http://togogenome.org/gene/7719:LOC100182180 ^@ http://purl.uniprot.org/uniprot/F6YG66 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/7719:foxp ^@ http://purl.uniprot.org/uniprot/Q4H3H6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185660 ^@ http://purl.uniprot.org/uniprot/F6Y1S7 ^@ Cofactor ^@ Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain. http://togogenome.org/gene/7719:LOC100177734 ^@ http://purl.uniprot.org/uniprot/H2XY02 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7719:LOC100178653 ^@ http://purl.uniprot.org/uniprot/F6S277 ^@ Similarity ^@ Belongs to the GST superfamily. Mu family. http://togogenome.org/gene/7719:LOC100185334 ^@ http://purl.uniprot.org/uniprot/F6PZT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG7 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:fgfl ^@ http://purl.uniprot.org/uniprot/Q8I6J2 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7719:LOC100175191 ^@ http://purl.uniprot.org/uniprot/F7AB27 ^@ Similarity ^@ Belongs to the DENND11 family. http://togogenome.org/gene/7719:LOC100178052 ^@ http://purl.uniprot.org/uniprot/F6Y0G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100175852 ^@ http://purl.uniprot.org/uniprot/H2XZ61 ^@ Similarity ^@ Belongs to the MS4A family. http://togogenome.org/gene/7719:LOC100180632 ^@ http://purl.uniprot.org/uniprot/F6ZZJ8 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/7719:LOC100180472 ^@ http://purl.uniprot.org/uniprot/F6VUE0 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/7719:zf(c2h2)-84 ^@ http://purl.uniprot.org/uniprot/Q1RLE7 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/7719:hb3 ^@ http://purl.uniprot.org/uniprot/Q70T62 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7719:LOC100175495 ^@ http://purl.uniprot.org/uniprot/F6Z010 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/7719:hnf4 ^@ http://purl.uniprot.org/uniprot/Q4H3D4|||http://purl.uniprot.org/uniprot/Q4H3D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100176946 ^@ http://purl.uniprot.org/uniprot/F7BH30|||http://purl.uniprot.org/uniprot/Q9BKE8 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/7719:LOC100176990 ^@ http://purl.uniprot.org/uniprot/H2XRR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100178236 ^@ http://purl.uniprot.org/uniprot/F6T385 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:LOC100176873 ^@ http://purl.uniprot.org/uniprot/H2XXZ8 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:eph3 ^@ http://purl.uniprot.org/uniprot/Q4H3M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100179039 ^@ http://purl.uniprot.org/uniprot/H2XU29 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/7719:LOC100177698 ^@ http://purl.uniprot.org/uniprot/H2Y123 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/7719:ephrinb ^@ http://purl.uniprot.org/uniprot/Q4H3L8 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:dusp1.2.4.5 ^@ http://purl.uniprot.org/uniprot/Q4H3P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Nucleus http://togogenome.org/gene/7719:ptp ^@ http://purl.uniprot.org/uniprot/Q9NDP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.|||cytoskeleton http://togogenome.org/gene/7719:LOC100187083 ^@ http://purl.uniprot.org/uniprot/F6XDI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7719:LOC100178272 ^@ http://purl.uniprot.org/uniprot/F6PK60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MESD family.|||Endoplasmic reticulum http://togogenome.org/gene/7719:ciaxp83.9 ^@ http://purl.uniprot.org/uniprot/Q8T880 ^@ Similarity ^@ Belongs to the DNAI7 family. http://togogenome.org/gene/7719:LOC100179166 ^@ http://purl.uniprot.org/uniprot/A0A1W2W1I3 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/7719:LOC100184986 ^@ http://purl.uniprot.org/uniprot/H2XTZ1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/7719:LOC100184076 ^@ http://purl.uniprot.org/uniprot/F6PLF9 ^@ Function|||Similarity ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.|||Belongs to the glycosyl hydrolase 29 family. http://togogenome.org/gene/7719:ets/pointed1 ^@ http://purl.uniprot.org/uniprot/H2XK31|||http://purl.uniprot.org/uniprot/Q4H3K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC100186210 ^@ http://purl.uniprot.org/uniprot/F6PV21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDC1 family.|||Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.|||Membrane|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/7719:cdx ^@ http://purl.uniprot.org/uniprot/Q4H3T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100184992 ^@ http://purl.uniprot.org/uniprot/F7AWW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR2 family.|||Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.|||Membrane http://togogenome.org/gene/7719:LOC100185178 ^@ http://purl.uniprot.org/uniprot/Q6R4N6 ^@ Subcellular Location Annotation ^@ Membrane|||dendrite http://togogenome.org/gene/7719:LOC778662 ^@ http://purl.uniprot.org/uniprot/Q4H397 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7719:LOC100185384 ^@ http://purl.uniprot.org/uniprot/A0A1W2WKI9 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus http://togogenome.org/gene/7719:LOC100177011 ^@ http://purl.uniprot.org/uniprot/F6XCN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GAMAD family.|||Lysosome membrane http://togogenome.org/gene/7719:LOC100182431 ^@ http://purl.uniprot.org/uniprot/F6XZL0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/7719:LOC100175224 ^@ http://purl.uniprot.org/uniprot/H2XRU5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100175935 ^@ http://purl.uniprot.org/uniprot/F6U019 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/7719:LOC100185032 ^@ http://purl.uniprot.org/uniprot/F7A0S5 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/7719:LOC100187058 ^@ http://purl.uniprot.org/uniprot/F6VSM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/7719:ephe ^@ http://purl.uniprot.org/uniprot/Q4H3M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100180661 ^@ http://purl.uniprot.org/uniprot/F6WQS5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lunapark family.|||Endoplasmic reticulum membrane|||Plays a role in determining ER morphology.|||The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation. http://togogenome.org/gene/7719:LOC100184890 ^@ http://purl.uniprot.org/uniprot/F6WES8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:nachr ^@ http://purl.uniprot.org/uniprot/E7FIY7|||http://purl.uniprot.org/uniprot/E7FIZ3|||http://purl.uniprot.org/uniprot/E7FIZ4|||http://purl.uniprot.org/uniprot/E7FIZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7719:LOC100178742 ^@ http://purl.uniprot.org/uniprot/H2XMS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:foxm ^@ http://purl.uniprot.org/uniprot/Q4H3I0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100180716 ^@ http://purl.uniprot.org/uniprot/A0A1W2WHY7 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL31 family.|||Component of the large ribosomal subunit. http://togogenome.org/gene/7719:LOC100179198 ^@ http://purl.uniprot.org/uniprot/H2XK43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/7719:zf(c2h2)-126 ^@ http://purl.uniprot.org/uniprot/Q1RPW8 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/7719:LOC100179695 ^@ http://purl.uniprot.org/uniprot/F6ZNP4 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/7719:LOC100176157 ^@ http://purl.uniprot.org/uniprot/F6XB39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7719:LOC100169893 ^@ http://purl.uniprot.org/uniprot/Q0GBX3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100184516 ^@ http://purl.uniprot.org/uniprot/F6XEV8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/7719:LOC100177778 ^@ http://purl.uniprot.org/uniprot/F6WM99 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.|||Nucleus http://togogenome.org/gene/7719:LOC100177903 ^@ http://purl.uniprot.org/uniprot/H2XSW8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7719:LOC100186389 ^@ http://purl.uniprot.org/uniprot/A0A1W3JVH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TMEM214 family.|||Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.|||Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100178916 ^@ http://purl.uniprot.org/uniprot/H2XTI5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7719:leprecan ^@ http://purl.uniprot.org/uniprot/Q9NDP6 ^@ Similarity ^@ Belongs to the leprecan family. http://togogenome.org/gene/7719:LOC100177468 ^@ http://purl.uniprot.org/uniprot/F6Y3M3 ^@ Similarity ^@ Belongs to the ACTMAP family. http://togogenome.org/gene/7719:LOC104265895 ^@ http://purl.uniprot.org/uniprot/F7AW07 ^@ Similarity|||Subunit ^@ Belongs to the archease family.|||Component of the tRNA-splicing ligase complex. http://togogenome.org/gene/7719:LOC100178921 ^@ http://purl.uniprot.org/uniprot/F6TPB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM263 family.|||Membrane http://togogenome.org/gene/7719:LOC100183239 ^@ http://purl.uniprot.org/uniprot/F6Z423 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. http://togogenome.org/gene/7719:not2 ^@ http://purl.uniprot.org/uniprot/Q9NDQ6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7719:LOC100181322 ^@ http://purl.uniprot.org/uniprot/F6VM90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:vachtp ^@ http://purl.uniprot.org/uniprot/Q8STE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:rhamm ^@ http://purl.uniprot.org/uniprot/F6XWF2 ^@ Subcellular Location Annotation ^@ spindle http://togogenome.org/gene/7719:LOC100183442 ^@ http://purl.uniprot.org/uniprot/F6V5I4 ^@ Similarity ^@ Belongs to the NPR2 family. http://togogenome.org/gene/7719:LOC100182480 ^@ http://purl.uniprot.org/uniprot/H2XVJ4 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/7719:LOC100186879 ^@ http://purl.uniprot.org/uniprot/H2XQC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 28 family.|||Nucleus http://togogenome.org/gene/7719:LOC100178933 ^@ http://purl.uniprot.org/uniprot/F6PHD5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/7719:LOC100175647 ^@ http://purl.uniprot.org/uniprot/F6PQL4 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/7719:LOC100184784 ^@ http://purl.uniprot.org/uniprot/F6PK93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7719:LOC100176054 ^@ http://purl.uniprot.org/uniprot/F6YA95 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/7719:LOC100178347 ^@ http://purl.uniprot.org/uniprot/F6TIH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100175197 ^@ http://purl.uniprot.org/uniprot/F6TE87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ashwin family.|||Nucleus http://togogenome.org/gene/7719:LOC100186457 ^@ http://purl.uniprot.org/uniprot/H2XXZ7 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/7719:LOC100184402 ^@ http://purl.uniprot.org/uniprot/A0A1W2WCL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100184455 ^@ http://purl.uniprot.org/uniprot/F7B5Z4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/7719:LOC100178755 ^@ http://purl.uniprot.org/uniprot/F6QAA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase CarF family.|||Membrane http://togogenome.org/gene/7719:LOC100185377 ^@ http://purl.uniprot.org/uniprot/F6U9J6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC445729 ^@ http://purl.uniprot.org/uniprot/Q6XZ10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Membrane http://togogenome.org/gene/7719:LOC100186251 ^@ http://purl.uniprot.org/uniprot/F6XVZ5 ^@ Function|||Similarity ^@ Belongs to the calponin family.|||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. http://togogenome.org/gene/7719:ipf1 ^@ http://purl.uniprot.org/uniprot/Q9GP86 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:vdr-a ^@ http://purl.uniprot.org/uniprot/Q4H2N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100178879 ^@ http://purl.uniprot.org/uniprot/F7AMB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/7719:LOC100175648 ^@ http://purl.uniprot.org/uniprot/F6QZE9 ^@ Function|||Similarity ^@ Belongs to the TSR2 family.|||May be involved in 20S pre-rRNA processing. http://togogenome.org/gene/7719:Ci-CT-R ^@ http://purl.uniprot.org/uniprot/D2KVR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100186249 ^@ http://purl.uniprot.org/uniprot/A0A1W2WI04 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/7719:thymosin%20beta ^@ http://purl.uniprot.org/uniprot/Q86SC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||cytoskeleton http://togogenome.org/gene/7719:LOC100177728 ^@ http://purl.uniprot.org/uniprot/H2XM23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:c3-1 ^@ http://purl.uniprot.org/uniprot/Q8WPD8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7719:LOC100184638 ^@ http://purl.uniprot.org/uniprot/F6X3V2 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/7719:LOC100175406 ^@ http://purl.uniprot.org/uniprot/H2XR11 ^@ Similarity ^@ Belongs to the SKA1 family. http://togogenome.org/gene/7719:cifrz ^@ http://purl.uniprot.org/uniprot/Q9NL45 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100179159 ^@ http://purl.uniprot.org/uniprot/F6R4Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RITA family.|||Cytoplasm|||Interacts with RBPJ/RBPSUH.|||Nucleus|||Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. http://togogenome.org/gene/7719:LOC100180619 ^@ http://purl.uniprot.org/uniprot/F6X211 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/7719:LOC100186310 ^@ http://purl.uniprot.org/uniprot/F6ZL23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the jagunal family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:spi/pu.1 ^@ http://purl.uniprot.org/uniprot/Q4H2R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC100175182 ^@ http://purl.uniprot.org/uniprot/H2XS20 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/7719:LOC778790 ^@ http://purl.uniprot.org/uniprot/Q4H2N2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100175975 ^@ http://purl.uniprot.org/uniprot/F6R554 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100187188 ^@ http://purl.uniprot.org/uniprot/F6TN66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:LOC100183772 ^@ http://purl.uniprot.org/uniprot/F6PUC9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100178780 ^@ http://purl.uniprot.org/uniprot/F6ZPP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ATPase subunit F6 family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.|||Mitochondrion http://togogenome.org/gene/7719:LOC100178586 ^@ http://purl.uniprot.org/uniprot/A0A1W3JW59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100175998 ^@ http://purl.uniprot.org/uniprot/H2Y2S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||cytoskeleton http://togogenome.org/gene/7719:LOC100176354 ^@ http://purl.uniprot.org/uniprot/F6TTZ5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cytoplasm http://togogenome.org/gene/7719:LOC100182592 ^@ http://purl.uniprot.org/uniprot/H2XM94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/7719:lag1-like3 ^@ http://purl.uniprot.org/uniprot/Q4H395 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7719:not3 ^@ http://purl.uniprot.org/uniprot/Q9NDQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC104265377 ^@ http://purl.uniprot.org/uniprot/F6RU13 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/7719:LOC100182530 ^@ http://purl.uniprot.org/uniprot/F6ZTZ7 ^@ Similarity|||Subunit ^@ Belongs to the group II decarboxylase family.|||Homodimer. http://togogenome.org/gene/7719:LOC100187361 ^@ http://purl.uniprot.org/uniprot/F6SJU9 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/7719:LOC100180256 ^@ http://purl.uniprot.org/uniprot/F7A355 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/7719:LOC100182198 ^@ http://purl.uniprot.org/uniprot/F6YIH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAUS3 family.|||spindle http://togogenome.org/gene/7719:cytb561 ^@ http://purl.uniprot.org/uniprot/Q8MYB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100182764 ^@ http://purl.uniprot.org/uniprot/F6PMD1 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7719:LOC100187100 ^@ http://purl.uniprot.org/uniprot/F6R107 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/7719:foxE ^@ http://purl.uniprot.org/uniprot/Q70VZ3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:tr2/4 ^@ http://purl.uniprot.org/uniprot/Q1RPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7719:LOC100179627 ^@ http://purl.uniprot.org/uniprot/F6UYE6 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7719:LOC100178567 ^@ http://purl.uniprot.org/uniprot/F6SM47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/7719:LOC778717 ^@ http://purl.uniprot.org/uniprot/Q4H315 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100181439 ^@ http://purl.uniprot.org/uniprot/F6RWY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LZTFL1 family.|||Cytoplasm|||Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.|||Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking. http://togogenome.org/gene/7719:LOC100177099 ^@ http://purl.uniprot.org/uniprot/F6QKB5 ^@ Similarity ^@ Belongs to the NRDE2 family. http://togogenome.org/gene/7719:LOC100183345 ^@ http://purl.uniprot.org/uniprot/Q659T9 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:LOC445732 ^@ http://purl.uniprot.org/uniprot/Q6XDT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/7719:LOC100181337 ^@ http://purl.uniprot.org/uniprot/F7ANT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100184729 ^@ http://purl.uniprot.org/uniprot/F7AD34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMP-30/CGR1 family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100181334 ^@ http://purl.uniprot.org/uniprot/F6ZIC6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100181042 ^@ http://purl.uniprot.org/uniprot/H2XWJ8 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/7719:foxi-b ^@ http://purl.uniprot.org/uniprot/Q4H3I5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100183973 ^@ http://purl.uniprot.org/uniprot/F6SST4 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/7719:zf(cchc)-12 ^@ http://purl.uniprot.org/uniprot/Q1RLD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/7719:LOC100184867 ^@ http://purl.uniprot.org/uniprot/H2XTW7 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/7719:LOC100176459 ^@ http://purl.uniprot.org/uniprot/F6REI3 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/7719:LOC100176070 ^@ http://purl.uniprot.org/uniprot/F6Y1Z7 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/7719:kcnq4/5 ^@ http://purl.uniprot.org/uniprot/C0JSV8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100176919 ^@ http://purl.uniprot.org/uniprot/F6PZ24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7719:LOC100175572 ^@ http://purl.uniprot.org/uniprot/F6VGH4 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7719:LOC100182514 ^@ http://purl.uniprot.org/uniprot/H2XWZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||PML body http://togogenome.org/gene/7719:foxL ^@ http://purl.uniprot.org/uniprot/Q70VZ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178367 ^@ http://purl.uniprot.org/uniprot/H2XTC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/7719:zf(c3h)-12 ^@ http://purl.uniprot.org/uniprot/Q1RPY1 ^@ Similarity ^@ Belongs to the SLT11 family. http://togogenome.org/gene/7719:LOC100185129 ^@ http://purl.uniprot.org/uniprot/F6S855 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:irx-c ^@ http://purl.uniprot.org/uniprot/Q4H3A6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100182035 ^@ http://purl.uniprot.org/uniprot/F6TBA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN8 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100177476 ^@ http://purl.uniprot.org/uniprot/F6ZRB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1A family.|||Nucleus http://togogenome.org/gene/7719:LOC100186602 ^@ http://purl.uniprot.org/uniprot/F6RC25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:tgfbr-ib ^@ http://purl.uniprot.org/uniprot/Q4H2Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/7719:LOC100186347 ^@ http://purl.uniprot.org/uniprot/F6TEA0 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/7719:LOC100187147 ^@ http://purl.uniprot.org/uniprot/F7ARN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SDHAF2 family.|||Interacts with the flavoprotein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. http://togogenome.org/gene/7719:asak ^@ http://purl.uniprot.org/uniprot/F7BBN1|||http://purl.uniprot.org/uniprot/Q9NDP8 ^@ Similarity ^@ In the C-terminal section; belongs to the sulfate adenylyltransferase family.|||In the N-terminal section; belongs to the APS kinase family. http://togogenome.org/gene/7719:LOC100176983 ^@ http://purl.uniprot.org/uniprot/F6ZST9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:xt ^@ http://purl.uniprot.org/uniprot/Q5QQ55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 14 family. XylT subfamily.|||Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane http://togogenome.org/gene/7719:LOC100187335 ^@ http://purl.uniprot.org/uniprot/F7AA18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cystinosin family.|||Membrane http://togogenome.org/gene/7719:LOC100182304 ^@ http://purl.uniprot.org/uniprot/F7AF59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/7719:LOC100177985 ^@ http://purl.uniprot.org/uniprot/H2XWE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7719:LOC100178248 ^@ http://purl.uniprot.org/uniprot/F6QEE3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100186203 ^@ http://purl.uniprot.org/uniprot/F7AYB9 ^@ Function|||Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. http://togogenome.org/gene/7719:LOC100178741 ^@ http://purl.uniprot.org/uniprot/F6Q9B5 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/7719:capza ^@ http://purl.uniprot.org/uniprot/F6W9C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/7719:LOC100177329 ^@ http://purl.uniprot.org/uniprot/F6X9G1 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/7719:LOC100185510 ^@ http://purl.uniprot.org/uniprot/A0A1W2WET0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7719:LOC100178575 ^@ http://purl.uniprot.org/uniprot/Q4H2T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC108949278 ^@ http://purl.uniprot.org/uniprot/A0A1W2WCG1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/7719:LOC100177970 ^@ http://purl.uniprot.org/uniprot/F6R683 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B4 family.|||Nucleus http://togogenome.org/gene/7719:LOC100177909 ^@ http://purl.uniprot.org/uniprot/F6UTS4 ^@ Similarity ^@ Belongs to the HscB family. http://togogenome.org/gene/7719:ona14 ^@ http://purl.uniprot.org/uniprot/Q6A1F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:cnot7/8 ^@ http://purl.uniprot.org/uniprot/Q4H3S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/7719:LOC100182206 ^@ http://purl.uniprot.org/uniprot/F6SM68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/7719:LOC100186495 ^@ http://purl.uniprot.org/uniprot/F6R8G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:lmx ^@ http://purl.uniprot.org/uniprot/Q4H389 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100187432 ^@ http://purl.uniprot.org/uniprot/F7AUH4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/7719:LOC100180671 ^@ http://purl.uniprot.org/uniprot/H2XMT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100177878 ^@ http://purl.uniprot.org/uniprot/F6S8N1 ^@ Similarity ^@ Belongs to the CCM2 family. http://togogenome.org/gene/7719:LOC100177419 ^@ http://purl.uniprot.org/uniprot/F6YX42 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/7719:LOC100186730 ^@ http://purl.uniprot.org/uniprot/A0A1W2WEW7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/7719:LOC100180846 ^@ http://purl.uniprot.org/uniprot/F6R4I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100176811 ^@ http://purl.uniprot.org/uniprot/F6XM37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7719:rl32 ^@ http://purl.uniprot.org/uniprot/Q8I7D3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/7719:ephrina-b ^@ http://purl.uniprot.org/uniprot/Q4H3M1 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100184518 ^@ http://purl.uniprot.org/uniprot/H2XPA7 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/7719:LOC100181779 ^@ http://purl.uniprot.org/uniprot/Q69HN2 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/7719:pax1/9 ^@ http://purl.uniprot.org/uniprot/O96090|||http://purl.uniprot.org/uniprot/Q4H2Z4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100180182 ^@ http://purl.uniprot.org/uniprot/F6Z2T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/7719:LOC100177160 ^@ http://purl.uniprot.org/uniprot/F7BI48 ^@ Similarity ^@ Belongs to the MIX23 family. http://togogenome.org/gene/7719:fgf8/17/18 ^@ http://purl.uniprot.org/uniprot/Q8I6J5 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7719:ets/pointed2 ^@ http://purl.uniprot.org/uniprot/Q4H3K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:mech2 ^@ http://purl.uniprot.org/uniprot/Q68A30 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100185662 ^@ http://purl.uniprot.org/uniprot/F6XJ08 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/7719:LOC100180912 ^@ http://purl.uniprot.org/uniprot/F6Y4F7 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7719:tolloid ^@ http://purl.uniprot.org/uniprot/Q4H2P2 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100176786 ^@ http://purl.uniprot.org/uniprot/A0A1W5B8I0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7719:LOC100178363 ^@ http://purl.uniprot.org/uniprot/A0A1W3JIP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the borealin family.|||centromere http://togogenome.org/gene/7719:su(h) ^@ http://purl.uniprot.org/uniprot/O76808|||http://purl.uniprot.org/uniprot/Q4H2Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Su(H) family.|||Interacts with activated Notch proteins.|||Nucleus|||Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation. http://togogenome.org/gene/7719:LOC100185985 ^@ http://purl.uniprot.org/uniprot/A0A1W5BGB6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:gpx7 ^@ http://purl.uniprot.org/uniprot/F6RM35 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/7719:LOC100187496 ^@ http://purl.uniprot.org/uniprot/F6U6L5 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/7719:LOC100183027 ^@ http://purl.uniprot.org/uniprot/F6Z1E3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/7719:LOC100175820 ^@ http://purl.uniprot.org/uniprot/F6PST3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/7719:en ^@ http://purl.uniprot.org/uniprot/Q8IAC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the engrailed homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100176748 ^@ http://purl.uniprot.org/uniprot/F6RHG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.|||Belongs to the VPS29 family.|||Endosome membrane http://togogenome.org/gene/7719:LOC100185878 ^@ http://purl.uniprot.org/uniprot/A0A1W2WPI0 ^@ Similarity ^@ Belongs to the SMAP family. http://togogenome.org/gene/7719:foxi-a ^@ http://purl.uniprot.org/uniprot/Q4H3I6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:bco ^@ http://purl.uniprot.org/uniprot/Q2PE72 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/7719:LOC101242487 ^@ http://purl.uniprot.org/uniprot/F6WC51 ^@ Similarity ^@ Belongs to the SMIM7 family. http://togogenome.org/gene/7719:LOC100185650 ^@ http://purl.uniprot.org/uniprot/F6ZWW6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/7719:LOC100187137 ^@ http://purl.uniprot.org/uniprot/F6RS75 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in spermatogenesis.|||Nucleus http://togogenome.org/gene/7719:LOC100185679 ^@ http://purl.uniprot.org/uniprot/F7B7V5 ^@ Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked. http://togogenome.org/gene/7719:LOC100181205 ^@ http://purl.uniprot.org/uniprot/F6RQZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Endoplasmic reticulum membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/7719:LOC100178020 ^@ http://purl.uniprot.org/uniprot/F6T0X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS5 family.|||Membrane|||centriolar satellite|||cilium membrane http://togogenome.org/gene/7719:LOC100187030 ^@ http://purl.uniprot.org/uniprot/H2XVV1 ^@ Similarity ^@ Belongs to the UQCRH/QCR6 family. http://togogenome.org/gene/7719:LOC100183635 ^@ http://purl.uniprot.org/uniprot/F6W8U8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7719:LOC100179962 ^@ http://purl.uniprot.org/uniprot/F6SKS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FRG1 family.|||Cajal body|||nucleolus http://togogenome.org/gene/7719:foxd-a/b ^@ http://purl.uniprot.org/uniprot/Q4H3J2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:ciic3 ^@ http://purl.uniprot.org/uniprot/Q95YJ5 ^@ Domain|||Function|||Similarity|||Tissue Specificity ^@ Contains 3 inactive NDK domains that each lack the active His residue, suggesting that they have no NDP kinase activity.|||In the C-terminal section; belongs to the NDK family.|||May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity).|||Testis-specific. http://togogenome.org/gene/7719:ci-ndk/dm44 ^@ http://purl.uniprot.org/uniprot/C4B8X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||cilium axoneme http://togogenome.org/gene/7719:LOC100177511 ^@ http://purl.uniprot.org/uniprot/F7B0X0 ^@ Function|||Similarity ^@ Belongs to the QNG1 protein family.|||Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly. http://togogenome.org/gene/7719:LOC100179621 ^@ http://purl.uniprot.org/uniprot/A0A1W5BRK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/7719:LOC104265547 ^@ http://purl.uniprot.org/uniprot/H2XM88 ^@ Similarity ^@ Belongs to the DDA1 family. http://togogenome.org/gene/7719:LOC100184767 ^@ http://purl.uniprot.org/uniprot/F6Z6Y7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.|||In the N-terminal section; belongs to the GART family. http://togogenome.org/gene/7719:LOC100178764 ^@ http://purl.uniprot.org/uniprot/E0XJK1 ^@ Similarity ^@ Belongs to the thrombospondin family. http://togogenome.org/gene/7719:r35a ^@ http://purl.uniprot.org/uniprot/Q8I7D7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/7719:ci-mytf ^@ http://purl.uniprot.org/uniprot/Q1RLF9|||http://purl.uniprot.org/uniprot/Q4H360 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:b4galt ^@ http://purl.uniprot.org/uniprot/Q9NDP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Catalyses the transfer of galactose onto proteins or lipids.|||Membrane http://togogenome.org/gene/7719:foxk ^@ http://purl.uniprot.org/uniprot/Q4H3I2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100175875 ^@ http://purl.uniprot.org/uniprot/F7AEB8 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/7719:LOC100181226 ^@ http://purl.uniprot.org/uniprot/H2XS22 ^@ Similarity ^@ Belongs to the UPF0524 family. http://togogenome.org/gene/7719:uglcat2l ^@ http://purl.uniprot.org/uniprot/H2XX32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100179957 ^@ http://purl.uniprot.org/uniprot/F6V0K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:erf2 ^@ http://purl.uniprot.org/uniprot/Q4H3L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC778671 ^@ http://purl.uniprot.org/uniprot/Q4H384 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100186699 ^@ http://purl.uniprot.org/uniprot/H2XWL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100185362 ^@ http://purl.uniprot.org/uniprot/F6Y1B6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100182436 ^@ http://purl.uniprot.org/uniprot/F6U1G1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/7719:LOC100183021 ^@ http://purl.uniprot.org/uniprot/F6VZ84 ^@ Cofactor|||Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/7719:LOC100180595 ^@ http://purl.uniprot.org/uniprot/H2XL09 ^@ Function|||Similarity ^@ Belongs to the ODR-4 family.|||May play a role in the trafficking of a subset of G-protein coupled receptors. http://togogenome.org/gene/7719:gla3 ^@ http://purl.uniprot.org/uniprot/Q008W2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100186965 ^@ http://purl.uniprot.org/uniprot/F6RN78 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100182272 ^@ http://purl.uniprot.org/uniprot/F6UH59 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/7719:LOC100185031 ^@ http://purl.uniprot.org/uniprot/F7AKV1 ^@ Similarity ^@ Belongs to the villin/gelsolin family. http://togogenome.org/gene/7719:LOC101242287 ^@ http://purl.uniprot.org/uniprot/F6W1F7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/7719:LOC100180692 ^@ http://purl.uniprot.org/uniprot/F6XE85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.|||Belongs to the HIBADH-related family. NP60 subfamily.|||Chromosome http://togogenome.org/gene/7719:LOC100181085 ^@ http://purl.uniprot.org/uniprot/F7BMP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7719:LOC100181271 ^@ http://purl.uniprot.org/uniprot/H2XUJ2 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/7719:erm/er81 ^@ http://purl.uniprot.org/uniprot/Q4H3L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC100175025 ^@ http://purl.uniprot.org/uniprot/F6TQG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.|||Cytoplasm|||Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. http://togogenome.org/gene/7719:LOC100184077 ^@ http://purl.uniprot.org/uniprot/H2XSJ8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178661 ^@ http://purl.uniprot.org/uniprot/F6TLK5 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:LOC100180887 ^@ http://purl.uniprot.org/uniprot/F6Y089 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Cytoplasm|||Homodimer.|||Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. http://togogenome.org/gene/7719:LOC100182785 ^@ http://purl.uniprot.org/uniprot/F6WNP2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100187279 ^@ http://purl.uniprot.org/uniprot/H2XQX6 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. http://togogenome.org/gene/7719:LOC100183224 ^@ http://purl.uniprot.org/uniprot/H2XLJ3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7719:ona1 ^@ http://purl.uniprot.org/uniprot/Q86NA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:LOC100186846 ^@ http://purl.uniprot.org/uniprot/F6ZB45 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179384 ^@ http://purl.uniprot.org/uniprot/A0A1W2WHS9 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/7719:LOC100184165 ^@ http://purl.uniprot.org/uniprot/H2XVN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB4 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.|||Nucleus|||Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7. http://togogenome.org/gene/7719:LOC100178827 ^@ http://purl.uniprot.org/uniprot/H2XT41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7719:LOC100183394 ^@ http://purl.uniprot.org/uniprot/F7BC32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/7719:LOC100184460 ^@ http://purl.uniprot.org/uniprot/F6V1C0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit.|||Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. http://togogenome.org/gene/7719:tcf/lef ^@ http://purl.uniprot.org/uniprot/Q4H2Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/7719:LOC100176371 ^@ http://purl.uniprot.org/uniprot/A0A1W5BHV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/7719:LOC100180956 ^@ http://purl.uniprot.org/uniprot/F6Z750 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100181036 ^@ http://purl.uniprot.org/uniprot/H2Y3F1 ^@ Similarity|||Subunit ^@ Belongs to the DapA family.|||Homotetramer. http://togogenome.org/gene/7719:LOC100180313 ^@ http://purl.uniprot.org/uniprot/H2XKF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/7719:LOC100179526 ^@ http://purl.uniprot.org/uniprot/F6QEH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7719:prd-b ^@ http://purl.uniprot.org/uniprot/Q4H2X2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:stat-b ^@ http://purl.uniprot.org/uniprot/Q4H2R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcription factor STAT family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100177393 ^@ http://purl.uniprot.org/uniprot/F6Q9P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity.|||Monomer and homodimer.|||Nucleus http://togogenome.org/gene/7719:LOC104266887 ^@ http://purl.uniprot.org/uniprot/H2Y0Q2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100187034 ^@ http://purl.uniprot.org/uniprot/F6WH15 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/7719:pou-like ^@ http://purl.uniprot.org/uniprot/Q4H2X7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100184140 ^@ http://purl.uniprot.org/uniprot/F6SKV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/7719:rhysin2/deltex3-c ^@ http://purl.uniprot.org/uniprot/Q4H2V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Deltex family.|||Cytoplasm http://togogenome.org/gene/7719:LOC101242392 ^@ http://purl.uniprot.org/uniprot/F6PN13 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/7719:LOC100185070 ^@ http://purl.uniprot.org/uniprot/H2XVT8 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/7719:cibeta-catenin ^@ http://purl.uniprot.org/uniprot/Q4H3U7 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/7719:LOC100180875 ^@ http://purl.uniprot.org/uniprot/F6QQM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC104265369 ^@ http://purl.uniprot.org/uniprot/F6YGN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/7719:LOC100180439 ^@ http://purl.uniprot.org/uniprot/A0A1W5BDE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/7719:LOC100177517 ^@ http://purl.uniprot.org/uniprot/F6XZJ5 ^@ Function|||Subcellular Location Annotation ^@ May play a role during embryogenesis.|||kinetochore http://togogenome.org/gene/7719:LOC100177596 ^@ http://purl.uniprot.org/uniprot/F6TMJ9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/7719:ache ^@ http://purl.uniprot.org/uniprot/B1H3L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Secreted http://togogenome.org/gene/7719:LOC100179400 ^@ http://purl.uniprot.org/uniprot/H2Y1V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7719:LOC100182241 ^@ http://purl.uniprot.org/uniprot/F6V5N5 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7719:LOC100176698 ^@ http://purl.uniprot.org/uniprot/A0A1D8EIR2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 23 family. http://togogenome.org/gene/7719:LOC100185963 ^@ http://purl.uniprot.org/uniprot/F7AGA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:cbfb ^@ http://purl.uniprot.org/uniprot/Q4H3S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF-beta family.|||Nucleus http://togogenome.org/gene/7719:dll-b ^@ http://purl.uniprot.org/uniprot/Q9GP88 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100176838 ^@ http://purl.uniprot.org/uniprot/F7BB49 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/7719:p53/p73-a ^@ http://purl.uniprot.org/uniprot/Q4H301 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the p53 family.|||Binds 1 zinc ion per subunit.|||Nucleus http://togogenome.org/gene/7719:LOC100186223 ^@ http://purl.uniprot.org/uniprot/F6ZI02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/7719:zf(cxxc)-2 ^@ http://purl.uniprot.org/uniprot/Q1RPZ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100181450 ^@ http://purl.uniprot.org/uniprot/F6XIP9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/7719:LOC100178867 ^@ http://purl.uniprot.org/uniprot/A0A1W2WI90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7719:LOC100183713 ^@ http://purl.uniprot.org/uniprot/F7APZ8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 3 family.|||Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. http://togogenome.org/gene/7719:tak1/mapkkk7 ^@ http://purl.uniprot.org/uniprot/Q4H2Q7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/7719:LOC100182071 ^@ http://purl.uniprot.org/uniprot/F6PJX9 ^@ Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. http://togogenome.org/gene/7719:LOC100181148 ^@ http://purl.uniprot.org/uniprot/F6UAV0 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7719:syn ^@ http://purl.uniprot.org/uniprot/D1FXZ2 ^@ Similarity ^@ Belongs to the synapsin family. http://togogenome.org/gene/7719:LOC100185658 ^@ http://purl.uniprot.org/uniprot/H2Y2U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/7719:LOC100180277 ^@ http://purl.uniprot.org/uniprot/F6R1S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100179585 ^@ http://purl.uniprot.org/uniprot/H2XUE3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/7719:LOC100178529 ^@ http://purl.uniprot.org/uniprot/F6SCN2 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/7719:LOC100185869 ^@ http://purl.uniprot.org/uniprot/F6V9A1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/7719:LOC100049066 ^@ http://purl.uniprot.org/uniprot/A1Y9J6 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/7719:LOC100183484 ^@ http://purl.uniprot.org/uniprot/H2XZC8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100182889 ^@ http://purl.uniprot.org/uniprot/F6UUV9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/7719:LOC100183220 ^@ http://purl.uniprot.org/uniprot/H2XUY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:tbx20 ^@ http://purl.uniprot.org/uniprot/Q75UJ9 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7719:LOC100182651 ^@ http://purl.uniprot.org/uniprot/F6WAE5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178614 ^@ http://purl.uniprot.org/uniprot/F6WFD1 ^@ Similarity ^@ Belongs to the AF4 family. http://togogenome.org/gene/7719:LOC100178221 ^@ http://purl.uniprot.org/uniprot/H2XL19 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:cbf ^@ http://purl.uniprot.org/uniprot/Q4H3T4 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/7719:LOC445799 ^@ http://purl.uniprot.org/uniprot/Q6XZ09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Membrane http://togogenome.org/gene/7719:LOC100185470 ^@ http://purl.uniprot.org/uniprot/F6PII0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family.|||Mitochondrion membrane http://togogenome.org/gene/7719:smad6/7 ^@ http://purl.uniprot.org/uniprot/Q4H2T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100182622 ^@ http://purl.uniprot.org/uniprot/F6X600 ^@ Similarity|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Homodimer. http://togogenome.org/gene/7719:ar20 ^@ http://purl.uniprot.org/uniprot/Q8I7E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Cell projection|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||cytoskeleton http://togogenome.org/gene/7719:LOC100180662 ^@ http://purl.uniprot.org/uniprot/F6VKK3 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7719:LOC100177179 ^@ http://purl.uniprot.org/uniprot/H2XQL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/7719:LOC100179826 ^@ http://purl.uniprot.org/uniprot/F7BMF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SFR1/MEI5 family.|||Nucleus http://togogenome.org/gene/7719:LOC100178597 ^@ http://purl.uniprot.org/uniprot/F6ZJ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAL family.|||Membrane http://togogenome.org/gene/7719:LOC100169894 ^@ http://purl.uniprot.org/uniprot/Q0GBX2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:zf(ring/rbz)-1 ^@ http://purl.uniprot.org/uniprot/Q1RL70 ^@ Similarity ^@ Belongs to the RBR family. http://togogenome.org/gene/7719:LOC100180562 ^@ http://purl.uniprot.org/uniprot/F6X709 ^@ Function ^@ Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. http://togogenome.org/gene/7719:LOC100183724 ^@ http://purl.uniprot.org/uniprot/F6V3N9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100182976 ^@ http://purl.uniprot.org/uniprot/F7A2K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.|||Membrane http://togogenome.org/gene/7719:LOC100176678 ^@ http://purl.uniprot.org/uniprot/A0A1W2W8V2 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/7719:dll-a ^@ http://purl.uniprot.org/uniprot/Q9GP89 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:il-17-3 ^@ http://purl.uniprot.org/uniprot/Q6L5M4 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/7719:LOC100177381 ^@ http://purl.uniprot.org/uniprot/H2XS89 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/7719:LOC100179389 ^@ http://purl.uniprot.org/uniprot/F6TA16 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100179946 ^@ http://purl.uniprot.org/uniprot/F6PYG2 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/7719:LOC100187105 ^@ http://purl.uniprot.org/uniprot/A0A1W3JT00 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7719:bf-3 ^@ http://purl.uniprot.org/uniprot/Q5H874 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:LOC100185312 ^@ http://purl.uniprot.org/uniprot/F6ZKY0 ^@ Similarity ^@ Belongs to the SLAIN motif-containing family. http://togogenome.org/gene/7719:irx-b ^@ http://purl.uniprot.org/uniprot/Q4H3A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/7719:tbx1 ^@ http://purl.uniprot.org/uniprot/Q95YF5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7719:LOC100178249 ^@ http://purl.uniprot.org/uniprot/F7BPA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGME1 family.|||Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance.|||Mitochondrion http://togogenome.org/gene/7719:mapkk4 ^@ http://purl.uniprot.org/uniprot/Q4H381 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100180278 ^@ http://purl.uniprot.org/uniprot/F6TKR9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/7719:pdedelta ^@ http://purl.uniprot.org/uniprot/Q8SSZ0 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/7719:LOC100185381 ^@ http://purl.uniprot.org/uniprot/H2XV31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL54 family.|||Mitochondrion http://togogenome.org/gene/7719:LOC100184688 ^@ http://purl.uniprot.org/uniprot/F6XCK4 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/7719:hox12 ^@ http://purl.uniprot.org/uniprot/Q4H3D0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100181475 ^@ http://purl.uniprot.org/uniprot/F6STU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/7719:LOC100178512 ^@ http://purl.uniprot.org/uniprot/H2XP91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARMET family.|||Secreted http://togogenome.org/gene/7719:LOC100179281 ^@ http://purl.uniprot.org/uniprot/F6Y9H6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/7719:LOC100176892 ^@ http://purl.uniprot.org/uniprot/F6XSK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.|||Membrane http://togogenome.org/gene/7719:LOC100183862 ^@ http://purl.uniprot.org/uniprot/F6UYD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane http://togogenome.org/gene/7719:eph-like ^@ http://purl.uniprot.org/uniprot/Q4H3M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100182930 ^@ http://purl.uniprot.org/uniprot/F6QAE6 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/7719:LOC100184799 ^@ http://purl.uniprot.org/uniprot/A0A1W2W6D8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7719:erm ^@ http://purl.uniprot.org/uniprot/Q9NDR0 ^@ Subcellular Location Annotation ^@ Membrane|||cytoskeleton http://togogenome.org/gene/7719:LOC100178752 ^@ http://purl.uniprot.org/uniprot/F6Y7J8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:amt-1 ^@ http://purl.uniprot.org/uniprot/Q5VHU4|||http://purl.uniprot.org/uniprot/Q5VHU5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100184644 ^@ http://purl.uniprot.org/uniprot/F7AXE7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:LOC100180134 ^@ http://purl.uniprot.org/uniprot/H2XQ46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100182832 ^@ http://purl.uniprot.org/uniprot/A0A1W2WML0 ^@ Subcellular Location Annotation ^@ Nucleus|||perinuclear region http://togogenome.org/gene/7719:LOC100180121 ^@ http://purl.uniprot.org/uniprot/H2XVB3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100182353 ^@ http://purl.uniprot.org/uniprot/A0A1W2W3E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7719:LOC100181168 ^@ http://purl.uniprot.org/uniprot/A0A1W5BEL0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100186491 ^@ http://purl.uniprot.org/uniprot/F6TI69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100176340 ^@ http://purl.uniprot.org/uniprot/H2XWE5 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/7719:LOC100176514 ^@ http://purl.uniprot.org/uniprot/H2XMF0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/7719:LOC100183899 ^@ http://purl.uniprot.org/uniprot/F6ZSN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the malectin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:fli/erg4 ^@ http://purl.uniprot.org/uniprot/Q4H3K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC100176657 ^@ http://purl.uniprot.org/uniprot/F6PX91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7719:LOC100180370 ^@ http://purl.uniprot.org/uniprot/F6UFD9 ^@ Similarity|||Subunit ^@ Belongs to the NDUFAF4 family.|||Binds calmodulin. Interacts with NDUFAF3. http://togogenome.org/gene/7719:LOC100184495 ^@ http://purl.uniprot.org/uniprot/H2XY20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/7719:LOC100175733 ^@ http://purl.uniprot.org/uniprot/A0A1W2WJD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metaxin family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7719:LOC100186345 ^@ http://purl.uniprot.org/uniprot/F6U9X5 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/7719:LOC100175287 ^@ http://purl.uniprot.org/uniprot/H2XP25 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:il-17-1 ^@ http://purl.uniprot.org/uniprot/Q6L5M6 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/7719:LOC100184699 ^@ http://purl.uniprot.org/uniprot/A0A1W2W5N9 ^@ Subcellular Location Annotation ^@ trans-Golgi network http://togogenome.org/gene/7719:LOC100184440 ^@ http://purl.uniprot.org/uniprot/F6PIE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7719:if5-1 ^@ http://purl.uniprot.org/uniprot/Q1RPU8 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/7719:LOC100183052 ^@ http://purl.uniprot.org/uniprot/F6WUH0 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/7719:LOC100180220 ^@ http://purl.uniprot.org/uniprot/F6YB21 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/7719:LOC100183722 ^@ http://purl.uniprot.org/uniprot/F6UJM5 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7719:LOC100182402 ^@ http://purl.uniprot.org/uniprot/F6ZQX9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/7719:ci-tlr2 ^@ http://purl.uniprot.org/uniprot/C9K4U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/7719:LOC100177237 ^@ http://purl.uniprot.org/uniprot/Q8T3A0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:ror ^@ http://purl.uniprot.org/uniprot/A0A1W3JC90|||http://purl.uniprot.org/uniprot/Q4H2V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100179371 ^@ http://purl.uniprot.org/uniprot/H2Y3G1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100184593 ^@ http://purl.uniprot.org/uniprot/F6W2S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Mitochondrion membrane http://togogenome.org/gene/7719:LOC100187059 ^@ http://purl.uniprot.org/uniprot/F6YGL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane http://togogenome.org/gene/7719:dlc ^@ http://purl.uniprot.org/uniprot/Q8T894 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7719:meis ^@ http://purl.uniprot.org/uniprot/Q4H374 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/7719:ciatpsyna ^@ http://purl.uniprot.org/uniprot/Q8WPH6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/7719:LOC100180665 ^@ http://purl.uniprot.org/uniprot/F6RXZ8 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/7719:LOC100180004 ^@ http://purl.uniprot.org/uniprot/A0A1W5B8X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC778713 ^@ http://purl.uniprot.org/uniprot/Q4H319 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:zf(matrin)-2 ^@ http://purl.uniprot.org/uniprot/Q1RPZ2 ^@ Similarity ^@ Belongs to the SF3A2 family. http://togogenome.org/gene/7719:LOC100181797 ^@ http://purl.uniprot.org/uniprot/F6SN27 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/7719:LOC100177487 ^@ http://purl.uniprot.org/uniprot/F7A726 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/7719:LOC100176555 ^@ http://purl.uniprot.org/uniprot/F6YWN2 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA7 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7719:LOC100176866 ^@ http://purl.uniprot.org/uniprot/F6RDJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:e2f4/5 ^@ http://purl.uniprot.org/uniprot/Q4H3N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/7719:LOC108951060 ^@ http://purl.uniprot.org/uniprot/F7A3S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7719:LOC100181425 ^@ http://purl.uniprot.org/uniprot/F6QAV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/7719:LOC100185842 ^@ http://purl.uniprot.org/uniprot/F6Y782 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:prep ^@ http://purl.uniprot.org/uniprot/Q4H2X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100180479 ^@ http://purl.uniprot.org/uniprot/F7BIC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/7719:LOC100179230 ^@ http://purl.uniprot.org/uniprot/A0A1W3JM58 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/7719:lass6 ^@ http://purl.uniprot.org/uniprot/Q4H399 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7719:LOC100179092 ^@ http://purl.uniprot.org/uniprot/A0A1W2WP07 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/7719:ese ^@ http://purl.uniprot.org/uniprot/Q4H3L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:nf-x-like ^@ http://purl.uniprot.org/uniprot/Q4H346 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NFX1 family.|||Nucleus http://togogenome.org/gene/7719:hh2 ^@ http://purl.uniprot.org/uniprot/Q8MY56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/7719:LOC100185885 ^@ http://purl.uniprot.org/uniprot/F6UPX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic cobalamin transport proteins family.|||Secreted http://togogenome.org/gene/7719:zf(c3h)-17 ^@ http://purl.uniprot.org/uniprot/Q1RL44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unkempt family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100182819 ^@ http://purl.uniprot.org/uniprot/F6VUE2 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/7719:LOC100181589 ^@ http://purl.uniprot.org/uniprot/F6W667 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DENND6 family.|||Recycling endosome http://togogenome.org/gene/7719:LOC100176975 ^@ http://purl.uniprot.org/uniprot/H2XYB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:rps13 ^@ http://purl.uniprot.org/uniprot/Q8I7D6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/7719:LOC100179674 ^@ http://purl.uniprot.org/uniprot/F6Z2L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Late endosome membrane http://togogenome.org/gene/7719:uni3 ^@ http://purl.uniprot.org/uniprot/Q8T887 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tubulin family.|||Nucleus|||centriole|||cilium http://togogenome.org/gene/7719:LOC100181090 ^@ http://purl.uniprot.org/uniprot/F6XYB7 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/7719:LOC100180799 ^@ http://purl.uniprot.org/uniprot/F6QQ08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/7719:fgf-na1 ^@ http://purl.uniprot.org/uniprot/A4PIG6 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7719:LOC100180348 ^@ http://purl.uniprot.org/uniprot/F7B0J2 ^@ Similarity ^@ Belongs to the BCL7 family. http://togogenome.org/gene/7719:LOC100177287 ^@ http://purl.uniprot.org/uniprot/F6WA11 ^@ Similarity|||Subunit ^@ Belongs to the GILT family.|||Dimer; disulfide-linked. http://togogenome.org/gene/7719:LOC100185575 ^@ http://purl.uniprot.org/uniprot/F6U895 ^@ Similarity ^@ Belongs to the FAM167 (SEC) family. http://togogenome.org/gene/7719:myod ^@ http://purl.uniprot.org/uniprot/F6YKF5|||http://purl.uniprot.org/uniprot/Q4H359 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:pur-alpha/beta/gamma ^@ http://purl.uniprot.org/uniprot/Q4H2W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/7719:LOC100177133 ^@ http://purl.uniprot.org/uniprot/A0A1W3JBG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/7719:klp2 ^@ http://purl.uniprot.org/uniprot/F6WXC5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily. http://togogenome.org/gene/7719:LOC100183593 ^@ http://purl.uniprot.org/uniprot/Q86NA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane http://togogenome.org/gene/7719:LOC100185755 ^@ http://purl.uniprot.org/uniprot/A0A1W5B6T4 ^@ Similarity ^@ Belongs to the TCTP family. http://togogenome.org/gene/7719:LOC100181964 ^@ http://purl.uniprot.org/uniprot/F6RLB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-microseminoprotein family.|||Secreted http://togogenome.org/gene/7719:LOC100175466 ^@ http://purl.uniprot.org/uniprot/H2XJJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100179155 ^@ http://purl.uniprot.org/uniprot/H2XVG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HYLS1 family.|||centriole|||cilium http://togogenome.org/gene/7719:LOC100180093 ^@ http://purl.uniprot.org/uniprot/F6WIG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SMU1 family.|||Nucleus speckle http://togogenome.org/gene/7719:LOC100176872 ^@ http://purl.uniprot.org/uniprot/F6X598 ^@ Similarity|||Subunit ^@ Belongs to the complex I NDUFB5 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7719:LOC100175965 ^@ http://purl.uniprot.org/uniprot/F6XR12 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/7719:LOC100175300 ^@ http://purl.uniprot.org/uniprot/F6VEU9 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/7719:atbf ^@ http://purl.uniprot.org/uniprot/Q1RLB9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC778720 ^@ http://purl.uniprot.org/uniprot/Q4H308 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7719:LOC100177458 ^@ http://purl.uniprot.org/uniprot/A0A1W2WJ91 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/7719:LOC100125887 ^@ http://purl.uniprot.org/uniprot/A4ZW66 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC101242405 ^@ http://purl.uniprot.org/uniprot/H2XKN9 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/7719:LOC100186296 ^@ http://purl.uniprot.org/uniprot/H2XV30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC494390 ^@ http://purl.uniprot.org/uniprot/Q69HN9 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100176881 ^@ http://purl.uniprot.org/uniprot/F6Y6X7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/7719:LOC100176009 ^@ http://purl.uniprot.org/uniprot/F6PH07 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/7719:LOC100179460 ^@ http://purl.uniprot.org/uniprot/H2Y197 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100180099 ^@ http://purl.uniprot.org/uniprot/F6UXG6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100185968 ^@ http://purl.uniprot.org/uniprot/F6TBD6 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7719:LOC101243418 ^@ http://purl.uniprot.org/uniprot/F6YRR0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/7719:LOC100183866 ^@ http://purl.uniprot.org/uniprot/F6TA62 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/7719:LOC100186959 ^@ http://purl.uniprot.org/uniprot/F6UV18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/7719:LOC100176138 ^@ http://purl.uniprot.org/uniprot/F6SHG8 ^@ Similarity ^@ Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/7719:LOC100183747 ^@ http://purl.uniprot.org/uniprot/F6TIM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Clp1 family. Clp1 subfamily.|||Nucleus|||Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation. http://togogenome.org/gene/7719:uglcat2 ^@ http://purl.uniprot.org/uniprot/Q7YXB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100182535 ^@ http://purl.uniprot.org/uniprot/H2Y2G4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185465 ^@ http://purl.uniprot.org/uniprot/F6TMB1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7719:LOC100185665 ^@ http://purl.uniprot.org/uniprot/F6QPP6 ^@ Similarity ^@ Belongs to the CFAP157 family. http://togogenome.org/gene/7719:LOC100176028 ^@ http://purl.uniprot.org/uniprot/F7B568 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/7719:LOC100186853 ^@ http://purl.uniprot.org/uniprot/F6YPB3 ^@ Similarity|||Subunit ^@ Belongs to the TRAPPC13 family.|||Part of the multisubunit TRAPP (transport protein particle) complex. http://togogenome.org/gene/7719:tektinA1 ^@ http://purl.uniprot.org/uniprot/Q8T884 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/7719:LOC100178270 ^@ http://purl.uniprot.org/uniprot/F6RT14 ^@ Similarity ^@ Belongs to the RAMP family. http://togogenome.org/gene/7719:LOC100174998 ^@ http://purl.uniprot.org/uniprot/F6XLK3 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/7719:ftzf ^@ http://purl.uniprot.org/uniprot/F6WPT0|||http://purl.uniprot.org/uniprot/Q4H3G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR5 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC101243499 ^@ http://purl.uniprot.org/uniprot/H2XMB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.|||Mitochondrion membrane http://togogenome.org/gene/7719:ci-vp-r ^@ http://purl.uniprot.org/uniprot/B5UA19 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100185938 ^@ http://purl.uniprot.org/uniprot/A0A1W2W150 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7719:ap-2-like1 ^@ http://purl.uniprot.org/uniprot/Q4H3X0 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/7719:LOC100185602 ^@ http://purl.uniprot.org/uniprot/F6TXS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the kizuna family.|||Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.|||centrosome|||cilium basal body http://togogenome.org/gene/7719:LOC100176801 ^@ http://purl.uniprot.org/uniprot/H2Y026 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/7719:gli ^@ http://purl.uniprot.org/uniprot/Q4H3F1 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/7719:LOC100182614 ^@ http://purl.uniprot.org/uniprot/H2XN47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC101242260 ^@ http://purl.uniprot.org/uniprot/H2XTG7 ^@ Similarity ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family. http://togogenome.org/gene/7719:LOC100177386 ^@ http://purl.uniprot.org/uniprot/F7J186 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cholesterol 7-desaturase family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol. Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.|||Membrane http://togogenome.org/gene/7719:LOC100176507 ^@ http://purl.uniprot.org/uniprot/F6TCF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Cytoplasmic vesicle membrane|||Golgi apparatus membrane|||Membrane|||Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. http://togogenome.org/gene/7719:LOC100184399 ^@ http://purl.uniprot.org/uniprot/F6U1Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100185809 ^@ http://purl.uniprot.org/uniprot/F6YQ94 ^@ Function|||Similarity ^@ Belongs to the OPA3 family.|||May play some role in mitochondrial processes. http://togogenome.org/gene/7719:LOC100186332 ^@ http://purl.uniprot.org/uniprot/F6PMJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7719:LOC100183989 ^@ http://purl.uniprot.org/uniprot/H2XNA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100180482 ^@ http://purl.uniprot.org/uniprot/F6YYE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Chromosome|||Nucleus http://togogenome.org/gene/7719:LOC100186564 ^@ http://purl.uniprot.org/uniprot/F6YNG6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/7719:LOC100182348 ^@ http://purl.uniprot.org/uniprot/F6UIM4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100176701 ^@ http://purl.uniprot.org/uniprot/A0A1W3JUY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/7719:LOC100186653 ^@ http://purl.uniprot.org/uniprot/F6PKL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100177394 ^@ http://purl.uniprot.org/uniprot/A0A1W2WGH4 ^@ Similarity ^@ Belongs to the taxilin family. http://togogenome.org/gene/7719:LOC100185064 ^@ http://purl.uniprot.org/uniprot/A0A1W3JQT9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:foxa-a ^@ http://purl.uniprot.org/uniprot/Q4H3J7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC101243473 ^@ http://purl.uniprot.org/uniprot/F6SDC9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:LOC100181776 ^@ http://purl.uniprot.org/uniprot/H2Y3A1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100180404 ^@ http://purl.uniprot.org/uniprot/F7AQE7 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/7719:LOC100181225 ^@ http://purl.uniprot.org/uniprot/H2XSA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100175627 ^@ http://purl.uniprot.org/uniprot/H2Y3S3 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/7719:LOC100175299 ^@ http://purl.uniprot.org/uniprot/F6TZK8 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/7719:LOC100178517 ^@ http://purl.uniprot.org/uniprot/H2XMN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola http://togogenome.org/gene/7719:zf(nfx1) ^@ http://purl.uniprot.org/uniprot/F7ADU2|||http://purl.uniprot.org/uniprot/Q4H2G6 ^@ Similarity ^@ Belongs to the NFX1 family. http://togogenome.org/gene/7719:LOC778715 ^@ http://purl.uniprot.org/uniprot/Q4H317 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100180959 ^@ http://purl.uniprot.org/uniprot/F6Q521 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/7719:LOC100187036 ^@ http://purl.uniprot.org/uniprot/F6XF81 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179718 ^@ http://purl.uniprot.org/uniprot/F7B6X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100185960 ^@ http://purl.uniprot.org/uniprot/F6WUK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Catalyses the transfer of galactose onto proteins or lipids.|||Membrane http://togogenome.org/gene/7719:LOC100176356 ^@ http://purl.uniprot.org/uniprot/H2Y1M8 ^@ Similarity ^@ Belongs to the SNAPIN family. http://togogenome.org/gene/7719:foxf ^@ http://purl.uniprot.org/uniprot/Q4H3J0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100187383 ^@ http://purl.uniprot.org/uniprot/A0A1W2W7E4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/7719:LOC100175014 ^@ http://purl.uniprot.org/uniprot/F7BAE5 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100184780 ^@ http://purl.uniprot.org/uniprot/H2XJQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100178177 ^@ http://purl.uniprot.org/uniprot/F7AG43 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/7719:nfkbp105 ^@ http://purl.uniprot.org/uniprot/Q4H348 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7719:jak ^@ http://purl.uniprot.org/uniprot/Q4H3A3 ^@ Subcellular Location Annotation ^@ Endomembrane system http://togogenome.org/gene/7719:LOC100186663 ^@ http://purl.uniprot.org/uniprot/F7BDB7 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:thbsb ^@ http://purl.uniprot.org/uniprot/A2SY10 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100185085 ^@ http://purl.uniprot.org/uniprot/A0A1W3JJB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/7719:creb/atf-c ^@ http://purl.uniprot.org/uniprot/Q4H3R3|||http://purl.uniprot.org/uniprot/Q4H3R4|||http://purl.uniprot.org/uniprot/Q4H3R5|||http://purl.uniprot.org/uniprot/Q4H3R6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179012 ^@ http://purl.uniprot.org/uniprot/F6ZVT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/7719:LOC100183636 ^@ http://purl.uniprot.org/uniprot/F6SDC9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:LOC100187271 ^@ http://purl.uniprot.org/uniprot/F6QB99 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/7719:LOC100175966 ^@ http://purl.uniprot.org/uniprot/F6Q6Q9 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7719:LOC100182743 ^@ http://purl.uniprot.org/uniprot/A0A1W2WKY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/7719:dynlt1 ^@ http://purl.uniprot.org/uniprot/Q2PEE2 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7719:LOC100182395 ^@ http://purl.uniprot.org/uniprot/H2XL05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/7719:LOC100183571 ^@ http://purl.uniprot.org/uniprot/H2XQ94 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/7719:zf(tim10/ddp)-2 ^@ http://purl.uniprot.org/uniprot/H2Y167 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7719:LOC100180687 ^@ http://purl.uniprot.org/uniprot/H2XVL4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 23 family. http://togogenome.org/gene/7719:LOC100186064 ^@ http://purl.uniprot.org/uniprot/F6VAS2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7719:LOC100184789 ^@ http://purl.uniprot.org/uniprot/H2XRF2 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/7719:LOC100176016 ^@ http://purl.uniprot.org/uniprot/F6WUG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100179788 ^@ http://purl.uniprot.org/uniprot/F6ST69 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/7719:LOC100186871 ^@ http://purl.uniprot.org/uniprot/H2XVG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100184348 ^@ http://purl.uniprot.org/uniprot/F6U1J3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.|||Enterostatin has a biological activity as a satiety signal.|||Forms a 1:1 stoichiometric complex with pancreatic lipase.|||Secreted http://togogenome.org/gene/7719:ciepi-1 ^@ http://purl.uniprot.org/uniprot/Q9NKX7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100177665 ^@ http://purl.uniprot.org/uniprot/H2XR06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/7719:pk1 ^@ http://purl.uniprot.org/uniprot/Q9NDQ9 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/7719:LOC100177610 ^@ http://purl.uniprot.org/uniprot/F7ADF2 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/7719:emc ^@ http://purl.uniprot.org/uniprot/Q4H3M9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185572 ^@ http://purl.uniprot.org/uniprot/A0A1W2WA63 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7719:LOC100184763 ^@ http://purl.uniprot.org/uniprot/F7AEF1 ^@ Similarity ^@ Belongs to the DNAJC25 family. http://togogenome.org/gene/7719:LOC100177125 ^@ http://purl.uniprot.org/uniprot/F7BNG7 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/7719:LOC100181934 ^@ http://purl.uniprot.org/uniprot/F7BMN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF2/ABP1 family.|||nucleolus http://togogenome.org/gene/7719:amt-2 ^@ http://purl.uniprot.org/uniprot/Q5VHU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100179672 ^@ http://purl.uniprot.org/uniprot/F6YEI6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100175427 ^@ http://purl.uniprot.org/uniprot/H2XP99 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:nat1 ^@ http://purl.uniprot.org/uniprot/D8FSZ9 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/7719:LOC104266855 ^@ http://purl.uniprot.org/uniprot/F6ZQ58 ^@ Similarity ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. http://togogenome.org/gene/7719:LOC100182069 ^@ http://purl.uniprot.org/uniprot/F6Q9J1 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/7719:hh1 ^@ http://purl.uniprot.org/uniprot/Q8MY57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/7719:LOC100179843 ^@ http://purl.uniprot.org/uniprot/H2XY39 ^@ Similarity ^@ Belongs to the TACO1 family. http://togogenome.org/gene/7719:LOC100185739 ^@ http://purl.uniprot.org/uniprot/F6QRJ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Interacts with PPIF; the interaction is impaired by CsA.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100184511 ^@ http://purl.uniprot.org/uniprot/F6SYL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/7719:LOC100176735 ^@ http://purl.uniprot.org/uniprot/A0A1W2W3R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100179714 ^@ http://purl.uniprot.org/uniprot/H2XYJ2 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/7719:LOC778832 ^@ http://purl.uniprot.org/uniprot/Q4H2G1 ^@ Function|||Similarity ^@ Belongs to the BMT2 family.|||S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/7719:LOC100187068 ^@ http://purl.uniprot.org/uniprot/A0A1W3JSW3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100184807 ^@ http://purl.uniprot.org/uniprot/F6T113 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:rtn ^@ http://purl.uniprot.org/uniprot/F6U212|||http://purl.uniprot.org/uniprot/Q7RTJ6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100179536 ^@ http://purl.uniprot.org/uniprot/F6VFA0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/7719:LOC100181328 ^@ http://purl.uniprot.org/uniprot/F6VMU0 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/7719:LOC100185846 ^@ http://purl.uniprot.org/uniprot/H2XL53 ^@ Similarity ^@ Belongs to the costars family. http://togogenome.org/gene/7719:rbdlc ^@ http://purl.uniprot.org/uniprot/Q8T899 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/7719:LOC100182742 ^@ http://purl.uniprot.org/uniprot/F7BHM4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/7719:LOC100179418 ^@ http://purl.uniprot.org/uniprot/F6VTS4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7719:hox3 ^@ http://purl.uniprot.org/uniprot/A0A1W3JJN3|||http://purl.uniprot.org/uniprot/Q9XZR2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100177347 ^@ http://purl.uniprot.org/uniprot/F6T7Y6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100178355 ^@ http://purl.uniprot.org/uniprot/H2XRD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7719:LOC100186791 ^@ http://purl.uniprot.org/uniprot/F6SU68 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7719:LOC100181593 ^@ http://purl.uniprot.org/uniprot/F6VIC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7719:acl ^@ http://purl.uniprot.org/uniprot/Q9NDQ3 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.|||Homotetramer.|||In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/7719:th ^@ http://purl.uniprot.org/uniprot/Q5ZNC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.|||perinuclear region http://togogenome.org/gene/7719:LOC100179758 ^@ http://purl.uniprot.org/uniprot/F6ZT75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:tropm1 ^@ http://purl.uniprot.org/uniprot/Q9NDQ4 ^@ Similarity ^@ Belongs to the tropomyosin family. http://togogenome.org/gene/7719:erd2 ^@ http://purl.uniprot.org/uniprot/Q8I7E2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:kif3b ^@ http://purl.uniprot.org/uniprot/F7B875 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/7719:LOC100175749 ^@ http://purl.uniprot.org/uniprot/A0A1W2VZT1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/7719:LOC100186478 ^@ http://purl.uniprot.org/uniprot/F7ARW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NKAIN family.|||Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100180163 ^@ http://purl.uniprot.org/uniprot/F6ZBR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP2 family.|||Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.|||Membrane http://togogenome.org/gene/7719:p53/p73-b ^@ http://purl.uniprot.org/uniprot/Q4H2Z8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the p53 family.|||Binds 1 zinc ion per subunit.|||Nucleus http://togogenome.org/gene/7719:LOC104266013 ^@ http://purl.uniprot.org/uniprot/F6UMV2 ^@ Similarity ^@ Belongs to the NXPE family. http://togogenome.org/gene/7719:LOC100183815 ^@ http://purl.uniprot.org/uniprot/F6V5Y1 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/7719:LOC100181283 ^@ http://purl.uniprot.org/uniprot/H2XNG5 ^@ Similarity ^@ Belongs to the polysaccharide monooxygenase AA13 family. http://togogenome.org/gene/7719:LOC100180468 ^@ http://purl.uniprot.org/uniprot/F6PWR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AMY1 family.|||Nucleus http://togogenome.org/gene/7719:LOC100178572 ^@ http://purl.uniprot.org/uniprot/H2XTQ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/7719:LOC100185166 ^@ http://purl.uniprot.org/uniprot/F6V437 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/7719:LOC100182572 ^@ http://purl.uniprot.org/uniprot/F6YIY8 ^@ Similarity ^@ Belongs to the bystin family. http://togogenome.org/gene/7719:rpe65 ^@ http://purl.uniprot.org/uniprot/Q2PE71 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/7719:LOC100180936 ^@ http://purl.uniprot.org/uniprot/H2XYP3 ^@ Similarity ^@ Belongs to the synembryn family. http://togogenome.org/gene/7719:ci-cadherin ^@ http://purl.uniprot.org/uniprot/Q9NL47 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane http://togogenome.org/gene/7719:sfrp3/4-a ^@ http://purl.uniprot.org/uniprot/Q4H2U3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100185551 ^@ http://purl.uniprot.org/uniprot/F6TTN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100184231 ^@ http://purl.uniprot.org/uniprot/F6RGI4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/7719:ck2a ^@ http://purl.uniprot.org/uniprot/Q8T3S5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100183497 ^@ http://purl.uniprot.org/uniprot/Q52V41 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100183007 ^@ http://purl.uniprot.org/uniprot/F6YE24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||Required for the processing of the 27S pre-rRNA.|||nucleolus http://togogenome.org/gene/7719:LOC100176704 ^@ http://purl.uniprot.org/uniprot/F6ZGT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF8 family.|||Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II). http://togogenome.org/gene/7719:nr1 ^@ http://purl.uniprot.org/uniprot/O77154 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100179858 ^@ http://purl.uniprot.org/uniprot/F6YFI7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100182258 ^@ http://purl.uniprot.org/uniprot/F7BGH4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100178975 ^@ http://purl.uniprot.org/uniprot/F6U8M8 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7719:LOC100180780 ^@ http://purl.uniprot.org/uniprot/F7AY51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100179878 ^@ http://purl.uniprot.org/uniprot/F6R2I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane http://togogenome.org/gene/7719:LOC100177203 ^@ http://purl.uniprot.org/uniprot/F6XZ93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100184809 ^@ http://purl.uniprot.org/uniprot/A0A1W2WGY3 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/7719:LOC100182576 ^@ http://purl.uniprot.org/uniprot/H2XML0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC3 family.|||Component of the ER membrane protein complex (EMC).|||Membrane http://togogenome.org/gene/7719:LOC100176467 ^@ http://purl.uniprot.org/uniprot/F7AD97 ^@ Similarity ^@ Belongs to the VPS52 family. http://togogenome.org/gene/7719:LOC100182780 ^@ http://purl.uniprot.org/uniprot/H2XWP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/7719:LOC100178974 ^@ http://purl.uniprot.org/uniprot/A0A1W2WD79 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/7719:LOC778723 ^@ http://purl.uniprot.org/uniprot/Q4H305 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7719:LOC100181027 ^@ http://purl.uniprot.org/uniprot/A0A1W2WEA2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK2 subfamily.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Mitochondrion intermembrane space|||Monomer.|||cytosol http://togogenome.org/gene/7719:LOC100182021 ^@ http://purl.uniprot.org/uniprot/F6ZBY5 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/7719:LOC100176210 ^@ http://purl.uniprot.org/uniprot/F6WPS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Has a role in transport between endoplasmic reticulum and Golgi.|||Membrane http://togogenome.org/gene/7719:r27a ^@ http://purl.uniprot.org/uniprot/A0A1W3JRI0|||http://purl.uniprot.org/uniprot/Q8I7E0 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/7719:LOC100180750 ^@ http://purl.uniprot.org/uniprot/F6RS86 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:nf-e2 ^@ http://purl.uniprot.org/uniprot/Q4H350|||http://purl.uniprot.org/uniprot/Q4H351 ^@ Similarity ^@ Belongs to the bZIP family. CNC subfamily. http://togogenome.org/gene/7719:LOC104265886 ^@ http://purl.uniprot.org/uniprot/A0A1W3JEA6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:b3galt6 ^@ http://purl.uniprot.org/uniprot/Q256Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100178767 ^@ http://purl.uniprot.org/uniprot/F6QN34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/7719:LOC100184190 ^@ http://purl.uniprot.org/uniprot/F6TWX7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/7719:LOC100176092 ^@ http://purl.uniprot.org/uniprot/F6T6I0|||http://purl.uniprot.org/uniprot/F6T6J2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7719:LOC100185896 ^@ http://purl.uniprot.org/uniprot/F6XDP4 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/7719:smad4 ^@ http://purl.uniprot.org/uniprot/Q4H2T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100176818 ^@ http://purl.uniprot.org/uniprot/F6RGE7 ^@ Similarity ^@ Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/7719:ci-htf-1 ^@ http://purl.uniprot.org/uniprot/A0A1W5BCV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/7719:zf(bbox/ring)-1 ^@ http://purl.uniprot.org/uniprot/Q1RLI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIM/RBCC family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100184308 ^@ http://purl.uniprot.org/uniprot/F7BMV4 ^@ Similarity ^@ Belongs to the CENP-N/CHL4 family. http://togogenome.org/gene/7719:LOC100177815 ^@ http://purl.uniprot.org/uniprot/F6QGB8 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/7719:LOC100187445 ^@ http://purl.uniprot.org/uniprot/F6SDQ3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/7719:LOC100186176 ^@ http://purl.uniprot.org/uniprot/F6RBI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC100187200 ^@ http://purl.uniprot.org/uniprot/F6UP98 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:LOC100175363 ^@ http://purl.uniprot.org/uniprot/F6TTQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100182007 ^@ http://purl.uniprot.org/uniprot/F6SDC9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:foxB ^@ http://purl.uniprot.org/uniprot/Q70VZ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100180074 ^@ http://purl.uniprot.org/uniprot/H2XVJ5 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7719:LOC100180640 ^@ http://purl.uniprot.org/uniprot/A0A1W3JEY8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/7719:zf(phd)-1 ^@ http://purl.uniprot.org/uniprot/Q4H2G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SAYP family.|||Nucleus http://togogenome.org/gene/7719:ephd ^@ http://purl.uniprot.org/uniprot/Q4H3M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100182924 ^@ http://purl.uniprot.org/uniprot/F6TX13 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/7719:tgfbeta2 ^@ http://purl.uniprot.org/uniprot/Q4H2P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||extracellular matrix http://togogenome.org/gene/7719:LOC100187398 ^@ http://purl.uniprot.org/uniprot/F6YBU7 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1. http://togogenome.org/gene/7719:LOC100183684 ^@ http://purl.uniprot.org/uniprot/F6ZFW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. http://togogenome.org/gene/7719:LOC100184515 ^@ http://purl.uniprot.org/uniprot/F6RUN6 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. http://togogenome.org/gene/7719:LOC100181830 ^@ http://purl.uniprot.org/uniprot/F6ZX12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100180448 ^@ http://purl.uniprot.org/uniprot/A0A1W3JD12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.|||Peroxisome membrane http://togogenome.org/gene/7719:ck-1a1 ^@ http://purl.uniprot.org/uniprot/Q60FD3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100184966 ^@ http://purl.uniprot.org/uniprot/F6YAZ4 ^@ Similarity ^@ Belongs to the histone H2B family. http://togogenome.org/gene/7719:LOC100184213 ^@ http://purl.uniprot.org/uniprot/F6URX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100180713 ^@ http://purl.uniprot.org/uniprot/H2Y0C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/7719:LOC100175259 ^@ http://purl.uniprot.org/uniprot/F6XWH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100176736 ^@ http://purl.uniprot.org/uniprot/F6XCZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/7719:LOC100186950 ^@ http://purl.uniprot.org/uniprot/F6X7W0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.|||Mitochondrion http://togogenome.org/gene/7719:pax3/7-like ^@ http://purl.uniprot.org/uniprot/Q4H2Y9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:wnt-a ^@ http://purl.uniprot.org/uniprot/Q4H310 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7719:LOC100180883 ^@ http://purl.uniprot.org/uniprot/F6THA9 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7719:LOC100184214 ^@ http://purl.uniprot.org/uniprot/F7AZS2 ^@ Similarity ^@ Belongs to the FBXO45/Fsn family. http://togogenome.org/gene/7719:LOC100182351 ^@ http://purl.uniprot.org/uniprot/F6SS10 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:n ^@ http://purl.uniprot.org/uniprot/Q2L697 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOTCH family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Nucleus http://togogenome.org/gene/7719:LOC100181722 ^@ http://purl.uniprot.org/uniprot/F6UXP7 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/7719:LOC100186372 ^@ http://purl.uniprot.org/uniprot/F6WQD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRIPT family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100185418 ^@ http://purl.uniprot.org/uniprot/F6XGT0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7719:LOC100183977 ^@ http://purl.uniprot.org/uniprot/F6XHN7 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:LOC100185445 ^@ http://purl.uniprot.org/uniprot/F6XA49 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/7719:LOC100186487 ^@ http://purl.uniprot.org/uniprot/F6S578 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tim44 family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100176951 ^@ http://purl.uniprot.org/uniprot/F6Y8L3 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/7719:cgrp-rcp ^@ http://purl.uniprot.org/uniprot/Q8T885 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC9 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/7719:ephrina-c ^@ http://purl.uniprot.org/uniprot/Q4H3M0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:uhrf2 ^@ http://purl.uniprot.org/uniprot/Q4H2N4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC104266814 ^@ http://purl.uniprot.org/uniprot/F6XBW4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7719:LOC100177611 ^@ http://purl.uniprot.org/uniprot/H2XTL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7719:LOC100183367 ^@ http://purl.uniprot.org/uniprot/F6R8X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Dynein axonemal particle http://togogenome.org/gene/7719:LOC104265388 ^@ http://purl.uniprot.org/uniprot/F6YHR6 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/7719:con ^@ http://purl.uniprot.org/uniprot/I7HGJ1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. http://togogenome.org/gene/7719:LOC100186374 ^@ http://purl.uniprot.org/uniprot/F7B0I1 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/7719:LOC100179647 ^@ http://purl.uniprot.org/uniprot/F6WN20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the POC5 family.|||Essential for the assembly of the distal half of centrioles, required for centriole elongation.|||centriole http://togogenome.org/gene/7719:LOC100181289 ^@ http://purl.uniprot.org/uniprot/F7ARV5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:nox4 ^@ http://purl.uniprot.org/uniprot/Q4R1Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100180005 ^@ http://purl.uniprot.org/uniprot/H2XN55 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:LOC100175566 ^@ http://purl.uniprot.org/uniprot/F7AN54 ^@ Similarity ^@ Belongs to the TTC19 family. http://togogenome.org/gene/7719:LOC100182293 ^@ http://purl.uniprot.org/uniprot/F6V6S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.|||Homotetramer.|||Mitochondrion matrix http://togogenome.org/gene/7719:LOC100175596 ^@ http://purl.uniprot.org/uniprot/F6TT18 ^@ Similarity ^@ Belongs to the tropomyosin family. http://togogenome.org/gene/7719:LOC100181796 ^@ http://purl.uniprot.org/uniprot/A0A1W5BA34 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 6A family. http://togogenome.org/gene/7719:zf(c3h)-5 ^@ http://purl.uniprot.org/uniprot/Q1RLG4 ^@ Similarity ^@ Belongs to the dus family. Dus3 subfamily. http://togogenome.org/gene/7719:LOC100184903 ^@ http://purl.uniprot.org/uniprot/H2Y318 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/7719:LOC100175981 ^@ http://purl.uniprot.org/uniprot/F6PVM8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/7719:LOC100186976 ^@ http://purl.uniprot.org/uniprot/H2XL54 ^@ Similarity ^@ Belongs to the calcium channel subunit alpha-2/delta family. http://togogenome.org/gene/7719:LOC100175937 ^@ http://purl.uniprot.org/uniprot/F6RPI4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100187194 ^@ http://purl.uniprot.org/uniprot/H2XW11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/7719:LOC100176136 ^@ http://purl.uniprot.org/uniprot/F6Y0X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:jnk ^@ http://purl.uniprot.org/uniprot/Q4H3A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/7719:LOC100186763 ^@ http://purl.uniprot.org/uniprot/F7A172 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100176240 ^@ http://purl.uniprot.org/uniprot/F6VZQ9 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/7719:LOC100184880 ^@ http://purl.uniprot.org/uniprot/F6U7Z2 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/7719:gcnf ^@ http://purl.uniprot.org/uniprot/Q4H3F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7719:zf(traf/ring)-2 ^@ http://purl.uniprot.org/uniprot/Q1RLF0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:LOC100176329 ^@ http://purl.uniprot.org/uniprot/F6TK16 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100182760 ^@ http://purl.uniprot.org/uniprot/F6TQT4 ^@ Similarity ^@ Belongs to the glutaminase family. http://togogenome.org/gene/7719:LOC100180919 ^@ http://purl.uniprot.org/uniprot/H2XJX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/7719:LOC100175015 ^@ http://purl.uniprot.org/uniprot/H2XLQ3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. http://togogenome.org/gene/7719:phox2 ^@ http://purl.uniprot.org/uniprot/Q19AW1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100186615 ^@ http://purl.uniprot.org/uniprot/F6RGJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7719:LOC100179729 ^@ http://purl.uniprot.org/uniprot/F6U8R6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100181119 ^@ http://purl.uniprot.org/uniprot/F6Y7J1 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:LOC445731 ^@ http://purl.uniprot.org/uniprot/Q6XQM6 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/7719:LOC100187093 ^@ http://purl.uniprot.org/uniprot/H2Y2X3 ^@ Similarity ^@ Belongs to the ependymin family. http://togogenome.org/gene/7719:LOC778994 ^@ http://purl.uniprot.org/uniprot/Q32TF7 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/7719:LOC100185653 ^@ http://purl.uniprot.org/uniprot/F6U516 ^@ Similarity ^@ Belongs to the ADP-ribosylglycohydrolase family. http://togogenome.org/gene/7719:zf(cchc)-17 ^@ http://purl.uniprot.org/uniprot/A0A1W3JL17|||http://purl.uniprot.org/uniprot/Q1RLA8 ^@ Similarity ^@ Belongs to the lin-28 family. http://togogenome.org/gene/7719:LOC100176513 ^@ http://purl.uniprot.org/uniprot/A0A140TAT7 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/7719:LOC100183957 ^@ http://purl.uniprot.org/uniprot/A0A1W2WN02 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/7719:LOC100182515 ^@ http://purl.uniprot.org/uniprot/H2XS26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/7719:LOC100182577 ^@ http://purl.uniprot.org/uniprot/F6ZL64 ^@ Similarity ^@ Belongs to the RUS1 family. http://togogenome.org/gene/7719:LOC100183594 ^@ http://purl.uniprot.org/uniprot/F6TML4 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/7719:cior2 ^@ http://purl.uniprot.org/uniprot/H7CE69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100177874 ^@ http://purl.uniprot.org/uniprot/H2Y2X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC1 family.|||flagellum axoneme http://togogenome.org/gene/7719:s-themis-b ^@ http://purl.uniprot.org/uniprot/B1Q455 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polycystin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:fxr ^@ http://purl.uniprot.org/uniprot/Q4H3G1 ^@ Similarity ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily. http://togogenome.org/gene/7719:LOC100179243 ^@ http://purl.uniprot.org/uniprot/F6QH68 ^@ Function|||Similarity ^@ Belongs to the DDAH family.|||Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. http://togogenome.org/gene/7719:otp ^@ http://purl.uniprot.org/uniprot/Q4H304 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:msxb ^@ http://purl.uniprot.org/uniprot/Q9XZR1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC101243330 ^@ http://purl.uniprot.org/uniprot/F6TV26 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/7719:LOC100177365 ^@ http://purl.uniprot.org/uniprot/F6T485 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/7719:LOC100183950 ^@ http://purl.uniprot.org/uniprot/F6XEA5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7719:ephrina-d ^@ http://purl.uniprot.org/uniprot/Q4H3L9 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100179556 ^@ http://purl.uniprot.org/uniprot/F6YDF4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/7719:LOC100186836 ^@ http://purl.uniprot.org/uniprot/F6PK03 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:zf(c2h2)-17 ^@ http://purl.uniprot.org/uniprot/H2XVS3|||http://purl.uniprot.org/uniprot/Q4H2K2 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/7719:LOC100183423 ^@ http://purl.uniprot.org/uniprot/F6Q9R4 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7719:LOC100176208 ^@ http://purl.uniprot.org/uniprot/F6YKZ8 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100184049 ^@ http://purl.uniprot.org/uniprot/F6SC91 ^@ Similarity ^@ Belongs to the CENP-C/MIF2 family. http://togogenome.org/gene/7719:LOC100182410 ^@ http://purl.uniprot.org/uniprot/H2XNW6 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/7719:LOC100183293 ^@ http://purl.uniprot.org/uniprot/F6XTV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFS-II family.|||Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.|||Nucleus http://togogenome.org/gene/7719:LOC100186067 ^@ http://purl.uniprot.org/uniprot/A0A1W3JGQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/7719:LOC100181257 ^@ http://purl.uniprot.org/uniprot/F7A160 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/7719:LOC100181117 ^@ http://purl.uniprot.org/uniprot/F7BCQ0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100182745 ^@ http://purl.uniprot.org/uniprot/F7AW67 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/7719:ck2b ^@ http://purl.uniprot.org/uniprot/Q967X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/7719:hsf ^@ http://purl.uniprot.org/uniprot/Q4H3C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/7719:zf(c2h2)-130 ^@ http://purl.uniprot.org/uniprot/Q1RL92 ^@ Similarity ^@ Belongs to the teashirt C2H2-type zinc-finger protein family. http://togogenome.org/gene/7719:LOC100186298 ^@ http://purl.uniprot.org/uniprot/F6Z589 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/7719:gabpalpha ^@ http://purl.uniprot.org/uniprot/Q4H3F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:prox-b ^@ http://purl.uniprot.org/uniprot/Q4H2W8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:lmx-like ^@ http://purl.uniprot.org/uniprot/Q4H388 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:tgfbeta-na2 ^@ http://purl.uniprot.org/uniprot/Q4H2P6 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100185096 ^@ http://purl.uniprot.org/uniprot/F6PZ06 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/7719:LOC100183082 ^@ http://purl.uniprot.org/uniprot/F6WP45 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/7719:LOC100182060 ^@ http://purl.uniprot.org/uniprot/H2XMI0 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7719:LOC100186863 ^@ http://purl.uniprot.org/uniprot/F6XH93 ^@ Similarity ^@ Belongs to the GIPC family. http://togogenome.org/gene/7719:LOC100181480 ^@ http://purl.uniprot.org/uniprot/A0A1W2WHH8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100178377 ^@ http://purl.uniprot.org/uniprot/F6TM19 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/7719:jun ^@ http://purl.uniprot.org/uniprot/Q4H3A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC104265829 ^@ http://purl.uniprot.org/uniprot/F6T0K4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/7719:LOC100179397 ^@ http://purl.uniprot.org/uniprot/F7BEK9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100183764 ^@ http://purl.uniprot.org/uniprot/A0A1W5B7N8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/7719:LOC100182620 ^@ http://purl.uniprot.org/uniprot/H2XLD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/7719:macho1 ^@ http://purl.uniprot.org/uniprot/Q8WSQ0 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/7719:LOC100175452 ^@ http://purl.uniprot.org/uniprot/F6UAX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/7719:LOC100182009 ^@ http://purl.uniprot.org/uniprot/A0A1W5BHL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100184661 ^@ http://purl.uniprot.org/uniprot/F6TJA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:nk4 ^@ http://purl.uniprot.org/uniprot/Q4H342 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185987 ^@ http://purl.uniprot.org/uniprot/F6ZWB0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:noggin ^@ http://purl.uniprot.org/uniprot/Q4H336 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the noggin family.|||Secreted http://togogenome.org/gene/7719:LOC100183822 ^@ http://purl.uniprot.org/uniprot/F6VCG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 26 family.|||Nucleus http://togogenome.org/gene/7719:ciarr ^@ http://purl.uniprot.org/uniprot/Q8MYB1 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7719:meta1 ^@ http://purl.uniprot.org/uniprot/Q9BLJ1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100186746 ^@ http://purl.uniprot.org/uniprot/A0A1W2WF05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG3 family.|||Cytoplasm http://togogenome.org/gene/7719:zf(dhhc)-2 ^@ http://purl.uniprot.org/uniprot/Q1RPV9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Cytoplasmic vesicle membrane|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7719:otx2 ^@ http://purl.uniprot.org/uniprot/Q4H303 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100181260 ^@ http://purl.uniprot.org/uniprot/F7B4F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/7719:LOC101242339 ^@ http://purl.uniprot.org/uniprot/F6V2P6 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:LOC100179352 ^@ http://purl.uniprot.org/uniprot/F6XCL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/7719:LOC100187088 ^@ http://purl.uniprot.org/uniprot/F6QZ30 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:erk5 ^@ http://purl.uniprot.org/uniprot/Q4H3L3 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/7719:LOC108949285 ^@ http://purl.uniprot.org/uniprot/Q0GBX4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100183463 ^@ http://purl.uniprot.org/uniprot/F6QDJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:gpb5 ^@ http://purl.uniprot.org/uniprot/C6SUS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7719:LOC100186509 ^@ http://purl.uniprot.org/uniprot/F6R579 ^@ Similarity ^@ Belongs to the DDIT4 family. http://togogenome.org/gene/7719:ci14-3-3 ^@ http://purl.uniprot.org/uniprot/Q9NKX5 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/7719:LOC100186610 ^@ http://purl.uniprot.org/uniprot/A0A1W2WP01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7719:bmp5/7-like ^@ http://purl.uniprot.org/uniprot/Q4H3U4 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC778624 ^@ http://purl.uniprot.org/uniprot/L7N0V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100181568 ^@ http://purl.uniprot.org/uniprot/F6UPC7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/7719:hox4 ^@ http://purl.uniprot.org/uniprot/Q4H3C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100180566 ^@ http://purl.uniprot.org/uniprot/F6YXZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 3-oxoacid CoA-transferase family.|||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.|||Mitochondrion http://togogenome.org/gene/7719:LOC100177581 ^@ http://purl.uniprot.org/uniprot/F6YKR9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:csd ^@ http://purl.uniprot.org/uniprot/Q8T8A6 ^@ Similarity|||Subunit ^@ Belongs to the group II decarboxylase family.|||Homodimer. http://togogenome.org/gene/7719:LOC494373 ^@ http://purl.uniprot.org/uniprot/Q69HR0 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7719:LOC100186893 ^@ http://purl.uniprot.org/uniprot/F6TFV0 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/7719:LOC100183825 ^@ http://purl.uniprot.org/uniprot/F6TIH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100177098 ^@ http://purl.uniprot.org/uniprot/F6ZYZ9 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:zf(c3h)-2 ^@ http://purl.uniprot.org/uniprot/F6YTX7 ^@ Similarity ^@ Belongs to the ZC3H15/TMA46 family. http://togogenome.org/gene/7719:ets ^@ http://purl.uniprot.org/uniprot/Q4H3K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC104266248 ^@ http://purl.uniprot.org/uniprot/F6SNN8 ^@ Similarity ^@ Belongs to the SAP18 family. http://togogenome.org/gene/7719:LOC100179482 ^@ http://purl.uniprot.org/uniprot/F6RF58 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/7719:LOC100181511 ^@ http://purl.uniprot.org/uniprot/F6UK51 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/7719:LOC100185453 ^@ http://purl.uniprot.org/uniprot/F6ZX23 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100179818 ^@ http://purl.uniprot.org/uniprot/A0A1W2W8Q4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC4 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:LOC100175511 ^@ http://purl.uniprot.org/uniprot/F6TUN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.|||Belongs to the mitochondrion-specific ribosomal protein mL64 family.|||Mitochondrion|||Nucleus http://togogenome.org/gene/7719:zf(traf/ring)-4 ^@ http://purl.uniprot.org/uniprot/Q1RLC3 ^@ Similarity ^@ Belongs to the ZFTRAF1 family. http://togogenome.org/gene/7719:LOC100177190 ^@ http://purl.uniprot.org/uniprot/F6U621 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/7719:LOC100187015 ^@ http://purl.uniprot.org/uniprot/F6UCW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNF10 family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100179349 ^@ http://purl.uniprot.org/uniprot/F6SYI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Integrator subunit 8 family.|||Nucleus http://togogenome.org/gene/7719:LOC100182802 ^@ http://purl.uniprot.org/uniprot/H2XTN5 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/7719:LOC100186018 ^@ http://purl.uniprot.org/uniprot/F6QZB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100175410 ^@ http://purl.uniprot.org/uniprot/H2Y2D7 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/7719:LOC100185019 ^@ http://purl.uniprot.org/uniprot/F7AZT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/7719:aer61b ^@ http://purl.uniprot.org/uniprot/Q5NDL7 ^@ Similarity ^@ Belongs to the glycosyltransferase 61 family. http://togogenome.org/gene/7719:LOC100187183 ^@ http://purl.uniprot.org/uniprot/F7B5E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/7719:LOC100179303 ^@ http://purl.uniprot.org/uniprot/F6QP54 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:zf(bed)-3 ^@ http://purl.uniprot.org/uniprot/Q1RLB7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:ci-nt-a ^@ http://purl.uniprot.org/uniprot/F5XVE6 ^@ Miscellaneous ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry. http://togogenome.org/gene/7719:foxh-a ^@ http://purl.uniprot.org/uniprot/Q4H3I8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100187325 ^@ http://purl.uniprot.org/uniprot/H2XLS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100183458 ^@ http://purl.uniprot.org/uniprot/A0A1W2WIY7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100180144 ^@ http://purl.uniprot.org/uniprot/F6RNS7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/7719:LOC100182675 ^@ http://purl.uniprot.org/uniprot/F7A7T2 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/7719:LOC100178514 ^@ http://purl.uniprot.org/uniprot/H2Y0H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/7719:LOC100182838 ^@ http://purl.uniprot.org/uniprot/F6T886 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/7719:LOC100184693 ^@ http://purl.uniprot.org/uniprot/F6R589 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/7719:LOC100178735 ^@ http://purl.uniprot.org/uniprot/A0A1W2W8J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HRG family.|||Membrane|||phagosome membrane http://togogenome.org/gene/7719:LOC100180720 ^@ http://purl.uniprot.org/uniprot/H2XWU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/7719:fz4 ^@ http://purl.uniprot.org/uniprot/Q4H3F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/7719:LOC100181786 ^@ http://purl.uniprot.org/uniprot/F7AP23 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/7719:LOC100180305 ^@ http://purl.uniprot.org/uniprot/H2XY81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/7719:tgfbeta-na4 ^@ http://purl.uniprot.org/uniprot/A4PIG2 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100177058 ^@ http://purl.uniprot.org/uniprot/F7BBQ0 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/7719:LOC100184069 ^@ http://purl.uniprot.org/uniprot/H2XPT5 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/7719:LOC100178876 ^@ http://purl.uniprot.org/uniprot/Q6E3K4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100176205 ^@ http://purl.uniprot.org/uniprot/H2Y3T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC101242566 ^@ http://purl.uniprot.org/uniprot/F7BNU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG14 family.|||Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane http://togogenome.org/gene/7719:hnf6 ^@ http://purl.uniprot.org/uniprot/Q4H3D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100184967 ^@ http://purl.uniprot.org/uniprot/F6YK29 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.|||Binds 1 Mg(2+) ion per subunit.|||GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.|||Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.|||Mitochondrion http://togogenome.org/gene/7719:LOC100181925 ^@ http://purl.uniprot.org/uniprot/H2XTM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.|||Nucleus http://togogenome.org/gene/7719:LOC100178461 ^@ http://purl.uniprot.org/uniprot/F6ZL37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane|||Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. http://togogenome.org/gene/7719:LOC100178291 ^@ http://purl.uniprot.org/uniprot/F6WFD9 ^@ Similarity ^@ Belongs to the folate receptor family. http://togogenome.org/gene/7719:LOC100179739 ^@ http://purl.uniprot.org/uniprot/H2XT66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYYR1 family.|||Membrane http://togogenome.org/gene/7719:LOC100177280 ^@ http://purl.uniprot.org/uniprot/A0A1W2WJC4 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/7719:LOC100187385 ^@ http://purl.uniprot.org/uniprot/F6YG96 ^@ Similarity ^@ Belongs to the PPR family. P subfamily. http://togogenome.org/gene/7719:LOC778698 ^@ http://purl.uniprot.org/uniprot/F6XKF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100184381 ^@ http://purl.uniprot.org/uniprot/F6S8Y1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/7719:LOC100184889 ^@ http://purl.uniprot.org/uniprot/F6XU45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM138 family.|||Membrane|||Required for ciliogenesis.|||Vacuole membrane http://togogenome.org/gene/7719:LOC100185517 ^@ http://purl.uniprot.org/uniprot/Q69HR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIEZO (TC 1.A.75) family.|||Membrane http://togogenome.org/gene/7719:LOC100184252 ^@ http://purl.uniprot.org/uniprot/H2Y1H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||May be involved in fusion of ER-derived transport vesicles with the Golgi complex.|||Membrane http://togogenome.org/gene/7719:smad2/3a ^@ http://purl.uniprot.org/uniprot/Q4H2T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:tgfbeta-na3 ^@ http://purl.uniprot.org/uniprot/A4PIG3 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100178216 ^@ http://purl.uniprot.org/uniprot/F6UUL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/7719:LOC100183218 ^@ http://purl.uniprot.org/uniprot/H2XJN8 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/7719:LOC100181505 ^@ http://purl.uniprot.org/uniprot/F6T4U7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. http://togogenome.org/gene/7719:LOC100186682 ^@ http://purl.uniprot.org/uniprot/H2XS14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7719:zf(c3h) ^@ http://purl.uniprot.org/uniprot/Q4H2G7 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100176622 ^@ http://purl.uniprot.org/uniprot/F6R1K9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.|||Membrane|||Microsome membrane http://togogenome.org/gene/7719:LOC100180823 ^@ http://purl.uniprot.org/uniprot/F6Z1X8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:zf(cchc)-13 ^@ http://purl.uniprot.org/uniprot/Q1RLD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BBP/SF1 family.|||Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.|||Nucleus http://togogenome.org/gene/7719:LOC100181499 ^@ http://purl.uniprot.org/uniprot/H2Y0I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR1 family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/7719:LOC100187330 ^@ http://purl.uniprot.org/uniprot/H2XZG7 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/7719:LOC100182334 ^@ http://purl.uniprot.org/uniprot/F6TMT5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100184477 ^@ http://purl.uniprot.org/uniprot/F6VT08 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. http://togogenome.org/gene/7719:LOC100179535 ^@ http://purl.uniprot.org/uniprot/A0A1W2WIN6 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/7719:LOC100178172 ^@ http://purl.uniprot.org/uniprot/F6ZDJ9 ^@ Similarity ^@ Belongs to the UPF0561 family. http://togogenome.org/gene/7719:LOC100176127 ^@ http://purl.uniprot.org/uniprot/F6T9X3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:LOC100176177 ^@ http://purl.uniprot.org/uniprot/F6YQL6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/7719:admp ^@ http://purl.uniprot.org/uniprot/Q4H3X4 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:six45 ^@ http://purl.uniprot.org/uniprot/Q4H2T8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100183461 ^@ http://purl.uniprot.org/uniprot/H2Y234 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/7719:LOC778831 ^@ http://purl.uniprot.org/uniprot/Q4H2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZFPL1 family.|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7719:LOC100184115 ^@ http://purl.uniprot.org/uniprot/F6TI40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingosine N-acyltransferase family.|||Membrane http://togogenome.org/gene/7719:mT ^@ http://purl.uniprot.org/uniprot/Q75UK0 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7719:spt4 ^@ http://purl.uniprot.org/uniprot/Q4H2R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.|||Nucleus http://togogenome.org/gene/7719:LOC100181326 ^@ http://purl.uniprot.org/uniprot/F7BI82 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100183853 ^@ http://purl.uniprot.org/uniprot/A0A1W3JGZ9 ^@ Similarity ^@ Belongs to the PTPS family. http://togogenome.org/gene/7719:adh3 ^@ http://purl.uniprot.org/uniprot/Q8WS90 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/7719:LOC100186402 ^@ http://purl.uniprot.org/uniprot/A0A1W5BF98 ^@ Similarity ^@ Belongs to the DIPK family. http://togogenome.org/gene/7719:sec61g ^@ http://purl.uniprot.org/uniprot/Q8I7D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma (By similarity). Component of the ribosome-associated ER translocon complex (By similarity).|||Necessary for protein translocation in the endoplasmic reticulum and multi-pass membrane protein biogenesis. http://togogenome.org/gene/7719:LOC100182370 ^@ http://purl.uniprot.org/uniprot/H2XNI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the p22phox family.|||Cell membrane|||Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.|||Membrane http://togogenome.org/gene/7719:bf-2 ^@ http://purl.uniprot.org/uniprot/Q5H875 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:LOC100175950 ^@ http://purl.uniprot.org/uniprot/H2XQA6 ^@ Similarity ^@ Belongs to the UPF0598 family. http://togogenome.org/gene/7719:LOC100176941 ^@ http://purl.uniprot.org/uniprot/F6VIA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the EF-1-beta/EF-1-delta family.|||EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.|||EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. http://togogenome.org/gene/7719:LOC100175624 ^@ http://purl.uniprot.org/uniprot/F6Y4V4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100179935 ^@ http://purl.uniprot.org/uniprot/F6YFU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/7719:fli/erg2 ^@ http://purl.uniprot.org/uniprot/Q4H3K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:LOC100179838 ^@ http://purl.uniprot.org/uniprot/F6PZM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:hox13 ^@ http://purl.uniprot.org/uniprot/Q4H3C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7719:pellino ^@ http://purl.uniprot.org/uniprot/Q9NDP9 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/7719:LOC100184014 ^@ http://purl.uniprot.org/uniprot/F6UW46 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/7719:LOC100185836 ^@ http://purl.uniprot.org/uniprot/H2Y1B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Cleavage furrow|||Endosome membrane|||Midbody ring|||Recycling endosome membrane|||filopodium membrane http://togogenome.org/gene/7719:LOC100186387 ^@ http://purl.uniprot.org/uniprot/F7AWS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100181621 ^@ http://purl.uniprot.org/uniprot/F6QBZ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:siat4 ^@ http://purl.uniprot.org/uniprot/F6XP52|||http://purl.uniprot.org/uniprot/Q702S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/7719:LOC100182516 ^@ http://purl.uniprot.org/uniprot/H2XNZ7 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/7719:LOC100184417 ^@ http://purl.uniprot.org/uniprot/A0A1W3JKJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100185254 ^@ http://purl.uniprot.org/uniprot/F6VE17 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/7719:LOC100176071 ^@ http://purl.uniprot.org/uniprot/F7J187 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cholesterol 7-desaturase family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol. Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.|||Membrane http://togogenome.org/gene/7719:LOC100181469 ^@ http://purl.uniprot.org/uniprot/H2Y143 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:zf(c2h2)-129 ^@ http://purl.uniprot.org/uniprot/Q1RL96 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100176025 ^@ http://purl.uniprot.org/uniprot/A0A1W3JNN9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100177336 ^@ http://purl.uniprot.org/uniprot/F6SAW5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7719:LOC100181913 ^@ http://purl.uniprot.org/uniprot/F7B3M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/7719:six12 ^@ http://purl.uniprot.org/uniprot/A0A1W2VNV2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:e2f1/2/3/6 ^@ http://purl.uniprot.org/uniprot/Q4H3N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/7719:LOC100178029 ^@ http://purl.uniprot.org/uniprot/F6TGV4 ^@ Similarity ^@ Belongs to the dymeclin family. http://togogenome.org/gene/7719:LOC100177792 ^@ http://purl.uniprot.org/uniprot/F6VDL8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100181177 ^@ http://purl.uniprot.org/uniprot/F6Y8A2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100180175 ^@ http://purl.uniprot.org/uniprot/F6WKL8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:dazap2-like ^@ http://purl.uniprot.org/uniprot/Q5QHQ8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus speckle|||nuclear body http://togogenome.org/gene/7719:LOC100184193 ^@ http://purl.uniprot.org/uniprot/F6TL82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:fli/erg1 ^@ http://purl.uniprot.org/uniprot/Q4H3K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:nab1/2 ^@ http://purl.uniprot.org/uniprot/Q4H345 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAB family.|||Homomultimers may associate with EGR1 bound to DNA.|||Nucleus http://togogenome.org/gene/7719:vglut ^@ http://purl.uniprot.org/uniprot/A8J6T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100181072 ^@ http://purl.uniprot.org/uniprot/F6X0F3 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/7719:ppar ^@ http://purl.uniprot.org/uniprot/Q4H2X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC100183289 ^@ http://purl.uniprot.org/uniprot/F6YI25 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/7719:dll-c ^@ http://purl.uniprot.org/uniprot/Q9GP87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178444 ^@ http://purl.uniprot.org/uniprot/H2XYF5 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7719:LOC100182393 ^@ http://purl.uniprot.org/uniprot/F6ZVC8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Cell projection|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/7719:LOC100183767 ^@ http://purl.uniprot.org/uniprot/F6QI77 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/7719:LOC100186452 ^@ http://purl.uniprot.org/uniprot/F7AGU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/7719:LOC101242316 ^@ http://purl.uniprot.org/uniprot/F6U8Z7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/7719:ephrin-a ^@ http://purl.uniprot.org/uniprot/Q4H3M2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7719:LOC100178719 ^@ http://purl.uniprot.org/uniprot/F6TUG7 ^@ Function|||Similarity ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB6 subunit family. http://togogenome.org/gene/7719:ciad70l24 ^@ http://purl.uniprot.org/uniprot/F6X383|||http://purl.uniprot.org/uniprot/Q8IU30 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7719:alpha-FucT ^@ http://purl.uniprot.org/uniprot/Q86SC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:LOC100176076 ^@ http://purl.uniprot.org/uniprot/F6YVI2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178024 ^@ http://purl.uniprot.org/uniprot/A0A1W5BE54 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:ssrp1 ^@ http://purl.uniprot.org/uniprot/Q4H2R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA (By similarity).|||Component of the FACT complex, a stable heterodimer of SSRP1 and SUPT16H. May also be a component of a CK2-SPT16-SSRP1 complex, composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B (By similarity).|||Nucleus|||nucleolus http://togogenome.org/gene/7719:LOC100181460 ^@ http://purl.uniprot.org/uniprot/H2XW42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7719:LOC101242258 ^@ http://purl.uniprot.org/uniprot/H2XTR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/7719:LOC100183963 ^@ http://purl.uniprot.org/uniprot/H2XQX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7719:zf(fyve)-4 ^@ http://purl.uniprot.org/uniprot/Q1RPY9 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/7719:chat ^@ http://purl.uniprot.org/uniprot/Q8T8B7 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/7719:LOC100177199 ^@ http://purl.uniprot.org/uniprot/H2XUX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100184221 ^@ http://purl.uniprot.org/uniprot/F6QE62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCO1/2 family.|||Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.|||Homodimer.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:gsc ^@ http://purl.uniprot.org/uniprot/Q4H3E8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100182647 ^@ http://purl.uniprot.org/uniprot/H2XUT9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100180378 ^@ http://purl.uniprot.org/uniprot/H2XVM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIQK family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7719:hnf1 ^@ http://purl.uniprot.org/uniprot/Q4H3D7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100186658 ^@ http://purl.uniprot.org/uniprot/F6QA84 ^@ Similarity ^@ Belongs to the MS4A family. http://togogenome.org/gene/7719:zf(traf/ring)-1 ^@ http://purl.uniprot.org/uniprot/Q1RQ04 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:LOC100184616 ^@ http://purl.uniprot.org/uniprot/A0A1W3JF95 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/7719:LOC100186020 ^@ http://purl.uniprot.org/uniprot/F6XRM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/7719:LOC100184793 ^@ http://purl.uniprot.org/uniprot/F6Q1R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7719:deltex ^@ http://purl.uniprot.org/uniprot/Q4H3Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Deltex family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100176837 ^@ http://purl.uniprot.org/uniprot/H2XTI8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7719:LOC100182896 ^@ http://purl.uniprot.org/uniprot/H2XZ76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. http://togogenome.org/gene/7719:LOC100182507 ^@ http://purl.uniprot.org/uniprot/Q70KQ6 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/7719:zf(rbz)-3 ^@ http://purl.uniprot.org/uniprot/Q1RL65 ^@ Similarity ^@ Belongs to the peptidase C64 family. http://togogenome.org/gene/7719:zf(c2h2)-86 ^@ http://purl.uniprot.org/uniprot/F6ZQ39 ^@ Similarity ^@ Belongs to the CWC15 family. http://togogenome.org/gene/7719:LOC100185040 ^@ http://purl.uniprot.org/uniprot/A0A1W2WKU4 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/7719:LOC100180314 ^@ http://purl.uniprot.org/uniprot/F6U1Z9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100179693 ^@ http://purl.uniprot.org/uniprot/F6WKB8 ^@ Function|||Similarity ^@ As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.|||Belongs to the CIA30 family. http://togogenome.org/gene/7719:LOC100183994 ^@ http://purl.uniprot.org/uniprot/H2XPJ9 ^@ Similarity ^@ Belongs to the glycosyltransferase 25 family. http://togogenome.org/gene/7719:LOC100184857 ^@ http://purl.uniprot.org/uniprot/A0A1W2WKT4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/7719:LOC100178850 ^@ http://purl.uniprot.org/uniprot/F6XI54 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC778716 ^@ http://purl.uniprot.org/uniprot/Q4H316 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179801 ^@ http://purl.uniprot.org/uniprot/F6YQV7 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/7719:LOC100182378 ^@ http://purl.uniprot.org/uniprot/A0A1W2WNJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS3 family.|||Mitochondrion http://togogenome.org/gene/7719:LOC100183592 ^@ http://purl.uniprot.org/uniprot/F6TMN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN4 family.|||Nucleus|||Vesicle|||synaptic vesicle http://togogenome.org/gene/7719:tardbp ^@ http://purl.uniprot.org/uniprot/Q4H2Q6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100183087 ^@ http://purl.uniprot.org/uniprot/F7AZ18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.|||Membrane http://togogenome.org/gene/7719:LOC100185209 ^@ http://purl.uniprot.org/uniprot/F6U351 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7719:LOC100185771 ^@ http://purl.uniprot.org/uniprot/A0A1W2W3E0 ^@ Similarity ^@ Belongs to the tropomyosin family. http://togogenome.org/gene/7719:fut13 ^@ http://purl.uniprot.org/uniprot/Q7YZS7 ^@ Similarity ^@ Belongs to the glycosyltransferase 68 family. http://togogenome.org/gene/7719:ikk-epsilon ^@ http://purl.uniprot.org/uniprot/F7A8T7|||http://purl.uniprot.org/uniprot/Q4H3C0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7719:bmp3 ^@ http://purl.uniprot.org/uniprot/Q4H3U5 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100187260 ^@ http://purl.uniprot.org/uniprot/F6WSV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7719:nf-il2 ^@ http://purl.uniprot.org/uniprot/Q4H349 ^@ Similarity ^@ Belongs to the bZIP family. NFIL3 subfamily. http://togogenome.org/gene/7719:LOC104265690 ^@ http://purl.uniprot.org/uniprot/A0A1W5B570 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Cytoplasm http://togogenome.org/gene/7719:zeta ^@ http://purl.uniprot.org/uniprot/H2XVD5|||http://purl.uniprot.org/uniprot/O18314 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:tensin ^@ http://purl.uniprot.org/uniprot/Q86SD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PTEN phosphatase protein family.|||focal adhesion http://togogenome.org/gene/7719:LOC100179669 ^@ http://purl.uniprot.org/uniprot/F6ZYU1 ^@ Function|||Similarity ^@ Belongs to the GST superfamily. Omega family.|||Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). http://togogenome.org/gene/7719:cam ^@ http://purl.uniprot.org/uniprot/O02367 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the calmodulin family.|||Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.|||This protein has four functional calcium-binding sites. http://togogenome.org/gene/7719:rar ^@ http://purl.uniprot.org/uniprot/Q4H2W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7719:irx-a ^@ http://purl.uniprot.org/uniprot/Q4H3A8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100187027 ^@ http://purl.uniprot.org/uniprot/H2XLK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/7719:foxi-c ^@ http://purl.uniprot.org/uniprot/Q4H3I4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100181638 ^@ http://purl.uniprot.org/uniprot/A0A1W5BDY9 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/7719:LOC100183090 ^@ http://purl.uniprot.org/uniprot/F6RID7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer.|||It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.|||Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. http://togogenome.org/gene/7719:LOC100179315 ^@ http://purl.uniprot.org/uniprot/F6XIQ9 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/7719:LOC100184404 ^@ http://purl.uniprot.org/uniprot/A0A1W2W8I4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/7719:LOC100181735 ^@ http://purl.uniprot.org/uniprot/F7A7L0 ^@ Similarity ^@ Belongs to the SCAR/WAVE family. http://togogenome.org/gene/7719:LOC100184340 ^@ http://purl.uniprot.org/uniprot/F6WIJ0 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/7719:LOC100176985 ^@ http://purl.uniprot.org/uniprot/F6THW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100184134 ^@ http://purl.uniprot.org/uniprot/F6T8C7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:LOC100175439 ^@ http://purl.uniprot.org/uniprot/F6ZH72 ^@ Function|||Similarity ^@ Belongs to the ataxin-10 family.|||Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. http://togogenome.org/gene/7719:LOC100180876 ^@ http://purl.uniprot.org/uniprot/F6Z0S6 ^@ Function ^@ Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. http://togogenome.org/gene/7719:hoxa2 ^@ http://purl.uniprot.org/uniprot/Q9BMT5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100178239 ^@ http://purl.uniprot.org/uniprot/F7BQ61 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/7719:LOC100176247 ^@ http://purl.uniprot.org/uniprot/F6T6F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/7719:LOC100177853 ^@ http://purl.uniprot.org/uniprot/H2XW44 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7719:LOC100180840 ^@ http://purl.uniprot.org/uniprot/F6ZRG6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/7719:LOC100177402 ^@ http://purl.uniprot.org/uniprot/F6U1E2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/7719:LOC100183401 ^@ http://purl.uniprot.org/uniprot/F7B503 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC4 family.|||Component of the origin recognition complex (ORC) that binds origins of replication.|||Nucleus http://togogenome.org/gene/7719:LOC101243120 ^@ http://purl.uniprot.org/uniprot/H2XTD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/7719:LOC100181494 ^@ http://purl.uniprot.org/uniprot/F6YGU3 ^@ Similarity ^@ Belongs to the IAP family. http://togogenome.org/gene/7719:LOC100180068 ^@ http://purl.uniprot.org/uniprot/F7ASN6 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/7719:LOC100184189 ^@ http://purl.uniprot.org/uniprot/Q86D88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GnRH family.|||Secreted http://togogenome.org/gene/7719:LOC100186137 ^@ http://purl.uniprot.org/uniprot/F7BD57 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/7719:LOC100183351 ^@ http://purl.uniprot.org/uniprot/F7A1H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/7719:LOC100179796 ^@ http://purl.uniprot.org/uniprot/F6T511 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/7719:zf(ring)-20 ^@ http://purl.uniprot.org/uniprot/F6SWH7|||http://purl.uniprot.org/uniprot/Q1RPV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS41 family.|||Early endosome membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.|||Vesicle|||clathrin-coated vesicle|||trans-Golgi network http://togogenome.org/gene/7719:rxr ^@ http://purl.uniprot.org/uniprot/Q4H2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Nucleus http://togogenome.org/gene/7719:LOC108949918 ^@ http://purl.uniprot.org/uniprot/H2Y2F8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100178283 ^@ http://purl.uniprot.org/uniprot/F7AX45 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/7719:LOC100177746 ^@ http://purl.uniprot.org/uniprot/F6QHV8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100176776 ^@ http://purl.uniprot.org/uniprot/F7AX27 ^@ Similarity ^@ Belongs to the HINT family. http://togogenome.org/gene/7719:LOC100185443 ^@ http://purl.uniprot.org/uniprot/F6R2L1 ^@ Similarity ^@ Belongs to the Flattop family. http://togogenome.org/gene/7719:nox2 ^@ http://purl.uniprot.org/uniprot/A7E3L0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100178419 ^@ http://purl.uniprot.org/uniprot/F6XJ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/7719:LOC100176981 ^@ http://purl.uniprot.org/uniprot/F6YV39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:nat2 ^@ http://purl.uniprot.org/uniprot/D8FT00 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/7719:LOC100181945 ^@ http://purl.uniprot.org/uniprot/H2XV14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7719:LOC100179977 ^@ http://purl.uniprot.org/uniprot/F6SS76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/7719:LOC100184554 ^@ http://purl.uniprot.org/uniprot/F6VWZ6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179830 ^@ http://purl.uniprot.org/uniprot/F7A9T3 ^@ Similarity ^@ Belongs to the UXT family. http://togogenome.org/gene/7719:LOC100178709 ^@ http://purl.uniprot.org/uniprot/F6QB20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/7719:LOC494405 ^@ http://purl.uniprot.org/uniprot/Q69HM1 ^@ Similarity ^@ Belongs to the FAM98 family. http://togogenome.org/gene/7719:c/ebpalpha/gamma ^@ http://purl.uniprot.org/uniprot/Q4H3U0 ^@ Similarity ^@ Belongs to the bZIP family. C/EBP subfamily. http://togogenome.org/gene/7719:LOC100175194 ^@ http://purl.uniprot.org/uniprot/F6WL94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane http://togogenome.org/gene/7719:LOC100178296 ^@ http://purl.uniprot.org/uniprot/F6VKL4 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/7719:nkx-c ^@ http://purl.uniprot.org/uniprot/Q4H338 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185391 ^@ http://purl.uniprot.org/uniprot/H2XPZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7719:LOC100181359 ^@ http://purl.uniprot.org/uniprot/F6XUY3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7719:LOC100179626 ^@ http://purl.uniprot.org/uniprot/F7B5B2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/7719:zf(dhhc)-5 ^@ http://purl.uniprot.org/uniprot/Q1RPU4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7719:sfrp2 ^@ http://purl.uniprot.org/uniprot/Q4H2U4 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:zf(ubp)-3 ^@ http://purl.uniprot.org/uniprot/Q1RL25 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/7719:LOC100180707 ^@ http://purl.uniprot.org/uniprot/H2Y2L0 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/7719:LOC100176560 ^@ http://purl.uniprot.org/uniprot/F6VYM6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/7719:LOC100177170 ^@ http://purl.uniprot.org/uniprot/F6W2G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.|||Homodimer. http://togogenome.org/gene/7719:il-17-2 ^@ http://purl.uniprot.org/uniprot/Q6L5M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-17 family.|||Secreted http://togogenome.org/gene/7719:bach ^@ http://purl.uniprot.org/uniprot/Q4H3V4 ^@ Similarity ^@ Belongs to the bZIP family. CNC subfamily. http://togogenome.org/gene/7719:atg5 ^@ http://purl.uniprot.org/uniprot/Q3MQ22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG5 family.|||Conjugated with ATG12.|||Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.|||May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.|||Preautophagosomal structure membrane http://togogenome.org/gene/7719:LOC100176424 ^@ http://purl.uniprot.org/uniprot/F6PM63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase D subunit family.|||clathrin-coated vesicle membrane http://togogenome.org/gene/7719:LOC100186038 ^@ http://purl.uniprot.org/uniprot/F6Y011 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. http://togogenome.org/gene/7719:LOC100181765 ^@ http://purl.uniprot.org/uniprot/F6W248 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/7719:LOC100184934 ^@ http://purl.uniprot.org/uniprot/F6RED0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ4 family.|||Component of a multi-subunit COQ enzyme complex.|||Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.|||Mitochondrion inner membrane http://togogenome.org/gene/7719:LOC100187546 ^@ http://purl.uniprot.org/uniprot/H2XW68 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:ap-2-like2 ^@ http://purl.uniprot.org/uniprot/Q4H3W9 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/7719:LOC100186749 ^@ http://purl.uniprot.org/uniprot/F6UHS2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer.|||Nucleus http://togogenome.org/gene/7719:LOC100185398 ^@ http://purl.uniprot.org/uniprot/A0A1W2W8E5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:LOC100177652 ^@ http://purl.uniprot.org/uniprot/A0A1W3JGH5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/7719:LOC104266244 ^@ http://purl.uniprot.org/uniprot/H2XQF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/7719:LOC100175401 ^@ http://purl.uniprot.org/uniprot/F6Y354 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100186600 ^@ http://purl.uniprot.org/uniprot/F6VF47 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100179894 ^@ http://purl.uniprot.org/uniprot/F6Z6H7 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/7719:LOC100181785 ^@ http://purl.uniprot.org/uniprot/F6ZVS4 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/7719:LOC100181821 ^@ http://purl.uniprot.org/uniprot/F6R4H2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7719:LOC100184963 ^@ http://purl.uniprot.org/uniprot/F7AAS8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/7719:LOC100183093 ^@ http://purl.uniprot.org/uniprot/H2XLK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||cis-Golgi network http://togogenome.org/gene/7719:hspa12a ^@ http://purl.uniprot.org/uniprot/C7G1W1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/7719:tram1/2 ^@ http://purl.uniprot.org/uniprot/Q68A32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/7719:LOC108949444 ^@ http://purl.uniprot.org/uniprot/H2XQR2 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/7719:bmp2/4 ^@ http://purl.uniprot.org/uniprot/Q4H3U6 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100184240 ^@ http://purl.uniprot.org/uniprot/F6S2W5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100185310 ^@ http://purl.uniprot.org/uniprot/H2XS31 ^@ Function|||Similarity ^@ Belongs to the BMT2 family.|||S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/7719:sfrp3/4-b ^@ http://purl.uniprot.org/uniprot/Q4H2U2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100183814 ^@ http://purl.uniprot.org/uniprot/F6VBY8 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/7719:LOC100186956 ^@ http://purl.uniprot.org/uniprot/F7ATI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/7719:LOC100179970 ^@ http://purl.uniprot.org/uniprot/F6VEB2 ^@ Function|||Similarity ^@ Belongs to the WD repeat CIA1 family.|||Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. http://togogenome.org/gene/7719:LOC100180921 ^@ http://purl.uniprot.org/uniprot/F6Y8H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.|||Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.|||Cytoplasm|||Monomer and homodimer.|||Nucleus http://togogenome.org/gene/7719:LOC100180168 ^@ http://purl.uniprot.org/uniprot/F6U8F3 ^@ Similarity ^@ Belongs to the LSM14 family. http://togogenome.org/gene/7719:LOC100180090 ^@ http://purl.uniprot.org/uniprot/A0A1W3JQF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/7719:LOC100181802 ^@ http://purl.uniprot.org/uniprot/F6TXG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100179869 ^@ http://purl.uniprot.org/uniprot/F7BFF4 ^@ Similarity ^@ Belongs to the HUS1 family. http://togogenome.org/gene/7719:lefty/antivin ^@ http://purl.uniprot.org/uniprot/Q4H393 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100176189 ^@ http://purl.uniprot.org/uniprot/H2XYF8 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/7719:LOC100179473 ^@ http://purl.uniprot.org/uniprot/F6SK29 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/7719:pou-iv ^@ http://purl.uniprot.org/uniprot/Q4H2X8|||http://purl.uniprot.org/uniprot/Q5IFL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7719:lag1-like1 ^@ http://purl.uniprot.org/uniprot/Q4H396 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7719:LOC100183508 ^@ http://purl.uniprot.org/uniprot/F6S840 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EAF7 family.|||Nucleus http://togogenome.org/gene/7719:wnt3 ^@ http://purl.uniprot.org/uniprot/Q4H2M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7719:LOC100178536 ^@ http://purl.uniprot.org/uniprot/F6S3S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/7719:pax2/5/8-b ^@ http://purl.uniprot.org/uniprot/Q4H2Z2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100177118 ^@ http://purl.uniprot.org/uniprot/F6YKX8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/7719:LOC100177969 ^@ http://purl.uniprot.org/uniprot/F6S8U4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/7719:elo ^@ http://purl.uniprot.org/uniprot/Q5SE06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/7719:LOC100186466 ^@ http://purl.uniprot.org/uniprot/F7A5H4 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/7719:smad1/5 ^@ http://purl.uniprot.org/uniprot/Q4H2T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100182755 ^@ http://purl.uniprot.org/uniprot/F6Q2J9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/7719:LOC100182231 ^@ http://purl.uniprot.org/uniprot/F6YND1 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/7719:LOC100185196 ^@ http://purl.uniprot.org/uniprot/F6W1H2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. http://togogenome.org/gene/7719:aer61 ^@ http://purl.uniprot.org/uniprot/Q5NDL8 ^@ Similarity ^@ Belongs to the glycosyltransferase 61 family. http://togogenome.org/gene/7719:LOC100186995 ^@ http://purl.uniprot.org/uniprot/F6WAG8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/7719:LOC100185261 ^@ http://purl.uniprot.org/uniprot/F6XYG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7719:titf1 ^@ http://purl.uniprot.org/uniprot/O96738 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100177411 ^@ http://purl.uniprot.org/uniprot/F6RHA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Dynein axonemal particle http://togogenome.org/gene/7719:LOC100176797 ^@ http://purl.uniprot.org/uniprot/A0A1W2WEN5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7719:LOC100178968 ^@ http://purl.uniprot.org/uniprot/F6WCR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||Nucleus http://togogenome.org/gene/7719:LOC100180975 ^@ http://purl.uniprot.org/uniprot/H2XME3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/7719:hb4 ^@ http://purl.uniprot.org/uniprot/Q70PH6 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7719:LOC100181113 ^@ http://purl.uniprot.org/uniprot/F6Q021 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/7719:LOC100180409 ^@ http://purl.uniprot.org/uniprot/A0A1W3JIQ6 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/7719:LOC100176117 ^@ http://purl.uniprot.org/uniprot/F6QPI8 ^@ Similarity ^@ Belongs to the SAPAP family. http://togogenome.org/gene/7719:scalloped/tef1 ^@ http://purl.uniprot.org/uniprot/Q4H2U7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:fgf9/16/20 ^@ http://purl.uniprot.org/uniprot/Q8I6J4 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7719:LOC100182277 ^@ http://purl.uniprot.org/uniprot/F6PYH8 ^@ Similarity ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/7719:LOC100185279 ^@ http://purl.uniprot.org/uniprot/A0A1W5B7P7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/7719:LOC100182182 ^@ http://purl.uniprot.org/uniprot/F6QN62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100184285 ^@ http://purl.uniprot.org/uniprot/F6ZED0 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/7719:LOC100184605 ^@ http://purl.uniprot.org/uniprot/F6WVC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2H phosphoesterase superfamily. USB1 family.|||Nucleus|||Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA. http://togogenome.org/gene/7719:LOC100183493 ^@ http://purl.uniprot.org/uniprot/F6YWK0 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. http://togogenome.org/gene/7719:LOC100181451 ^@ http://purl.uniprot.org/uniprot/F6V4V8 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7719:LOC494357 ^@ http://purl.uniprot.org/uniprot/Q69HS9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:thbsbi ^@ http://purl.uniprot.org/uniprot/A2SY08 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:pax6 ^@ http://purl.uniprot.org/uniprot/Q8TA62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/7719:LOC100187134 ^@ http://purl.uniprot.org/uniprot/F6QCQ5 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/7719:LOC100179078 ^@ http://purl.uniprot.org/uniprot/F6R255 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/7719:LOC100175065 ^@ http://purl.uniprot.org/uniprot/F7AD61 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7719:tgfbeta-na1 ^@ http://purl.uniprot.org/uniprot/Q4H2P7 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7719:LOC100183606 ^@ http://purl.uniprot.org/uniprot/F6ZA98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MoaE family. MOCS2B subfamily.|||Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.|||Cytoplasm|||Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits. http://togogenome.org/gene/7719:ins-l1 ^@ http://purl.uniprot.org/uniprot/Q0GTF8 ^@ Similarity ^@ Belongs to the insulin family. http://togogenome.org/gene/7719:LOC100176574 ^@ http://purl.uniprot.org/uniprot/F6YXJ6 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/7719:gat-like ^@ http://purl.uniprot.org/uniprot/Q1RPY7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100181703 ^@ http://purl.uniprot.org/uniprot/F6Z3S5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family. http://togogenome.org/gene/7719:LOC100180339 ^@ http://purl.uniprot.org/uniprot/F6XYQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100183612 ^@ http://purl.uniprot.org/uniprot/F7BP46 ^@ Similarity ^@ Belongs to the TMEM9 family. http://togogenome.org/gene/7719:LOC100175865 ^@ http://purl.uniprot.org/uniprot/F6PP67 ^@ Similarity ^@ Belongs to the HPF1 family. http://togogenome.org/gene/7719:LOC100179207 ^@ http://purl.uniprot.org/uniprot/F7AD29 ^@ Similarity ^@ Belongs to the uroporphyrinogen-III synthase family. http://togogenome.org/gene/7719:LOC100181596 ^@ http://purl.uniprot.org/uniprot/H2XJX4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/7719:LOC100183715 ^@ http://purl.uniprot.org/uniprot/F6UJ88 ^@ Similarity ^@ Belongs to the Asterix family. http://togogenome.org/gene/7719:LOC100176963 ^@ http://purl.uniprot.org/uniprot/F6W6R6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/7719:LOC100181290 ^@ http://purl.uniprot.org/uniprot/F6UBJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7719:hlx ^@ http://purl.uniprot.org/uniprot/Q4H3E1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100177768 ^@ http://purl.uniprot.org/uniprot/H2XM97 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/7719:zf(cchc)-20 ^@ http://purl.uniprot.org/uniprot/Q1RPW7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX41 subfamily. http://togogenome.org/gene/7719:LOC100176337 ^@ http://purl.uniprot.org/uniprot/H2XN89 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/7719:LOC100186196 ^@ http://purl.uniprot.org/uniprot/F7B7C2 ^@ Similarity ^@ Belongs to the CKAP2 family. http://togogenome.org/gene/7719:LOC100177460 ^@ http://purl.uniprot.org/uniprot/H2XK85 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7719:LOC100183714 ^@ http://purl.uniprot.org/uniprot/H2Y0X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100184706 ^@ http://purl.uniprot.org/uniprot/H2XML9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane http://togogenome.org/gene/7719:LOC100185787 ^@ http://purl.uniprot.org/uniprot/F6U696 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7719:LOC494363 ^@ http://purl.uniprot.org/uniprot/Q69HS3 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. http://togogenome.org/gene/7719:LOC100178779 ^@ http://purl.uniprot.org/uniprot/F6YHI5 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7719:p47phox ^@ http://purl.uniprot.org/uniprot/Q4R1Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SH3PXD2 family.|||Cytoplasm http://togogenome.org/gene/7719:fut8 ^@ http://purl.uniprot.org/uniprot/Q8IFW8|||http://purl.uniprot.org/uniprot/Q8IFW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 23 family.|||Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.|||Golgi stack membrane http://togogenome.org/gene/7719:LOC100182102 ^@ http://purl.uniprot.org/uniprot/F7BL29 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7719:LOC100177017 ^@ http://purl.uniprot.org/uniprot/H2XU70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7719:LOC100177421 ^@ http://purl.uniprot.org/uniprot/H2XY48 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/7719:LOC100178371 ^@ http://purl.uniprot.org/uniprot/F6WHS2 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/7719:LOC100187185 ^@ http://purl.uniprot.org/uniprot/A0A1W5B5J3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7719:LOC100177752 ^@ http://purl.uniprot.org/uniprot/F6QXH6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/7719:LOC100181185 ^@ http://purl.uniprot.org/uniprot/A0A1W5B6R5 ^@ Similarity ^@ Belongs to the BCP1 family. http://togogenome.org/gene/7719:LOC100179548 ^@ http://purl.uniprot.org/uniprot/H2XWB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/7719:LOC100181599 ^@ http://purl.uniprot.org/uniprot/F6SSS2 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/7719:LOC100179651 ^@ http://purl.uniprot.org/uniprot/F6S4A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/7719:LOC100181046 ^@ http://purl.uniprot.org/uniprot/F6ZHC8|||http://purl.uniprot.org/uniprot/Q70SX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100186085 ^@ http://purl.uniprot.org/uniprot/F6PYR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYRI family.|||Membrane http://togogenome.org/gene/7719:LOC100184829 ^@ http://purl.uniprot.org/uniprot/F6TIT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/7719:LOC104265927 ^@ http://purl.uniprot.org/uniprot/F6X3S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.|||Cytoplasm http://togogenome.org/gene/7719:LOC100184985 ^@ http://purl.uniprot.org/uniprot/F6Y7W5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100183249 ^@ http://purl.uniprot.org/uniprot/A0A1W2WAR8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.|||Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7719:LOC100178391 ^@ http://purl.uniprot.org/uniprot/F6YVT2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7719:LOC100185540 ^@ http://purl.uniprot.org/uniprot/H2Y276 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7719:LOC100179571 ^@ http://purl.uniprot.org/uniprot/A0A1W2W635 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/7719:capzb ^@ http://purl.uniprot.org/uniprot/H2XUY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/7719:LOC100176570 ^@ http://purl.uniprot.org/uniprot/F6ULQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7719:LOC100185184 ^@ http://purl.uniprot.org/uniprot/F6QAF5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC100101826 ^@ http://purl.uniprot.org/uniprot/A4ZW71 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:LOC619278 ^@ http://purl.uniprot.org/uniprot/Q5VH52 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:tk ^@ http://purl.uniprot.org/uniprot/Q60GS9 ^@ Similarity ^@ Belongs to the tachykinin family. http://togogenome.org/gene/7719:elk ^@ http://purl.uniprot.org/uniprot/Q4H3N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7719:aptx ^@ http://purl.uniprot.org/uniprot/P61802 ^@ Domain|||Function|||Subcellular Location Annotation ^@ DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).|||The C2H2-type zinc finger mediates DNA-binding.|||The HIT domain is required for enzymatic activity.|||The histidine triad, also called HIT motif, forms part of the binding loop for the alpha-phosphate of purine mononucleotide.|||nucleolus|||nucleoplasm http://togogenome.org/gene/7719:LOC100184566 ^@ http://purl.uniprot.org/uniprot/F6QNI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/7719:LOC100187016 ^@ http://purl.uniprot.org/uniprot/H2XM22 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/7719:c/ebpbeta/delta/epsilon ^@ http://purl.uniprot.org/uniprot/Q4H3T9 ^@ Similarity ^@ Belongs to the bZIP family. C/EBP subfamily. http://togogenome.org/gene/7719:rsp3 ^@ http://purl.uniprot.org/uniprot/Q8T898 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the flagellar radial spoke RSP3 family.|||flagellum axoneme http://togogenome.org/gene/7719:LOC100186031 ^@ http://purl.uniprot.org/uniprot/H2Y0D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm http://togogenome.org/gene/7719:LOC100183014 ^@ http://purl.uniprot.org/uniprot/A0A1W2WQI1 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/7719:LOC100187490 ^@ http://purl.uniprot.org/uniprot/F6Z9B3 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/7719:LOC100182982 ^@ http://purl.uniprot.org/uniprot/F6Z8E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/7719:LOC100176126 ^@ http://purl.uniprot.org/uniprot/F6VMY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/7719:prx1 ^@ http://purl.uniprot.org/uniprot/Q9BI30 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100185183 ^@ http://purl.uniprot.org/uniprot/F6SQ23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/7719:mox ^@ http://purl.uniprot.org/uniprot/Q4H363 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7719:LOC100179971 ^@ http://purl.uniprot.org/uniprot/F6XY19 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/7719:LOC100186938 ^@ http://purl.uniprot.org/uniprot/F6U9F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Cytoplasm http://togogenome.org/gene/7719:LOC100177673 ^@ http://purl.uniprot.org/uniprot/H2XPG9 ^@ Similarity ^@ Belongs to the VPS25 family. http://togogenome.org/gene/7719:bf-1 ^@ http://purl.uniprot.org/uniprot/Q5H876 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7719:tgfbr-iia ^@ http://purl.uniprot.org/uniprot/Q4H2P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/7719:LOC101242403 ^@ http://purl.uniprot.org/uniprot/F6TVI5 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/7719:LOC100184944 ^@ http://purl.uniprot.org/uniprot/F6ZLT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-I/CTF3 family.|||Nucleus|||centromere http://togogenome.org/gene/7719:LOC474363 ^@ http://purl.uniprot.org/uniprot/Q69HR9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7719:not6 ^@ http://purl.uniprot.org/uniprot/Q9NDP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chondroitin N-acetylgalactosaminyltransferase family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/7719:LOC100180455 ^@ http://purl.uniprot.org/uniprot/A0A1W2WM83 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/7719:LOC100179545 ^@ http://purl.uniprot.org/uniprot/F6ZPU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/7719:zf(dhhc)-1 ^@ http://purl.uniprot.org/uniprot/Q1RPW1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7719:LOC100180419 ^@ http://purl.uniprot.org/uniprot/F7B376 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Golgi stack membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/7719:LOC100185883 ^@ http://purl.uniprot.org/uniprot/H2Y1Z9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Monomer. http://togogenome.org/gene/7719:LOC100180902 ^@ http://purl.uniprot.org/uniprot/F6ZXM0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7719:LOC100175631 ^@ http://purl.uniprot.org/uniprot/A0A1W3JF81 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7719:LOC100185831 ^@ http://purl.uniprot.org/uniprot/F6Y5B7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7719:LOC100182790 ^@ http://purl.uniprot.org/uniprot/H2XJS5 ^@ Similarity ^@ Belongs to the UPF0449 family. http://togogenome.org/gene/7719:LOC100184512 ^@ http://purl.uniprot.org/uniprot/F6YF45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/7719:LOC100186181 ^@ http://purl.uniprot.org/uniprot/F7A5J2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/7719:LOC100186199 ^@ http://purl.uniprot.org/uniprot/F6YLC1 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily.