprot/D7CQN6 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/649638:TRAD_RS14595 ^@ http://purl.uniprot.org/uniprot/D7CW82 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/649638:TRAD_RS01655 ^@ http://purl.uniprot.org/uniprot/D7CRH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/649638:TRAD_RS11695 ^@ http://purl.uniprot.org/uniprot/D7CSN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07865 ^@ http://purl.uniprot.org/uniprot/D7CY68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS00030 ^@ http://purl.uniprot.org/uniprot/D7CWQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/649638:TRAD_RS00020 ^@ http://purl.uniprot.org/uniprot/D7CWQ6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/649638:TRAD_RS08770 ^@ http://purl.uniprot.org/uniprot/D7CQA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/649638:TRAD_RS10405 ^@ http://purl.uniprot.org/uniprot/D7CRC3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/649638:TRAD_RS11830 ^@ http://purl.uniprot.org/uniprot/D7CT21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/649638:TRAD_RS12365 ^@ http://purl.uniprot.org/uniprot/D7CTP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/649638:TRAD_RS06295 ^@ http://purl.uniprot.org/uniprot/D7CWJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS08290 ^@ http://purl.uniprot.org/uniprot/D7CYF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/649638:TRAD_RS04960 ^@ http://purl.uniprot.org/uniprot/D7CV94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS01260 ^@ http://purl.uniprot.org/uniprot/D7CY25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07780 ^@ http://purl.uniprot.org/uniprot/D7CY51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS04965 ^@ http://purl.uniprot.org/uniprot/D7CV95 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/649638:TRAD_RS12665 ^@ http://purl.uniprot.org/uniprot/D7CTU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11800 ^@ http://purl.uniprot.org/uniprot/D7CT15 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS07730 ^@ http://purl.uniprot.org/uniprot/D7CXS8 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/649638:TRAD_RS08760 ^@ http://purl.uniprot.org/uniprot/D7CQA0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/649638:TRAD_RS01310 ^@ http://purl.uniprot.org/uniprot/D7CY35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06955 ^@ http://purl.uniprot.org/uniprot/D7CX15 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS05245 ^@ http://purl.uniprot.org/uniprot/D7CVF0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/649638:TRAD_RS07050 ^@ http://purl.uniprot.org/uniprot/D7CX35 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/649638:TRAD_RS09535 ^@ http://purl.uniprot.org/uniprot/D7CQQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11215 ^@ http://purl.uniprot.org/uniprot/D7CSE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS12475 ^@ http://purl.uniprot.org/uniprot/D7CTR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS13445 ^@ http://purl.uniprot.org/uniprot/D7CUX1 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/649638:TRAD_RS08265 ^@ http://purl.uniprot.org/uniprot/D7CYE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS01160 ^@ http://purl.uniprot.org/uniprot/D7CY08 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/649638:TRAD_RS02860 ^@ http://purl.uniprot.org/uniprot/D7CST7 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/649638:TRAD_RS08415 ^@ http://purl.uniprot.org/uniprot/D7CQ32 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/649638:TRAD_RS07615 ^@ http://purl.uniprot.org/uniprot/D7CXQ5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS11850 ^@ http://purl.uniprot.org/uniprot/D7CT25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/649638:TRAD_RS05990 ^@ http://purl.uniprot.org/uniprot/D7CW64 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/649638:TRAD_RS04705 ^@ http://purl.uniprot.org/uniprot/D7CUT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS07005 ^@ http://purl.uniprot.org/uniprot/D7CX25 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/649638:TRAD_RS06840 ^@ http://purl.uniprot.org/uniprot/D7CWZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS08285 ^@ http://purl.uniprot.org/uniprot/D7CYF0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/649638:TRAD_RS04520 ^@ http://purl.uniprot.org/uniprot/D7CUP5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/649638:TRAD_RS13575 ^@ http://purl.uniprot.org/uniprot/D7CUZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00340 ^@ http://purl.uniprot.org/uniprot/D7CX87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/649638:TRAD_RS10175 ^@ http://purl.uniprot.org/uniprot/D7CR79 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/649638:TRAD_RS01905 ^@ http://purl.uniprot.org/uniprot/D7CRM4 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/649638:TRAD_RS14965 ^@ http://purl.uniprot.org/uniprot/D7CRG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/649638:TRAD_RS10445 ^@ http://purl.uniprot.org/uniprot/D7CRD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/649638:TRAD_RS13000 ^@ http://purl.uniprot.org/uniprot/D7CUC8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/649638:TRAD_RS04145 ^@ http://purl.uniprot.org/uniprot/D7CU69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS05615 ^@ http://purl.uniprot.org/uniprot/D7CVZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS00480 ^@ http://purl.uniprot.org/uniprot/D7CXB0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/649638:TRAD_RS06895 ^@ http://purl.uniprot.org/uniprot/D7CX02 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. http://togogenome.org/gene/649638:TRAD_RS04545 ^@ http://purl.uniprot.org/uniprot/D7CUQ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/649638:TRAD_RS13635 ^@ http://purl.uniprot.org/uniprot/D7CV09 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS08170 ^@ http://purl.uniprot.org/uniprot/D7CYC8 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/649638:TRAD_RS02245 ^@ http://purl.uniprot.org/uniprot/D7CS48 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/649638:TRAD_RS01045 ^@ http://purl.uniprot.org/uniprot/D7CXY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/649638:TRAD_RS08165 ^@ http://purl.uniprot.org/uniprot/D7CYC7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS13365 ^@ http://purl.uniprot.org/uniprot/D7CUJ9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS13765 ^@ http://purl.uniprot.org/uniprot/D7CV35 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/649638:TRAD_RS06070 ^@ http://purl.uniprot.org/uniprot/D7CWE4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/649638:TRAD_RS11910 ^@ http://purl.uniprot.org/uniprot/D7CT37 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/649638:TRAD_RS07760 ^@ http://purl.uniprot.org/uniprot/D7CY47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11025 ^@ http://purl.uniprot.org/uniprot/D7CS03 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/649638:TRAD_RS09525 ^@ http://purl.uniprot.org/uniprot/D7CQQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS11500 ^@ http://purl.uniprot.org/uniprot/D7CSK2 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/649638:TRAD_RS11670 ^@ http://purl.uniprot.org/uniprot/D7CSN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS04740 ^@ http://purl.uniprot.org/uniprot/D7CUT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS07430 ^@ http://purl.uniprot.org/uniprot/D7CXL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/649638:TRAD_RS00955 ^@ http://purl.uniprot.org/uniprot/D7CXW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07590 ^@ http://purl.uniprot.org/uniprot/D7CXP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02790 ^@ http://purl.uniprot.org/uniprot/D7CSS5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/649638:TRAD_RS00940 ^@ http://purl.uniprot.org/uniprot/D7CXW4 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/649638:TRAD_RS02780 ^@ http://purl.uniprot.org/uniprot/D7CSS3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/649638:TRAD_RS00830 ^@ http://purl.uniprot.org/uniprot/D7CXU3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/649638:TRAD_RS13345 ^@ http://purl.uniprot.org/uniprot/D7CUJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS02820 ^@ http://purl.uniprot.org/uniprot/D7CST0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08110 ^@ http://purl.uniprot.org/uniprot/D7CYB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS02800 ^@ http://purl.uniprot.org/uniprot/D7CSS6 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/649638:TRAD_RS11590 ^@ http://purl.uniprot.org/uniprot/D7CSL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/649638:TRAD_RS11300 ^@ http://purl.uniprot.org/uniprot/D7CSG2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/649638:TRAD_RS12925 ^@ http://purl.uniprot.org/uniprot/D7CUB4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS13410 ^@ http://purl.uniprot.org/uniprot/D7CUK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10890 ^@ http://purl.uniprot.org/uniprot/D7CRX6 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/649638:TRAD_RS10535 ^@ http://purl.uniprot.org/uniprot/D7CRE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS01395 ^@ http://purl.uniprot.org/uniprot/D7CR12 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/649638:TRAD_RS12205 ^@ http://purl.uniprot.org/uniprot/D7CT98 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/649638:TRAD_RS10145 ^@ http://purl.uniprot.org/uniprot/D7CR73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS05490 ^@ http://purl.uniprot.org/uniprot/D7CVW7 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS00120 ^@ http://purl.uniprot.org/uniprot/D7CWS5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/649638:TRAD_RS03735 ^@ http://purl.uniprot.org/uniprot/D7CTM7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/649638:TRAD_RS13605 ^@ http://purl.uniprot.org/uniprot/D7CV03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/649638:TRAD_RS08030 ^@ http://purl.uniprot.org/uniprot/D7CYA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/649638:TRAD_RS01545 ^@ http://purl.uniprot.org/uniprot/D7CR42 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/649638:TRAD_RS02215 ^@ http://purl.uniprot.org/uniprot/D7CS42 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/649638:TRAD_RS07585 ^@ http://purl.uniprot.org/uniprot/D7CXP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS12300 ^@ http://purl.uniprot.org/uniprot/D7CTB6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/649638:TRAD_RS03655 ^@ http://purl.uniprot.org/uniprot/D7CTL1 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/649638:TRAD_RS04045 ^@ http://purl.uniprot.org/uniprot/D7CU48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/649638:TRAD_RS02675 ^@ http://purl.uniprot.org/uniprot/D7CSD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family. BdbC subfamily.|||Cell membrane|||Membrane|||Required for disulfide bond formation in some proteins. http://togogenome.org/gene/649638:TRAD_RS03855 ^@ http://purl.uniprot.org/uniprot/D7CU11 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/649638:TRAD_RS12920 ^@ http://purl.uniprot.org/uniprot/D7CUB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS03280 ^@ http://purl.uniprot.org/uniprot/D7CTD3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/649638:TRAD_RS00015 ^@ http://purl.uniprot.org/uniprot/D7CWQ5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/649638:TRAD_RS06695 ^@ http://purl.uniprot.org/uniprot/D7CWW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/649638:TRAD_RS03085 ^@ http://purl.uniprot.org/uniprot/D7CSR8 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/649638:TRAD_RS04555 ^@ http://purl.uniprot.org/uniprot/D7CUQ2 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/649638:TRAD_RS01955 ^@ http://purl.uniprot.org/uniprot/D7CRN4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/649638:TRAD_RS00260 ^@ http://purl.uniprot.org/uniprot/D7CX70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/649638:TRAD_RS05420 ^@ http://purl.uniprot.org/uniprot/D7CVI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS13665 ^@ http://purl.uniprot.org/uniprot/D7CV15 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/649638:TRAD_RS00315 ^@ http://purl.uniprot.org/uniprot/D7CX81 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/649638:TRAD_RS03120 ^@ http://purl.uniprot.org/uniprot/D7CSY8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/649638:TRAD_RS08885 ^@ http://purl.uniprot.org/uniprot/D7CQC9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/649638:TRAD_RS14400 ^@ http://purl.uniprot.org/uniprot/D7CVT2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS13990 ^@ http://purl.uniprot.org/uniprot/D7CV78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS06540 ^@ http://purl.uniprot.org/uniprot/D7CWN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS04180 ^@ http://purl.uniprot.org/uniprot/D7CU76 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS08895 ^@ http://purl.uniprot.org/uniprot/D7CQD1 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/649638:TRAD_RS09475 ^@ http://purl.uniprot.org/uniprot/D7CQP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS09320 ^@ http://purl.uniprot.org/uniprot/D7CQL3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS07345 ^@ http://purl.uniprot.org/uniprot/D7CXK2 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/649638:TRAD_RS08305 ^@ http://purl.uniprot.org/uniprot/D7CYF4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/649638:TRAD_RS06545 ^@ http://purl.uniprot.org/uniprot/D7CWP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS13745 ^@ http://purl.uniprot.org/uniprot/D7CV31 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/649638:TRAD_RS05195 ^@ http://purl.uniprot.org/uniprot/D7CVE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/649638:TRAD_RS12360 ^@ http://purl.uniprot.org/uniprot/D7CTP4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/649638:TRAD_RS10895 ^@ http://purl.uniprot.org/uniprot/D7CRX7 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/649638:TRAD_RS07790 ^@ http://purl.uniprot.org/uniprot/D7CY53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS15185 ^@ http://purl.uniprot.org/uniprot/D7CXL0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/649638:TRAD_RS12165 ^@ http://purl.uniprot.org/uniprot/D7CT89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS12740 ^@ http://purl.uniprot.org/uniprot/D7CTW4 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/649638:TRAD_RS07205 ^@ http://purl.uniprot.org/uniprot/D7CXH4 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/649638:TRAD_RS00150 ^@ http://purl.uniprot.org/uniprot/D7CWT1 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/649638:TRAD_RS03660 ^@ http://purl.uniprot.org/uniprot/D7CTL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/649638:TRAD_RS07620 ^@ http://purl.uniprot.org/uniprot/D7CXQ6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS13490 ^@ http://purl.uniprot.org/uniprot/D7CUY0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS09700 ^@ http://purl.uniprot.org/uniprot/D7CQU0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS12940 ^@ http://purl.uniprot.org/uniprot/D7CUB7 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/649638:TRAD_RS11725 ^@ http://purl.uniprot.org/uniprot/D7CSP4 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/649638:TRAD_RS05185 ^@ http://purl.uniprot.org/uniprot/D7CVD8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS03440 ^@ http://purl.uniprot.org/uniprot/D7CTG5 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/649638:TRAD_RS03780 ^@ http://purl.uniprot.org/uniprot/D7CTZ5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/649638:TRAD_RS07470 ^@ http://purl.uniprot.org/uniprot/D7CXM6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/649638:TRAD_RS14485 ^@ http://purl.uniprot.org/uniprot/D7CVU9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/649638:TRAD_RS12125 ^@ http://purl.uniprot.org/uniprot/D7CT81 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/649638:TRAD_RS04135 ^@ http://purl.uniprot.org/uniprot/D7CU67 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/649638:TRAD_RS07705 ^@ http://purl.uniprot.org/uniprot/D7CXS3 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS12180 ^@ http://purl.uniprot.org/uniprot/D7CT93 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/649638:TRAD_RS04530 ^@ http://purl.uniprot.org/uniprot/D7CUP7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS07255 ^@ http://purl.uniprot.org/uniprot/D7CXI4 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/649638:TRAD_RS05825 ^@ http://purl.uniprot.org/uniprot/D7CW34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS02365 ^@ http://purl.uniprot.org/uniprot/D7CS72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS04240 ^@ http://purl.uniprot.org/uniprot/D7CU88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/649638:TRAD_RS00130 ^@ http://purl.uniprot.org/uniprot/D7CWS7 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/649638:TRAD_RS09825 ^@ http://purl.uniprot.org/uniprot/D7CQW4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/649638:TRAD_RS05910 ^@ http://purl.uniprot.org/uniprot/D7CW51 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS11240 ^@ http://purl.uniprot.org/uniprot/D7CSF0 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/649638:TRAD_RS14520 ^@ http://purl.uniprot.org/uniprot/D7CVV6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/649638:TRAD_RS04205 ^@ http://purl.uniprot.org/uniprot/D7CU81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02360 ^@ http://purl.uniprot.org/uniprot/D7CS71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02955 ^@ http://purl.uniprot.org/uniprot/D7CSV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02950 ^@ http://purl.uniprot.org/uniprot/D7CSV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS05015 ^@ http://purl.uniprot.org/uniprot/D7CVA5 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/649638:TRAD_RS05575 ^@ http://purl.uniprot.org/uniprot/D7CVY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS01515 ^@ http://purl.uniprot.org/uniprot/D7CR36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS05080 ^@ http://purl.uniprot.org/uniprot/D7CVB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS11865 ^@ http://purl.uniprot.org/uniprot/D7CT28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS04210 ^@ http://purl.uniprot.org/uniprot/D7CU82 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/649638:TRAD_RS09960 ^@ http://purl.uniprot.org/uniprot/D7CQZ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS02155 ^@ http://purl.uniprot.org/uniprot/D7CS31 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/649638:TRAD_RS03845 ^@ http://purl.uniprot.org/uniprot/D7CU09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS06365 ^@ http://purl.uniprot.org/uniprot/D7CWK4 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/649638:TRAD_RS10630 ^@ http://purl.uniprot.org/uniprot/D7CRS4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/649638:TRAD_RS03145 ^@ http://purl.uniprot.org/uniprot/D7CSZ3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/649638:TRAD_RS03625 ^@ http://purl.uniprot.org/uniprot/D7CTK5 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/649638:TRAD_RS12950 ^@ http://purl.uniprot.org/uniprot/D7CUB9 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS00235 ^@ http://purl.uniprot.org/uniprot/D7CX65 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/649638:TRAD_RS14630 ^@ http://purl.uniprot.org/uniprot/D7CW88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal/bacterial/fungal opsin family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS09675 ^@ http://purl.uniprot.org/uniprot/D7CQT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS06500 ^@ http://purl.uniprot.org/uniprot/D7CWN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/649638:TRAD_RS05240 ^@ http://purl.uniprot.org/uniprot/D7CVE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/649638:TRAD_RS01650 ^@ http://purl.uniprot.org/uniprot/D7CRH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/649638:TRAD_RS04930 ^@ http://purl.uniprot.org/uniprot/D7CV88 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS06255 ^@ http://purl.uniprot.org/uniprot/D7CWI2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/649638:TRAD_RS02330 ^@ http://purl.uniprot.org/uniprot/D7CS65 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/649638:TRAD_RS02225 ^@ http://purl.uniprot.org/uniprot/D7CS44 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS00850 ^@ http://purl.uniprot.org/uniprot/D7CXU7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/649638:TRAD_RS08380 ^@ http://purl.uniprot.org/uniprot/D7CQ25 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/649638:TRAD_RS03835 ^@ http://purl.uniprot.org/uniprot/D7CU06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS09445 ^@ http://purl.uniprot.org/uniprot/D7CQN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS03420 ^@ http://purl.uniprot.org/uniprot/D7CTG1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/649638:TRAD_RS06310 ^@ http://purl.uniprot.org/uniprot/D7CWJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06850 ^@ http://purl.uniprot.org/uniprot/D7CWZ3 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/649638:TRAD_RS05340 ^@ http://purl.uniprot.org/uniprot/D7CVH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08020 ^@ http://purl.uniprot.org/uniprot/D7CY99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS00410 ^@ http://purl.uniprot.org/uniprot/D7CX97 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/649638:TRAD_RS05170 ^@ http://purl.uniprot.org/uniprot/D7CTP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/649638:TRAD_RS13985 ^@ http://purl.uniprot.org/uniprot/D7CV77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06675 ^@ http://purl.uniprot.org/uniprot/D7CWV7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/649638:TRAD_RS01875 ^@ http://purl.uniprot.org/uniprot/D7CRL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/649638:TRAD_RS04200 ^@ http://purl.uniprot.org/uniprot/D7CU80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS13470 ^@ http://purl.uniprot.org/uniprot/D7CUX6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/649638:TRAD_RS09745 ^@ http://purl.uniprot.org/uniprot/D7CQU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS00035 ^@ http://purl.uniprot.org/uniprot/D7CWQ9 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/649638:TRAD_RS12850 ^@ http://purl.uniprot.org/uniprot/D7CTY5 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS06375 ^@ http://purl.uniprot.org/uniprot/D7CWK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/649638:TRAD_RS00360 ^@ http://purl.uniprot.org/uniprot/D7CX91 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/649638:TRAD_RS12485 ^@ http://purl.uniprot.org/uniprot/D7CTR5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/649638:TRAD_RS14035 ^@ http://purl.uniprot.org/uniprot/D7CVK4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01075 ^@ http://purl.uniprot.org/uniprot/D7CXZ1 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/649638:TRAD_RS11555 ^@ http://purl.uniprot.org/uniprot/D7CSL2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS14795 ^@ http://purl.uniprot.org/uniprot/D7CWC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/649638:TRAD_RS01025 ^@ http://purl.uniprot.org/uniprot/D7CXY1 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS11780 ^@ http://purl.uniprot.org/uniprot/D7CT11 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS03215 ^@ http://purl.uniprot.org/uniprot/D7CTC0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/649638:TRAD_RS05140 ^@ http://purl.uniprot.org/uniprot/D7CVC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS03690 ^@ http://purl.uniprot.org/uniprot/D7CTL9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/649638:TRAD_RS12960 ^@ http://purl.uniprot.org/uniprot/D7CUC1 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/649638:TRAD_RS09315 ^@ http://purl.uniprot.org/uniprot/D7CQL2 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/649638:TRAD_RS02755 ^@ http://purl.uniprot.org/uniprot/D7CSR8 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/649638:TRAD_RS16270 ^@ http://purl.uniprot.org/uniprot/D7CW44 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS05330 ^@ http://purl.uniprot.org/uniprot/D7CVG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/649638:TRAD_RS06040 ^@ http://purl.uniprot.org/uniprot/D7CW74 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/649638:TRAD_RS05650 ^@ http://purl.uniprot.org/uniprot/D7CVZ9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/649638:TRAD_RS06760 ^@ http://purl.uniprot.org/uniprot/D7CWX4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS02855 ^@ http://purl.uniprot.org/uniprot/D7CST6 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/649638:TRAD_RS08665 ^@ http://purl.uniprot.org/uniprot/D7CQ82 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS01415 ^@ http://purl.uniprot.org/uniprot/D7CR16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS07695 ^@ http://purl.uniprot.org/uniprot/D7CXS1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/649638:TRAD_RS12945 ^@ http://purl.uniprot.org/uniprot/D7CUB8 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs. http://togogenome.org/gene/649638:TRAD_RS11265 ^@ http://purl.uniprot.org/uniprot/D7CSF5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/649638:TRAD_RS13750 ^@ http://purl.uniprot.org/uniprot/D7CV32 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/649638:TRAD_RS01765 ^@ http://purl.uniprot.org/uniprot/D7CRJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS01480 ^@ http://purl.uniprot.org/uniprot/D7CR29 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS07035 ^@ http://purl.uniprot.org/uniprot/D7CX31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS02500 ^@ http://purl.uniprot.org/uniprot/D7CSA0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/649638:TRAD_RS12160 ^@ http://purl.uniprot.org/uniprot/D7CT88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS00815 ^@ http://purl.uniprot.org/uniprot/D7CXU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS10955 ^@ http://purl.uniprot.org/uniprot/D7CRY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/649638:TRAD_RS12560 ^@ http://purl.uniprot.org/uniprot/D7CTS8 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/649638:TRAD_RS05495 ^@ http://purl.uniprot.org/uniprot/D7CVW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/649638:TRAD_RS00810 ^@ http://purl.uniprot.org/uniprot/D7CXT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS15410 ^@ http://purl.uniprot.org/uniprot/D7CT82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14365 ^@ http://purl.uniprot.org/uniprot/D7CVS4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS12055 ^@ http://purl.uniprot.org/uniprot/D7CT67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS05175 ^@ http://purl.uniprot.org/uniprot/D7CVD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS01320 ^@ http://purl.uniprot.org/uniprot/D7CY37 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS14785 ^@ http://purl.uniprot.org/uniprot/D7CWB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS04070 ^@ http://purl.uniprot.org/uniprot/D7CU54 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/649638:TRAD_RS14970 ^@ http://purl.uniprot.org/uniprot/D7CRL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/649638:TRAD_RS09990 ^@ http://purl.uniprot.org/uniprot/D7CQZ6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/649638:TRAD_RS04620 ^@ http://purl.uniprot.org/uniprot/D7CUR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS08800 ^@ http://purl.uniprot.org/uniprot/D7CQB1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/649638:TRAD_RS06425 ^@ http://purl.uniprot.org/uniprot/D7CWL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS09470 ^@ http://purl.uniprot.org/uniprot/D7CQP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS16295 ^@ http://purl.uniprot.org/uniprot/D7CWN4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/649638:TRAD_RS06880 ^@ http://purl.uniprot.org/uniprot/D7CWZ9 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/649638:TRAD_RS02435 ^@ http://purl.uniprot.org/uniprot/D7CS86 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/649638:TRAD_RS05580 ^@ http://purl.uniprot.org/uniprot/D7CVY4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/649638:TRAD_RS01975 ^@ http://purl.uniprot.org/uniprot/D7CRN8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/649638:TRAD_RS04710 ^@ http://purl.uniprot.org/uniprot/D7CUT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS08420 ^@ http://purl.uniprot.org/uniprot/D7CQ33 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/649638:TRAD_RS08195 ^@ http://purl.uniprot.org/uniprot/D7CYD2 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/649638:TRAD_RS00230 ^@ http://purl.uniprot.org/uniprot/D7CX64 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/649638:TRAD_RS05680 ^@ http://purl.uniprot.org/uniprot/D7CW04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS09210 ^@ http://purl.uniprot.org/uniprot/D7CQJ2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/649638:TRAD_RS02885 ^@ http://purl.uniprot.org/uniprot/D7CSU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS00640 ^@ http://purl.uniprot.org/uniprot/D7CXE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS10585 ^@ http://purl.uniprot.org/uniprot/D7CRF5 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/649638:TRAD_RS13900 ^@ http://purl.uniprot.org/uniprot/D7CV61 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS10845 ^@ http://purl.uniprot.org/uniprot/D7CRW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS06160 ^@ http://purl.uniprot.org/uniprot/D7CWG4 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/649638:TRAD_RS04235 ^@ http://purl.uniprot.org/uniprot/D7CU87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS09800 ^@ http://purl.uniprot.org/uniprot/D7CQV9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/649638:TRAD_RS05215 ^@ http://purl.uniprot.org/uniprot/D7CVE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS03235 ^@ http://purl.uniprot.org/uniprot/D7CTC4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/649638:TRAD_RS14855 ^@ http://purl.uniprot.org/uniprot/D7CWD3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/649638:TRAD_RS04220 ^@ http://purl.uniprot.org/uniprot/D7CU84 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS05570 ^@ http://purl.uniprot.org/uniprot/D7CVY2 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/649638:TRAD_RS00835 ^@ http://purl.uniprot.org/uniprot/D7CXU4 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/649638:TRAD_RS11345 ^@ http://purl.uniprot.org/uniprot/D7CSH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS03705 ^@ http://purl.uniprot.org/uniprot/D7CTM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS09595 ^@ http://purl.uniprot.org/uniprot/D7CQR8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/649638:TRAD_RS00995 ^@ http://purl.uniprot.org/uniprot/D7CXX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/649638:TRAD_RS00875 ^@ http://purl.uniprot.org/uniprot/D7CS03 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/649638:TRAD_RS11980 ^@ http://purl.uniprot.org/uniprot/D7CT51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS11775 ^@ http://purl.uniprot.org/uniprot/D7CT10 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS10675 ^@ http://purl.uniprot.org/uniprot/D7CRT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS08655 ^@ http://purl.uniprot.org/uniprot/D7CQ80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS02045 ^@ http://purl.uniprot.org/uniprot/D7CRQ2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/649638:TRAD_RS04030 ^@ http://purl.uniprot.org/uniprot/D7CU45 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/649638:TRAD_RS10495 ^@ http://purl.uniprot.org/uniprot/D7CRD8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/649638:TRAD_RS02880 ^@ http://purl.uniprot.org/uniprot/D7CSU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS08795 ^@ http://purl.uniprot.org/uniprot/D7CQA8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS04245 ^@ http://purl.uniprot.org/uniprot/D7CU89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS08230 ^@ http://purl.uniprot.org/uniprot/D7CYD9 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/649638:TRAD_RS01940 ^@ http://purl.uniprot.org/uniprot/D7CRN1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/649638:TRAD_RS06665 ^@ http://purl.uniprot.org/uniprot/D7CWV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/649638:TRAD_RS04745 ^@ http://purl.uniprot.org/uniprot/D7CUU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS11275 ^@ http://purl.uniprot.org/uniprot/D7CSF7 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/649638:TRAD_RS06700 ^@ http://purl.uniprot.org/uniprot/D7CWW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/649638:TRAD_RS00200 ^@ http://purl.uniprot.org/uniprot/D7CWU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11445 ^@ http://purl.uniprot.org/uniprot/D7CSJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS07375 ^@ http://purl.uniprot.org/uniprot/D7CXK8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/649638:TRAD_RS08335 ^@ http://purl.uniprot.org/uniprot/D7CQ16 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS02665 ^@ http://purl.uniprot.org/uniprot/D7CSD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS06800 ^@ http://purl.uniprot.org/uniprot/D7CWY3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/649638:TRAD_RS09455 ^@ http://purl.uniprot.org/uniprot/D7CQP1 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/649638:TRAD_RS05480 ^@ http://purl.uniprot.org/uniprot/D7CVW5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/649638:TRAD_RS10270 ^@ http://purl.uniprot.org/uniprot/D7CR97 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS09995 ^@ http://purl.uniprot.org/uniprot/D7CQZ7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/649638:TRAD_RS12730 ^@ http://purl.uniprot.org/uniprot/D7CTW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS03230 ^@ http://purl.uniprot.org/uniprot/D7CTC3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/649638:TRAD_RS08040 ^@ http://purl.uniprot.org/uniprot/D7CYA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/649638:TRAD_RS12620 ^@ http://purl.uniprot.org/uniprot/D7CTU3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/649638:TRAD_RS13225 ^@ http://purl.uniprot.org/uniprot/D7CUH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS00550 ^@ http://purl.uniprot.org/uniprot/D7CXC3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/649638:TRAD_RS13945 ^@ http://purl.uniprot.org/uniprot/D7CV70 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/649638:TRAD_RS01470 ^@ http://purl.uniprot.org/uniprot/D7CR27 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/649638:TRAD_RS02300 ^@ http://purl.uniprot.org/uniprot/D7CS59 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/649638:TRAD_RS04090 ^@ http://purl.uniprot.org/uniprot/D7CU58 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS01820 ^@ http://purl.uniprot.org/uniprot/D7CRK6 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/649638:TRAD_RS01900 ^@ http://purl.uniprot.org/uniprot/D7CRM3 ^@ Similarity ^@ Belongs to the QNG1 protein family. http://togogenome.org/gene/649638:TRAD_RS10500 ^@ http://purl.uniprot.org/uniprot/D7CRD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS07905 ^@ http://purl.uniprot.org/uniprot/D7CY76 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS09545 ^@ http://purl.uniprot.org/uniprot/D7CQQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/649638:TRAD_RS12340 ^@ http://purl.uniprot.org/uniprot/D7CTP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/649638:TRAD_RS07040 ^@ http://purl.uniprot.org/uniprot/D7CX32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS09040 ^@ http://purl.uniprot.org/uniprot/D7CQF8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/649638:TRAD_RS01370 ^@ http://purl.uniprot.org/uniprot/D7CR07 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/649638:TRAD_RS08620 ^@ http://purl.uniprot.org/uniprot/D7CQ73 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/649638:TRAD_RS13020 ^@ http://purl.uniprot.org/uniprot/D7CUD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS08725 ^@ http://purl.uniprot.org/uniprot/D7CQ93 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/649638:TRAD_RS10770 ^@ http://purl.uniprot.org/uniprot/D7CRV3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS08115 ^@ http://purl.uniprot.org/uniprot/D7CYB7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/649638:TRAD_RS09245 ^@ http://purl.uniprot.org/uniprot/D7CQJ9 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/649638:TRAD_RS01050 ^@ http://purl.uniprot.org/uniprot/D7CXY6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS14495 ^@ http://purl.uniprot.org/uniprot/D7CVV1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS09840 ^@ http://purl.uniprot.org/uniprot/D7CQW7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/649638:TRAD_RS06945 ^@ http://purl.uniprot.org/uniprot/D7CX13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/649638:TRAD_RS11255 ^@ http://purl.uniprot.org/uniprot/D7CSF3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS05850 ^@ http://purl.uniprot.org/uniprot/D7CW39 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/649638:TRAD_RS04605 ^@ http://purl.uniprot.org/uniprot/D7CUR3 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/649638:TRAD_RS00585 ^@ http://purl.uniprot.org/uniprot/D7CXD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/649638:TRAD_RS12320 ^@ http://purl.uniprot.org/uniprot/D7CTN6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/649638:TRAD_RS02985 ^@ http://purl.uniprot.org/uniprot/D7CSW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/649638:TRAD_RS13670 ^@ http://purl.uniprot.org/uniprot/D7CV16 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/649638:TRAD_RS12045 ^@ http://purl.uniprot.org/uniprot/D7CT65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/649638:TRAD_RS10015 ^@ http://purl.uniprot.org/uniprot/D7CR01 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/649638:TRAD_RS10455 ^@ http://purl.uniprot.org/uniprot/D7CRD3 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/649638:TRAD_RS07630 ^@ http://purl.uniprot.org/uniprot/D7CXQ8 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/649638:TRAD_RS03895 ^@ http://purl.uniprot.org/uniprot/D7CU19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS04130 ^@ http://purl.uniprot.org/uniprot/D7CU66 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/649638:TRAD_RS11545 ^@ http://purl.uniprot.org/uniprot/D7CSL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AlgX family.|||Periplasm http://togogenome.org/gene/649638:TRAD_RS05430 ^@ http://purl.uniprot.org/uniprot/D7CVI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS14030 ^@ http://purl.uniprot.org/uniprot/D7CVK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/649638:TRAD_RS09915 ^@ http://purl.uniprot.org/uniprot/D7CQY2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/649638:TRAD_RS09250 ^@ http://purl.uniprot.org/uniprot/D7CQK0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/649638:TRAD_RS05310 ^@ http://purl.uniprot.org/uniprot/D7CVG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/649638:TRAD_RS00930 ^@ http://purl.uniprot.org/uniprot/D7CXW2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/649638:TRAD_RS11940 ^@ http://purl.uniprot.org/uniprot/D7CT43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS07200 ^@ http://purl.uniprot.org/uniprot/D7CXH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/649638:TRAD_RS01750 ^@ http://purl.uniprot.org/uniprot/D7CRJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS13970 ^@ http://purl.uniprot.org/uniprot/D7CV74 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/649638:TRAD_RS00320 ^@ http://purl.uniprot.org/uniprot/D7CX82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS00625 ^@ http://purl.uniprot.org/uniprot/D7CXD9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/649638:TRAD_RS11465 ^@ http://purl.uniprot.org/uniprot/D7CSJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/649638:TRAD_RS05405 ^@ http://purl.uniprot.org/uniprot/D7CVI3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/649638:TRAD_RS04500 ^@ http://purl.uniprot.org/uniprot/D7CUP1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/649638:TRAD_RS00710 ^@ http://purl.uniprot.org/uniprot/D7CXF5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS03595 ^@ http://purl.uniprot.org/uniprot/D7CTJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/649638:TRAD_RS07565 ^@ http://purl.uniprot.org/uniprot/D7CXP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/649638:TRAD_RS13455 ^@ http://purl.uniprot.org/uniprot/D7CUX3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/649638:TRAD_RS05560 ^@ http://purl.uniprot.org/uniprot/D7CVY0 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/649638:TRAD_RS02085 ^@ http://purl.uniprot.org/uniprot/D7CRR0 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/649638:TRAD_RS04260 ^@ http://purl.uniprot.org/uniprot/D7CU92 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/649638:TRAD_RS09735 ^@ http://purl.uniprot.org/uniprot/D7CQU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS10290 ^@ http://purl.uniprot.org/uniprot/D7CRA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/649638:TRAD_RS00495 ^@ http://purl.uniprot.org/uniprot/D7CXB3 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/649638:TRAD_RS01865 ^@ http://purl.uniprot.org/uniprot/D7CRL6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/649638:TRAD_RS08750 ^@ http://purl.uniprot.org/uniprot/D7CQ98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/649638:TRAD_RS09530 ^@ http://purl.uniprot.org/uniprot/D7CQQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/649638:TRAD_RS11390 ^@ http://purl.uniprot.org/uniprot/D7CSH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS16550 ^@ http://purl.uniprot.org/uniprot/D7CTU8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/649638:TRAD_RS07245 ^@ http://purl.uniprot.org/uniprot/D7CXI2 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/649638:TRAD_RS14050 ^@ http://purl.uniprot.org/uniprot/D7CVK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/649638:TRAD_RS07460 ^@ http://purl.uniprot.org/uniprot/D7CXM4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.|||Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homotetramer. http://togogenome.org/gene/649638:TRAD_RS13485 ^@ http://purl.uniprot.org/uniprot/D7CUX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/649638:TRAD_RS00760 ^@ http://purl.uniprot.org/uniprot/D7CXG5 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/649638:TRAD_RS02400 ^@ http://purl.uniprot.org/uniprot/D7CS79 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/649638:TRAD_RS06385 ^@ http://purl.uniprot.org/uniprot/D7CWK8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/649638:TRAD_RS06960 ^@ http://purl.uniprot.org/uniprot/D7CX16 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/649638:TRAD_RS07950 ^@ http://purl.uniprot.org/uniprot/D7CY85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/649638:TRAD_RS11595 ^@ http://purl.uniprot.org/uniprot/D7CSM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/649638:TRAD_RS14825 ^@ http://purl.uniprot.org/uniprot/D7CWC7 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster.